| UniProt ID | RM44_HUMAN | |
|---|---|---|
| UniProt AC | Q9H9J2 | |
| Protein Name | 39S ribosomal protein L44, mitochondrial | |
| Gene Name | MRPL44 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 332 | |
| Subcellular Localization | Mitochondrion . | |
| Protein Description | Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome.. | |
| Protein Sequence | MASGLVRLLQQGHRCLLAPVAPKLVPPVRGVKKGFRAAFRFQKELERQRLLRCPPPPVRRSEKPNWDYHAEIQAFGHRLQENFSLDLLKTAFVNSCYIKSEEAKRQQLGIEKEAVLLNLKSNQELSEQGTSFSQTCLTQFLEDEYPDMPTEGIKNLVDFLTGEEVVCHVARNLAVEQLTLSEEFPVPPAVLQQTFFAVIGALLQSSGPERTALFIRDFLITQMTGKELFEMWKIINPMGLLVEELKKRNVSAPESRLTRQSGGTTALPLYFVGLYCDKKLIAEGPGETVLVAEEEAARVALRKLYGFTENRRPWNYSKPKETLRAEKSITAS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MASGLVRLLQ -----CCCHHHHHHH | 31.21 | 21406692 | |
| 43 | Acetylation | RAAFRFQKELERQRL HHHHHHHHHHHHHHH | 62.65 | 27452117 | |
| 84 | Phosphorylation | HRLQENFSLDLLKTA HHHHHHCCHHHHHHH | 32.33 | - | |
| 90 | Phosphorylation | FSLDLLKTAFVNSCY CCHHHHHHHHHHHEE | 25.87 | 21406692 | |
| 95 | Phosphorylation | LKTAFVNSCYIKSEE HHHHHHHHEEECCHH | 11.73 | 21406692 | |
| 97 | Phosphorylation | TAFVNSCYIKSEEAK HHHHHHEEECCHHHH | 15.94 | 28152594 | |
| 99 | Acetylation | FVNSCYIKSEEAKRQ HHHHEEECCHHHHHH | 25.91 | 26051181 | |
| 100 | Phosphorylation | VNSCYIKSEEAKRQQ HHHEEECCHHHHHHH | 30.98 | - | |
| 112 | 2-Hydroxyisobutyrylation | RQQLGIEKEAVLLNL HHHCCCHHHHHHHHH | 49.40 | - | |
| 145 | Phosphorylation | TQFLEDEYPDMPTEG HHHHHHCCCCCCCHH | 19.49 | - | |
| 150 | Phosphorylation | DEYPDMPTEGIKNLV HCCCCCCCHHHHHHH | 39.96 | - | |
| 246 | Ubiquitination | GLLVEELKKRNVSAP HHHHHHHHHCCCCCC | 53.63 | 21906983 | |
| 247 | Ubiquitination | LLVEELKKRNVSAPE HHHHHHHHCCCCCCH | 62.93 | - | |
| 251 | Phosphorylation | ELKKRNVSAPESRLT HHHHCCCCCCHHHHC | 41.47 | 29978859 | |
| 255 | Phosphorylation | RNVSAPESRLTRQSG CCCCCCHHHHCCCCC | 31.37 | 29978859 | |
| 278 | Ubiquitination | FVGLYCDKKLIAEGP EEEEEECCEEEECCC | 46.01 | - | |
| 278 | Acetylation | FVGLYCDKKLIAEGP EEEEEECCEEEECCC | 46.01 | 30590467 | |
| 278 | Succinylation | FVGLYCDKKLIAEGP EEEEEECCEEEECCC | 46.01 | 23954790 | |
| 279 | Ubiquitination | VGLYCDKKLIAEGPG EEEEECCEEEECCCC | 31.69 | - | |
| 288 | Phosphorylation | IAEGPGETVLVAEEE EECCCCCEEEEEHHH | 25.67 | - | |
| 303 | Ubiquitination | AARVALRKLYGFTEN HHHHHHHHHHCCCCC | 47.08 | - | |
| 303 | 2-Hydroxyisobutyrylation | AARVALRKLYGFTEN HHHHHHHHHHCCCCC | 47.08 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RM44_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RM44_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RM44_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MIC60_HUMAN | IMMT | physical | 16169070 | |
| SETB1_HUMAN | SETDB1 | physical | 16169070 | |
| VIME_HUMAN | VIM | physical | 16169070 | |
| MIC60_HUMAN | IMMT | physical | 21900206 | |
| SHC1_HUMAN | SHC1 | physical | 21900206 | |
| CEP70_HUMAN | CEP70 | physical | 21900206 | |
| TIP_HUMAN | ITFG1 | physical | 21900206 | |
| SEM5B_HUMAN | SEMA5B | physical | 21900206 | |
| VIME_HUMAN | VIM | physical | 21900206 | |
| UBP22_HUMAN | USP22 | physical | 21900206 | |
| PTN_HUMAN | PTN | physical | 21900206 | |
| NGEF_HUMAN | NGEF | physical | 21900206 | |
| SETB1_HUMAN | SETDB1 | physical | 21900206 | |
| ZN235_HUMAN | ZNF235 | physical | 21900206 | |
| RM51_HUMAN | MRPL51 | physical | 22939629 | |
| RM47_HUMAN | MRPL47 | physical | 22939629 | |
| RM50_HUMAN | MRPL50 | physical | 22939629 | |
| TM177_HUMAN | TMEM177 | physical | 22939629 | |
| TSR1_HUMAN | TSR1 | physical | 22939629 | |
| VPP1_HUMAN | ATP6V0A1 | physical | 22939629 | |
| SPCS2_HUMAN | SPCS2 | physical | 22939629 | |
| SYJ2B_HUMAN | SYNJ2BP | physical | 22939629 | |
| PLPP2_HUMAN | PPAP2C | physical | 21988832 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| 615395 | Combined oxidative phosphorylation deficiency 16 (COXPD16) | |||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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