EGFR_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EGFR_HUMAN
• UniProt AC: P00533
• Protein Name: Epidermal growth factor receptor
• Gene Name: EGFR
• Organism: Homo sapiens (Human).
• Sequence Length: 1210
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Endosome . En
• Protein Description: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. [PubMed: 2790960]
• Protein Sequence: MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Sumoylation	VCQGTSNKLTQLGTF CCCCCCCHHHHCCHH	53.32	-
37	Sumoylation	VCQGTSNKLTQLGTF CCCCCCCHHHHCCHH	53.32	-
50	Phosphorylation	TFEDHFLSLQRMFNN HHHHHHHHHHHHHCC	22.85	24719451
56 (in isoform 1)	N-linked_Glycosylation	-	42.79	-
56	N-linked_Glycosylation	LSLQRMFNNCEVVLG HHHHHHHCCCEEEEC	42.79	12731890
56	N-linked_Glycosylation	LSLQRMFNNCEVVLG HHHHHHHCCCEEEEC	42.79	16799092
56 (in isoform 2)	N-linked_Glycosylation	-	42.79	-
56 (in isoform 3)	N-linked_Glycosylation	-	42.79	-
73	N-linked_Glycosylation	EITYVQRNYDLSFLK EEEEEECCCCHHHHH	19.99	20837704
77	Phosphorylation	VQRNYDLSFLKTIQE EECCCCHHHHHHHHH	26.15	21712546
111	Sulfoxidation	LQIIRGNMYYENSYA CEEEECCCCCCCCEE	4.14	28465586
112	Phosphorylation	QIIRGNMYYENSYAL EEEECCCCCCCCEEE	16.18	-
113	Phosphorylation	IIRGNMYYENSYALA EEECCCCCCCCEEEE	9.62	-
117	Phosphorylation	NMYYENSYALAVLSN CCCCCCCEEEEEHHC	19.74	-
128 (in isoform 1)	N-linked_Glycosylation	-	39.25	-
128	N-linked_Glycosylation	VLSNYDANKTGLKEL EHHCCCCCCCCCCCC	39.25	12731890
128	N-linked_Glycosylation	VLSNYDANKTGLKEL EHHCCCCCCCCCCCC	39.25	12731890
128 (in isoform 2)	N-linked_Glycosylation	-	39.25	-
128 (in isoform 3)	N-linked_Glycosylation	-	39.25	-
133	Acetylation	DANKTGLKELPMRNL CCCCCCCCCCCCCCH	59.56	18530309
151	Phosphorylation	LHGAVRFSNNPALCN HHHHHHCCCCCCCCC	25.74	21080693
175 (in isoform 1)	N-linked_Glycosylation	-	28.79	-
175	N-linked_Glycosylation	VSSDFLSNMSMDFQN HCHHHHHHCCCCHHH	28.79	12731890
175	N-linked_Glycosylation	VSSDFLSNMSMDFQN HCHHHHHHCCCCHHH	28.79	12731890
175 (in isoform 2)	N-linked_Glycosylation	-	28.79	-
175 (in isoform 3)	N-linked_Glycosylation	-	28.79	-
190	S-nitrosocysteine	HLGSCQKCDPSCPNG CCCCCCCCCCCCCCC	3.71	-
190	S-nitrosylation	HLGSCQKCDPSCPNG CCCCCCCCCCCCCCC	3.71	22178444
196 (in isoform 1)	N-linked_Glycosylation	-	60.38	-
196	N-linked_Glycosylation	KCDPSCPNGSCWGAG CCCCCCCCCCCCCCC	60.38	12731890
196	N-linked_Glycosylation	KCDPSCPNGSCWGAG CCCCCCCCCCCCCCC	60.38	12731890
196 (in isoform 2)	N-linked_Glycosylation	-	60.38	-
196 (in isoform 3)	N-linked_Glycosylation	-	60.38	-
212	Acetylation	ENCQKLTKIICAQQC HHHHHHHHHHHHHHC	40.28	26051181
212	Ubiquitination	ENCQKLTKIICAQQC HHHHHHHHHHHHHHC	40.28	-
222	Dimethylation	CAQQCSGRCRGKSPS HHHHCCCCCCCCCHH	7.23	-
222	Methylation	CAQQCSGRCRGKSPS HHHHCCCCCCCCCHH	7.23	-
224	Dimethylation	QQCSGRCRGKSPSDC HHCCCCCCCCCHHHC	54.97	-
224	Methylation	QQCSGRCRGKSPSDC HHCCCCCCCCCHHHC	54.97	-
227	Phosphorylation	SGRCRGKSPSDCCHN CCCCCCCCHHHCCCC	32.24	30576142
229	Phosphorylation	RCRGKSPSDCCHNQC CCCCCCHHHCCCCCC	50.82	21487020
246	Phosphorylation	GCTGPRESDCLVCRK CCCCCCCCCEEEECC	34.60	30576142
268	Sulfoxidation	KDTCPPLMLYNPTTY CCCCCCEEEECCCEE	4.62	28465586
277	Sulfoxidation	YNPTTYQMDVNPEGK ECCCEEEECCCCCCC	4.35	28465586
284	Acetylation	MDVNPEGKYSFGATC ECCCCCCCCEEECEE	35.74	12650313
290 (in isoform 1)	Phosphorylation	-	20.43	-
290	Phosphorylation	GKYSFGATCVKKCPR CCCEEECEEEECCCC	20.43	18452278
290 (in isoform 2)	Phosphorylation	-	20.43	-
290 (in isoform 3)	Phosphorylation	-	20.43	-
291	S-nitrosocysteine	KYSFGATCVKKCPRN CCEEECEEEECCCCC	4.13	-
291	S-nitrosylation	KYSFGATCVKKCPRN CCEEECEEEECCCCC	4.13	22178444
293	Ubiquitination	SFGATCVKKCPRNYV EEECEEEECCCCCEE	51.29	-
311	S-nitrosocysteine	HGSCVRACGADSYEM CCHHHHCCCCCCEEC	3.02	-
311	S-nitrosylation	HGSCVRACGADSYEM CCHHHHCCCCCCEEC	3.02	22178444
318	Sulfoxidation	CGADSYEMEEDGVRK CCCCCEECHHHCCCC	5.33	28465586
329	S-nitrosocysteine	GVRKCKKCEGPCRKV CCCCCCCCCCCHHHC	4.46	-
329	S-nitrosylation	GVRKCKKCEGPCRKV CCCCCCCCCCCHHHC	4.46	22178444
346	Acetylation	GIGIGEFKDSLSINA CCCCCCCCCCEECCC	41.95	132865
352 (in isoform 1)	N-linked_Glycosylation	-	37.02	-
352	N-linked_Glycosylation	FKDSLSINATNIKHF CCCCEECCCCCCCCC	37.02	12297049
352	N-linked_Glycosylation	FKDSLSINATNIKHF CCCCEECCCCCCCCC	37.02	12297049
352 (in isoform 2)	N-linked_Glycosylation	-	37.02	-
352 (in isoform 3)	N-linked_Glycosylation	-	37.02	-
354	Phosphorylation	DSLSINATNIKHFKN CCEECCCCCCCCCCC	32.75	24719451
361 (in isoform 1)	N-linked_Glycosylation	-	33.10	-
361	N-linked_Glycosylation	TNIKHFKNCTSISGD CCCCCCCCCCEECCC	33.10	12731890
361	N-linked_Glycosylation	TNIKHFKNCTSISGD CCCCCCCCCCEECCC	33.10	12731890
361 (in isoform 2)	N-linked_Glycosylation	-	33.10	-
361 (in isoform 3)	N-linked_Glycosylation	-	33.10	-
380	O-linked_Glycosylation	PVAFRGDSFTHTPPL EEEECCCCCCCCCCC	34.56	30059200
396	2-Hydroxyisobutyrylation	PQELDILKTVKEITG HHHCHHHHHHHHHHC	52.16	-
396	Ubiquitination	PQELDILKTVKEITG HHHCHHHHHHHHHHC	52.16	-
413 (in isoform 1)	N-linked_Glycosylation	-	48.34	-
413	N-linked_Glycosylation	LIQAWPENRTDLHAF HEEECCCCCCCCHHH	48.34	12731890
413	N-linked_Glycosylation	LIQAWPENRTDLHAF HEEECCCCCCCCHHH	48.34	12731890
413 (in isoform 3)	N-linked_Glycosylation	-	48.34	-
444 (in isoform 1)	N-linked_Glycosylation	-	28.17	-
444	N-linked_Glycosylation	SLAVVSLNITSLGLR EEEEEEECCCHHHCC	28.17	12731890
444	N-linked_Glycosylation	SLAVVSLNITSLGLR EEEEEEECCCHHHCC	28.17	12731890
444 (in isoform 3)	N-linked_Glycosylation	-	28.17	-
457	Phosphorylation	LRSLKEISDGDVIIS CCCCHHCCCCCEEEE	36.31	-
470	S-nitrosocysteine	ISGNKNLCYANTINW EECCCCCEEECCCCH	4.16	-
470	S-nitrosylation	ISGNKNLCYANTINW EECCCCCEEECCCCH	4.16	22178444
479	Ubiquitination	ANTINWKKLFGTSGQ ECCCCHHHHHCCCCC	40.43	-
487	Ubiquitination	LFGTSGQKTKIISNR HHCCCCCCEEEEECC	56.14	-
489	Ubiquitination	GTSGQKTKIISNRGE CCCCCCEEEEECCCC	45.11	-
511	Phosphorylation	QVCHALCSPEGCWGP CHHHHHCCCCCCCCC	27.17	21080693
528 (in isoform 1)	N-linked_Glycosylation	-	40.21	-
528	N-linked_Glycosylation	RDCVSCRNVSRGREC CCCCCCCCCCCCCHH	40.21	12731890
528	N-linked_Glycosylation	RDCVSCRNVSRGREC CCCCCCCCCCCCCHH	40.21	12731890
528 (in isoform 3)	N-linked_Glycosylation	-	40.21	-
538	Ubiquitination	RGRECVDKCNLLEGE CCCHHHHHCCCCCCC	12.48	-
568 (in isoform 1)	N-linked_Glycosylation	-	29.45	-
568	N-linked_Glycosylation	ECLPQAMNITCTGRG HHHCCCCCEEECCCC	29.45	12731890
568	N-linked_Glycosylation	ECLPQAMNITCTGRG HHHCCCCCEEECCCC	29.45	12731890
568 (in isoform 3)	N-linked_Glycosylation	-	29.45	-
585	Phosphorylation	NCIQCAHYIDGPHCV CCEEECCCCCCCCEE	5.12	21080693
603 (in isoform 1)	N-linked_Glycosylation	-	40.85	-
603	N-linked_Glycosylation	PAGVMGENNTLVWKY CCCCCCCCCEEEEEE	40.85	12731890
603	N-linked_Glycosylation	PAGVMGENNTLVWKY CCCCCCCCCEEEEEE	40.85	12731890
603 (in isoform 3)	N-linked_Glycosylation	-	40.85	-
623 (in isoform 1)	N-linked_Glycosylation	-	13.70	-
623	N-linked_Glycosylation	VCHLCHPNCTYGCTG CEEECCCCCCCCCCC	13.70	12731890
623	N-linked_Glycosylation	VCHLCHPNCTYGCTG CEEECCCCCCCCCCC	13.70	16799092
623 (in isoform 3)	N-linked_Glycosylation	-	13.70	-
645	Phosphorylation	TNGPKIPSIATGMVG CCCCCCCHHHHHHHH	28.47	-
648	Phosphorylation	PKIPSIATGMVGALL CCCCHHHHHHHHHHH	24.92	-
678	Phosphorylation	RHIVRKRTLRRLLQE HHHHHHHHHHHHHHH	27.87	10523301
693	Phosphorylation	RELVEPLTPSGEAPN CCCCCCCCCCCCCCC	26.56	22167270
695	Phosphorylation	LVEPLTPSGEAPNQA CCCCCCCCCCCCCHH	43.99	22167270
708	Acetylation	QALLRILKETEFKKI HHHHHHHHHCCCCEE	61.28	21094134
708	Ubiquitination	QALLRILKETEFKKI HHHHHHHHHCCCCEE	61.28	17940017
713	Ubiquitination	ILKETEFKKIKVLGS HHHHCCCCEEEEECC	47.56	16543144
714	Ubiquitination	LKETEFKKIKVLGSG HHHCCCCEEEEECCC	53.75	16543144
716	Ubiquitination	ETEFKKIKVLGSGAF HCCCCEEEEECCCCC	40.04	16543144
720	Phosphorylation	KKIKVLGSGAFGTVY CEEEEECCCCCCCEE	23.84	21945579
725	Phosphorylation	LGSGAFGTVYKGLWI ECCCCCCCEECCEEC	17.76	21945579
727	Phosphorylation	SGAFGTVYKGLWIPE CCCCCCEECCEECCC	10.12	16729043
728	Ubiquitination	GAFGTVYKGLWIPEG CCCCCEECCEECCCC	43.10	17940017
737	Ubiquitination	LWIPEGEKVKIPVAI EECCCCCEEECCHHH	60.74	16543144
737 (in isoform 1)	Ubiquitination	-	60.74	21890473
739	2-Hydroxyisobutyrylation	IPEGEKVKIPVAIKE CCCCCEEECCHHHHH	52.97	-
739	Ubiquitination	IPEGEKVKIPVAIKE CCCCCEEECCHHHHH	52.97	17940017
745	2-Hydroxyisobutyrylation	VKIPVAIKELREATS EECCHHHHHHHHCCC	40.74	-
745	Methylation	VKIPVAIKELREATS EECCHHHHHHHHCCC	40.74	-
745	Ubiquitination	VKIPVAIKELREATS EECCHHHHHHHHCCC	40.74	-
752	Phosphorylation	KELREATSPKANKEI HHHHHCCCCCCCHHH	31.30	22817900
754	Ubiquitination	LREATSPKANKEILD HHHCCCCCCCHHHHH	65.44	16543144
757	Ubiquitination	ATSPKANKEILDEAY CCCCCCCHHHHHHHH	51.49	16543144
764	Phosphorylation	KEILDEAYVMASVDN HHHHHHHHHHHCCCC	6.68	21080693
766	Sulfoxidation	ILDEAYVMASVDNPH HHHHHHHHHCCCCHH	1.18	28465586
768	Phosphorylation	DEAYVMASVDNPHVC HHHHHHHCCCCHHHH	16.35	17653080
797	S-palmitoylation	TQLMPFGCLLDYVRE HHHCCHHHHHHHHHH	3.31	29449326
801	Phosphorylation	PFGCLLDYVREHKDN CHHHHHHHHHHCCCC	11.02	-
823	Ubiquitination	NWCVQIAKGMNYLED HHHHHHHHCCCHHHH	61.39	17940017
827	Phosphorylation	QIAKGMNYLEDRRLV HHHHCCCHHHHHCHH	11.54	21080693
846	Ubiquitination	AARNVLVKTPQHVKI HHCCCEECCCCCEEE	50.78	17940017
852	Malonylation	VKTPQHVKITDFGLA ECCCCCEEECHHHHH	37.45	26320211
852	Ubiquitination	VKTPQHVKITDFGLA ECCCCCEEECHHHHH	37.45	-
860	Acetylation	ITDFGLAKLLGAEEK ECHHHHHHHHCCHHH	49.65	21094134
860	Ubiquitination	ITDFGLAKLLGAEEK ECHHHHHHHHCCHHH	49.65	21890473
860 (in isoform 1)	Ubiquitination	-	49.65	21890473
867	2-Hydroxyisobutyrylation	KLLGAEEKEYHAEGG HHHCCHHHHHHCCCC	55.89	-
867	Acetylation	KLLGAEEKEYHAEGG HHHCCHHHHHHCCCC	55.89	21094134
867	Ubiquitination	KLLGAEEKEYHAEGG HHHCCHHHHHHCCCC	55.89	16543144
869	Phosphorylation	LGAEEKEYHAEGGKV HCCHHHHHHCCCCCC	19.87	16729043
875	Ubiquitination	EYHAEGGKVPIKWMA HHHCCCCCCCCCHHH	56.55	-
891	Phosphorylation	ESILHRIYTHQSDVW HHHHHHHHHCCHHHH	9.72	16729043
892	Phosphorylation	SILHRIYTHQSDVWS HHHHHHHHCCHHHHH	15.86	-
913	Ubiquitination	ELMTFGSKPYDGIPA HHHHCCCCCCCCCCH	48.23	17940017
915	Phosphorylation	MTFGSKPYDGIPASE HHCCCCCCCCCCHHH	30.45	16729043
925	Phosphorylation	IPASEISSILEKGER CCHHHHHHHHHCCCC	36.53	24719451
929	Ubiquitination	EISSILEKGERLPQP HHHHHHHCCCCCCCC	63.73	16543144
940	Phosphorylation	LPQPPICTIDVYMIM CCCCCCCEEEEEEEE	22.41	-
944	Phosphorylation	PICTIDVYMIMVKCW CCCEEEEEEEEEEHH	4.16	16729043
960	Ubiquitination	IDADSRPKFRELIIE CCCCCCHHHHHHHHH	56.81	17940017
970	Ubiquitination	ELIIEFSKMARDPQR HHHHHHHHHCCCCCC	41.73	16543144
978	Phosphorylation	MARDPQRYLVIQGDE HCCCCCCEEEEECCC	10.48	16729043
991	Phosphorylation	DERMHLPSPTDSNFY CCCCCCCCCCCCHHH	46.95	22167270
993	Phosphorylation	RMHLPSPTDSNFYRA CCCCCCCCCCHHHHH	57.29	21945579
995	Phosphorylation	HLPSPTDSNFYRALM CCCCCCCCHHHHHHC	31.17	21945579
998	Phosphorylation	SPTDSNFYRALMDEE CCCCCHHHHHHCCCC	10.14	16729043
1016	Dephosphorylation	DVVDADEYLIPQQGF CCCCHHHHCCCCCCC	15.52	14560030
1016	Phosphorylation	DVVDADEYLIPQQGF CCCCHHHHCCCCCCC	15.52	16729043
1025	Phosphorylation	IPQQGFFSSPSTSRT CCCCCCCCCCCCCCC	38.79	21080693
1026	Phosphorylation	PQQGFFSSPSTSRTP CCCCCCCCCCCCCCC	20.08	21080693
1028	Phosphorylation	QGFFSSPSTSRTPLL CCCCCCCCCCCCCCC	40.75	28176443
1029	Phosphorylation	GFFSSPSTSRTPLLS CCCCCCCCCCCCCCH	26.13	29116813
1030	Phosphorylation	FFSSPSTSRTPLLSS CCCCCCCCCCCCCHH	38.19	21080693
1032	Phosphorylation	SSPSTSRTPLLSSLS CCCCCCCCCCCHHHE	20.32	23663014
1036	Phosphorylation	TSRTPLLSSLSATSN CCCCCCCHHHEECCC	36.59	22617229
1037	Phosphorylation	SRTPLLSSLSATSNN CCCCCCHHHEECCCC	26.72	21080693
1039	Phosphorylation	TPLLSSLSATSNNST CCCCHHHEECCCCCC	31.30	25463755
1041	Phosphorylation	LLSSLSATSNNSTVA CCHHHEECCCCCCEE	28.72	22617229
1042	Phosphorylation	LSSLSATSNNSTVAC CHHHEECCCCCCEEE	33.46	25463755
1045	Phosphorylation	LSATSNNSTVACIDR HEECCCCCCEEEEEC	28.63	26055452
1046	Phosphorylation	SATSNNSTVACIDRN EECCCCCCEEEEECC	17.78	25463755
1049	S-palmitoylation	SNNSTVACIDRNGLQ CCCCCEEEEECCCCC	2.63	29449326
1057	Phosphorylation	IDRNGLQSCPIKEDS EECCCCCCCCCCCCC	27.23	21080693
1061	Acetylation	GLQSCPIKEDSFLQR CCCCCCCCCCCHHHH	40.38	27452117
1061	Ubiquitination	GLQSCPIKEDSFLQR CCCCCCCCCCCHHHH	40.38	-
1064	Phosphorylation	SCPIKEDSFLQRYSS CCCCCCCCHHHHHCC	29.02	25159151
1069	Phosphorylation	EDSFLQRYSSDPTGA CCCHHHHHCCCCCCC	10.28	18715874
1070	Phosphorylation	DSFLQRYSSDPTGAL CCHHHHHCCCCCCCC	30.38	3138233
1071	Phosphorylation	SFLQRYSSDPTGALT CHHHHHCCCCCCCCC	38.38	3138233
1074	Phosphorylation	QRYSSDPTGALTEDS HHHCCCCCCCCCCCC	39.83	21080693
1078	Phosphorylation	SDPTGALTEDSIDDT CCCCCCCCCCCCCCC	36.89	25159151
1081	Phosphorylation	TGALTEDSIDDTFLP CCCCCCCCCCCCCCC	22.99	21080693
1085	Phosphorylation	TEDSIDDTFLPVPEY CCCCCCCCCCCCHHH	24.27	25159151
1092	Phosphorylation	TFLPVPEYINQSVPK CCCCCHHHHCCCCCC	10.09	8408058
1096	Phosphorylation	VPEYINQSVPKRPAG CHHHHCCCCCCCCCC	35.58	28176443
1099	Ubiquitination	YINQSVPKRPAGSVQ HHCCCCCCCCCCCCC	69.71	-
1104	Phosphorylation	VPKRPAGSVQNPVYH CCCCCCCCCCCCCCC	23.72	21945579
1110	Phosphorylation	GSVQNPVYHNQPLNP CCCCCCCCCCCCCCC	9.05	16729043
1120	Phosphorylation	QPLNPAPSRDPHYQD CCCCCCCCCCCCCCC	51.96	26356563
1125	Phosphorylation	APSRDPHYQDPHSTA CCCCCCCCCCCCCCC	21.72	16729043
1130	Phosphorylation	PHYQDPHSTAVGNPE CCCCCCCCCCCCCHH	24.37	26356563
1131	Phosphorylation	HYQDPHSTAVGNPEY CCCCCCCCCCCCHHH	23.48	26356563
1138	Phosphorylation	TAVGNPEYLNTVQPT CCCCCHHHHCCCCCC	13.40	16729043
1141	Phosphorylation	GNPEYLNTVQPTCVN CCHHHHCCCCCCCCC	20.23	25106551
1145	Phosphorylation	YLNTVQPTCVNSTFD HHCCCCCCCCCCCCC	16.40	26356563
1146	S-palmitoylation	LNTVQPTCVNSTFDS HCCCCCCCCCCCCCC	3.29	29449326
1149	Phosphorylation	VQPTCVNSTFDSPAH CCCCCCCCCCCCCCH	15.28	26356563
1150	Phosphorylation	QPTCVNSTFDSPAHW CCCCCCCCCCCCCHH	26.68	26356563
1153	Phosphorylation	CVNSTFDSPAHWAQK CCCCCCCCCCHHHHC	21.57	29116813
1160	Ubiquitination	SPAHWAQKGSHQISL CCCHHHHCCCCEEEC	55.42	-
1162	Phosphorylation	AHWAQKGSHQISLDN CHHHHCCCCEEECCC	21.18	21945579
1166	Phosphorylation	QKGSHQISLDNPDYQ HCCCCEEECCCCCHH	24.09	23927012
1172	Phosphorylation	ISLDNPDYQQDFFPK EECCCCCHHCCCCCC	14.88	16729043
1179	Acetylation	YQQDFFPKEAKPNGI HHCCCCCCCCCCCCC	66.21	20513767
1179	Ubiquitination	YQQDFFPKEAKPNGI HHCCCCCCCCCCCCC	66.21	-
1182	Acetylation	DFFPKEAKPNGIFKG CCCCCCCCCCCCCCC	39.86	20513767
1182	Ubiquitination	DFFPKEAKPNGIFKG CCCCCCCCCCCCCCC	39.86	-
1188	Acetylation	AKPNGIFKGSTAENA CCCCCCCCCCCHHCC	50.46	20513767
1188	Methylation	AKPNGIFKGSTAENA CCCCCCCCCCCHHCC	50.46	-
1188	Ubiquitination	AKPNGIFKGSTAENA CCCCCCCCCCCHHCC	50.46	-
1190	Phosphorylation	PNGIFKGSTAENAEY CCCCCCCCCHHCCCE	25.65	21945579
1191	Phosphorylation	NGIFKGSTAENAEYL CCCCCCCCHHCCCEE	46.81	21945579
1197	Dephosphorylation	STAENAEYLRVAPQS CCHHCCCEEEECCCC	9.44	9733788
1197	Phosphorylation	STAENAEYLRVAPQS CCHHCCCEEEECCCC	9.44	16574647
1199	Methylation	AENAEYLRVAPQSSE HHCCCEEEECCCCCC	22.96	21258366
1204	Phosphorylation	YLRVAPQSSEFIGA- EEEECCCCCCCCCC-	30.67	21945579
1205	Phosphorylation	LRVAPQSSEFIGA-- EEECCCCCCCCCC--	31.14	21945579

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
229	S	Phosphorylation	Kinase	AKT1	P31749	PSP
229	S	Phosphorylation	Kinase	AKT2	P31751	PSP
678	T	Phosphorylation	Kinase	PKN1	Q16512	PSP
678	T	Phosphorylation	Kinase	KPCA	P17252	PhosphoELM
678	T	Phosphorylation	Kinase	PRKCA	P20444	GPS
678	T	Phosphorylation	Kinase	PKC-FAMILY	-	GPS
678	T	Phosphorylation	Kinase	PRKD1	Q15139	Uniprot
678	T	Phosphorylation	Kinase	PKC	-	Uniprot
678	T	Phosphorylation	Kinase	PKCE	Q02156	PSP
678	T	Phosphorylation	Kinase	PKC_GROUP	-	PhosphoELM
678	T	Phosphorylation	Kinase	PKN3	Q6P5Z2	PSP
693	T	Phosphorylation	Kinase	MAPK1	P28482	GPS
693	T	Phosphorylation	Kinase	PRKD1	Q15139	Uniprot
693	T	Phosphorylation	Kinase	MAPK3	P27361	GPS
693	T	Phosphorylation	Kinase	MAPK14	Q16539	GPS
693	T	Phosphorylation	Kinase	P38-SUBFAMILY	-	GPS
693	T	Phosphorylation	Kinase	PKG2	Q13237	PSP
727	Y	Phosphorylation	Kinase	SRC	P12931	PSP
764	Y	Phosphorylation	Kinase	SRC	P12931	PSP
768	S	Phosphorylation	Kinase	CAMK2A	P11275	PSP
768	S	Phosphorylation	Kinase	CAMK2-FAMILY	-	GPS
768	S	Phosphorylation	Kinase	KCC2A	Q9UQM7	PhosphoELM
869	Y	Phosphorylation	Kinase	SRC	P12931	PSP
869	Y	Phosphorylation	Kinase	SRC	P05480	PSP
869	Y	Phosphorylation	Kinase	EGFR	P00533	PSP
869	Y	Phosphorylation	Kinase	SRC64	-	PhosphoELM
892	T	Phosphorylation	Kinase	PRKAA1	Q13131	GPS
915	Y	Phosphorylation	Kinase	SRC	P12931	PSP
915	Y	Phosphorylation	Kinase	SRC64	-	PhosphoELM
944	Y	Phosphorylation	Kinase	SRC	P12931	PSP
944	Y	Phosphorylation	Kinase	SRC64	-	PhosphoELM
998	Y	Phosphorylation	Kinase	EGFR	P00533	GPS
1016	Y	Phosphorylation	Kinase	ABL1	P00519	GPS
1016	Y	Phosphorylation	Kinase	SRC64	-	PhosphoELM
1016	Y	Phosphorylation	Kinase	SRC	P12931	PSP
1016	Y	Phosphorylation	Kinase	EGFR	P00533	PSP
1026	S	Phosphorylation	Kinase	CDK1	P06493	PSP
1039	S	Phosphorylation	Kinase	MAPK11	Q15759	GPS
1039	S	Phosphorylation	Kinase	MAPK14	Q16539	GPS
1041	T	Phosphorylation	Kinase	MAPK11	Q15759	GPS
1041	T	Phosphorylation	Kinase	MAPK14	Q16539	GPS
1070	S	Phosphorylation	Kinase	CAMK2-FAMILY	-	GPS
1070	S	Phosphorylation	Kinase	KCC2A	Q9UQM7	PhosphoELM
1070	S	Phosphorylation	Kinase	CAMK2A	P11275	PSP
1071	S	Phosphorylation	Kinase	CAMK2-FAMILY	-	GPS
1071	S	Phosphorylation	Kinase	KCC2A	Q9UQM7	PhosphoELM
1071	S	Phosphorylation	Kinase	CAMK2A	P11275	PSP
1081	S	Phosphorylation	Kinase	CAMK2A	P11275	PSP
1081	S	Phosphorylation	Kinase	CAMK2-FAMILY	-	GPS
1081	S	Phosphorylation	Kinase	KCC2A	Q9UQM7	PhosphoELM
1092	Y	Phosphorylation	Kinase	SRC	P05480	PSP
1092	Y	Phosphorylation	Kinase	ABL1	P00519	GPS
1092	Y	Phosphorylation	Kinase	EGFR	P00533	PSP
1092	Y	Phosphorylation	Kinase	SRC	P12931	PSP
1110	Y	Phosphorylation	Kinase	SRC	P12931	PSP
1110	Y	Phosphorylation	Kinase	EGFR	P00533	PSP
1125	Y	Phosphorylation	Kinase	SRC64	-	PhosphoELM
1125	Y	Phosphorylation	Kinase	SRC	P12931	PSP
1166	S	Phosphorylation	Kinase	KCC2A	Q9UQM7	PhosphoELM
1166	S	Phosphorylation	Kinase	CAMK2-FAMILY	-	GPS
1166	S	Phosphorylation	Kinase	CAMK2A	P11275	PSP
1172	Y	Phosphorylation	Kinase	EGFR	P00533	PSP
1197	Y	Phosphorylation	Kinase	EGFR	P00533	PSP
1197	Y	Phosphorylation	Kinase	ABL1	P00519	GPS
-	K	Ubiquitination	E3 ubiquitin ligase	RNF126	Q9BV68	PMID:23418353
-	K	Ubiquitination	E3 ubiquitin ligase	RNF115	Q9Y4L5	PMID:23418353
-	K	Ubiquitination	E3 ubiquitin ligase	CBLB	Q13191	PMID:10542134
-	K	Ubiquitination	E3 ubiquitin ligase	NEDD4	P46934	PMID:20086093
-	K	Ubiquitination	E3 ubiquitin ligase	CBL	P22681	PMID:10428778
-	K	Ubiquitination	E3 ubiquitin ligase	SOCS5	O75159	PMID:15590694
-	K	Ubiquitination	E3 ubiquitin ligase	ITCH	Q96J02	PMID:12226085
-	K	Ubiquitination	E3 ubiquitin ligase	CBLC	Q9ULV8	PMID:22199232
-	K	Ubiquitination	E3 ubiquitin ligase	SMURF2	Q9HAU4	PMID:21750651
-	K	Ubiquitination	E3 ubiquitin ligase	CGRRF1	Q99675	PMID:31801577

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
11	K	ubiquitylation	Polyubiquitin linkage is mainly through 'Lys-63', but linkage through 'Lys-48', 'Lys-11' and 'Lys-29' also occurs.	16543144
29	K	ubiquitylation	Polyubiquitin linkage is mainly through 'Lys-63', but linkage through 'Lys-48', 'Lys-11' and 'Lys-29' also occurs.	16543144
48	K	ubiquitylation	Polyubiquitin linkage is mainly through 'Lys-63', but linkage through 'Lys-48', 'Lys-11' and 'Lys-29' also occurs.	16543144
63	K	ubiquitylation	Polyubiquitin linkage is mainly through 'Lys-63', but linkage through 'Lys-48', 'Lys-11' and 'Lys-29' also occurs.	16543144
678	T	Phosphorylation	Phosphorylation at Thr-678 and Thr-693 by PRKD1 inhibits EGF-induced MAPK8/JNK1 activation.	10523301
693	T	Phosphorylation	Phosphorylation at Ser-695 is partial and occurs only if Thr-693 is phosphorylated.	3138233
693	T	Phosphorylation	Phosphorylation at Thr-678 and Thr-693 by PRKD1 inhibits EGF-induced MAPK8/JNK1 activation.	3138233
695	S	Phosphorylation	Phosphorylation at Ser-695 is partial and occurs only if Thr-693 is phosphorylated.	3138233
1199	R	Methylation	Autophosphorylation at Tyr-1197 is stimulated by methylation at Arg-1199 and enhances interaction with PTPN6.	21258366
1199	R	Methylation	Methylation at Arg-1199 by PRMT5 stimulates phosphorylation at Tyr-1197.	21258366
1199	R	Phosphorylation	Autophosphorylation at Tyr-1197 is stimulated by methylation at Arg-1199 and enhances interaction with PTPN6.	21258366
1199	R	Phosphorylation	Methylation at Arg-1199 by PRMT5 stimulates phosphorylation at Tyr-1197.	21258366

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EGFR_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SHC1_HUMAN	SHC1	physical	16729043
SH3L1_HUMAN	SH3BGRL	physical	16729043
STA5A_HUMAN	STAT5A	physical	16729043
PTN11_HUMAN	PTPN11	physical	16729043
CRK_HUMAN	CRK	physical	16729043
CSK_HUMAN	CSK	physical	16729043
CBLB_HUMAN	CBLB	physical	16729043
GRB2_HUMAN	GRB2	physical	16729043
STAT3_HUMAN	STAT3	physical	15485908
CTNB1_HUMAN	CTNNB1	physical	9535896
CTND1_HUMAN	CTNND1	physical	9535896
PLAK_HUMAN	JUP	physical	9535896
ANDR_HUMAN	AR	physical	15305378
ANDR_HUMAN	AR	physical	15288768
CTNB1_HUMAN	CTNNB1	physical	11950845
EGFR_HUMAN	EGFR	physical	14576349
KPCA_HUMAN	PRKCA	physical	12878187
ZO1_HUMAN	TJP1	physical	12708492
WASP_HUMAN	WAS	physical	9307968
SHIP2_HUMAN	INPPL1	physical	11349134
AREG_HUMAN	AREG	physical	10085134
EGF_HUMAN	EGF	physical	10085134
CBLB_HUMAN	CBLB	physical	10086340
CBL_HUMAN	CBL	physical	10086340
CTNB1_HUMAN	CTNNB1	physical	9233779
SHC1_HUMAN	SHC1	physical	9544989
STAT1_HUMAN	STAT1	physical	10358079
STAT3_HUMAN	STAT3	physical	10358079
JAK2_HUMAN	JAK2	physical	10358079
PTK6_HUMAN	PTK6	physical	8940083
FAK2_HUMAN	PTK2B	physical	10777553
SRC_HUMAN	SRC	physical	10777553
GRB2_HUMAN	GRB2	physical	7527043
MPIP1_HUMAN	CDC25A	physical	11912208
CRK_HUMAN	CRK	physical	9642287
IGF1R_HUMAN	IGF1R	physical	17047074
GRB2_HUMAN	GRB2	physical	9050991
KAP0_HUMAN	PRKAR1A	physical	9050991
KAPCA_HUMAN	PRKACA	physical	9050991
PLD2_HUMAN	PLD2	physical	9837959
ARF4_HUMAN	ARF4	physical	12446727
PTN6_HUMAN	PTPN6	physical	7673163
PTN11_HUMAN	PTPN11	physical	7673163
SH23A_HUMAN	SH2D3A	physical	10187783
PLS1_HUMAN	PLSCR1	physical	12009895
GRB2_HUMAN	GRB2	physical	8647858
GRB14_HUMAN	GRB14	physical	8647858
RASA1_HUMAN	RASA1	physical	8647858
GRB2_HUMAN	GRB2	physical	7510700
SOS1_HUMAN	SOS1	physical	7510700
NRG1_HUMAN	NRG1	physical	7730382
CBL_HUMAN	CBL	physical	12061819
PLCG1_HUMAN	PLCG1	physical	12061819
SH3K1_HUMAN	SH3KBP1	physical	11894095
SOCS1_HUMAN	SOCS1	physical	12070153
SOCS3_HUMAN	SOCS3	physical	12070153
STAT1_HUMAN	STAT1	physical	12070153
CAV1_HUMAN	CAV1	physical	9374534
CAV3_HUMAN	CAV3	physical	9374534
ERBB3_HUMAN	ERBB3	physical	10527633
STA5B_HUMAN	STAT5B	physical	10558875
CEBPB_HUMAN	CEBPB	physical	12095417
SRC_HUMAN	SRC	physical	10971656
GAB1_HUMAN	GAB1	physical	11432805
RIPK1_HUMAN	RIPK1	physical	11116146
M3K14_HUMAN	MAP3K14	physical	11116146
PGFRB_HUMAN	PDGFRB	physical	9506992
MUC1_HUMAN	MUC1	physical	11483589
CBL_HUMAN	CBL	physical	18316398
CBL_HUMAN	CBL	physical	18508924
HGS_HUMAN	HGS	physical	18508924
CBL_HUMAN	CBL	physical	18273061
CBL_HUMAN	CBL	physical	17995934
NCAM1_HUMAN	NCAM1	physical	17995934
CBL_HUMAN	CBL	physical	17971399
GRB2_HUMAN	GRB2	physical	17971399
UBP8_MOUSE	Usp8	physical	17720156
CBL_HUMAN	CBL	physical	17545148
CBL_HUMAN	CBL	physical	17486068
MUC1_HUMAN	MUC1	physical	16983337
CBL_HUMAN	CBL	physical	16969069
HDAC6_HUMAN	HDAC6	physical	20133936
AIP_HUMAN	AIP	physical	20029029
PSA7_HUMAN	PSMA7	physical	20029029
MEGF6_HUMAN	MEGF6	physical	20029029
SRBS2_HUMAN	SORBS2	physical	20029029
HEXI1_HUMAN	HEXIM1	physical	20029029
AHSA1_HUMAN	AHSA1	physical	20029029
ALDOA_HUMAN	ALDOA	physical	20029029
DCUP_HUMAN	UROD	physical	20029029
UCHL1_HUMAN	UCHL1	physical	20029029
ENPL_HUMAN	HSP90B1	physical	20029029
CBR1_HUMAN	CBR1	physical	20029029
FAAA_HUMAN	FAH	physical	20029029
AATC_HUMAN	GOT1	physical	20029029
RAB3A_HUMAN	RAB3A	physical	20029029
CSRP1_HUMAN	CSRP1	physical	20029029
COF1_HUMAN	CFL1	physical	20029029
EF1G_HUMAN	EEF1G	physical	20029029
KAP1_HUMAN	PRKAR1B	physical	20029029
PUR9_HUMAN	ATIC	physical	20029029
STIP1_HUMAN	STIP1	physical	20029029
HSP74_HUMAN	HSPA4	physical	20029029
MDHC_HUMAN	MDH1	physical	20029029
PTGDS_HUMAN	PTGDS	physical	20029029
MATR3_HUMAN	MATR3	physical	20029029
SEPP1_HUMAN	SEPP1	physical	20029029
OAZ1_HUMAN	OAZ1	physical	20029029
PSMD4_HUMAN	PSMD4	physical	20029029
TPIS_HUMAN	TPI1	physical	20029029
GBRL2_HUMAN	GABARAPL2	physical	20029029
ARF6_HUMAN	ARF6	physical	20029029
CNTN2_HUMAN	CNTN2	physical	20029029
FKBP4_HUMAN	FKBP4	physical	20029029
AKA12_HUMAN	AKAP12	physical	20029029
PTN12_HUMAN	PTPN12	physical	20029029
PRDX1_HUMAN	PRDX1	physical	20029029
AHNK_HUMAN	AHNAK	physical	20029029
M3K12_HUMAN	MAP3K12	physical	20029029
GPM6B_HUMAN	GPM6B	physical	20029029
DCTN2_HUMAN	DCTN2	physical	20029029
CO9A3_HUMAN	COL9A3	physical	20029029
DYHC1_HUMAN	DYNC1H1	physical	20029029
FKBP8_HUMAN	FKBP8	physical	20029029
SPCS2_HUMAN	SPCS2	physical	20029029
PDK3_HUMAN	PDK3	physical	20029029
UB2V2_HUMAN	UBE2V2	physical	20029029
ADRM1_HUMAN	ADRM1	physical	20029029
GDS1_HUMAN	RAP1GDS1	physical	20029029
HSP7C_HUMAN	HSPA8	physical	20029029
PPP5_HUMAN	PPP5C	physical	20029029
FINC_HUMAN	FN1	physical	20029029
TPM1_HUMAN	TPM1	physical	20029029
TMCO3_HUMAN	TMCO3	physical	20029029
CEND_HUMAN	CEND1	physical	20029029
RUSC2_HUMAN	RUSC2	physical	20029029
SPRL1_HUMAN	SPARCL1	physical	20029029
HUMMR_HUMAN	MGARP	physical	20029029
PRCC_HUMAN	PRCC	physical	20029029
AP2M1_HUMAN	AP2M1	physical	20029029
NECD_HUMAN	NDN	physical	20029029
NOE1_HUMAN	OLFM1	physical	20029029
DNJC4_HUMAN	DNAJC4	physical	20029029
VAPA_HUMAN	VAPA	physical	20029029
HDAC6_HUMAN	HDAC6	physical	20029029
CHIP_HUMAN	STUB1	physical	20029029
PIN4_HUMAN	PIN4	physical	20029029
MAST1_HUMAN	MAST1	physical	20029029
PHOCN_HUMAN	MOB4	physical	20029029
CCD50_HUMAN	CCDC50	physical	16803894
CAV1_HUMAN	CAV1	physical	16407214
CBL_HUMAN	CBL	physical	16246327
ERBB2_HUMAN	ERBB2	physical	16207817
UBP8_HUMAN	USP8	physical	16120644
CBL_HUMAN	CBL	physical	16105874
PCNA_HUMAN	PCNA	physical	17115032
EPS15_HUMAN	EPS15	physical	15701692
EPN1_HUMAN	EPN1	physical	15701692
CBL_HUMAN	CBL	physical	15668240
PDC6I_HUMAN	PDCD6IP	physical	15456872
SH3K1_HUMAN	SH3KBP1	physical	15456872
SH3G2_HUMAN	SH3GL2	physical	15456872
CBL_HUMAN	CBL	physical	15282549
CBLB_HUMAN	CBLB	physical	16702950
UBS3B_HUMAN	UBASH3B	physical	15159412
UBS3A_HUMAN	UBASH3A	physical	15159412
CBL_HUMAN	CBL	physical	15159412
UBS3A_HUMAN	UBASH3A	physical	15107835
CBL_HUMAN	CBL	physical	15107835
CBL_HUMAN	CBL	physical	14505571
SH3K1_HUMAN	SH3KBP1	physical	12734385
CBL_HUMAN	CBL	physical	12734385
CBL_HUMAN	CBL	physical	12604776
CBL_HUMAN	CBL	physical	12593795
HS90A_HUMAN	HSP90AA1	physical	12006493
HSP74_HUMAN	HSPA4	physical	12006493
CBL_HUMAN	CBL	physical	10428778
IGF1R_HUMAN	IGF1R	physical	17307140
ERBB2_HUMAN	ERBB2	physical	17307140
GRB2_HUMAN	GRB2	physical	17242169
CBL_HUMAN	CBL	physical	17242169
ACK1_HUMAN	TNK2	physical	20086093
CBL_HUMAN	CBL	physical	21772844
SH3K1_HUMAN	SH3KBP1	physical	21635887
EGFR_HUMAN	EGFR	physical	19225046
CBL_HUMAN	CBL	physical	19225046
LEG1_HUMAN	LGALS1	physical	19225046
LEG3_HUMAN	LGALS3	physical	19225046
EPN1_HUMAN	EPN1	physical	21226813
EPS15_HUMAN	EPS15	physical	21226813
EPS15_HUMAN	EPS15	physical	19109251
CBL_HUMAN	CBL	physical	19531499
GRB2_HUMAN	GRB2	physical	19531499
SOS1_HUMAN	SOS1	physical	19531499
SHC1_HUMAN	SHC1	physical	19531499
VAV2_HUMAN	VAV2	physical	19531499
CBLB_HUMAN	CBLB	physical	19531499
UBC_HUMAN	UBC	physical	19531499
P85B_HUMAN	PIK3R2	physical	19531499
SMD2_HUMAN	SNRPD2	physical	19531499
ACTA_HUMAN	ACTA2	physical	19531499
EGF_HUMAN	EGF	physical	19531499
P85A_HUMAN	PIK3R1	physical	19531499
ERRFI_HUMAN	ERRFI1	physical	19531499
ATPG_HUMAN	ATP5C1	physical	19531499
1433Z_HUMAN	YWHAZ	physical	19531499
SOS2_HUMAN	SOS2	physical	19531499
CAV1_HUMAN	CAV1	physical	19446582
SMUF2_HUMAN	SMURF2	physical	21750651
GRB2_HUMAN	GRB2	physical	21596750
CBL_HUMAN	CBL	physical	19713535
CBL_HUMAN	CBL	physical	15210722
VAV2_HUMAN	VAV2	physical	20940296
CBL_HUMAN	CBL	physical	20940296
UBP8_MOUSE	Usp8	physical	17121848
CBL_HUMAN	CBL	physical	15962011
CBL_HUMAN	CBL	physical	14627991
STAT3_HUMAN	STAT3	physical	15950906
CBL_HUMAN	CBL	physical	22591401
ATX2_HUMAN	ATXN2	physical	18602463
CBL_HUMAN	CBL	physical	16849543
SH3K1_HUMAN	SH3KBP1	physical	16849543
HS90A_HUMAN	HSP90AA1	physical	16849543
CBL_HUMAN	CBL	physical	15465819
SH3K1_HUMAN	SH3KBP1	physical	12771190
PDC6I_HUMAN	PDCD6IP	physical	12771190
CBL_HUMAN	CBL	physical	9756944
PTN11_HUMAN	PTPN11	physical	9756944
SHC1_HUMAN	SHC1	physical	9756944
STAT3_HUMAN	STAT3	physical	9756944
PLCG1_HUMAN	PLCG1	physical	9756944
SHC1_HUMAN	SHC1	physical	9130710
CBL_HUMAN	CBL	physical	9130710
P85A_HUMAN	PIK3R1	physical	21701776
SHC1_HUMAN	SHC1	physical	11370743
CBL_HUMAN	CBL	physical	11370743
UBS3B_HUMAN	UBASH3B	physical	17880946
CBL_HUMAN	CBL	physical	17880946
CBL_HUMAN	CBL	physical	15383614
STAT3_HUMAN	STAT3	physical	21573184
SRC_HUMAN	SRC	physical	21573184
CBLB_HUMAN	CBLB	physical	11375397
CBL_HUMAN	CBL	physical	19836242
CBL_HUMAN	CBL	physical	22833562
CBL_HUMAN	CBL	physical	19578043
ACK1_HUMAN	TNK2	physical	17182860
CBL_HUMAN	CBL	physical	17182860
CBL_HUMAN	CBL	physical	16923119
SHC1_HUMAN	SHC1	physical	11408594
GRB2_HUMAN	GRB2	physical	11408594
EPS8_HUMAN	EPS8	physical	11408594
CBL_HUMAN	CBL	physical	11408594
ERBB2_HUMAN	ERBB2	physical	11408594
STAM2_HUMAN	STAM2	physical	17403676
RIN1_HUMAN	RIN1	physical	17403676
CBL_MOUSE	Cbl	physical	19263517
SHC1_HUMAN	SHC1	physical	10595738
GRB2_HUMAN	GRB2	physical	10595738
CRK_HUMAN	CRK	physical	10595738
ERBB2_HUMAN	ERBB2	physical	21044682
CBL_HUMAN	CBL	physical	7782294
CBL_HUMAN	CBL	physical	7592693
GRB2_HUMAN	GRB2	physical	7592693
GRB2_HUMAN	GRB2	physical	19289468
SOS1_HUMAN	SOS1	physical	19289468
ACK1_HUMAN	TNK2	physical	18435854
HS90A_HUMAN	HSP90AA1	physical	16024644
EMD_HUMAN	EMD	physical	20937808
SC61B_HUMAN	SEC61B	physical	20937808
HGS_HUMAN	HGS	physical	15212941
STAM2_HUMAN	STAM2	physical	15212941
TM1L1_HUMAN	TOM1L1	physical	19798056
CRK_HUMAN	CRK	physical	9617486
EGFR_HUMAN	EGFR	physical	18271526
CBL_HUMAN	CBL	physical	18271526
GRB2_HUMAN	GRB2	physical	18271526
SOS1_HUMAN	SOS1	physical	18271526
RBM10_HUMAN	RBM10	physical	18271526
HSP74_HUMAN	HSPA4	physical	18271526
SHC1_HUMAN	SHC1	physical	18271526
TRAF2_HUMAN	TRAF2	physical	18271526
VAV2_HUMAN	VAV2	physical	18271526
HNRH1_HUMAN	HNRNPH1	physical	18271526
PRDX1_HUMAN	PRDX1	physical	18271526
BCLF1_HUMAN	BCLAF1	physical	18271526
CK084_HUMAN	C11orf84	physical	18271526
DOCK4_HUMAN	DOCK4	physical	18271526
MYCBP_HUMAN	MYCBP	physical	18271526
CRKL_HUMAN	CRKL	physical	18271526
TAB1_HUMAN	TAB1	physical	18271526
RIOK1_HUMAN	RIOK1	physical	18271526
JAK1_HUMAN	JAK1	physical	18271526
EGF_HUMAN	EGF	physical	18271526
UBS3B_HUMAN	UBASH3B	physical	18271526
SOS2_HUMAN	SOS2	physical	18271526
ERRFI_HUMAN	ERRFI1	physical	18271526
GAB1_HUMAN	GAB1	physical	18271526
ACK1_HUMAN	TNK2	physical	18271526
CDK1_HUMAN	CDK1	physical	18271526
FER_HUMAN	FER	physical	18271526
CBLB_HUMAN	CBLB	physical	18271526
DDX60_HUMAN	DDX60	physical	18271526
OD3L2_HUMAN	ODF3L2	physical	18271526
HCFC1_HUMAN	HCFC1	physical	18271526
IRS2_HUMAN	IRS2	physical	18271526
RBM41_HUMAN	RBM41	physical	18271526
SHC1_HUMAN	SHC1	physical	10049786
CBL_HUMAN	CBL	physical	10635327
SHC1_HUMAN	SHC1	physical	10635327
PICAL_HUMAN	PICALM	physical	22939629
MPV17_HUMAN	MPV17	physical	22939629
TRPV1_HUMAN	TRPV1	physical	19155296
CBL_HUMAN	CBL	physical	19155296
ESR1_HUMAN	ESR1	physical	17284441
UBP8_HUMAN	USP8	physical	23333852
CBL_HUMAN	CBL	physical	23158001
ERBB4_HUMAN	ERBB4	physical	23153581
ENPL_HUMAN	HSP90B1	physical	12471035
HS90A_HUMAN	HSP90AA1	physical	12471035
HS90B_HUMAN	HSP90AB1	physical	12471035
GRP78_HUMAN	HSPA5	physical	12471035
HSP7C_HUMAN	HSPA8	physical	12471035
CDC37_HUMAN	CDC37	physical	12471035
CTGF_HUMAN	CTGF	physical	23175185
SRC_HUMAN	SRC	physical	23175185
CBL_HUMAN	CBL	physical	23175185
RN126_HUMAN	RNF126	physical	23418353
CBL_HUMAN	CBL	physical	20562913
UBC_HUMAN	UBC	physical	11916981
CBL_HUMAN	CBL	physical	8662998
SHC1_HUMAN	SHC1	physical	8662998
GRB2_HUMAN	GRB2	physical	8662998
P85A_HUMAN	PIK3R1	physical	8662998
FES_HUMAN	FES	physical	16273093
NCK1_HUMAN	NCK1	physical	16273093
PLCG2_HUMAN	PLCG2	physical	16273093
PLCG1_HUMAN	PLCG1	physical	16273093
RASA1_HUMAN	RASA1	physical	16273093
CBL_HUMAN	CBL	physical	23457600
P85A_HUMAN	PIK3R1	physical	16273093
SHC1_HUMAN	SHC1	physical	16273093
IRS1_HUMAN	IRS1	physical	16273093
ABL2_HUMAN	ABL2	physical	16273093
ZAP70_HUMAN	ZAP70	physical	16273093
KSYK_HUMAN	SYK	physical	16273093
CRK_HUMAN	CRK	physical	16273093
NUMB_HUMAN	NUMB	physical	16273093
BLK_HUMAN	BLK	physical	16273093
BMX_HUMAN	BMX	physical	16273093
GRB2_HUMAN	GRB2	physical	16273093
SHC2_HUMAN	SHC2	physical	16273093
PTN11_HUMAN	PTPN11	physical	16273093
SLAP1_HUMAN	SLA	physical	16273093
JIP2_HUMAN	MAPK8IP2	physical	16273093
PTK6_HUMAN	PTK6	physical	16273093
DOK6_HUMAN	DOK6	physical	16273093
ANS1B_HUMAN	ANKS1B	physical	16273093
CLNK_HUMAN	CLNK	physical	16273093
TENS4_HUMAN	TNS4	physical	16273093
DOK4_HUMAN	DOK4	physical	16273093
RIN2_HUMAN	RIN2	physical	16273093
SHC3_HUMAN	SHC3	physical	16273093
P55G_HUMAN	PIK3R3	physical	16273093
ANS1A_HUMAN	ANKS1A	physical	16273093
APBB2_HUMAN	APBB2	physical	16273093
VAV_HUMAN	VAV1	physical	16273093
SH22A_HUMAN	SH2D2A	physical	16273093
SH2B1_HUMAN	SH2B1	physical	16273093
CISH_HUMAN	CISH	physical	16273093
DOK5_HUMAN	DOK5	physical	16273093
DP13A_HUMAN	APPL1	physical	16273093
JIP1_HUMAN	MAPK8IP1	physical	16273093
SH2B3_HUMAN	SH2B3	physical	16273093
TLN1_HUMAN	TLN1	physical	16273093
NUMBL_HUMAN	NUMBL	physical	16273093
AN13A_HUMAN	ANKRD13A	physical	22298428
AN13B_HUMAN	ANKRD13B	physical	22298428
AN13D_HUMAN	ANKRD13D	physical	22298428
EGFR_HUMAN	EGFR	physical	16777603
HGS_HUMAN	HGS	physical	23602387
HGS_HUMAN	HGS	physical	23477725
UBP8_HUMAN	USP8	physical	23477725
CBL_HUMAN	CBL	physical	23774213
SYGP1_MOUSE	Syngap1	physical	8610433
CBL_HUMAN	CBL	physical	23799367
GRB2_HUMAN	GRB2	physical	23799367
STAT3_HUMAN	STAT3	physical	20145033
CBL_HUMAN	CBL	physical	19947936
EGFR_HUMAN	EGFR	physical	23956138
LEG1_HUMAN	LGALS1	physical	23956138
TBB5_HUMAN	TUBB	physical	23956138
TBA4A_HUMAN	TUBA4A	physical	23956138
TBB4B_HUMAN	TUBB4B	physical	23956138
TBB4A_HUMAN	TUBB4A	physical	23956138
TBB2A_HUMAN	TUBB2A	physical	23956138
TBB3_HUMAN	TUBB3	physical	23956138
TBB6_HUMAN	TUBB6	physical	23956138
HBA_HUMAN	HBA1	physical	23956138
HSP7C_HUMAN	HSPA8	physical	23956138
GRB2_HUMAN	GRB2	physical	23956138
LEG3_HUMAN	LGALS3	physical	23956138
XPO2_HUMAN	CSE1L	physical	23956138
EF1A1_HUMAN	EEF1A1	physical	23956138
KRT86_HUMAN	KRT86	physical	23956138
GRP78_HUMAN	HSPA5	physical	23956138
AP1S1_HUMAN	AP1S1	physical	23956138
IPO9_HUMAN	IPO9	physical	23956138
ATX10_HUMAN	ATXN10	physical	23956138
IMB1_HUMAN	KPNB1	physical	23956138
SMD1_HUMAN	SNRPD1	physical	23956138
HSP72_HUMAN	HSPA2	physical	23956138
HS90B_HUMAN	HSP90AB1	physical	23956138
XPO1_HUMAN	XPO1	physical	23956138
CIP2A_HUMAN	KIAA1524	physical	23956138
AP1M2_HUMAN	AP1M2	physical	23956138
IPO7_HUMAN	IPO7	physical	23956138
XPOT_HUMAN	XPOT	physical	23956138
CAVN1_HUMAN	PTRF	physical	23956138
TNPO1_HUMAN	TNPO1	physical	23956138
IPO5_HUMAN	IPO5	physical	23956138
SHC1_HUMAN	SHC1	physical	23956138
STAT3_HUMAN	STAT3	physical	23956138
HS90A_HUMAN	HSP90AA1	physical	23956138
2AAA_HUMAN	PPP2R1A	physical	23956138
DNJA1_HUMAN	DNAJA1	physical	23956138
BAG2_HUMAN	BAG2	physical	23956138
DHB12_HUMAN	HSD17B12	physical	23956138
SGPL1_HUMAN	SGPL1	physical	23956138
EXOC7_HUMAN	EXOC7	physical	23956138
XPO4_HUMAN	XPO4	physical	23956138
UBS3B_HUMAN	UBASH3B	physical	23956138
2ABA_HUMAN	PPP2R2A	physical	23956138
1433Z_HUMAN	YWHAZ	physical	23956138
GCN1_HUMAN	GCN1L1	physical	23956138
EI2BB_HUMAN	EIF2B2	physical	23956138
CDK1_HUMAN	CDK1	physical	23956138
SERA_HUMAN	PHGDH	physical	23956138
FBX6_HUMAN	FBXO6	physical	23956138
LANC2_HUMAN	LANCL2	physical	23956138
SAAL1_HUMAN	SAAL1	physical	23956138
SPTC1_HUMAN	SPTLC1	physical	23956138
GEMI6_HUMAN	GEMIN6	physical	23956138
PRDX1_HUMAN	PRDX1	physical	23956138
DNJA2_HUMAN	DNAJA2	physical	23956138
AP2M1_HUMAN	AP2M1	physical	23956138
P85B_HUMAN	PIK3R2	physical	23956138
HOOK2_HUMAN	HOOK2	physical	23956138
RANG_HUMAN	RANBP1	physical	23956138
PEX19_HUMAN	PEX19	physical	23956138
ARL1_HUMAN	ARL1	physical	23956138
VAPA_HUMAN	VAPA	physical	23956138
PPP6_HUMAN	PPP6C	physical	23956138
TNPO3_HUMAN	TNPO3	physical	23956138
CDC37_HUMAN	CDC37	physical	23956138
AP1G2_HUMAN	AP1G2	physical	23956138
AP2A1_HUMAN	AP2A1	physical	23956138
2AAB_HUMAN	PPP2R1B	physical	23956138
TNPO2_HUMAN	TNPO2	physical	23956138
2A5E_HUMAN	PPP2R5E	physical	23956138
AP2B1_HUMAN	AP2B1	physical	23956138
RPN1_HUMAN	RPN1	physical	23956138
LTN1_HUMAN	LTN1	physical	23956138
THADA_HUMAN	THADA	physical	23956138
S61A1_HUMAN	SEC61A1	physical	23956138
EXOC5_HUMAN	EXOC5	physical	23956138
TPPC3_HUMAN	TRAPPC3	physical	23956138
PDIA3_HUMAN	PDIA3	physical	23956138
COG7_HUMAN	COG7	physical	23956138
IQGA3_HUMAN	IQGAP3	physical	23956138
PK3CB_HUMAN	PIK3CB	physical	23956138
G3P_HUMAN	GAPDH	physical	23956138
MMS19_HUMAN	MMS19	physical	23956138
STRAP_HUMAN	STRAP	physical	23956138
MON2_HUMAN	MON2	physical	23956138
EI2BG_HUMAN	EIF2B3	physical	23956138
SYDC_HUMAN	DARS	physical	23956138
DFNA5_HUMAN	DFNA5	physical	23956138
EXOC4_HUMAN	EXOC4	physical	23956138
COG5_HUMAN	COG5	physical	23956138
BZW2_HUMAN	BZW2	physical	23956138
DAAF5_HUMAN	DNAAF5	physical	23956138
RCN2_HUMAN	RCN2	physical	23956138
COG6_HUMAN	COG6	physical	23956138
THEM6_HUMAN	THEM6	physical	23956138
S39AB_HUMAN	SLC39A11	physical	23956138
DNJA3_HUMAN	DNAJA3	physical	23956138
COG4_HUMAN	COG4	physical	23956138
PFKAP_HUMAN	PFKP	physical	23956138
TECR_HUMAN	TECR	physical	23956138
BUB3_HUMAN	BUB3	physical	23956138
TIM50_HUMAN	TIMM50	physical	23956138
AP1M1_HUMAN	AP1M1	physical	23956138
VATH_HUMAN	ATP6V1H	physical	23956138
OS9_HUMAN	OS9	physical	23956138
XPO7_HUMAN	XPO7	physical	23956138
DJB12_HUMAN	DNAJB12	physical	23956138
PDIA1_HUMAN	P4HB	physical	23956138
IPO4_HUMAN	IPO4	physical	23956138
PP6R1_HUMAN	PPP6R1	physical	23956138
ERRFI_HUMAN	ERRFI1	physical	23956138
SE1L1_HUMAN	SEL1L	physical	23956138
USP9X_HUMAN	USP9X	physical	23956138
SYEP_HUMAN	EPRS	physical	23956138
NCDN_HUMAN	NCDN	physical	23956138
EXOC8_HUMAN	EXOC8	physical	23956138
SOS2_HUMAN	SOS2	physical	23956138
PFKAL_HUMAN	PFKL	physical	23956138
STAT1_HUMAN	STAT1	physical	23956138
XPO5_HUMAN	XPO5	physical	23956138
TTC27_HUMAN	TTC27	physical	23956138
AP2A2_HUMAN	AP2A2	physical	23956138
ITIH2_HUMAN	ITIH2	physical	23956138
PRKDC_HUMAN	PRKDC	physical	23956138
PHLA1_HUMAN	PHLDA1	physical	23956138
HEAT3_HUMAN	HEATR3	physical	23956138
DDX20_HUMAN	DDX20	physical	23956138
IPO11_HUMAN	IPO11	physical	23956138
AN13A_HUMAN	ANKRD13A	physical	23956138
LEG8_HUMAN	LGALS8	physical	23956138
PSMD2_HUMAN	PSMD2	physical	23956138
IPO13_HUMAN	IPO13	physical	23956138
TPP1_HUMAN	TPP1	physical	23956138
EXC6B_HUMAN	EXOC6B	physical	23956138
SYMC_HUMAN	MARS	physical	23956138
TBRG4_HUMAN	TBRG4	physical	23956138
ZW10_HUMAN	ZW10	physical	23956138
ARHG5_HUMAN	ARHGEF5	physical	23956138
AP1G1_HUMAN	AP1G1	physical	23956138
IPO8_HUMAN	IPO8	physical	23956138
FPPS_HUMAN	FDPS	physical	23956138
COG1_HUMAN	COG1	physical	23956138
AT2A2_HUMAN	ATP2A2	physical	23956138
NUP85_HUMAN	NUP85	physical	23956138
XPO6_HUMAN	XPO6	physical	23956138
GEMI4_HUMAN	GEMIN4	physical	23956138
AL3A2_HUMAN	ALDH3A2	physical	23956138
NUP93_HUMAN	NUP93	physical	23956138
RAGP1_HUMAN	RANGAP1	physical	23956138
BIG1_HUMAN	ARFGEF1	physical	23956138
EXOC6_HUMAN	EXOC6	physical	23956138
ARMC8_HUMAN	ARMC8	physical	23956138
TELO2_HUMAN	TELO2	physical	23956138
EI2BE_HUMAN	EIF2B5	physical	23956138
SOS1_HUMAN	SOS1	physical	23956138
PRGC1_HUMAN	PPARGC1A	physical	23956138
SYIC_HUMAN	IARS	physical	23956138
EXOC3_HUMAN	EXOC3	physical	23956138
NAL10_HUMAN	NLRP10	physical	23956138
BIG3_HUMAN	KIAA1244	physical	23956138
MTOR_HUMAN	MTOR	physical	23956138
DOP2_HUMAN	DOPEY2	physical	23956138
CNDG2_HUMAN	NCAPG2	physical	23956138
TTI1_HUMAN	TTI1	physical	23956138
GBF1_HUMAN	GBF1	physical	23956138
SMC2_HUMAN	SMC2	physical	23956138
RN213_HUMAN	RNF213	physical	23956138
ATR_HUMAN	ATR	physical	23956138
NBEL2_HUMAN	NBEAL2	physical	23956138
FDFT_HUMAN	FDFT1	physical	23956138
SYRC_HUMAN	RARS	physical	23956138
ACOT9_HUMAN	ACOT9	physical	23956138
TOR4A_HUMAN	TOR4A	physical	23956138
PLAP_HUMAN	PLAA	physical	23956138
TTI2_HUMAN	TTI2	physical	23956138
WDR26_HUMAN	WDR26	physical	23956138
CNDH2_HUMAN	NCAPH2	physical	23956138
VAC14_HUMAN	VAC14	physical	23956138
CD59_HUMAN	CD59	physical	12577067
CAV1_HUMAN	CAV1	physical	16799092
EGFR_HUMAN	EGFR	physical	23972990
CAV2_HUMAN	CAV2	physical	16799092
CLCA_HUMAN	CLTA	physical	16799092
CLH2_HUMAN	CLTCL1	physical	16799092
GRB2_HUMAN	GRB2	physical	16799092
HXC10_HUMAN	HOXC10	physical	16799092
LYN_HUMAN	LYN	physical	16799092
S10A7_HUMAN	S100A7	physical	16799092
S10A9_HUMAN	S100A9	physical	16799092
SEC13_HUMAN	SEC13	physical	16799092
G3P_HUMAN	GAPDH	physical	16799092
1433S_HUMAN	SFN	physical	16799092
4F2_HUMAN	SLC3A2	physical	16799092
AT1A1_HUMAN	ATP1A1	physical	16799092
AT1B1_HUMAN	ATP1B1	physical	16799092
CD166_HUMAN	ALCAM	physical	16799092
ICAM1_HUMAN	ICAM1	physical	16799092
TBA1A_HUMAN	TUBA1A	physical	16799092
CBL_HUMAN	CBL	physical	24714105
CHIP_HUMAN	STUB1	physical	24722501
PLCG1_HUMAN	PLCG1	physical	24797263
GRB2_HUMAN	GRB2	physical	24797263
UBS3B_HUMAN	UBASH3B	physical	24797263
SOS1_HUMAN	SOS1	physical	24797263
SOS2_HUMAN	SOS2	physical	24797263
CBL_HUMAN	CBL	physical	24797263
SHC1_HUMAN	SHC1	physical	24797263
PANK4_HUMAN	PANK4	physical	24797263
CSK_HUMAN	CSK	physical	24797263
HUWE1_HUMAN	HUWE1	physical	24797263
OXSR1_HUMAN	OXSR1	physical	24797263
AAKG1_HUMAN	PRKAG1	physical	24797263
KS6A3_HUMAN	RPS6KA3	physical	24797263
ERRFI_HUMAN	ERRFI1	physical	24797263
PLK1_HUMAN	PLK1	physical	24797263
F263_HUMAN	PFKFB3	physical	24797263
EPHA2_HUMAN	EPHA2	physical	24797263
AT1A1_HUMAN	ATP1A1	physical	24797263
DNM1L_HUMAN	DNM1L	physical	24797263
SAE2_HUMAN	UBA2	physical	24797263
MP2K2_HUMAN	MAP2K2	physical	24797263
HXK2_HUMAN	HK2	physical	24797263
MP2K4_HUMAN	MAP2K4	physical	24797263
AP3D1_HUMAN	AP3D1	physical	24797263
DYN2_HUMAN	DNM2	physical	24797263
IRS4_HUMAN	IRS4	physical	24797263
UBR4_HUMAN	UBR4	physical	24797263
RIOK2_HUMAN	RIOK2	physical	24797263
S12A2_HUMAN	SLC12A2	physical	24797263
CTND1_HUMAN	CTNND1	physical	24797263
MP2K3_HUMAN	MAP2K3	physical	24797263
VAV2_HUMAN	VAV2	physical	24797263
HXK1_HUMAN	HK1	physical	24797263
ATP5L_HUMAN	ATP5L	physical	24797263
PTPRF_HUMAN	PTPRF	physical	24797263
RHG01_HUMAN	ARHGAP1	physical	24797263
ITCH_HUMAN	ITCH	physical	24797263
PDK1_HUMAN	PDK1	physical	24797263
PFKAP_HUMAN	PFKP	physical	24797263
SNX2_HUMAN	SNX2	physical	24797263
ARF6_HUMAN	ARF6	physical	24797263
TBK1_HUMAN	TBK1	physical	24797263
PLD3_HUMAN	PLD3	physical	24797263
PFKAL_HUMAN	PFKL	physical	24797263
STK26_HUMAN	STK26	physical	24797263
2A5G_HUMAN	PPP2R5C	physical	24797263
UB2G2_HUMAN	UBE2G2	physical	24797263
AP3M1_HUMAN	AP3M1	physical	24797263
YES_HUMAN	YES1	physical	24797263
PFKAM_HUMAN	PFKM	physical	24797263
AAPK1_HUMAN	PRKAA1	physical	24797263
AP1S2_HUMAN	AP1S2	physical	24797263
AP1G1_HUMAN	AP1G1	physical	24797263
AP1S1_HUMAN	AP1S1	physical	24797263
AP1B1_HUMAN	AP1B1	physical	24797263
KC1A_HUMAN	CSNK1A1	physical	24797263
AP1M1_HUMAN	AP1M1	physical	24797263
PPAC_HUMAN	ACP1	physical	24797263
CSK21_HUMAN	CSNK2A1	physical	24797263
AP2A1_HUMAN	AP2A1	physical	24797263
AP2B1_HUMAN	AP2B1	physical	24797263
AP2S1_HUMAN	AP2S1	physical	24797263
AP2A2_HUMAN	AP2A2	physical	24797263
AP2M1_HUMAN	AP2M1	physical	24797263
CDK5_HUMAN	CDK5	physical	24797263
CBLB_HUMAN	CBLB	physical	24797263
E2AK2_HUMAN	EIF2AK2	physical	24797263
UCK2_HUMAN	UCK2	physical	24797263
UBE2S_HUMAN	UBE2S	physical	24797263
STAT1_HUMAN	STAT1	physical	24797263
AP3S1_HUMAN	AP3S1	physical	24797263
VRK1_HUMAN	VRK1	physical	24797263
AKT2_HUMAN	AKT2	physical	24797263
SOCS5_HUMAN	SOCS5	physical	15590694
CBL_HUMAN	CBL	physical	22976291
DERL1_HUMAN	DERL1	physical	23306155
PML_HUMAN	PML	physical	23563092
DCBD2_HUMAN	DCBLD2	physical	25061874
ERBB4_HUMAN	ERBB4	physical	25140053
CBL_HUMAN	CBL	physical	25140053
LRSM1_HUMAN	LRSAM1	physical	15256501
S61A1_HUMAN	SEC61A1	physical	20937808
CBL_HUMAN	CBL	physical	15735736
EGFR_HUMAN	EGFR	physical	24797263
ARL1_HUMAN	ARL1	physical	24797263
DSG2_HUMAN	DSG2	physical	24797263
SSBP_HUMAN	SSBP1	physical	24797263
MYO1B_HUMAN	MYO1B	physical	24797263
NGLY1_HUMAN	NGLY1	physical	24797263
CALX_HUMAN	CANX	physical	24797263
DPM1_HUMAN	DPM1	physical	24797263
DNJA1_HUMAN	DNAJA1	physical	24797263
DJB11_HUMAN	DNAJB11	physical	24797263
HCD2_HUMAN	HSD17B10	physical	24797263
DC1L1_HUMAN	DYNC1LI1	physical	24797263
DNJA3_HUMAN	DNAJA3	physical	24797263
FAF2_HUMAN	FAF2	physical	24797263
SYYC_HUMAN	YARS	physical	24797263
IDHP_HUMAN	IDH2	physical	24797263
ECM29_HUMAN	KIAA0368	physical	24797263
DAAF5_HUMAN	DNAAF5	physical	24797263
ST1A1_HUMAN	SULT1A1	physical	24797263
TFR1_HUMAN	TFRC	physical	24797263
CLPX_HUMAN	CLPX	physical	24797263
SRPRA_HUMAN	SRPR	physical	24797263
SYVC_HUMAN	VARS	physical	24797263
LRC40_HUMAN	LRRC40	physical	24797263
MRT4_HUMAN	MRTO4	physical	24797263
EIF3M_HUMAN	EIF3M	physical	24797263
MRRP1_HUMAN	TRMT10C	physical	24797263
TIM23_HUMAN	TIMM23	physical	24797263
NUP93_HUMAN	NUP93	physical	24797263
SSRD_HUMAN	SSR4	physical	24797263
EHD4_HUMAN	EHD4	physical	24797263
RPR1A_HUMAN	RPRD1A	physical	24797263
MYO1D_HUMAN	MYO1D	physical	24797263
FBRL_HUMAN	FBL	physical	24797263
ECHB_HUMAN	HADHB	physical	24797263
AFG32_HUMAN	AFG3L2	physical	24797263
CCD47_HUMAN	CCDC47	physical	24797263
SMC1A_HUMAN	SMC1A	physical	24797263
SMC3_HUMAN	SMC3	physical	24797263
VATH_HUMAN	ATP6V1H	physical	24797263
NDUA9_HUMAN	NDUFA9	physical	24797263
UMPS_HUMAN	UMPS	physical	24797263
ITPA_HUMAN	ITPA	physical	24797263
SLN11_HUMAN	SLFN11	physical	24797263
DNJA2_HUMAN	DNAJA2	physical	24797263
CLPP_HUMAN	CLPP	physical	24797263
CPVL_HUMAN	CPVL	physical	24797263
TM9S3_HUMAN	TM9SF3	physical	24797263
LONM_HUMAN	LONP1	physical	24797263
RL38_HUMAN	RPL38	physical	24797263
RU2A_HUMAN	SNRPA1	physical	24797263
COPA_HUMAN	COPA	physical	24797263
APT_HUMAN	APRT	physical	24797263
NSF_HUMAN	NSF	physical	24797263
NSUN5_HUMAN	NSUN5	physical	24797263
ATAD1_HUMAN	ATAD1	physical	24797263
AIFM1_HUMAN	AIFM1	physical	24797263
PDIP2_HUMAN	POLDIP2	physical	24797263
WDR6_HUMAN	WDR6	physical	24797263
SCFD1_HUMAN	SCFD1	physical	24797263
NDUS1_HUMAN	NDUFS1	physical	24797263
OAT_HUMAN	OAT	physical	24797263
SAMH1_HUMAN	SAMHD1	physical	24797263
MGST1_HUMAN	MGST1	physical	24797263
NDUS3_HUMAN	NDUFS3	physical	24797263
RUXF_HUMAN	SNRPF	physical	24797263
CN37_HUMAN	CNP	physical	24797263
RPN1_HUMAN	RPN1	physical	24797263
ACDSB_HUMAN	ACADSB	physical	24797263
ORC5_HUMAN	ORC5	physical	24797263
EI2BD_HUMAN	EIF2B4	physical	24797263
TRUA_HUMAN	PUS1	physical	24797263
SDF2L_HUMAN	SDF2L1	physical	24797263
MIC60_HUMAN	IMMT	physical	24797263
EI2BB_HUMAN	EIF2B2	physical	24797263
SYTC_HUMAN	TARS	physical	24797263
DDX47_HUMAN	DDX47	physical	24797263
ARP2_HUMAN	ACTR2	physical	24797263
ACOT9_HUMAN	ACOT9	physical	24797263
EI2BA_HUMAN	EIF2B1	physical	24797263
1A02_HUMAN	HLA-A	physical	24797263
1A03_HUMAN	HLA-A	physical	24797263
1A01_HUMAN	HLA-A	physical	24797263
1A26_HUMAN	HLA-A	physical	24797263
VPS4B_HUMAN	VPS4B	physical	24797263
EHD1_HUMAN	EHD1	physical	24797263
P5CR2_HUMAN	PYCR2	physical	24797263
MYO1C_HUMAN	MYO1C	physical	24797263
CUL4B_HUMAN	CUL4B	physical	24797263
DRS7B_HUMAN	DHRS7B	physical	24797263
RFC5_HUMAN	RFC5	physical	24797263
OSBP1_HUMAN	OSBP	physical	24797263
YBEY_HUMAN	YBEY	physical	24797263
EF1B_HUMAN	EEF1B2	physical	24797263
PLAK_HUMAN	JUP	physical	24797263
GSH0_HUMAN	GCLM	physical	24797263
GSTK1_HUMAN	GSTK1	physical	24797263
TTC37_HUMAN	TTC37	physical	24797263
KAD4_HUMAN	AK4	physical	24797263
SYCM_HUMAN	CARS2	physical	24797263
MIC10_HUMAN	MINOS1	physical	24797263
EI2BG_HUMAN	EIF2B3	physical	24797263
PELO_HUMAN	PELO	physical	24797263
RM10_HUMAN	MRPL10	physical	24797263
FACR1_HUMAN	FAR1	physical	24797263
XPOT_HUMAN	XPOT	physical	24797263
CTBP1_HUMAN	CTBP1	physical	24797263
ABCF2_HUMAN	ABCF2	physical	24797263
MPC2_HUMAN	MPC2	physical	24797263
LIMA1_HUMAN	LIMA1	physical	24797263
ILVBL_HUMAN	ILVBL	physical	24797263
TIM50_HUMAN	TIMM50	physical	24797263
CND3_HUMAN	NCAPG	physical	24797263
SYTM_HUMAN	TARS2	physical	24797263
COX2_HUMAN	COX2	physical	24797263
TBB6_HUMAN	TUBB6	physical	24797263
PNO1_HUMAN	PNO1	physical	24797263
IFIT5_HUMAN	IFIT5	physical	24797263
EIF3K_HUMAN	EIF3K	physical	24797263
MIC19_HUMAN	CHCHD3	physical	24797263
PUM1_HUMAN	PUM1	physical	24797263
TOIP1_HUMAN	TOR1AIP1	physical	24797263
GNAS3_HUMAN	GNAS	physical	24797263
GNAS2_HUMAN	GNAS	physical	24797263
ALEX_HUMAN	GNAS	physical	24797263
GNAS1_HUMAN	GNAS	physical	24797263
4F2_HUMAN	SLC3A2	physical	24797263
EIF3F_HUMAN	EIF3F	physical	24797263
CMS1_HUMAN	CMSS1	physical	24797263
EI2BE_HUMAN	EIF2B5	physical	24797263
RS15A_HUMAN	RPS15A	physical	24797263
SGMR2_HUMAN	TMEM97	physical	24797263
ERF1_HUMAN	ETF1	physical	24797263
CND2_HUMAN	NCAPH	physical	24797263
RFC3_HUMAN	RFC3	physical	24797263
TOM22_HUMAN	TOMM22	physical	24797263
STT3A_HUMAN	STT3A	physical	24797263
GCP2_HUMAN	TUBGCP2	physical	24797263
ASNS_HUMAN	ASNS	physical	24797263
HELLS_HUMAN	HELLS	physical	24797263
LARP4_HUMAN	LARP4	physical	24797263
PON2_HUMAN	PON2	physical	24797263
ABCD3_HUMAN	ABCD3	physical	24797263
CDIPT_HUMAN	CDIPT	physical	24797263
SDF2_HUMAN	SDF2	physical	24797263
DIM1_HUMAN	DIMT1	physical	24797263
BCCIP_HUMAN	BCCIP	physical	24797263
TEBP_HUMAN	PTGES3	physical	24797263
PYC_HUMAN	PC	physical	24797263
SRPRB_HUMAN	SRPRB	physical	24797263
SCAM3_HUMAN	SCAMP3	physical	24797263
NAA10_HUMAN	NAA10	physical	24797263
UTP15_HUMAN	UTP15	physical	24797263
GBB2_HUMAN	GNB2	physical	24797263
TRM2A_HUMAN	TRMT2A	physical	24797263
COQ8A_HUMAN	ADCK3	physical	24797263
VAV3_HUMAN	VAV3	physical	24797263
SRC8_HUMAN	CTTN	physical	24797263
RER1_HUMAN	RER1	physical	24797263
IDH3B_HUMAN	IDH3B	physical	24797263
LRWD1_HUMAN	LRWD1	physical	24797263
CF120_HUMAN	C6orf120	physical	24797263
BZW1_HUMAN	BZW1	physical	24797263
AAAT_HUMAN	SLC1A5	physical	24797263
SPTC1_HUMAN	SPTLC1	physical	24797263
TRM1L_HUMAN	TRMT1L	physical	24797263
NSUN2_HUMAN	NSUN2	physical	24797263
SFXN3_HUMAN	SFXN3	physical	24797263
UFL1_HUMAN	UFL1	physical	24797263
SUGP2_HUMAN	SUGP2	physical	24797263
ELP1_HUMAN	IKBKAP	physical	24797263
PDS5A_HUMAN	PDS5A	physical	24797263
TR10B_HUMAN	TNFRSF10B	physical	24797263
ACACA_HUMAN	ACACA	physical	24797263
HYOU1_HUMAN	HYOU1	physical	24797263
AT5F1_HUMAN	ATP5F1	physical	24797263
FLOT2_HUMAN	FLOT2	physical	24797263
NTPCR_HUMAN	NTPCR	physical	24797263
CERS2_HUMAN	CERS2	physical	24797263
ACOD_HUMAN	SCD	physical	24797263
QCR2_HUMAN	UQCRC2	physical	24797263
AT2B1_HUMAN	ATP2B1	physical	24797263
IF4G2_HUMAN	EIF4G2	physical	24797263
SAM50_HUMAN	SAMM50	physical	24797263
EMD_HUMAN	EMD	physical	24797263
XPO7_HUMAN	XPO7	physical	24797263
NUBP2_HUMAN	NUBP2	physical	24797263
DJC11_HUMAN	DNAJC11	physical	24797263
NCLN_HUMAN	NCLN	physical	24797263
SKIV2_HUMAN	SKIV2L	physical	24797263
RRP44_HUMAN	DIS3	physical	24797263
LSR_HUMAN	LSR	physical	24797263
A7L3B_HUMAN	ATXN7L3B	physical	24797263
EMC3_HUMAN	EMC3	physical	24797263
CALR_HUMAN	CALR	physical	24797263
PRI1_HUMAN	PRIM1	physical	24797263
MRM3_HUMAN	RNMTL1	physical	24797263
AAMP_HUMAN	AAMP	physical	24797263
ATD3B_HUMAN	ATAD3B	physical	24797263
RAB18_HUMAN	RAB18	physical	24797263
RL23_HUMAN	RPL23	physical	24797263
ANM3_HUMAN	PRMT3	physical	24797263
PDXD1_HUMAN	PDXDC1	physical	24797263
AAAS_HUMAN	AAAS	physical	24797263
SUCB1_HUMAN	SUCLA2	physical	24797263
IPO11_HUMAN	IPO11	physical	24797263
CTBP2_HUMAN	CTBP2	physical	24797263
KIF1A_HUMAN	KIF1A	physical	24797263
TPPC5_HUMAN	TRAPPC5	physical	24797263
ARMC6_HUMAN	ARMC6	physical	24797263
IMB1_HUMAN	KPNB1	physical	24797263
CMC2_HUMAN	SLC25A13	physical	24797263
SMC2_HUMAN	SMC2	physical	24797263
TBL3_HUMAN	TBL3	physical	24797263
SYIC_HUMAN	IARS	physical	24797263
CLUS_HUMAN	CLU	physical	24797263
ARHG2_HUMAN	ARHGEF2	physical	24797263
ATPA_HUMAN	ATP5A1	physical	24797263
RL22_HUMAN	RPL22	physical	24797263
FA98A_HUMAN	FAM98A	physical	24797263
IDH3A_HUMAN	IDH3A	physical	24797263
MMS19_HUMAN	MMS19	physical	24797263
DHC24_HUMAN	DHCR24	physical	24797263
FADS2_HUMAN	FADS2	physical	24797263
CKAP2_HUMAN	CKAP2	physical	24797263
SYFA_HUMAN	FARSA	physical	24797263
CEBPZ_HUMAN	CEBPZ	physical	24797263
TNPO3_HUMAN	TNPO3	physical	24797263
DSRAD_HUMAN	ADAR	physical	24797263
NU153_HUMAN	NUP153	physical	24797263
LPPRC_HUMAN	LRPPRC	physical	24797263
OPA1_HUMAN	OPA1	physical	24797263
STOM_HUMAN	STOM	physical	24797263
RFC4_HUMAN	RFC4	physical	24797263
TBG1_HUMAN	TUBG1	physical	24797263
LANC1_HUMAN	LANCL1	physical	24797263
TAF4_HUMAN	TAF4	physical	24797263
PSPC1_HUMAN	PSPC1	physical	24797263
EWS_HUMAN	EWSR1	physical	24797263
RBM10_HUMAN	RBM10	physical	24797263
AAMDC_HUMAN	AAMDC	physical	24797263
GRN_HUMAN	GRN	physical	24797263
PSMD1_HUMAN	PSMD1	physical	24797263
KT3K_HUMAN	FN3KRP	physical	24797263
TPM3_HUMAN	TPM3	physical	24797263
THOP1_HUMAN	THOP1	physical	24797263
CAP2_HUMAN	CAP2	physical	24797263
RL4_HUMAN	RPL4	physical	24797263
BLM_HUMAN	BLM	physical	24797263
PLST_HUMAN	PLS3	physical	24797263
BCLF1_HUMAN	BCLAF1	physical	24797263
TPM4_HUMAN	TPM4	physical	24797263
NT5D2_HUMAN	NT5DC2	physical	24797263
XRCC5_HUMAN	XRCC5	physical	24797263
H1X_HUMAN	H1FX	physical	24797263
RM09_HUMAN	MRPL9	physical	24797263
HS90A_HUMAN	HSP90AA1	physical	25402006
HSP7C_HUMAN	HSPA8	physical	25402006
PTN1_HUMAN	PTPN1	physical	25402006
SRC8_HUMAN	CTTN	physical	25402006
LAT_HUMAN	LAT	physical	25402006
HS90B_HUMAN	HSP90AB1	physical	25402006
HDAC6_HUMAN	HDAC6	physical	25402006
ZAP70_HUMAN	ZAP70	physical	25402006
SHC1_HUMAN	SHC1	physical	25402006
SRC_HUMAN	SRC	physical	25402006
KPCA_HUMAN	PRKCA	physical	25402006
CHIP_HUMAN	STUB1	physical	25402006
CRKL_HUMAN	CRKL	physical	25402006
GRB2_HUMAN	GRB2	physical	25402006
ANS1A_HUMAN	ANKS1A	physical	25402006
PGFRA_HUMAN	PDGFRA	physical	25402006
TNR1A_HUMAN	TNFRSF1A	physical	25402006
CSK_HUMAN	CSK	physical	25402006
NEMO_HUMAN	IKBKG	physical	25402006
SYUA_HUMAN	SNCA	physical	25402006
1433T_HUMAN	YWHAQ	physical	25402006
1433Z_HUMAN	YWHAZ	physical	25402006
1433B_HUMAN	YWHAB	physical	25402006
PDC6I_HUMAN	PDCD6IP	physical	25402006
STAT3_HUMAN	STAT3	physical	25402006
NRG1_HUMAN	NRG1	physical	25402006
TRAF2_HUMAN	TRAF2	physical	25402006
CAMLG_HUMAN	CAMLG	physical	25402006
LYN_HUMAN	LYN	physical	25402006
KPCE_HUMAN	PRKCE	physical	25402006
TAB1_HUMAN	TAB1	physical	25402006
1433S_HUMAN	SFN	physical	25402006
TAU_HUMAN	MAPT	physical	25402006
SHC4_HUMAN	SHC4	physical	25402006
DOK1_HUMAN	DOK1	physical	25402006
RAF1_HUMAN	RAF1	physical	25402006
BAIP2_HUMAN	BAIAP2	physical	25402006
SH23A_HUMAN	SH2D3A	physical	25402006
STAT1_HUMAN	STAT1	physical	25402006
ABL2_HUMAN	ABL2	physical	25402006
FGR_HUMAN	FGR	physical	25402006
SH3G2_HUMAN	SH3GL2	physical	25402006
BLK_HUMAN	BLK	physical	25402006
NCK2_HUMAN	NCK2	physical	25402006
ACTN4_HUMAN	ACTN4	physical	25402006
AKT1_HUMAN	AKT1	physical	25402006
FAK1_HUMAN	PTK2	physical	25402006
CRK_HUMAN	CRK	physical	25402006
PLCG2_HUMAN	PLCG2	physical	25402006
HCK_HUMAN	HCK	physical	25402006
RPGF1_HUMAN	RAPGEF1	physical	25402006
G3P_HUMAN	GAPDH	physical	25402006
SH3G3_HUMAN	SH3GL3	physical	25402006
MK08_HUMAN	MAPK8	physical	25402006
GCR_HUMAN	NR3C1	physical	25402006
GRB10_HUMAN	GRB10	physical	25402006
STA5A_HUMAN	STAT5A	physical	25402006
APBB2_HUMAN	APBB2	physical	25402006
CTND1_HUMAN	CTNND1	physical	25402006
SH2B1_HUMAN	SH2B1	physical	25402006
PTN22_HUMAN	PTPN22	physical	25402006
FRK_HUMAN	FRK	physical	25402006
SLAP1_HUMAN	SLA	physical	25402006
STAP2_HUMAN	STAP2	physical	25402006
ARRB1_HUMAN	ARRB1	physical	25402006
LCP2_HUMAN	LCP2	physical	25402006
PTN12_HUMAN	PTPN12	physical	25402006
ITB2_HUMAN	ITGB2	physical	25402006
EPS8_HUMAN	EPS8	physical	25402006
CAV2_HUMAN	CAV2	physical	25402006
TGFA_HUMAN	TGFA	physical	25402006
ARRB2_HUMAN	ARRB2	physical	25402006
KPCZ_HUMAN	PRKCZ	physical	25402006
HDAC7_HUMAN	HDAC7	physical	25402006
RET_HUMAN	RET	physical	25402006
SH2D3_HUMAN	SH2D3C	physical	25402006
SLAP2_HUMAN	SLA2	physical	25402006
CADH5_HUMAN	CDH5	physical	25402006
ITK_HUMAN	ITK	physical	25402006
NCK1_HUMAN	NCK1	physical	25402006
CADH1_HUMAN	CDH1	physical	25402006
MPIP3_HUMAN	CDC25C	physical	25402006
ITSN2_HUMAN	ITSN2	physical	25402006
M3K3_HUMAN	MAP3K3	physical	25402006
PIM1_HUMAN	PIM1	physical	25402006
ABL1_HUMAN	ABL1	physical	25402006
CAV1_HUMAN	CAV1	physical	25402006
GRAP2_HUMAN	GRAP2	physical	25402006
S10A4_HUMAN	S100A4	physical	25402006
SNX9_HUMAN	SNX9	physical	25402006
CDK1_HUMAN	CDK1	physical	25402006
SOCS3_HUMAN	SOCS3	physical	25402006
NTRK2_HUMAN	NTRK2	physical	25402006
P55G_HUMAN	PIK3R3	physical	25402006
PTN18_HUMAN	PTPN18	physical	25402006
JIP2_HUMAN	MAPK8IP2	physical	25402006
M4K1_HUMAN	MAP4K1	physical	25402006
PAK1_HUMAN	PAK1	physical	25402006
MK09_HUMAN	MAPK9	physical	25402006
VAV_HUMAN	VAV1	physical	25402006
WASL_HUMAN	WASL	physical	25402006
TENS3_HUMAN	TNS3	physical	25402006
WASF3_HUMAN	WASF3	physical	25402006
CISH_HUMAN	CISH	physical	25402006
ARHG7_HUMAN	ARHGEF7	physical	25402006
P3C2B_HUMAN	PIK3C2B	physical	25402006
SOCS6_HUMAN	SOCS6	physical	25402006
P85B_HUMAN	PIK3R2	physical	25402006
HSP74_HUMAN	HSPA4	physical	25402006
TBA1A_HUMAN	TUBA1A	physical	25402006
MUC1_HUMAN	MUC1	physical	25402006
PLAK_HUMAN	JUP	physical	25402006
GAB1_HUMAN	GAB1	physical	25402006
A4_HUMAN	APP	physical	25402006
LRP1_HUMAN	LRP1	physical	25402006
STAT2_HUMAN	STAT2	physical	25402006
TLR2_HUMAN	TLR2	physical	25402006
RGS4_HUMAN	RGS4	physical	25402006
SOS2_HUMAN	SOS2	physical	25402006
HGS_HUMAN	HGS	physical	25588945
CBL_HUMAN	CBL	physical	26055326
PIGS_HUMAN	PIGS	physical	26344197
P85B_HUMAN	PIK3R2	physical	1334406
PRKN_HUMAN	PARK2	physical	25877876
CTNA1_HUMAN	CTNNA1	physical	25241761
STAT3_HUMAN	STAT3	physical	25241761
ERBB2_HUMAN	ERBB2	physical	25241761
EGF_HUMAN	EGF	physical	25241761
P55G_HUMAN	PIK3R3	physical	25241761
FOS_HUMAN	FOS	physical	25241761
PLCG2_HUMAN	PLCG2	physical	25241761
P85A_HUMAN	PIK3R1	physical	25241761
CADH1_HUMAN	CDH1	physical	25241761
UBP8_HUMAN	USP8	physical	25485838
ABL1_HUMAN	ABL1	physical	24658140
ABL2_HUMAN	ABL2	physical	24658140
ACTN4_HUMAN	ACTN4	physical	24658140
AKT1_HUMAN	AKT1	physical	24658140
ANS1A_HUMAN	ANKS1A	physical	24658140
APBB2_HUMAN	APBB2	physical	24658140
A4_HUMAN	APP	physical	24658140
ARHG7_HUMAN	ARHGEF7	physical	24658140
ARRB1_HUMAN	ARRB1	physical	24658140
ARRB2_HUMAN	ARRB2	physical	24658140
BAIP2_HUMAN	BAIAP2	physical	24658140
BLK_HUMAN	BLK	physical	24658140
CAMLG_HUMAN	CAMLG	physical	24658140
CAV1_HUMAN	CAV1	physical	24658140
CAV2_HUMAN	CAV2	physical	24658140
MPIP3_HUMAN	CDC25C	physical	24658140
CADH1_HUMAN	CDH1	physical	24658140
CADH5_HUMAN	CDH5	physical	24658140
CDK1_HUMAN	CDK1	physical	24658140
CISH_HUMAN	CISH	physical	24658140
CRK_HUMAN	CRK	physical	24658140
CRKL_HUMAN	CRKL	physical	24658140
CSK_HUMAN	CSK	physical	24658140
CTND1_HUMAN	CTNND1	physical	24658140
SRC8_HUMAN	CTTN	physical	24658140
DOK1_HUMAN	DOK1	physical	24658140
EPS8_HUMAN	EPS8	physical	24658140
EZRI_HUMAN	EZR	physical	24658140
FGR_HUMAN	FGR	physical	24658140
FRK_HUMAN	FRK	physical	24658140
GAB1_HUMAN	GAB1	physical	24658140
G3P_HUMAN	GAPDH	physical	24658140
GRAP2_HUMAN	GRAP2	physical	24658140
GRB10_HUMAN	GRB10	physical	24658140
GRB2_HUMAN	GRB2	physical	24658140
HCK_HUMAN	HCK	physical	24658140
HDAC6_HUMAN	HDAC6	physical	24658140
HS90A_HUMAN	HSP90AA1	physical	24658140
HS90B_HUMAN	HSP90AB1	physical	24658140
HSP74_HUMAN	HSPA4	physical	24658140
HSP7C_HUMAN	HSPA8	physical	24658140
NEMO_HUMAN	IKBKG	physical	24658140
ITB2_HUMAN	ITGB2	physical	24658140
ITK_HUMAN	ITK	physical	24658140
ITSN2_HUMAN	ITSN2	physical	24658140
PLAK_HUMAN	JUP	physical	24658140
LAT_HUMAN	LAT	physical	24658140
LCP2_HUMAN	LCP2	physical	24658140
LRP1_HUMAN	LRP1	physical	24658140
LYN_HUMAN	LYN	physical	24658140
M3K3_HUMAN	MAP3K3	physical	24658140
M4K1_HUMAN	MAP4K1	physical	24658140
MK08_HUMAN	MAPK8	physical	24658140
JIP2_HUMAN	MAPK8IP2	physical	24658140
MK09_HUMAN	MAPK9	physical	24658140
TAU_HUMAN	MAPT	physical	24658140
MUC1_HUMAN	MUC1	physical	24658140
NCK1_HUMAN	NCK1	physical	24658140
NCK2_HUMAN	NCK2	physical	24658140
GCR_HUMAN	NR3C1	physical	24658140
NRG1_HUMAN	NRG1	physical	24658140
NTRK2_HUMAN	NTRK2	physical	24658140
PAK1_HUMAN	PAK1	physical	24658140
PDC6I_HUMAN	PDCD6IP	physical	24658140
PGFRA_HUMAN	PDGFRA	physical	24658140
P3C2B_HUMAN	PIK3C2B	physical	24658140
P85B_HUMAN	PIK3R2	physical	24658140
P55G_HUMAN	PIK3R3	physical	24658140
PIM1_HUMAN	PIM1	physical	24658140
PLCG2_HUMAN	PLCG2	physical	24658140
KPCA_HUMAN	PRKCA	physical	24658140
KPCE_HUMAN	PRKCE	physical	24658140
KPCZ_HUMAN	PRKCZ	physical	24658140
FAK1_HUMAN	PTK2	physical	24658140
PTN1_HUMAN	PTPN1	physical	24658140
PTN12_HUMAN	PTPN12	physical	24658140
PTN18_HUMAN	PTPN18	physical	24658140
PTN22_HUMAN	PTPN22	physical	24658140
RAF1_HUMAN	RAF1	physical	24658140
RPGF1_HUMAN	RAPGEF1	physical	24658140
RET_HUMAN	RET	physical	24658140
RGS4_HUMAN	RGS4	physical	24658140
S10A4_HUMAN	S100A4	physical	24658140
1433S_HUMAN	SFN	physical	24658140
SH2B1_HUMAN	SH2B1	physical	24658140
SH23A_HUMAN	SH2D3A	physical	24658140
SH2D3_HUMAN	SH2D3C	physical	24658140
SH3G2_HUMAN	SH3GL2	physical	24658140
SH3G3_HUMAN	SH3GL3	physical	24658140
SHC1_HUMAN	SHC1	physical	24658140
SHC4_HUMAN	SHC4	physical	24658140
SLAP1_HUMAN	SLA	physical	24658140
SLAP2_HUMAN	SLA2	physical	24658140
SYUA_HUMAN	SNCA	physical	24658140
SNX9_HUMAN	SNX9	physical	24658140
SOCS3_HUMAN	SOCS3	physical	24658140
SOCS6_HUMAN	SOCS6	physical	24658140
SOS2_HUMAN	SOS2	physical	24658140
SRC_HUMAN	SRC	physical	24658140
STAP2_HUMAN	STAP2	physical	24658140
STAT1_HUMAN	STAT1	physical	24658140
STAT2_HUMAN	STAT2	physical	24658140
STAT3_HUMAN	STAT3	physical	24658140
STA5A_HUMAN	STAT5A	physical	24658140
CHIP_HUMAN	STUB1	physical	24658140
TAB1_HUMAN	TAB1	physical	24658140
TGFA_HUMAN	TGFA	physical	24658140
TLR2_HUMAN	TLR2	physical	24658140
TNR1A_HUMAN	TNFRSF1A	physical	24658140
TENS3_HUMAN	TNS3	physical	24658140
TRAF2_HUMAN	TRAF2	physical	24658140
TBA1A_HUMAN	TUBA1A	physical	24658140
THIO_HUMAN	TXN	physical	24658140
VAV_HUMAN	VAV1	physical	24658140
WASF3_HUMAN	WASF3	physical	24658140
WASL_HUMAN	WASL	physical	24658140
1433B_HUMAN	YWHAB	physical	24658140
1433T_HUMAN	YWHAQ	physical	24658140
1433Z_HUMAN	YWHAZ	physical	24658140
ZAP70_HUMAN	ZAP70	physical	24658140
HDAC7_HUMAN	HDAC7	physical	24658140
PPARG_HUMAN	PPARG	physical	26718225
CBL_HUMAN	CBL	physical	25521828
KEAP1_HUMAN	KEAP1	physical	25628777
CBL_HUMAN	CBL	physical	26177020
CBL_HUMAN	CBL	physical	25872741
GRP78_HUMAN	HSPA5	physical	24189400
NELL1_HUMAN	NELL1	physical	24189400
SUSD1_HUMAN	SUSD1	physical	24189400
CYTA_HUMAN	CSTA	physical	24189400
GRP75_HUMAN	HSPA9	physical	24189400
AHNK_HUMAN	AHNAK	physical	24189400
ATPA_HUMAN	ATP5A1	physical	24189400
HSP7C_HUMAN	HSPA8	physical	24189400
AP2A1_HUMAN	AP2A1	physical	24189400
AP2B1_HUMAN	AP2B1	physical	24189400
ANO5_HUMAN	ANO5	physical	24189400
4F2_HUMAN	SLC3A2	physical	24189400
1433S_HUMAN	SFN	physical	24189400
ANXA1_HUMAN	ANXA1	physical	24189400
ARMC8_HUMAN	ARMC8	physical	24189400
BAIP2_HUMAN	BAIAP2	physical	24189400
COHA1_HUMAN	COL17A1	physical	24189400
CTNA1_HUMAN	CTNNA1	physical	24189400
CTNB1_HUMAN	CTNNB1	physical	24189400
CTND1_HUMAN	CTNND1	physical	24189400
CTNA2_HUMAN	CTNNA2	physical	24189400
CALX_HUMAN	CANX	physical	24189400
CADH1_HUMAN	CDH1	physical	24189400
HNRH1_HUMAN	HNRNPH1	physical	24189400
H2A1A_HUMAN	HIST1H2AA	physical	24189400
HSPB1_HUMAN	HSPB1	physical	24189400
H1X_HUMAN	H1FX	physical	24189400
PHLA1_HUMAN	PHLDA1	physical	24189400
RS15_HUMAN	RPS15	physical	24189400
RBM25_HUMAN	RBM25	physical	24189400
SPR1A_HUMAN	SPRR1A	physical	24189400
SPB4_HUMAN	SERPINB4	physical	24189400
SRAC1_HUMAN	SERAC1	physical	24189400
SFPQ_HUMAN	SFPQ	physical	24189400
PTPRD_HUMAN	PTPRD	physical	24189400
PTPRF_HUMAN	PTPRF	physical	24189400
MET_HUMAN	MET	physical	24189400
ITB4_HUMAN	ITGB4	physical	24189400
ERBB2_HUMAN	ERBB2	physical	24189400
1A02_HUMAN	HLA-A	physical	24189400
1A03_HUMAN	HLA-A	physical	24189400
1A01_HUMAN	HLA-A	physical	24189400
1A26_HUMAN	HLA-A	physical	24189400
XRN2_HUMAN	XRN2	physical	24189400
SGPL1_HUMAN	SGPL1	physical	24189400
GSTT1_HUMAN	GSTT1	physical	24189400
DBR1_HUMAN	DBR1	physical	24189400
AP1B1_HUMAN	AP1B1	physical	24189400
AP2A2_HUMAN	AP2A2	physical	24189400
AP2M1_HUMAN	AP2M1	physical	24189400
AP2S1_HUMAN	AP2S1	physical	24189400
LAT1_HUMAN	SLC7A5	physical	24189400
VP13A_HUMAN	VPS13A	physical	24189400
YTHD1_HUMAN	YTHDF1	physical	24189400
RL17_HUMAN	RPL17	physical	24189400
AT2B4_HUMAN	ATP2B4	physical	24189400
AT2A2_HUMAN	ATP2A2	physical	24189400
APOB_HUMAN	APOB	physical	24189400
UBS3B_HUMAN	UBASH3B	physical	24189400
ERRFI_HUMAN	ERRFI1	physical	24189400
ERBB3_HUMAN	ERBB3	physical	24189400
SHC1_HUMAN	SHC1	physical	24189400
CDC37_HUMAN	CDC37	physical	24189400
STAT3_HUMAN	STAT3	physical	24189400
SRC_HUMAN	SRC	physical	24189400
ERBB2_HUMAN	ERBB2	physical	20211985
ACTB_HUMAN	ACTB	physical	22366308
MYH9_HUMAN	MYH9	physical	22366308
CBL_HUMAN	CBL	physical	27059931
GRB2_HUMAN	GRB2	physical	27059931
IQGA1_HUMAN	IQGAP1	physical	19114553
CD44_HUMAN	CD44	physical	15597342
EGFR_HUMAN	EGFR	physical	8870675
NIBL1_HUMAN	FAM129B	physical	26721396
ERRFI_HUMAN	ERRFI1	physical	26280531
EGF_HUMAN	EGF	physical	25080504
TGFA_HUMAN	TGFA	physical	12297049
EGFR_HUMAN	EGFR	physical	12297049
EGF_HUMAN	EGF	physical	12297050
EGFR_HUMAN	EGFR	physical	12297050
EGF_HUMAN	EGF	physical	12620237
EGFR_HUMAN	EGFR	physical	12620237
EGFR_HUMAN	EGFR	physical	25453753
EGF_HUMAN	EGF	physical	25453753
BBC3B_HUMAN	BBC3	physical	20153921
BBC3_HUMAN	BBC3	physical	20153921
PLCG1_BOVIN	PLCG1	physical	2732223
PLCB1_BOVIN	PLCB1	physical	2732223
EGFR_HUMAN	EGFR	physical	2732223
GSTP1_HUMAN	GSTP1	physical	26429914
RAD_HUMAN	RRAD	physical	25313011
PTN1_HUMAN	PTPN1	physical	7693694
EGF_HUMAN	EGF	physical	26280537
MIF_HUMAN	MIF	physical	26280537
SH3G2_HUMAN	SH3GL2	physical	24854121
ERCC1_HUMAN	ERCC1	physical	24780295
XPF_HUMAN	ERCC4	physical	24780295
CLCN5_HUMAN	CLCN5	physical	24780295
MCM4_HUMAN	MCM4	physical	24780295
APEX1_HUMAN	APEX1	physical	24780295
NUCL_HUMAN	NCL	physical	24780295
NPM_HUMAN	NPM1	physical	24780295
PARP1_HUMAN	PARP1	physical	24780295
LMNA_HUMAN	LMNA	physical	24780295
FUS_HUMAN	FUS	physical	24780295
ERCC2_HUMAN	ERCC2	physical	24780295
TIF1B_HUMAN	TRIM28	physical	24780295
XRN2_HUMAN	XRN2	physical	24780295
MCM3_HUMAN	MCM3	physical	24780295
MCM6_HUMAN	MCM6	physical	24780295
FEN1_HUMAN	FEN1	physical	24780295
ILF2_HUMAN	ILF2	physical	24780295
ILF3_HUMAN	ILF3	physical	24780295
DHX9_HUMAN	DHX9	physical	24780295
BABA2_HUMAN	BRE	physical	24780295
TOP1_HUMAN	TOP1	physical	24780295
LTK_HUMAN	LTK	physical	7650032
GRB2_HUMAN	GRB2	physical	7650032
EGFR_HUMAN	EGFR	physical	23794705
IBP2_HUMAN	IGFBP2	physical	25893308
CBL_HUMAN	CBL	physical	28198003
EGFR_HUMAN	EGFR	physical	21775422
CADH2_HUMAN	CDH2	physical	19033391
GRB2_HUMAN	GRB2	physical	8810340
SHC1_HUMAN	SHC1	physical	8810340
ITB1_HUMAN	ITGB1	physical	23595626
EGFR_HUMAN	EGFR	physical	23595626
EGFR_HUMAN	EGFR	physical	20456371
STAT3_HUMAN	STAT3	physical	18258752
SHC1_HUMAN	SHC1	physical	28065597
PTN12_HUMAN	PTPN12	physical	28065597
PTPRR_HUMAN	PTPRR	physical	28065597
PTN11_HUMAN	PTPN11	physical	28065597
PTN6_HUMAN	PTPN6	physical	28065597
PTN7_HUMAN	PTPN7	physical	28065597
PTPRA_HUMAN	PTPRA	physical	28065597
PTPRB_HUMAN	PTPRB	physical	28065597
PTPRT_HUMAN	PTPRT	physical	28065597
PPM1A_HUMAN	PPM1A	physical	28065597
PPM1F_HUMAN	PPM1F	physical	28065597
DUS14_HUMAN	DUSP14	physical	28065597
DUS18_HUMAN	DUSP18	physical	28065597
MPZL2_HUMAN	MPZL2	physical	28065597
SSH1_HUMAN	SSH1	physical	28065597
SRC_HUMAN	SRC	physical	28065597
F186A_HUMAN	FAM186A	physical	28065597
SRRM4_HUMAN	SRRM4	physical	28065597
CLM7_HUMAN	CD300LB	physical	28065597
KR161_HUMAN	KRTAP16-1	physical	28065597
MYO9A_HUMAN	MYO9A	physical	28065597
BTBDI_HUMAN	BTBD18	physical	28065597
IGLL5_HUMAN	IGLL5	physical	28065597
RAS4B_HUMAN	RASA4B	physical	28065597
PGRC1_HUMAN	PGRMC1	physical	28065597
SPT5H_HUMAN	SUPT5H	physical	28065597
ACACB_HUMAN	ACACB	physical	28065597
TRAD1_HUMAN	TRAFD1	physical	28065597
IF1AY_HUMAN	EIF1AY	physical	28065597
SC16A_HUMAN	SEC16A	physical	28065597
ZBT22_HUMAN	ZBTB22	physical	28065597
SPTC1_HUMAN	SPTLC1	physical	28065597
PMM2_HUMAN	PMM2	physical	28065597
E41L2_HUMAN	EPB41L2	physical	28065597
FOXO3_HUMAN	FOXO3	physical	28065597
HTSF1_HUMAN	HTATSF1	physical	28065597
DYRK3_HUMAN	DYRK3	physical	28065597
ZBT14_HUMAN	ZBTB14	physical	28065597
DHX16_HUMAN	DHX16	physical	28065597
CE104_HUMAN	CEP104	physical	28065597
IF2P_HUMAN	EIF5B	physical	28065597
NPHP4_HUMAN	NPHP4	physical	28065597
DJC13_HUMAN	DNAJC13	physical	28065597
SPAG7_HUMAN	SPAG7	physical	28065597
TOM70_HUMAN	TOMM70A	physical	28065597
SLIK3_HUMAN	SLITRK3	physical	28065597
OR2F2_HUMAN	OR2F2	physical	28065597
LC7L3_HUMAN	LUC7L3	physical	28065597
LCA5L_HUMAN	LCA5L	physical	28065597
ABCA1_HUMAN	ABCA1	physical	28065597
HERC2_HUMAN	HERC2	physical	28065597
PAK4_HUMAN	PAK4	physical	28065597
DYR_HUMAN	DHFR	physical	28065597
EGFR_HUMAN	EGFR	physical	28065597
1B07_HUMAN	HLA-B	physical	28065597
1B18_HUMAN	HLA-B	physical	28065597
CO1A1_HUMAN	COL1A1	physical	28065597
FETUA_HUMAN	AHSG	physical	28065597
ESR1_HUMAN	ESR1	physical	28065597
MAS_HUMAN	MAS1	physical	28065597
K2C1_HUMAN	KRT1	physical	28065597
AT1A1_HUMAN	ATP1A1	physical	28065597
HMGN2_HUMAN	HMGN2	physical	28065597
RLA2_HUMAN	RPLP2	physical	28065597
LA_HUMAN	SSB	physical	28065597
CATD_HUMAN	CTSD	physical	28065597
HSP7C_HUMAN	HSPA8	physical	28065597
CO1A2_HUMAN	COL1A2	physical	28065597
K1C16_HUMAN	KRT16	physical	28065597
HMGB1_HUMAN	HMGB1	physical	28065597
PARP1_HUMAN	PARP1	physical	28065597
ZCC18_HUMAN	ZCCHC18	physical	28065597
GRP78_HUMAN	HSPA5	physical	28065597
DRD2_HUMAN	DRD2	physical	28065597
ENPL_HUMAN	HSP90B1	physical	28065597
GLNA_HUMAN	GLUL	physical	28065597
H2AX_HUMAN	H2AFX	physical	28065597
HMGA1_HUMAN	HMGA1	physical	28065597
DDX5_HUMAN	DDX5	physical	28065597
TCPA_HUMAN	TCP1	physical	28065597
RL7_HUMAN	RPL7	physical	28065597
LFA3_HUMAN	CD58	physical	28065597
NUCL_HUMAN	NCL	physical	28065597
NF1_HUMAN	NF1	physical	28065597
PPIB_HUMAN	PPIB	physical	28065597
RS3_HUMAN	RPS3	physical	28065597
IF4B_HUMAN	EIF4B	physical	28065597
TENA_HUMAN	TNC	physical	28065597
PSA3_HUMAN	PSMA3	physical	28065597
PSA4_HUMAN	PSMA4	physical	28065597
U2AF2_HUMAN	U2AF2	physical	28065597
CNTF_HUMAN	CNTF	physical	28065597
HMGB2_HUMAN	HMGB2	physical	28065597
EF1G_HUMAN	EEF1G	physical	28065597
DPP4_HUMAN	DPP4	physical	28065597
APEX1_HUMAN	APEX1	physical	28065597
MAP4_HUMAN	MAP4	physical	28065597
CALX_HUMAN	CANX	physical	28065597
DHI1_HUMAN	HSD11B1	physical	28065597
RPB1_HUMAN	POLR2A	physical	28065597
GBRA3_HUMAN	GABRA3	physical	28065597
K1C9_HUMAN	KRT9	physical	28065597
TRI23_HUMAN	TRIM23	physical	28065597
LONM_HUMAN	LONP1	physical	28065597
GRP75_HUMAN	HSPA9	physical	28065597
RL3_HUMAN	RPL3	physical	28065597
RS27_HUMAN	RPS27	physical	28065597
GRIK4_HUMAN	GRIK4	physical	28065597
EFTU_HUMAN	TUFM	physical	28065597
AL7A1_HUMAN	ALDH7A1	physical	28065597
RBM25_HUMAN	RBM25	physical	28065597
EMD_HUMAN	EMD	physical	28065597
RL14_HUMAN	RPL14	physical	28065597
IDH3G_HUMAN	IDH3G	physical	28065597
IRAK1_HUMAN	IRAK1	physical	28065597
KCNQ1_HUMAN	KCNQ1	physical	28065597
HDGF_HUMAN	HDGF	physical	28065597
BTAF1_HUMAN	BTAF1	physical	28065597
TCP4_HUMAN	SUB1	physical	28065597
RAD_HUMAN	RRAD	physical	28065597
XPO2_HUMAN	CSE1L	physical	28065597
MFAP1_HUMAN	MFAP1	physical	28065597
EIF3B_HUMAN	EIF3B	physical	28065597
SESN2_HUMAN	SESN2	physical	28065597
KR109_HUMAN	KRTAP10-9	physical	28065597
RS20_HUMAN	RPS20	physical	28065597
S10AA_HUMAN	S100A10	physical	28065597
HNRPK_HUMAN	HNRNPK	physical	28065597
CNBP_HUMAN	CNBP	physical	28065597
RAB1A_HUMAN	RAB1A	physical	28065597
TRA2B_HUMAN	TRA2B	physical	28065597
YBOX1_HUMAN	YBX1	physical	28065597
IF4G2_HUMAN	EIF4G2	physical	28065597
NTH_HUMAN	NTHL1	physical	28065597
XIAP_HUMAN	XIAP	physical	28065597
RBM10_HUMAN	RBM10	physical	28065597
SRSF2_HUMAN	SRSF2	physical	28065597
AK17A_HUMAN	AKAP17A	physical	28065597
RL6_HUMAN	RPL6	physical	28065597
SRS11_HUMAN	SRSF11	physical	28065597
SLC31_HUMAN	SLC3A1	physical	28065597
LRP1_HUMAN	LRP1	physical	28065597
SSRP1_HUMAN	SSRP1	physical	28065597
RGF1B_HUMAN	RASGEF1B	physical	28065597
TM267_HUMAN	C5orf28	physical	28065597
KIF1A_HUMAN	KIF1A	physical	28065597
BPTF_HUMAN	BPTF	physical	28065597
CSTF3_HUMAN	CSTF3	physical	28065597
G3BP1_HUMAN	G3BP1	physical	28065597
TCOF_HUMAN	TCOF1	physical	28065597
HAP28_HUMAN	PDAP1	physical	28065597
VPP3_HUMAN	TCIRG1	physical	28065597
HDAC1_HUMAN	HDAC1	physical	28065597
CDK13_HUMAN	CDK13	physical	28065597
CIRBP_HUMAN	CIRBP	physical	28065597
LRP8_HUMAN	LRP8	physical	28065597
PDE1C_HUMAN	PDE1C	physical	28065597
UBP2L_HUMAN	UBAP2L	physical	28065597
CAPR1_HUMAN	CAPRIN1	physical	28065597
RBM39_HUMAN	RBM39	physical	28065597
DIP2A_HUMAN	DIP2A	physical	28065597
CBX2_HUMAN	CBX2	physical	28065597
GRM4_HUMAN	GRM4	physical	28065597
STIL_HUMAN	STIL	physical	28065597
DIXC1_HUMAN	DIXDC1	physical	28065597
HERC1_HUMAN	HERC1	physical	28065597
E2F4_HUMAN	E2F4	physical	28065597
MICB_HUMAN	MICB	physical	28065597
P3H1_HUMAN	P3H1	physical	28065597
LRRK1_HUMAN	LRRK1	physical	28065597
KR151_HUMAN	KRTAP15-1	physical	28065597
PTN20_HUMAN	PTPN20B	physical	28065597
ACSF4_HUMAN	AASDH	physical	28065597
RHG29_HUMAN	ARHGAP29	physical	28065597
FBLN7_HUMAN	FBLN7	physical	28065597
S45A4_HUMAN	SLC45A4	physical	28065597
DOP1_HUMAN	DOPEY1	physical	28065597
CE170_HUMAN	CEP170	physical	28065597
EYS_HUMAN	EYS	physical	28065597
SWT1_HUMAN	SWT1	physical	28065597
SKT_HUMAN	KIAA1217	physical	28065597
MCAF2_HUMAN	ATF7IP2	physical	28065597
ZMYM4_HUMAN	ZMYM4	physical	28065597
EST4A_HUMAN	CES4A	physical	28065597
WWC2_HUMAN	WWC2	physical	28065597
H2A2A_HUMAN	HIST2H2AA3	physical	28065597
NADE_HUMAN	NADSYN1	physical	28065597
PKHA7_HUMAN	PLEKHA7	physical	28065597
MAST2_HUMAN	MAST2	physical	28065597
ARMX5_HUMAN	ARMCX5	physical	28065597
XRRA1_HUMAN	XRRA1	physical	28065597
SCYL2_HUMAN	SCYL2	physical	28065597
GGYF2_HUMAN	GIGYF2	physical	28065597
EMAL6_HUMAN	EML6	physical	28065597
UBP34_HUMAN	USP34	physical	28065597
UBP31_HUMAN	USP31	physical	28065597
CYS1_HUMAN	CYS1	physical	28065597
SMIM5_HUMAN	SMIM5	physical	28065597
RSRC2_HUMAN	RSRC2	physical	28065597
ZCCHV_HUMAN	ZC3HAV1	physical	28065597
PCLI1_HUMAN	PID1	physical	28065597
SETX_HUMAN	SETX	physical	28065597
OR2W3_HUMAN	OR2W3	physical	28065597
PRS42_HUMAN	PRSS42	physical	28065597
NEK8_HUMAN	NEK8	physical	28065597
LRRT4_HUMAN	LRRTM4	physical	28065597
HEAT4_HUMAN	HEATR4	physical	28065597
ZN573_HUMAN	ZNF573	physical	28065597
S13A5_HUMAN	SLC13A5	physical	28065597
HORN_HUMAN	HRNR	physical	28065597
CCD60_HUMAN	CCDC60	physical	28065597
F126B_HUMAN	FAM126B	physical	28065597
SRRM1_HUMAN	SRRM1	physical	28065597
CC146_HUMAN	CCDC146	physical	28065597
ZZZ3_HUMAN	ZZZ3	physical	28065597
CENPL_HUMAN	CENPL	physical	28065597
MIER1_HUMAN	MIER1	physical	28065597
UNC80_HUMAN	UNC80	physical	28065597
EFCB3_HUMAN	EFCAB3	physical	28065597
TRIMM_HUMAN	TRIML2	physical	28065597
STPG4_HUMAN	C2orf61	physical	28065597
RM43_HUMAN	MRPL43	physical	28065597
TOPZ1_HUMAN	TOPAZ1	physical	28065597
ZN114_HUMAN	ZNF114	physical	28065597
PAIRB_HUMAN	SERBP1	physical	28065597
LS14A_HUMAN	LSM14A	physical	28065597
CTCFL_HUMAN	CTCFL	physical	28065597
BBS10_HUMAN	BBS10	physical	28065597
MK15_HUMAN	MAPK15	physical	28065597
CHD6_HUMAN	CHD6	physical	28065597
MIPT3_HUMAN	TRAF3IP1	physical	28065597
UTP15_HUMAN	UTP15	physical	28065597
HEXDC_HUMAN	HEXDC	physical	28065597
LMBR1_HUMAN	LMBR1	physical	28065597
KBTB7_HUMAN	KBTBD7	physical	28065597
MUC16_HUMAN	MUC16	physical	28065597
DYH7_HUMAN	DNAH7	physical	28065597
TITIN_HUMAN	TTN	physical	28065597
ROBO4_HUMAN	ROBO4	physical	28065597
S39A7_HUMAN	SLC39A7	physical	28065597
GBF1_HUMAN	GBF1	physical	28065597
EDEM1_HUMAN	EDEM1	physical	28065597
ZN516_HUMAN	ZNF516	physical	28065597
PRP16_HUMAN	DHX38	physical	28065597
DAZL_HUMAN	DAZL	physical	28065597
LFG3_HUMAN	TMBIM1	physical	28065597
TM159_HUMAN	TMEM159	physical	28065597
DOC10_HUMAN	DOCK10	physical	28065597
MTBP_HUMAN	MTBP	physical	28065597
ELP4_HUMAN	ELP4	physical	28065597
MTMR8_HUMAN	MTMR8	physical	28065597
RN125_HUMAN	RNF125	physical	28065597
DYH8_HUMAN	DNAH8	physical	28065597
SCYL1_HUMAN	SCYL1	physical	28065597
ZFR_HUMAN	ZFR	physical	28065597
PRIC1_HUMAN	PRICKLE1	physical	28065597
RUN3B_HUMAN	RUNDC3B	physical	28065597
SPB12_HUMAN	SERPINB12	physical	28065597
SMG1_HUMAN	SMG1	physical	28065597
PCX1_HUMAN	PCNX	physical	28065597
MINT_HUMAN	SPEN	physical	28065597
TS101_HUMAN	TSG101	physical	28065597
SPAG8_HUMAN	SPAG8	physical	28065597
SOSB1_HUMAN	NABP2	physical	28065597
ZFY21_HUMAN	ZFYVE21	physical	28065597
SYT17_HUMAN	SYT17	physical	28065597
CNPY3_HUMAN	CNPY3	physical	28065597
MTG1_HUMAN	MTG1	physical	28065597
ASHWN_HUMAN	C2orf49	physical	28065597
PRR14_HUMAN	PRR14	physical	28065597
PLVAP_HUMAN	PLVAP	physical	28065597
API5_HUMAN	API5	physical	28065597
NXF2_HUMAN	NXF2	physical	28065597
KTBL1_HUMAN	KATNBL1	physical	28065597
SPC1L_HUMAN	SPATC1L	physical	28065597
NUCKS_HUMAN	NUCKS1	physical	28065597
RWDD1_HUMAN	RWDD1	physical	28065597
DPEP3_HUMAN	DPEP3	physical	28065597
REEP4_HUMAN	REEP4	physical	28065597
NOL6_HUMAN	NOL6	physical	28065597
RPF1_HUMAN	RPF1	physical	28065597
SNX29_HUMAN	SNX29	physical	28065597
TRPM3_HUMAN	TRPM3	physical	28065597
IRPL2_HUMAN	IL1RAPL2	physical	28065597
MLXPL_HUMAN	MLXIPL	physical	28065597
RAB18_HUMAN	RAB18	physical	28065597
INCE_HUMAN	INCENP	physical	28065597
EXOS3_HUMAN	EXOSC3	physical	28065597
SRTD4_HUMAN	SERTAD4	physical	28065597
RNF12_HUMAN	RLIM	physical	28065597
GPTC2_HUMAN	GPATCH2	physical	28065597
BCLF1_HUMAN	BCLAF1	physical	28065597
RCC2_HUMAN	RCC2	physical	28065597
HECW2_HUMAN	HECW2	physical	28065597
CRCT1_HUMAN	CRCT1	physical	28065597
TMEM2_HUMAN	TMEM2	physical	28065597
TEKT2_HUMAN	TEKT2	physical	28065597
SO3A1_HUMAN	SLCO3A1	physical	28065597
RABX5_HUMAN	RABGEF1	physical	28065597
ERRFI_HUMAN	ERRFI1	physical	28065597
JUPI1_HUMAN	HN1	physical	28065597
TNIK_HUMAN	TNIK	physical	28065597
GPTC8_HUMAN	GPATCH8	physical	28065597
TRHDE_HUMAN	TRHDE	physical	28065597
BAG5_HUMAN	BAG5	physical	28065597
GRID1_HUMAN	GRID1	physical	28065597
S45A2_HUMAN	SLC45A2	physical	28065597
MAGD2_HUMAN	MAGED2	physical	28065597
ING4_HUMAN	ING4	physical	28065597
ZC3H4_HUMAN	ZC3H4	physical	28065597
CBPC1_HUMAN	AGTPBP1	physical	28065597
SHAN2_HUMAN	SHANK2	physical	28065597
SRRM2_HUMAN	SRRM2	physical	28065597
RUVB2_HUMAN	RUVBL2	physical	28065597
COA3_HUMAN	COA3	physical	28065597
NOSIP_HUMAN	NOSIP	physical	28065597
CBY1_HUMAN	CBY1	physical	28065597
WIPI2_HUMAN	WIPI2	physical	28065597
PCDG3_HUMAN	PCDHGA3	physical	28065597
K2C3_HUMAN	KRT3	physical	28065597
K1C10_HUMAN	KRT10	physical	28065597
K22E_HUMAN	KRT2	physical	28065597
K2C5_HUMAN	KRT5	physical	28065597
APOB_HUMAN	APOB	physical	28065597
GOGB1_HUMAN	GOLGB1	physical	28065597
GP149_HUMAN	GPR149	physical	28065597
PP2BB_HUMAN	PPP3CB	physical	28065597
PPM1B_HUMAN	PPM1B	physical	28065597
ILKAP_HUMAN	ILKAP	physical	28065597
DUS19_HUMAN	DUSP19	physical	28065597
STYX_HUMAN	STYX	physical	28065597
EGFR_HUMAN	EGFR	physical	24135280
STAT3_HUMAN	STAT3	physical	24135280
STA5A_HUMAN	STAT5A	physical	24135280
EGFR_HUMAN	EGFR	physical	24077285
STA5B_HUMAN	STAT5B	physical	22729867
STA5A_HUMAN	STAT5A	physical	22729867
EGF_HUMAN	EGF	physical	22729867
HBEGF_HUMAN	HBEGF	physical	15358134
PTN11_HUMAN	PTPN11	physical	20473329
SOS1_HUMAN	SOS1	physical	20473329
GRB2_HUMAN	GRB2	physical	20473329
SHC1_HUMAN	SHC1	physical	20473329
GSTP1_HUMAN	GSTP1	physical	19254954
GRB2_HUMAN	GRB2	physical	19254954
P53_HUMAN	TP53	genetic	27438146
GAB1_HUMAN	GAB1	physical	9890893
EGFR_HUMAN	EGFR	physical	11087732
EGFR_HUMAN	EGFR	physical	6321473
CHIP_HUMAN	STUB1	physical	27475501
PTN11_HUMAN	PTPN11	physical	8959326
GPNMB_HUMAN	GPNMB	physical	26751287
RGS16_HUMAN	RGS16	physical	11602604
RGS2_HUMAN	RGS2	physical	11602604
RGS4_HUMAN	RGS4	physical	11602604
EGFR_MOUSE	Egfr	physical	2915986
EGFR_HUMAN	EGFR	physical	2915986
MUC1_HUMAN	MUC1	physical	11278868
PLCG1_HUMAN	PLCG1	physical	19605547
COX2_HUMAN	COX2	physical	15282306
GAB1_HUMAN	GAB1	physical	23066441
ACK1_HUMAN	TNK2	physical	20359967
EGFR_HUMAN	EGFR	physical	19560417

Drug and Disease Associations

• Kegg Disease
• H00016: Oral cancer
• H00017: Esophageal cancer
• H00018: Gastric cancer
• H00022: Bladder cancer
• H00028: Choriocarcinoma
• H00030: Cervical cancer
• H00042: Glioma
• H00055: Laryngeal cancer
• OMIM Disease
• 211980: Lung cancer (LNCR)
• 616069: Inflammatory skin and bowel disease, neonatal, 2 (NISBD2)
• Kegg Drug
• D01977: Gefitinib (JAN/USAN/INN); Iressa (TN)
• D03350: Canertinib dihydrochloride (USAN)
• D03455: Cetuximab (genetical recombination) (JAN); Cetuximab (USAN/INN); Erbitux (TN)
• D04023: Erlotinib hydrochloride (JAN/USAN); Tarceva (TN)
• D04024: Lapatinib tosilate hydrate (JAN); Lapatinib ditosylate (USAN); Tykerb (TN)
• D05350: Panitumumab (genetical recombination) (JAN); Panitumumab (USAN/INN); Vectibix (TN)
• D05399: Pelitinib (USAN/INN)
• D06407: Vandetanib (JAN/USAN/INN); Caprelsa (TN)
• D07907: Erlotinib (INN); Tarceva (TN)
• D08108: Lapatinib (INN)
• D08950: Neratinib (INN/USAN)
• D09689: Varlitinib (USAN/INN)
• D09690: Varlitinib tosylate (USAN)
• D09724: Afatinib (USAN/INN)
• D09733: Afatinib maleate (JAN); Afatinib dimaleate (USAN)
• D09883: Dacomitinib (USAN/INN)
• D10018: Necitumumab (USAN/INN)
• D10031: Zalutumumab (USAN/INN)
• D10439: Imgatuzumab (USAN/INN)
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Methylation

"Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylationnegatively modulates EGFR-mediated ERK activation.";
Hsu J.M., Chen C.T., Chou C.K., Kuo H.P., Li L.Y., Lin C.Y., Lee H.J.,Wang Y.N., Liu M., Liao H.W., Shi B., Lai C.C., Bedford M.T.,Tsai C.H., Hung M.C.;
Nat. Cell Biol. 13:174-181(2011).
Cited for: FUNCTION IN CELL PROLIFERATION AND CELL MIGRATION, METHYLATION ATARG-1199 BY PRMT5, AND INTERACTION WITH PRMT5 AND PTPN6.
PubMed: 21258366

N-linked Glycosylation

"Structural evidence for loose linkage between ligand binding andkinase activation in the epidermal growth factor receptor.";
Lu C., Mi L.Z., Grey M.J., Zhu J., Graef E., Yokoyama S.,Springer T.A.;
Mol. Cell. Biol. 30:5432-5443(2010).
Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF 25-638 IN COMPLEX WITH EGF,FUNCTION, SUBUNIT, DISULFIDE BONDS, AND GLYCOSYLATION AT ASN-56;ASN-73; ASN-175; ASN-196; ASN-352; ASN-361; ASN-444 AND ASN-528.
PubMed: 20837704

"EGF activates its receptor by removing interactions that autoinhibitectodomain dimerization.";
Ferguson K.M., Berger M.B., Mendrola J.M., Cho H.S., Leahy D.J.,Lemmon M.A.;
Mol. Cell 11:507-517(2003).
Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 25-642 IN COMPLEX WITH EGF,FUNCTION, SUBUNIT, MUTAGENESIS OF 587-ASP--HIS-590 AND LYS-609,DISULFIDE BONDS, AND GLYCOSYLATION AT ASN-352; ASN-361; ASN-444;ASN-528; ASN-568 AND ASN-603.
PubMed: 12620237

"Crystal structure of the complex of human epidermal growth factor andreceptor extracellular domains.";
Ogiso H., Ishitani R., Nureki O., Fukai S., Yamanaka M., Kim J.H.,Saito K., Sakamoto A., Inoue M., Shirouzu M., Yokoyama S.;
Cell 110:775-787(2002).
Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF 25-646 IN COMPLEX WITH EGF,FUNCTION IN MAPK1 AND/OR MAPK3 ACTIVATION, SUBUNIT, SUBCELLULARLOCATION, MUTAGENESIS OF TYR-275; PHE-287; ARG-309 AND ARG-429,DISULFIDE BONDS, AND GLYCOSYLATION AT ASN-56; ASN-175; ASN-196;ASN-352; ASN-361 AND ASN-444.
PubMed: 12297050

"Glycoproteomics analysis of human liver tissue by combination ofmultiple enzyme digestion and hydrazide chemistry.";
Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.;
J. Proteome Res. 8:651-661(2009).
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-352; ASN-413 AND ASN-568,AND MASS SPECTROMETRY.
PubMed: 19159218

"Extended Range Proteomic Analysis (ERPA): a new and sensitive LC-MSplatform for high sequence coverage of complex proteins with extensivepost-translational modifications-comprehensive analysis of beta-caseinand epidermal growth factor receptor (EGFR).";
Wu S.L., Kim J., Hancock W.S., Karger B.;
J. Proteome Res. 4:1155-1170(2005).
Cited for: GLYCOSYLATION AT ASN-56; ASN-128; ASN-175; ASN-196; ASN-352; ASN-361;ASN-413; ASN-444; ASN-528; ASN-568 AND ASN-603, PHOSPHORYLATION ATTHR-693; SER-991 AND SER-1026, AND MASS SPECTROMETRY.
PubMed: 16083266

"Characterization of the N-oligosaccharides attached to the atypicalAsn-X-Cys sequence of recombinant human epidermal growth factorreceptor.";
Sato C., Kim J.-H., Abe Y., Saito K., Yokoyama S., Kohda D.;
J. Biochem. 127:65-72(2000).
Cited for: GLYCOSYLATION AT ASN-56; ASN-352; ASN-361; ASN-568 AND ASN-603.
PubMed: 10731668

"Analysis of the glycosylation patterns of the extracellular domain ofthe epidermal growth factor receptor expressed in Chinese hamsterovary fibroblasts.";
Smith K.D., Davies M.J., Bailey D., Renouf D.V., Hounsell E.F.;
Growth Factors 13:121-132(1996).
Cited for: GLYCOSYLATION AT ASN-128; ASN-175; ASN-413; ASN-444 AND ASN-528.
PubMed: 8962717

Phosphorylation

"Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant proteinexpression in gefitinib-resistant cells.";
Huang W.C., Chen Y.J., Li L.Y., Wei Y.L., Hsu S.C., Tsai S.L.,Chiu P.C., Huang W.P., Wang Y.N., Chen C.H., Chang W.C., Chang W.C.,Chen A.J., Tsai C.H., Hung M.C.;
J. Biol. Chem. 286:20558-20568(2011).
Cited for: PHOSPHORYLATION AT SER-229.
PubMed: 21487020

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-693; SER-695; SER-991;THR-993; SER-995; TYR-998; SER-1039; THR-1041; SER-1042; SER-1045;SER-1064 AND SER-1166, AND MASS SPECTROMETRY.
PubMed: 18669648

"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle.";
Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.;
Mol. Cell 31:438-448(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-693; SER-695; THR-725;SER-991; SER-1025; SER-1026; SER-1037; SER-1039; SER-1042; SER-1064;SER-1081; SER-1166 AND TYR-1197, AND MASS SPECTROMETRY.
PubMed: 18691976

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-693 AND SER-991, ANDMASS SPECTROMETRY.
PubMed: 18220336

"Multiple reaction monitoring for robust quantitative proteomicanalysis of cellular signaling networks.";
Wolf-Yadlin A., Hautaniemi S., Lauffenburger D.A., White F.M.;
Proc. Natl. Acad. Sci. U.S.A. 104:5860-5865(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-991; TYR-998; SER-1166;TYR-1069; TYR-1172 AND TYR-1197, AND MASS SPECTROMETRY.
PubMed: 17389395

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-693; SER-991; SER-995;TYR-998; SER-1064; TYR-1069; TYR-1092; TYR-1110; TYR-1138; TYR-1172AND TYR-1197, AND MASS SPECTROMETRY.
PubMed: 17081983

"Time-resolved mass spectrometry of tyrosine phosphorylation sites inthe epidermal growth factor receptor signaling network reveals dynamicmodules.";
Zhang Y., Wolf-Yadlin A., Ross P.L., Pappin D.J., Rush J.,Lauffenburger D.A., White F.M.;
Mol. Cell. Proteomics 4:1240-1250(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-998; TYR-1069; TYR-1092;SER-1166 AND TYR-1172, AND MASS SPECTROMETRY.
PubMed: 15951569

"Extended Range Proteomic Analysis (ERPA): a new and sensitive LC-MSplatform for high sequence coverage of complex proteins with extensivepost-translational modifications-comprehensive analysis of beta-caseinand epidermal growth factor receptor (EGFR).";
Wu S.L., Kim J., Hancock W.S., Karger B.;
J. Proteome Res. 4:1155-1170(2005).
Cited for: GLYCOSYLATION AT ASN-56; ASN-128; ASN-175; ASN-196; ASN-352; ASN-361;ASN-413; ASN-444; ASN-528; ASN-568 AND ASN-603, PHOSPHORYLATION ATTHR-693; SER-991 AND SER-1026, AND MASS SPECTROMETRY.
PubMed: 16083266

"Epidermal growth factor receptor threonine and serine residuesphosphorylated in vivo.";
Heisermann G.J., Gill G.N.;
J. Biol. Chem. 263:13152-13158(1988).
Cited for: PROTEIN SEQUENCE OF 687-705; 986-998; 1000-1023; 1026-1030 AND1068-1077, AND PHOSPHORYLATION AT THR-693; SER-695; SER-1070 ANDSER-1071.
PubMed: 3138233

"Large-scale proteomics analysis of the human kinome.";
Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.;
Mol. Cell. Proteomics 8:1751-1764(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-693, AND MASSSPECTROMETRY.
PubMed: 19369195

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-693, AND MASSSPECTROMETRY.
PubMed: 19413330

"Proteomics analysis of protein kinases by target class-selectiveprefractionation and tandem mass spectrometry.";
Wissing J., Jaensch L., Nimtz M., Dieterich G., Hornberger R.,Keri G., Wehland J., Daub H.;
Mol. Cell. Proteomics 6:537-547(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-693, AND MASSSPECTROMETRY.
PubMed: 17192257

"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-693, AND MASSSPECTROMETRY.
PubMed: 15302935

"Cell-type specific phosphorylation of threonines T654 and T669 by PKDdefines the signal capacity of the EGF receptor.";
Bagowski C.P., Stein-Gerlach M., Choidas A., Ullrich A.;
EMBO J. 18:5567-5576(1999).
Cited for: PHOSPHORYLATION AT THR-678 AND THR-693.
PubMed: 10523301

"Mechanism for activation of the EGF receptor catalytic domain by thejuxtamembrane segment.";
Jura N., Endres N.F., Engel K., Deindl S., Das R., Lamers M.H.,Wemmer D.E., Zhang X., Kuriyan J.;
Cell 137:1293-1307(2009).
Cited for: X-RAY CRYSTALLOGRAPHY (2.96 ANGSTROMS) OF 696-1022, CATALYTICACTIVITY, PHOSPHORYLATION AT TYR-998; TYR-1016 AND TYR-1197,MUTAGENESIS OF LEU-688; GLU-690; LEU-692; ARG-977 AND1005-GLU-ASP-1006, AND SUBUNIT.
PubMed: 19563760

"An extensive survey of tyrosine phosphorylation revealing new sitesin human mammary epithelial cells.";
Heibeck T.H., Ding S.-J., Opresko L.K., Zhao R., Schepmoes A.A.,Yang F., Tolmachev A.V., Monroe M.E., Camp D.G. II, Smith R.D.,Wiley H.S., Qian W.-J.;
J. Proteome Res. 8:3852-3861(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-998; TYR-1016; TYR-1092;TYR-1110; TYR-1138; TYR-1172 AND TYR-1197, AND MASS SPECTROMETRY.
PubMed: 19534553

"Global survey of phosphotyrosine signaling identifies oncogenickinases in lung cancer.";
Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J.,Lee K., Reeves C., Li Y., Hu Y., Tan Z., Stokes M., Sullivan L.,Mitchell J., Wetzel R., Macneill J., Ren J.M., Yuan J.,Bakalarski C.E., Villen J., Kornhauser J.M., Smith B., Li D., Zhou X.,Gygi S.P., Gu T.-L., Polakiewicz R.D., Rush J., Comb M.J.;
Cell 131:1190-1203(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-869; TYR-1092; TYR-1172AND TYR-1197, AND MASS SPECTROMETRY.
PubMed: 18083107

"Global phosphoproteome analysis on human HepG2 hepatocytes usingreversed-phase diagonal LC.";
Gevaert K., Staes A., Van Damme J., De Groot S., Hugelier K.,Demol H., Martens L., Goethals M., Vandekerckhove J.;
Proteomics 5:3589-3599(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-978, AND MASSSPECTROMETRY.
PubMed: 16097034

"Identification and characterization of signal transducer andactivator of transcription 3 recruitment sites within the epidermalgrowth factor receptor.";
Shao H., Cheng H.Y., Cook R.G., Tweardy D.J.;
Cancer Res. 63:3923-3930(2003).
Cited for: FUNCTION IN CELL PROLIFERATION, INTERACTION WITH STAT3, ANDPHOSPHORYLATION AT TYR-1092 AND TYR-1110.
PubMed: 12873986

"All autophosphorylation sites of epidermal growth factor (EGF)receptor and HER2/neu are located in their carboxyl-terminal tails.Identification of a novel site in EGF receptor.";
Margolis B.L., Lax I., Kris R., Dombalagian M., Honegger A.M.,Howk R., Givol D., Ullrich A., Schlessinger J.;
J. Biol. Chem. 264:10667-10671(1989).
Cited for: AUTOPHOSPHORYLATION AT TYR-1110.
PubMed: 2543678

Ubiquitylation

"Differential regulation of EGF receptor internalization anddegradation by multiubiquitination within the kinase domain.";
Huang F., Kirkpatrick D., Jiang X., Gygi S.P., Sorkin A.;
Mol. Cell 21:737-748(2006).
Cited for: PROTEIN SEQUENCE OF 861-875 AND 914-932, UBIQUITINATION AT LYS-716;LYS-737; LYS-754; LYS-867; LYS-929 AND LYS-970, AND MASS SPECTROMETRY.
PubMed: 16543144