XRRA1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: XRRA1_HUMAN
• UniProt AC: Q6P2D8
• Protein Name: X-ray radiation resistance-associated protein 1
• Gene Name: XRRA1 {ECO:0000312|EMBL:AAH64584.1}
• Organism: Homo sapiens (Human).
• Sequence Length: 792
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Description: May be involved in the response of cells to X-ray radiation..
• Protein Sequence: MAFSGIYKLDDGKPYLNNCFPARNLLRVPEEGQGHWLVVQKGNLKKKPKGLVGAQAERRESLKATSFEFKGKKESRRENQVDLPGHILDQAFLLKHHCVRKPSDLCTINAKENDFKHFHSVIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESVDWNGGRGSPHKEPQFMLQSKPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKSLKARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFPSLCEFVFHNNPLVAHTRGVPPLLKSFLQERLGIHLIRRKIVKPKHHVLMSRKESWKVKSEIPKVPKQPLVLHHPRMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDTTVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVKGTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKLDTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRLVNHKQYLEAKRLLKEFQARYRQLVSGSLRTVFGTTPLPMACPALSESQPKFGHFLEFMDEFCQEPTASDSQG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
61	Phosphorylation	AQAERRESLKATSFE HHHHHHHHHHCCCEE	33.10	30622161
70	Acetylation	KATSFEFKGKKESRR HCCCEEECCCHHHHC	63.72	19807285
195	Phosphorylation	HLRVLLLTGNGLTSL CCEEEECCCCCCCCC	28.68	25693802
200	Phosphorylation	LLTGNGLTSLPPNLA ECCCCCCCCCCCCCC	29.61	25693802
201	Phosphorylation	LTGNGLTSLPPNLAV CCCCCCCCCCCCCCH	43.87	25693802
214	Phosphorylation	AVAEQEASVTSLTSK CHHHEECCHHHHCCC	25.77	25693802
216	Phosphorylation	AEQEASVTSLTSKRY HHEECCHHHHCCCCE	18.61	25693802
217	Phosphorylation	EQEASVTSLTSKRYI HEECCHHHHCCCCEE	27.74	25693802
219	Phosphorylation	EASVTSLTSKRYILR ECCHHHHCCCCEEEE	31.78	25693802
220	Phosphorylation	ASVTSLTSKRYILRF CCHHHHCCCCEEEEC	22.04	25693802
314	Phosphorylation	DSDEQLDYTVLPMKK CCHHHCCCEEEEECC	13.82	27642862
358	Phosphorylation	FEILPVKSLKARNQT EEEEECCCHHHCCCC	35.02	24719451
375	Phosphorylation	PPFPELRYLSLAYNK CCCHHHHHHHHHHHH	17.17	18452278
377	Phosphorylation	FPELRYLSLAYNKIA CHHHHHHHHHHHHHC	11.30	29083192
380	Phosphorylation	LRYLSLAYNKIAKED HHHHHHHHHHHCCCC	23.45	29083192
477	Phosphorylation	PRMTTTKSPSKDMLE CCCCCCCCCCCCCCC	32.11	25693802
479	Phosphorylation	MTTTKSPSKDMLEPE CCCCCCCCCCCCCCH	48.67	25693802
498	Phosphorylation	EDLPTTKSTSVESEM HCCCCCCCCCCCCCC	24.67	-
499	Phosphorylation	DLPTTKSTSVESEMP CCCCCCCCCCCCCCC	38.04	22210691
507	Phosphorylation	SVESEMPTENLEGHS CCCCCCCCCCCCCCC	35.87	25693802
514	Phosphorylation	TENLEGHSPSCRTFV CCCCCCCCCCCCCCC	29.39	25693802
516	Phosphorylation	NLEGHSPSCRTFVPL CCCCCCCCCCCCCCC	21.17	25693802
549	Phosphorylation	SDTTVRLSPERPSDE CCCEEECCCCCCCCC	17.72	24719451
613	Phosphorylation	LPTAFLPSKYHGYEE CCCCCCCCCCCCHHH	48.25	24719451
754	Phosphorylation	SLRTVFGTTPLPMAC CCHHHHCCCCCCCCC	17.49	22210691
755	Phosphorylation	LRTVFGTTPLPMACP CHHHHCCCCCCCCCH	24.17	22210691
765	Phosphorylation	PMACPALSESQPKFG CCCCHHHCCCCCCCH	36.99	28674151
767	Phosphorylation	ACPALSESQPKFGHF CCHHHCCCCCCCHHH	48.70	28674151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of XRRA1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of XRRA1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of XRRA1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of XRRA1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.