RM37_HUMAN - dbPTM
RM37_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RM37_HUMAN
UniProt AC Q9BZE1
Protein Name 39S ribosomal protein L37, mitochondrial
Gene Name MRPL37
Organism Homo sapiens (Human).
Sequence Length 423
Subcellular Localization Mitochondrion .
Protein Description
Protein Sequence MALASGPARRALAGSGQLGLGGFGAPRRGAYEWGVRSTRKSEPPPLDRVYEIPGLEPITFAGKMHFVPWLARPIFPPWDRGYKDPRFYRSPPLHEHPLYKDQACYIFHHRCRLLEGVKQALWLTKTKLIEGLPEKVLSLVDDPRNHIENQDECVLNVISHARLWQTTEEIPKRETYCPVIVDNLIQLCKSQILKHPSLARRICVQNSTFSATWNRESLLLQVRGSGGARLSTKDPLPTIASREEIEATKNHVLETFYPISPIIDLHECNIYDVKNDTGFQEGYPYPYPHTLYLLDKANLRPHRLQPDQLRAKMILFAFGSALAQARLLYGNDAKVLEQPVVVQSVGTDGRVFHFLVFQLNTTDLDCNEGVKNLAWVDSDQLLYQHFWCLPVIKKRVVVEPVGPVGFKPETFRKFLALYLHGAA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
27MethylationLGGFGAPRRGAYEWG
CCCCCCCCCCCCCCC		49.48-
48MethylationSEPPPLDRVYEIPGL
CCCCCCCCEEECCCC		40.37115483767
127AcetylationALWLTKTKLIEGLPE
HHHHHHHHHCCCCCH		49.3619608861
127UbiquitinationALWLTKTKLIEGLPE
HHHHHHHHHCCCCCH		49.3619608861
1272-HydroxyisobutyrylationALWLTKTKLIEGLPE
HHHHHHHHHCCCCCH		49.36-
135UbiquitinationLIEGLPEKVLSLVDD
HCCCCCHHHHHHHCC		46.6821890473
153GlutathionylationHIENQDECVLNVISH
CCCCCCHHHHHHHHH		5.9222555962
172UbiquitinationQTTEEIPKRETYCPV
HCCCCCCCCCCCHHH		69.4021890473
189UbiquitinationDNLIQLCKSQILKHP
HHHHHHHHHHHHHCH		54.72-
233UbiquitinationGGARLSTKDPLPTIA
CCCCCCCCCCCCCCC		54.7121906983
238PhosphorylationSTKDPLPTIASREEI
CCCCCCCCCCCHHHH		36.5420068231
249UbiquitinationREEIEATKNHVLETF
HHHHHHHHCHHHCCC		52.70-
320PhosphorylationMILFAFGSALAQARL
HHHHHHHHHHHHHHH		17.4129507054
334UbiquitinationLLYGNDAKVLEQPVV
HHHCCCCCHHCCCEE		50.6621890473
407UbiquitinationPVGPVGFKPETFRKF
CCCCCCCCHHHHHHH		35.702190698
407AcetylationPVGPVGFKPETFRKF
CCCCCCCCHHHHHHH		35.7026822725
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RM37_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RM37_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RM37_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RM39_HUMANMRPL39physical
22939629
RM38_HUMANMRPL38physical
22939629
RM44_HUMANMRPL44physical
22939629
RM41_HUMANMRPL41physical
22939629
RM50_HUMANMRPL50physical
22939629
RM51_HUMANMRPL51physical
22939629
RM40_HUMANMRPL40physical
22939629
RM42_HUMANMRPL42physical
22939629
TSR1_HUMANTSR1physical
22939629
CH60_HUMANHSPD1physical
26186194
RM46_HUMANMRPL46physical
26186194
RM09_HUMANMRPL9physical
26186194
RM11_HUMANMRPL11physical
26186194
RM40_HUMANMRPL40physical
26186194
RM03_HUMANMRPL3physical
26186194
PDPR_HUMANPDPRphysical
26186194
RM24_HUMANMRPL24physical
26186194
RM49_HUMANMRPL49physical
26186194
PDP1_HUMANPDP1physical
26186194
RM27_HUMANMRPL27physical
26186194
RM55_HUMANMRPL55physical
26186194
MASU1_HUMANMALSU1physical
26186194
RM47_HUMANMRPL47physical
26186194
RM16_HUMANMRPL16physical
26186194
ACOT2_HUMANACOT2physical
26186194
RM38_HUMANMRPL38physical
26186194
ICT1_HUMANICT1physical
26186194
RM02_HUMANMRPL2physical
26186194
RM13_HUMANMRPL13physical
26186194
P20D2_HUMANPM20D2physical
26186194
G45IP_HUMANGADD45GIP1physical
26186194
RM15_HUMANMRPL15physical
26186194
RT30_HUMANMRPS30physical
26186194
RM30_HUMANMRPL30physical
26186194
DHRS4_HUMANDHRS4physical
26186194
RM14_HUMANMRPL14physical
26186194
RM42_HUMANMRPL42physical
26186194
ADAS_HUMANAGPSphysical
26344197
ATP5L_HUMANATP5Lphysical
26344197
ICT1_HUMANICT1physical
26344197
RM13_HUMANMRPL13physical
26344197
RM17_HUMANMRPL17physical
26344197
RM24_HUMANMRPL24physical
26344197
RM47_HUMANMRPL47physical
26344197
RM09_HUMANMRPL9physical
26344197
PDCD6_HUMANPDCD6physical
26344197
STML2_HUMANSTOML2physical
26344197
QCR2_HUMANUQCRC2physical
26344197
PDP1_HUMANPDP1physical
28514442
RT30_HUMANMRPS30physical
28514442
RM47_HUMANMRPL47physical
28514442
CH60_HUMANHSPD1physical
28514442
MASU1_HUMANMALSU1physical
28514442
RM13_HUMANMRPL13physical
28514442
DHRS4_HUMANDHRS4physical
28514442
DNLZ_HUMANDNLZphysical
28514442
RM55_HUMANMRPL55physical
28514442
RM40_HUMANMRPL40physical
28514442
RM49_HUMANMRPL49physical
28514442
RM46_HUMANMRPL46physical
28514442
RM27_HUMANMRPL27physical
28514442
RM11_HUMANMRPL11physical
28514442
RM24_HUMANMRPL24physical
28514442
RM51_HUMANMRPL51physical
28514442
RM16_HUMANMRPL16physical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RM37_HUMAN

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Related Literatures of Post-Translational Modification
Acetylation
ReferencePubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;
Science 325:834-840(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-127, AND MASS SPECTROMETRY.

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