ZN114_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN114_HUMAN
• UniProt AC: Q8NC26
• Protein Name: Zinc finger protein 114
• Gene Name: ZNF114
• Organism: Homo sapiens (Human).
• Sequence Length: 417
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MSQDSVTFADVAVNFTKEEWTLLDPAQRNLYRDVMLENSRNLAFIDWATPCKTKDATPQPDILPKRTFPEANRVCLTSISSQHSTLREDWRCPKTEEPHRQGVNNVKPPAVAPEKDESPVSICEDHEMRNHSKPTCRLVPSQGDSIRQCILTRDSSIFKYNPVLNDSQKTHENNEDDGVLGWNIQWVPCGRKTELKSSTWTGSQNTVHHIRDEIDTGANRHQRNPFGKAFREDGSLRAHNTHGREKMYDFTQCENTSRNNSIHAMQMQLYTAETNKKDCQTGATSANAPNSGSHKSHCTGEKTHKCPECGRAFFYQSFLMRHMKIHTGEKPYECGKCGKAFRYSLHLNKHLRKHVVQKKPYECEECGKVIRESSKYTHIRSHTGEKPYKCKTCGKDFAKSSGLKKHLKTHKDEKPCE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSQDSVTFA ------CCCCCEEEE	42.57	20873877
5	Phosphorylation	---MSQDSVTFADVA ---CCCCCEEEEEEE	18.54	20873877
7	Phosphorylation	-MSQDSVTFADVAVN -CCCCCEEEEEEEEC	19.63	20873877
67	O-linked_Glycosylation	PDILPKRTFPEANRV CCCCCCCCCCCCCCE	50.06	30379171
77	Phosphorylation	EANRVCLTSISSQHS CCCCEEEEECCCCCC	20.91	28555341
78	Phosphorylation	ANRVCLTSISSQHST CCCEEEEECCCCCCC	13.92	28555341
118	Phosphorylation	VAPEKDESPVSICED CCCCCCCCCCCCCCC	40.51	25159151
121	Phosphorylation	EKDESPVSICEDHEM CCCCCCCCCCCCHHH	25.55	29449344
132	Phosphorylation	DHEMRNHSKPTCRLV CHHHCCCCCCCEEEC	43.83	29449344
135	Phosphorylation	MRNHSKPTCRLVPSQ HCCCCCCCEEECCCC	17.62	-
152	Phosphorylation	SIRQCILTRDSSIFK CHHHHEEECCCHHHH	16.72	28555341
156	Phosphorylation	CILTRDSSIFKYNPV HEEECCCHHHHCCCC	36.01	24719451
167	Phosphorylation	YNPVLNDSQKTHENN CCCCCCCCHHCCCCC	32.29	25159151
235	Phosphorylation	KAFREDGSLRAHNTH HHHCCCCCCCCCCCC	27.31	25159151
248	Phosphorylation	THGREKMYDFTQCEN CCCCCCCCCCCCCCC	20.97	-
270	Phosphorylation	HAMQMQLYTAETNKK EEEEEEEEECCCCCH	6.24	-
291	Phosphorylation	TSANAPNSGSHKSHC CCCCCCCCCCCCCCC	40.38	25627689
383	Phosphorylation	YTHIRSHTGEKPYKC CCCCCCCCCCCCEEC	48.56	24719451
400	Phosphorylation	CGKDFAKSSGLKKHL CCHHHHHHHHHHHHH	26.64	28102081
401	Phosphorylation	GKDFAKSSGLKKHLK CHHHHHHHHHHHHHH	47.65	28102081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN114_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN114_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN114_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZN114_HUMAN	ZNF114	physical	25416956
TIF1B_HUMAN	TRIM28	physical	26186194
2AAB_HUMAN	PPP2R1B	physical	26186194
2AAA_HUMAN	PPP2R1A	physical	26186194
CBX5_HUMAN	CBX5	physical	26186194
2ABG_HUMAN	PPP2R2C	physical	26186194
PP2AA_HUMAN	PPP2CA	physical	26186194
CUED1_HUMAN	CUEDC1	physical	26186194
CUED1_HUMAN	CUEDC1	physical	28514442
2ABG_HUMAN	PPP2R2C	physical	28514442
PP2AA_HUMAN	PPP2CA	physical	28514442
2AAB_HUMAN	PPP2R1B	physical	28514442
TIF1B_HUMAN	TRIM28	physical	28514442
2AAA_HUMAN	PPP2R1A	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.