MPV17_HUMAN - dbPTM
MPV17_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MPV17_HUMAN
UniProt AC P39210
Protein Name Protein Mpv17
Gene Name MPV17
Organism Homo sapiens (Human).
Sequence Length 176
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein .
Protein Description Involved in mitochondria homeostasis. May be involved in the metabolism of reactive oxygen species and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance..
Protein Sequence MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCGFVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNWAKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
22PhosphorylationPWKVQVLTAGSLMGL
CCEEEEEEHHHHCCH
30.0724043423
25PhosphorylationVQVLTAGSLMGLGDI
EEEEEHHHHCCHHHH
16.8424043423
34PhosphorylationMGLGDIISQQLVERR
CCHHHHHHHHHHHHC
16.5324043423
80PhosphorylationLDRFIPGTTKVDALK
HHHHCCCCCHHHHHH
20.35-
82UbiquitinationRFIPGTTKVDALKKM
HHCCCCCHHHHHHHH
37.65-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MPV17_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MPV17_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MPV17_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RM23_HUMANMRPL23physical
22939629
RM11_HUMANMRPL11physical
22939629
RM32_HUMANMRPL32physical
22939629
NDUB9_HUMANNDUFB9physical
22939629
RM17_HUMANMRPL17physical
22939629
RHOA_HUMANRHOAphysical
22939629
NDUB7_HUMANNDUFB7physical
22939629
PUF60_HUMANPUF60physical
22939629
VDAC2_HUMANVDAC2physical
22939629
NB5R1_HUMANCYB5R1physical
22939629
RALA_HUMANRALAphysical
22939629
SFXN3_HUMANSFXN3physical
22939629
RM40_HUMANMRPL40physical
22939629
NDUB4_HUMANNDUFB4physical
22939629
RM22_HUMANMRPL22physical
22939629
RM13_HUMANMRPL13physical
22939629
NDUAC_HUMANNDUFA12physical
22939629
VATD_HUMANATP6V1Dphysical
22939629
NDUAA_HUMANNDUFA10physical
22939629
RM38_HUMANMRPL38physical
22939629
NDUS7_HUMANNDUFS7physical
22939629
RS15_HUMANRPS15physical
22939629
RAI3_HUMANGPRC5Aphysical
22939629
SCFD1_HUMANSCFD1physical
22939629
PTCD3_HUMANPTCD3physical
22939629
NDUS8_HUMANNDUFS8physical
22939629
NDUB6_HUMANNDUFB6physical
22939629
VATF_HUMANATP6V1Fphysical
22939629
UCRI_HUMANUQCRFS1physical
22939629
RT14_HUMANMRPS14physical
22939629
RM44_HUMANMRPL44physical
22939629
QCR6_HUMANUQCRHphysical
22939629
NDUB5_HUMANNDUFB5physical
22939629
NDUS6_HUMANNDUFS6physical
22939629
RT16_HUMANMRPS16physical
22939629
RM51_HUMANMRPL51physical
22939629
SCMC1_HUMANSLC25A24physical
22939629
MSLN_HUMANMSLNphysical
22939629

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MPV17_HUMAN

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Related Literatures of Post-Translational Modification

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