RM16_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RM16_HUMAN
• UniProt AC: Q9NX20
• Protein Name: 39S ribosomal protein L16, mitochondrial
• Gene Name: MRPL16
• Organism: Homo sapiens (Human).
• Sequence Length: 251
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MWRLLARASAPLLRVPLSDSWALLPASAGVKTLLPVPSFEDVSIPEKPKLRFIERAPLVPKVRREPKNLSDIRGPSTEATEFTEGNFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFAIWRVPAPFKPITRKSVGHRMGGGKGAIDHYVTPVKAGRLVVEMGGRCEFEEVQGFLDQVAHKLPFAAKAVSRGTLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGKYWGKFYMPKRV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	WRLLARASAPLLRVP HHHHHHHCCCEEECC	25.51	23403867
32	Phosphorylation	PASAGVKTLLPVPSF ECCCCCEEEEECCCC	30.99	30108239
38	Phosphorylation	KTLLPVPSFEDVSIP EEEEECCCCCCCCCC	41.31	30108239
43	Phosphorylation	VPSFEDVSIPEKPKL CCCCCCCCCCCCCCC	44.76	23186163
47	Acetylation	EDVSIPEKPKLRFIE CCCCCCCCCCCCEEE	41.94	23236377
47	Malonylation	EDVSIPEKPKLRFIE CCCCCCCCCCCCEEE	41.94	26320211
49	Ubiquitination	VSIPEKPKLRFIERA CCCCCCCCCCEEECC	64.46	-
61	Ubiquitination	ERAPLVPKVRREPKN ECCCCCCCCCCCCCC	40.68	24816145
70	Phosphorylation	RREPKNLSDIRGPST CCCCCCHHHCCCCCC	40.15	26091039
108	Phosphorylation	HFEMMRLTINRSMDP CHHHEEEEECCCCCC	13.07	27461979
112	Phosphorylation	MRLTINRSMDPKNMF EEEEECCCCCCCCCE	24.05	27461979
129	Ubiquitination	WRVPAPFKPITRKSV EECCCCCCCCCCCCC	34.16	27667366
150	Phosphorylation	GKGAIDHYVTPVKAG CCCCCCEEECCCCCC	11.41	-
155	Ubiquitination	DHYVTPVKAGRLVVE CEEECCCCCCCEEEE	46.45	-
155	2-Hydroxyisobutyrylation	DHYVTPVKAGRLVVE CEEECCCCCCCEEEE	46.45	-
188	Ubiquitination	HKLPFAAKAVSRGTL HHHHHHHHHHHHHHH	45.98	29967540
220	Phosphorylation	WTFERIATANMLGIR CHHHHHHHHHHHCCE	19.05	-
231	Phosphorylation	LGIRKVLSPYDLTHK HCCEECCCCCCCCCC	25.13	-
238	Ubiquitination	SPYDLTHKGKYWGKF CCCCCCCCCCCCCEE	52.44	-
249	Ubiquitination	WGKFYMPKRV----- CCEEECCCCC-----	49.62	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RM16_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RM16_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RM16_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RM40_HUMAN	MRPL40	physical	22939629
RM38_HUMAN	MRPL38	physical	22939629
RM22_HUMAN	MRPL22	physical	22939629
RM19_HUMAN	MRPL19	physical	22939629
TM177_HUMAN	TMEM177	physical	22939629
ROA1_HUMAN	HNRNPA1	physical	26186194
RT07_HUMAN	MRPS7	physical	26344197
SNX11_HUMAN	SNX11	physical	28514442
CH60_HUMAN	HSPD1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.