| UniProt ID | LHX8_HUMAN | |
|---|---|---|
| UniProt AC | Q68G74 | |
| Protein Name | LIM/homeobox protein Lhx8 | |
| Gene Name | LHX8 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 356 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Transcription factor involved in differentiation of certain neurons and mesenchymal cells.. | |
| Protein Sequence | MQILSRCQGLMSEECGRTTALAAGRTRKGAGEEGLVSPEGAGDEDSCSSSAPLSPSSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAVPPSRLSPPMLEEMAYSAYVPQDGTMLTALHSYMDAHSPTTLGLQPLLPHSMTQLPISHT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 56 | Phosphorylation | SSAPLSPSSSPRSMA CCCCCCCCCCCCHHC | 39.82 | 24719451 | |
| 57 | Phosphorylation | SAPLSPSSSPRSMAS CCCCCCCCCCCHHCC | 47.98 | 29802988 | |
| 116 | Phosphorylation | LGRHTSCYIKDKDIF CCCCCCEEECCCCEE | 15.69 | 22817900 | |
| 285 | Phosphorylation | ARHKKHVSPNHSSST HHHHHCCCCCCCCCC | 21.50 | 26270265 | |
| 289 | Phosphorylation | KHVSPNHSSSTPVTA HCCCCCCCCCCCCCC | 32.40 | 26270265 | |
| 290 | Phosphorylation | HVSPNHSSSTPVTAV CCCCCCCCCCCCCCC | 30.58 | 26270265 | |
| 291 | Phosphorylation | VSPNHSSSTPVTAVP CCCCCCCCCCCCCCC | 39.48 | 26270265 | |
| 292 | Phosphorylation | SPNHSSSTPVTAVPP CCCCCCCCCCCCCCH | 24.59 | 26270265 | |
| 295 | Phosphorylation | HSSSTPVTAVPPSRL CCCCCCCCCCCHHHC | 24.12 | 26270265 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of LHX8_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of LHX8_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of LHX8_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SUV91_HUMAN | SUV39H1 | physical | 23455924 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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