dbPTM

CRK_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CRK_HUMAN
UniProt AC	P46108
Protein Name	Adapter molecule crk
Gene Name	CRK
Organism	Homo sapiens (Human).
Sequence Length	304
Subcellular Localization	Cytoplasm. Cell membrane. Translocated to the plasma membrane upon cell adhesion..
Protein Description	Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling..
Protein Sequence	MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQNPDEDFS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAGNFDSEE ------CCCCCCHHH	22.95	22223895
7	Phosphorylation	-MAGNFDSEERSSWY -CCCCCCHHHHHHCC	36.90	25690035
11	Phosphorylation	NFDSEERSSWYWGRL CCCHHHHHHCCCCCC	28.62	27251275
12	Phosphorylation	FDSEERSSWYWGRLS CCHHHHHHCCCCCCC	30.33	27251275
40	Phosphorylation	GVFLVRDSSTSPGDY EEEEEEECCCCCCCE	25.58	22167270
41	Phosphorylation	VFLVRDSSTSPGDYV EEEEEECCCCCCCEE	36.87	22167270
42	Phosphorylation	FLVRDSSTSPGDYVL EEEEECCCCCCCEEE	42.78	22167270
43	Phosphorylation	LVRDSSTSPGDYVLS EEEECCCCCCCEEEE	28.91	30266825
47	Phosphorylation	SSTSPGDYVLSVSEN CCCCCCCEEEEEECC	14.81	23403867
50	Phosphorylation	SPGDYVLSVSENSRV CCCCEEEEEECCCEE	17.35	23403867
52	Phosphorylation	GDYVLSVSENSRVSH CCEEEEEECCCEEEE	27.90	23403867
55	Phosphorylation	VLSVSENSRVSHYII EEEEECCCEEEEEEE	29.97	23403867
58	Phosphorylation	VSENSRVSHYIINSS EECCCEEEEEEECCC	14.95	23186163
60	Phosphorylation	ENSRVSHYIINSSGP CCCEEEEEEECCCCC	8.94	26091039
64	Phosphorylation	VSHYIINSSGPRPPV EEEEEECCCCCCCCC	26.68	26074081
65	Phosphorylation	SHYIINSSGPRPPVP EEEEECCCCCCCCCC	48.61	26074081
74	Phosphorylation	PRPPVPPSPAQPPPG CCCCCCCCCCCCCCC	27.14	26055452
83	Phosphorylation	AQPPPGVSPSRLRIG CCCCCCCCHHHCEEC	24.07	26055452
85	Phosphorylation	PPPGVSPSRLRIGDQ CCCCCCHHHCEECCC	36.12	22617229
96	Phosphorylation	IGDQEFDSLPALLEF ECCCCCCCHHHHHHH	41.39	26657352
108	Phosphorylation	LEFYKIHYLDTTTLI HHHHEEEEEECCEEE	15.11	23917254
111	Phosphorylation	YKIHYLDTTTLIEPV HEEEEEECCEEEEEC	21.05	27251275
112	Phosphorylation	KIHYLDTTTLIEPVS EEEEEECCEEEEECC	21.19	27251275
113	Phosphorylation	IHYLDTTTLIEPVSR EEEEECCEEEEECCC	28.03	27251275
119	Phosphorylation	TTLIEPVSRSRQGSG CEEEEECCCCCCCCE	34.94	30576142
121	Phosphorylation	LIEPVSRSRQGSGVI EEEECCCCCCCCEEE	22.81	29507054
122	Methylation	IEPVSRSRQGSGVIL EEECCCCCCCCEEEE	43.71	-
125	Phosphorylation	VSRSRQGSGVILRQE CCCCCCCCEEEECHH	22.88	25159151
136	Phosphorylation	LRQEEAEYVRALFDF ECHHHHHHHHHHHCC	11.41	25159151
154	2-Hydroxyisobutyrylation	DEEDLPFKKGDILRI CCCCCCCCCCCEEEE	54.64	-
154	Acetylation	DEEDLPFKKGDILRI CCCCCCCCCCCEEEE	54.64	24179697
175	Phosphorylation	QWWNAEDSEGKRGMI HCCCCCCCCCCCCCE	39.49	-
181	Sulfoxidation	DSEGKRGMIPVPYVE CCCCCCCCEECCCHH	3.48	30846556
190 (in isoform 2)	Phosphorylation	-	14.34	30266825
190	Phosphorylation	PVPYVEKYRPASASV ECCCHHCCCCCCCEE	14.34	26356563
194	Phosphorylation	VEKYRPASASVSALI HHCCCCCCCEEEHHC	24.61	20166139
194 (in isoform 2)	Phosphorylation	-	24.61	30266825
196	Phosphorylation	KYRPASASVSALIGG CCCCCCCEEEHHCCC	17.70	26356563
196 (in isoform 2)	Phosphorylation	-	17.70	30266825
198 (in isoform 2)	Phosphorylation	-	18.18	30266825
198	Phosphorylation	RPASASVSALIGGNQ CCCCCEEEHHCCCCC	18.18	26356563
208	Phosphorylation	IGGNQEGSHPQPLGG CCCCCCCCCCCCCCC	31.10	30576142
221	Phosphorylation	GGPEPGPYAQPSVNT CCCCCCCCCCCCCCC	24.63	8194526
225	Phosphorylation	PGPYAQPSVNTPLPN CCCCCCCCCCCCCCC	18.87	26356563
228	Phosphorylation	YAQPSVNTPLPNLQN CCCCCCCCCCCCCCC	24.85	26356563
239	Phosphorylation	NLQNGPIYARVIQKR CCCCCCEEEEEHHHH	7.47	17081983
251	Phosphorylation	QKRVPNAYDKTALAL HHHCCCCCCCHHHEE	25.31	21082442
253	Acetylation	RVPNAYDKTALALEV HCCCCCCCHHHEEEC	24.03	23954790
254	Phosphorylation	VPNAYDKTALALEVG CCCCCCCHHHEEECC	24.81	28152594
282	Acetylation	WEGECNGKRGHFPFT EECCCCCCCCCCCCE	41.01	26051181
304	Phosphorylation	QNPDEDFS------- CCCCCCCC-------	52.19	28985074

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
41	S	Phosphorylation	Kinase	PAK1	Q13153	PSP
221	Y	Phosphorylation	Kinase	ABL	P00519	PSP
221	Y	Phosphorylation	Kinase	ABL2	P42684	GPS
221	Y	Phosphorylation	Kinase	ABL-FAMILY	-	GPS
239	Y	Phosphorylation	Kinase	ABL1	P00519	GPS
251	Y	Phosphorylation	Kinase	ABL1	P00519	GPS
251	Y	Phosphorylation	Kinase	ABL-FAMILY	-	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CRK_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CRK_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PLS1_HUMAN	PLSCR1	physical	16189514
DPPA4_HUMAN	DPPA4	physical	16189514
PRS10_HUMAN	PSMC6	physical	16189514
RHG32_HUMAN	ARHGAP32	physical	12819203
DOCK1_HUMAN	DOCK1	physical	12615911
BCAR1_HUMAN	BCAR1	physical	12615911
SRC_HUMAN	SRC	physical	12615911
M4K1_HUMAN	MAP4K1	physical	9788432
EPHA3_HUMAN	EPHA3	physical	11870224
SH3K1_HUMAN	SH3KBP1	physical	11071869
SOCS1_HUMAN	SOCS1	physical	10022833
DOCK1_HUMAN	DOCK1	physical	10559471
DOCK1_HUMAN	DOCK1	physical	8657152
IRS4_HUMAN	IRS4	physical	11316748
DOCK1_HUMAN	DOCK1	physical	11369773
BCAR1_HUMAN	BCAR1	physical	11369773
BCAR1_HUMAN	BCAR1	physical	9920935
ASAP1_HUMAN	ASAP1	physical	9819391
EGFR_HUMAN	EGFR	physical	9642287
AVIL_HUMAN	AVIL	physical	11287316
GRB2_HUMAN	GRB2	physical	10970810
DOCK1_HUMAN	DOCK1	physical	8662907
GRB2_HUMAN	GRB2	physical	8662907
RET_HUMAN	RET	physical	9393871
BCAR1_HUMAN	BCAR1	physical	10085298
FAK1_HUMAN	PTK2	physical	10085298
PAXI_HUMAN	PXN	physical	10085298
PGFRA_HUMAN	PDGFRA	physical	10733900
PGFRB_HUMAN	PDGFRB	physical	10733900
IRS4_HUMAN	IRS4	physical	9614078
EPHB3_HUMAN	EPHB3	physical	9674711
FRS2_HUMAN	FRS2	physical	10092678
EPHB2_HUMAN	EPHB2	physical	10644995
RPGF1_HUMAN	RAPGEF1	physical	7512734
SOS1_HUMAN	SOS1	physical	8810325
GRB2_HUMAN	GRB2	physical	8810325
PAXI_HUMAN	PXN	physical	12198159
XPO1_HUMAN	XPO1	physical	11839808
WEE1_HUMAN	WEE1	physical	11839808
CASL_HUMAN	NEDD9	physical	9497377
SHB_HUMAN	SHB	physical	10964504
ZAP70_HUMAN	ZAP70	physical	10419455
BCAR1_HUMAN	BCAR1	physical	9581808
CBL_HUMAN	CBL	physical	9461587
CBL_HUMAN	CBL	physical	9178909
PTN1_HUMAN	PTPN1	physical	8940134
M4K1_HUMAN	MAP4K1	physical	9891069
MICA1_HUMAN	MICAL1	physical	11827972
M4K1_HUMAN	MAP4K1	physical	11279207
BCAR1_HUMAN	BCAR1	physical	10753828
DOCK1_HUMAN	DOCK1	physical	15673687
BCAR1_HUMAN	BCAR1	physical	15673687
BCR_HUMAN	BCR	physical	8943292
XPO2_HUMAN	CSE1L	physical	8943292
CBL_HUMAN	CBL	physical	8943292
SOS1_HUMAN	SOS1	physical	8943292
RPGF1_HUMAN	RAPGEF1	physical	8943292
P85A_HUMAN	PIK3R1	physical	11418612
CBL_HUMAN	CBL	physical	10962563
GRB2_HUMAN	GRB2	physical	10962563
SRC_HUMAN	SRC	physical	10962563
P85A_HUMAN	PIK3R1	physical	10962563
CBL_HUMAN	CBL	physical	9129019
CBL_HUMAN	CBL	physical	8626404
BCAR1_HUMAN	BCAR1	physical	17038317
CBL_HUMAN	CBL	physical	8683103
CBL_HUMAN	CBL	physical	9416834
CASL_HUMAN	NEDD9	physical	9295052
CBL_HUMAN	CBL	physical	8524328
CBL_HUMAN	CBL	physical	8626543
RPGF1_HUMAN	RAPGEF1	physical	7531694
SOS1_HUMAN	SOS1	physical	19380743
ABL1_HUMAN	ABL1	physical	19380743
BCR_HUMAN	BCR	physical	19380743
PK3CB_HUMAN	PIK3CB	physical	19380743
RPGF1_HUMAN	RAPGEF1	physical	19380743
P85B_HUMAN	PIK3R2	physical	19380743
K2C1_HUMAN	KRT1	physical	19380743
ASAP1_HUMAN	ASAP1	physical	19380743
P85A_HUMAN	PIK3R1	physical	19380743
PK3CA_HUMAN	PIK3CA	physical	19380743
K22E_HUMAN	KRT2	physical	19380743
K1C9_HUMAN	KRT9	physical	19380743
K1C10_HUMAN	KRT10	physical	19380743
HSP7C_HUMAN	HSPA8	physical	19380743
K1C14_HUMAN	KRT14	physical	19380743
CBL_HUMAN	CBL	physical	19380743
K2C5_HUMAN	KRT5	physical	19380743
K1C16_HUMAN	KRT16	physical	19380743
K2C6A_HUMAN	KRT6A	physical	19380743
K2C6B_HUMAN	KRT6B	physical	19380743
P3C2B_HUMAN	PIK3C2B	physical	19380743
TBB5_HUMAN	TUBB	physical	19380743
TBB4B_HUMAN	TUBB4B	physical	19380743
CASS4_HUMAN	CASS4	physical	19380743
PTN11_HUMAN	PTPN11	physical	19380743
SHIP2_HUMAN	INPPL1	physical	19380743
K1C17_HUMAN	KRT17	physical	19380743
ACTB_HUMAN	ACTB	physical	19380743
TBB2A_HUMAN	TUBB2A	physical	19380743
SOS2_HUMAN	SOS2	physical	19380743
SPN90_HUMAN	NCKIPSD	physical	19380743
EDC4_HUMAN	EDC4	physical	19380743
GRB2_HUMAN	GRB2	physical	19380743
HS71L_HUMAN	HSPA1L	physical	19380743
TBB3_HUMAN	TUBB3	physical	19380743
TBA1A_HUMAN	TUBA1A	physical	19380743
UBS3B_HUMAN	UBASH3B	physical	19380743
CBLB_HUMAN	CBLB	physical	19380743
ABL2_HUMAN	ABL2	physical	19380743
GRP75_HUMAN	HSPA9	physical	19380743
RS19_HUMAN	RPS19	physical	19380743
P55G_HUMAN	PIK3R3	physical	19380743
PEAK1_HUMAN	PEAK1	physical	19380743
GAB2_HUMAN	GAB2	physical	19380743
HSP76_HUMAN	HSPA6	physical	19380743
K2C3_HUMAN	KRT3	physical	19380743
K1C19_HUMAN	KRT19	physical	19380743
EPS15_HUMAN	EPS15	physical	19380743
K1C15_HUMAN	KRT15	physical	19380743
BCAR1_HUMAN	BCAR1	physical	19380743
GRP78_HUMAN	HSPA5	physical	19380743
AP2A1_HUMAN	AP2A1	physical	19380743
M4K5_HUMAN	MAP4K5	physical	19380743
K22O_HUMAN	KRT76	physical	19380743
K2C1B_HUMAN	KRT77	physical	19380743
PK3CD_HUMAN	PIK3CD	physical	19380743
GAB1_HUMAN	GAB1	physical	19380743
K2C73_HUMAN	KRT73	physical	19380743
K2C8_HUMAN	KRT8	physical	19380743
AGO2_HUMAN	AGO2	physical	19380743
1433G_HUMAN	YWHAG	physical	19380743
K2C79_HUMAN	KRT79	physical	19380743
K2C78_HUMAN	KRT78	physical	19380743
SHC1_HUMAN	SHC1	physical	19380743
UBC_HUMAN	UBC	physical	19380743
EF1A1_HUMAN	EEF1A1	physical	19380743
1433T_HUMAN	YWHAQ	physical	19380743
COR1C_HUMAN	CORO1C	physical	19380743
AP2B1_HUMAN	AP2B1	physical	19380743
RS5_HUMAN	RPS5	physical	19380743
DDX3X_HUMAN	DDX3X	physical	19380743
DDX6_HUMAN	DDX6	physical	19380743
UBS3A_HUMAN	UBASH3A	physical	19380743
K1C24_HUMAN	KRT24	physical	19380743
RS25_HUMAN	RPS25	physical	19380743
1433S_HUMAN	SFN	physical	19380743
ASAP3_HUMAN	ASAP3	physical	19380743
K1C12_HUMAN	KRT12	physical	19380743
AGO1_HUMAN	AGO1	physical	19380743
DNJA3_HUMAN	DNAJA3	physical	19380743
MCE1_HUMAN	RNGTT	physical	19380743
RL23_HUMAN	RPL23	physical	19380743
HS90B_HUMAN	HSP90AB1	physical	19380743
LYSC_HUMAN	LYZ	physical	19380743
DDX5_HUMAN	DDX5	physical	19380743
RS3_HUMAN	RPS3	physical	19380743
SPB6_HUMAN	SERPINB6	physical	19380743
HPBP1_HUMAN	HSPBP1	physical	19380743
DSC1_HUMAN	DSC1	physical	19380743
GGA3_HUMAN	GGA3	physical	21664574
BCAR1_HUMAN	BCAR1	physical	11839772
BCAR1_HUMAN	BCAR1	physical	11278916
FUBP1_HUMAN	FUBP1	physical	22939629
PUR9_HUMAN	ATIC	physical	22939629
SERPH_HUMAN	SERPINH1	physical	22939629
SIAS_HUMAN	NANS	physical	22939629
DHX9_HUMAN	DHX9	physical	22939629
HSPB1_HUMAN	HSPB1	physical	22939629
SPRE_HUMAN	SPR	physical	22939629
CBL_HUMAN	CBL	physical	8662998
LIPB2_HUMAN	PPFIBP2	physical	19447967
PTN4_HUMAN	PTPN4	physical	21988832
MK04_HUMAN	MAPK4	physical	21988832
CBL_HUMAN	CBL	physical	11792427
SPR2A_HUMAN	SPRR2A	physical	18155796
SAXO1_HUMAN	FAM154A	physical	25416956
BEX5_HUMAN	BEX5	physical	25814554
RTCB_HUMAN	RTCB	physical	25814554
CBLC_HUMAN	CBLC	physical	25814554
CTF18_HUMAN	CHTF18	physical	25814554
CNDP2_HUMAN	CNDP2	physical	25814554
DOK2_HUMAN	DOK2	physical	25814554
DOK3_HUMAN	DOK3	physical	25814554
DOK7_HUMAN	DOK7	physical	25814554
ELK1_HUMAN	ELK1	physical	25814554
EPYC_HUMAN	EPYC	physical	25814554
EYA3_HUMAN	EYA3	physical	25814554
GARE1_HUMAN	GAREM	physical	25814554
FSTL1_HUMAN	FSTL1	physical	25814554
GABP2_HUMAN	GABPB2	physical	25814554
HSH2D_HUMAN	HSH2D	physical	25814554
BACD1_HUMAN	KCTD13	physical	25814554
KLH20_HUMAN	KLHL20	physical	25814554
LASP1_HUMAN	LASP1	physical	25814554
MAGC3_HUMAN	MAGEC3	physical	25814554
3MG_HUMAN	MPG	physical	25814554
MYLIP_HUMAN	MYLIP	physical	25814554
MYOZ2_HUMAN	MYOZ2	physical	25814554
NUFP2_HUMAN	NUFIP2	physical	25814554
PA1B2_HUMAN	PAFAH1B2	physical	25814554
PHC2_HUMAN	PHC2	physical	25814554
P85A_HUMAN	PIK3R1	physical	25814554
P85B_HUMAN	PIK3R2	physical	25814554
P55G_HUMAN	PIK3R3	physical	25814554
KAPCA_HUMAN	PRKACA	physical	25814554
TMG2_HUMAN	PRRG2	physical	25814554
FAK1_HUMAN	PTK2	physical	25814554
RAB2B_HUMAN	RAB2B	physical	25814554
SEM4D_HUMAN	SEMA4D	physical	25814554
SH22A_HUMAN	SH2D2A	physical	25814554
SOCS1_HUMAN	SOCS1	physical	25814554
SOCS6_HUMAN	SOCS6	physical	25814554
STAT4_HUMAN	STAT4	physical	25814554
TELT_HUMAN	TCAP	physical	25814554
T4S19_HUMAN	TM4SF19	physical	25814554
VAC14_HUMAN	VAC14	physical	25814554
CBLB_HUMAN	CBLB	physical	25814554
ABL2_HUMAN	ABL2	physical	25814554
CBL_HUMAN	CBL	physical	25814554
ANKZ1_HUMAN	ANKZF1	physical	25814554
ANLN_HUMAN	ANLN	physical	25814554
ASB9_HUMAN	ASB9	physical	25814554
ASCL4_HUMAN	ASCL4	physical	25814554
PRC2B_HUMAN	PRRC2B	physical	25814554
BATF3_HUMAN	BATF3	physical	25814554
CD017_HUMAN	C4orf17	physical	25814554
SETD9_HUMAN	SETD9	physical	25814554
CF141_HUMAN	C6orf141	physical	25814554
CORO6_HUMAN	CORO6	physical	25814554
ESTD_HUMAN	ESD	physical	25814554
HABP4_HUMAN	HABP4	physical	25814554
IF140_HUMAN	IFT140	physical	25814554
IN80E_HUMAN	INO80E	physical	25814554
ISL1_HUMAN	ISL1	physical	25814554
KCD17_HUMAN	KCTD17	physical	25814554
KLF15_HUMAN	KLF15	physical	25814554
LHX8_HUMAN	LHX8	physical	25814554
MNDA_HUMAN	MNDA	physical	25814554
PRS4_HUMAN	PSMC1	physical	25814554
PTTG1_HUMAN	PTTG1	physical	25814554
RYBP_HUMAN	RYBP	physical	25814554
SEPT6_HUMAN	SEPT6	physical	25814554
STRN4_HUMAN	STRN4	physical	25814554
TDG_HUMAN	TDG	physical	25814554
P53_HUMAN	TP53	physical	25814554
TBA1C_HUMAN	TUBA1C	physical	25814554
TWST2_HUMAN	TWIST2	physical	25814554
WDR83_HUMAN	WDR83	physical	25814554
ZKSC7_HUMAN	ZKSCAN7	physical	25814554
ZN557_HUMAN	ZNF557	physical	25814554
ATF3_HUMAN	ATF3	physical	25814554
COX6C_HUMAN	COX6C	physical	26496610
H13_HUMAN	HIST1H1D	physical	26496610
MYPT1_HUMAN	PPP1R12A	physical	26496610
NUMA1_HUMAN	NUMA1	physical	26496610
KAT6A_HUMAN	KAT6A	physical	26496610
MPDZ_HUMAN	MPDZ	physical	26496610
ARC1B_HUMAN	ARPC1B	physical	26496610
CMC2_HUMAN	SLC25A13	physical	26496610
LCOR_HUMAN	C10orf12	physical	26496610
RM48_HUMAN	MRPL48	physical	26496610
INF2_HUMAN	INF2	physical	26496610
FLNA_HUMAN	FLNA	physical	25241761
SOS1_HUMAN	SOS1	physical	25241761
P85A_HUMAN	PIK3R1	physical	25241761
STA5A_HUMAN	STAT5A	physical	25241761
FGFR1_HUMAN	FGFR1	physical	25241761
MK08_HUMAN	MAPK8	physical	25241761
PGFRA_HUMAN	PDGFRA	physical	25241761
RET_HUMAN	RET	physical	25241761
FGFR1_HUMAN	FGFR1	physical	10464310
SHC1_HUMAN	SHC1	physical	10464310
BCAR1_HUMAN	BCAR1	physical	10464310
RPGF1_HUMAN	RAPGEF1	physical	10464310
PTN11_HUMAN	PTPN11	physical	10464310

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CRK_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, AND MASS SPECTROMETRY.	19413330 [Abstract]
Phosphorylation
Reference	PubMed
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-74 AND SER-83, AND MASSSPECTROMETRY.	18669648 [Abstract]
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