RM38_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RM38_HUMAN
• UniProt AC: Q96DV4
• Protein Name: 39S ribosomal protein L38, mitochondrial
• Gene Name: MRPL38
• Organism: Homo sapiens (Human).
• Sequence Length: 380
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MAAPWWRAALCECRRWRGFSTSAVLGRRTPPLGPMPNSDIDLSNLERLEKYRSFDRYRRRAEQEAQAPHWWRTYREYFGEKTDPKEKIDIGLPPPKVSRTQQLLERKQAIQELRANVEEERAARLRTASVPLDAVRAEWERTCGPYHKQRLAEYYGLYRDLFHGATFVPRVPLHVAYAVGEDDLMPVYCGNEVTPTEAAQAPEVTYEAEEGSLWTLLLTSLDGHLLEPDAEYLHWLLTNIPGNRVAEGQVTCPYLPPFPARGSGIHRLAFLLFKQDQPIDFSEDARPSPCYQLAQRTFRTFDFYKKHQETMTPAGLSFFQCRWDDSVTYIFHQLLDMREPVFEFVRPPPYHPKQKRFPHRQPLRYLDRYRDSHEPTYGIY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	RRWRGFSTSAVLGRR HCCCCCCHHHHCCCC	20.60	27251275
22	Phosphorylation	RWRGFSTSAVLGRRT CCCCCCHHHHCCCCC	18.38	27251275
29	Phosphorylation	SAVLGRRTPPLGPMP HHHCCCCCCCCCCCC	28.09	27251275
38	Phosphorylation	PLGPMPNSDIDLSNL CCCCCCCCCCCHHHH	30.03	23532336
43	Phosphorylation	PNSDIDLSNLERLEK CCCCCCHHHHHHHHH	35.30	23532336
62	Ubiquitination	DRYRRRAEQEAQAPH HHHHHHHHHHHCCCH	47.33	21890473
73	Ubiquitination	QAPHWWRTYREYFGE CCCHHHHHHHHHHCC	17.14	21890473
81	Ubiquitination	YREYFGEKTDPKEKI HHHHHCCCCCCHHHC	59.62	27667366
81	Acetylation	YREYFGEKTDPKEKI HHHHHCCCCCCHHHC	59.62	7824209
85	Acetylation	FGEKTDPKEKIDIGL HCCCCCCHHHCCCCC	74.56	7824219
96	Ubiquitination	DIGLPPPKVSRTQQL CCCCCCCCCCHHHHH	59.63	21890473
107	Ubiquitination	TQQLLERKQAIQELR HHHHHHHHHHHHHHH	34.40	21890473
148	Ubiquitination	RTCGPYHKQRLAEYY HHHCHHHHHHHHHHH	31.13	27667366
154	Phosphorylation	HKQRLAEYYGLYRDL HHHHHHHHHHHHHHH	9.38	28152594
155	Phosphorylation	KQRLAEYYGLYRDLF HHHHHHHHHHHHHHH	7.67	28152594
158	Phosphorylation	LAEYYGLYRDLFHGA HHHHHHHHHHHHCCC	9.56	28152594
169	Ubiquitination	FHGATFVPRVPLHVA HCCCCCCCCCCEEEE	27.62	-
282	Phosphorylation	QDQPIDFSEDARPSP CCCCCCCCCCCCCCH	30.71	28152594
288	Phosphorylation	FSEDARPSPCYQLAQ CCCCCCCCHHHHHHH	23.27	28152594
291	Phosphorylation	DARPSPCYQLAQRTF CCCCCHHHHHHHHHH	15.22	28152594
305	2-Hydroxyisobutyrylation	FRTFDFYKKHQETMT HHHHHHHHHHHHHCC	43.71	-
319	Ubiquitination	TPAGLSFFQCRWDDS CCCCCEEEEECCCHH	6.35	21890473
350	Phosphorylation	EFVRPPPYHPKQKRF HHCCCCCCCCCCCCC	36.21	20068231
353	Ubiquitination	RPPPYHPKQKRFPHR CCCCCCCCCCCCCCC	55.96	21890473
377	Phosphorylation	RDSHEPTYGIY---- CCCCCCCCCCC----	16.55	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RM38_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RM38_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RM38_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ERG28_HUMAN	C14orf1	physical	16169070
RM44_HUMAN	MRPL44	physical	22939629
RM39_HUMAN	MRPL39	physical	22939629
RM50_HUMAN	MRPL50	physical	22939629
RM40_HUMAN	MRPL40	physical	22939629
RT09_HUMAN	MRPS9	physical	22939629
RM49_HUMAN	MRPL49	physical	22939629
RM51_HUMAN	MRPL51	physical	22939629
RM52_HUMAN	MRPL52	physical	22939629
TSR1_HUMAN	TSR1	physical	22939629
RT63_HUMAN	MRPL57	physical	22939629
TM177_HUMAN	TMEM177	physical	22939629
ANM6_HUMAN	PRMT6	physical	23455924
DOCK8_HUMAN	DOCK8	physical	25416956
PR40A_HUMAN	PRPF40A	physical	26344197
KDM3B_HUMAN	KDM3B	physical	28514442
SYFM_HUMAN	FARS2	physical	28514442
FA26D_HUMAN	FAM26D	physical	28514442
HPHL1_HUMAN	HEPHL1	physical	28514442
DSG4_HUMAN	DSG4	physical	28514442
SPTB1_HUMAN	SPTB	physical	28514442
S10A3_HUMAN	S100A3	physical	28514442
CRBG1_HUMAN	AIM1	physical	28514442
NDUF5_HUMAN	NDUFAF5	physical	28514442
PADI3_HUMAN	PADI3	physical	28514442
S10A7_HUMAN	S100A7	physical	28514442
KPRP_HUMAN	KPRP	physical	28514442
LRC15_HUMAN	LRRC15	physical	28514442
M1IP1_HUMAN	MID1IP1	physical	28514442
SPB4_HUMAN	SERPINB4	physical	28514442
LYG2_HUMAN	LYG2	physical	28514442
NEUR2_HUMAN	NEU2	physical	28514442
RM41_HUMAN	MRPL41	physical	28514442
RNAS7_HUMAN	RNASE7	physical	28514442
ARMC8_HUMAN	ARMC8	physical	28514442
LPP_HUMAN	LPP	physical	28514442
TCPW_HUMAN	CCT6B	physical	28514442
DUS14_HUMAN	DUSP14	physical	28514442
ANGE2_HUMAN	ANGEL2	physical	28514442
RM18_HUMAN	MRPL18	physical	28514442
MAEA_HUMAN	MAEA	physical	28514442
SPB3_HUMAN	SERPINB3	physical	28514442
RBP10_HUMAN	RANBP10	physical	28514442
MTMR4_HUMAN	MTMR4	physical	28514442
ARF6_HUMAN	ARF6	physical	28514442
RM37_HUMAN	MRPL37	physical	28514442
ANM6_HUMAN	PRMT6	physical	28514442
CUED1_HUMAN	CUEDC1	physical	28514442
FBX50_HUMAN	NCCRP1	physical	28514442
FUCO_HUMAN	FUCA1	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.