K1C24_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: K1C24_HUMAN
• UniProt AC: Q2M2I5
• Protein Name: Keratin, type I cytoskeletal 24
• Gene Name: KRT24
• Organism: Homo sapiens (Human).
• Sequence Length: 525
• Protein Sequence: MSCSSRASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQVSSISEVKVK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MSCSSRASSSRAGGS CCCCCCCCCCCCCCC	27.95	-
17	Phosphorylation	SRAGGSSSARVSAGG CCCCCCCCCEEECCC	23.07	22964224
25	Phosphorylation	ARVSAGGSSFSSGSR CEEECCCCCCCCCCC	27.56	27251275
26	Phosphorylation	RVSAGGSSFSSGSRC EEECCCCCCCCCCCC	32.21	28348404
28	Phosphorylation	SAGGSSFSSGSRCGL ECCCCCCCCCCCCCC	35.42	28348404
29	Phosphorylation	AGGSSFSSGSRCGLG CCCCCCCCCCCCCCC	38.48	28348404
31	Phosphorylation	GSSFSSGSRCGLGGS CCCCCCCCCCCCCCC	26.75	28348404
113	Phosphorylation	CGSSRFSSGATGGFY CCCCCCCCCCCCCCC	29.72	25954137
120	Phosphorylation	SGATGGFYSYGGGMG CCCCCCCCCCCCCCC	12.31	25954137
121	Phosphorylation	GATGGFYSYGGGMGG CCCCCCCCCCCCCCC	18.29	25954137
122	Phosphorylation	ATGGFYSYGGGMGGG CCCCCCCCCCCCCCC	14.38	-
137	Phosphorylation	VGDGGLFSGGEKQTM CCCCCCCCCCCHHHH	51.43	25954137
143	Phosphorylation	FSGGEKQTMQNLNDR CCCCCHHHHHHHHHH	31.62	20860994
154	Phosphorylation	LNDRLANYLDKVRAL HHHHHHHHHHHHHHH	15.63	22461510
193	Phosphorylation	GGSGRDYSKYYSIIE CCCCCCHHHHHHHHH	20.62	21712546
195	Phosphorylation	SGRDYSKYYSIIEDL CCCCHHHHHHHHHHH	9.12	21712546
197	Phosphorylation	RDYSKYYSIIEDLRN CCHHHHHHHHHHHHH	17.63	21712546
261	Phosphorylation	VLDDLTMTRSDLEMQ HHHHHCCCHHHHHHH	23.06	18452278
299	Phosphorylation	GSSGGEVTVEMNAAP CCCCCEEEEEEECCC	13.37	23532336
348	Phosphorylation	ASLQAQISTDAGAAT HHHHHHHHCCCCCCH	14.25	27251275
349	Phosphorylation	SLQAQISTDAGAATS HHHHHHHCCCCCCHH	31.34	27251275
362	Phosphorylation	TSAKNEITELKRTLQ HHHHHHHHHHHHHHH	29.14	23403867
487	Phosphorylation	DSRSGSCSGQGRDSS CCCCCCCCCCCCCCC	35.53	-
494	Phosphorylation	SGQGRDSSKTRVTKT CCCCCCCCCCEEEEH	42.19	-
517	Phosphorylation	KVVSSQVSSISEVKV EEEECCCCCCCEEEC	17.83	27251275
518	Phosphorylation	VVSSQVSSISEVKVK EEECCCCCCCEEECC	31.14	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of K1C24_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of K1C24_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of K1C24_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of K1C24_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.