dbPTM

DNLZ_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DNLZ_HUMAN
UniProt AC	Q5SXM8
Protein Name	DNL-type zinc finger protein
Gene Name	DNLZ
Organism	Homo sapiens (Human).
Sequence Length	178
Subcellular Localization	Mitochondrion .
Protein Description	May function as a co-chaperone towards HSPA9/mortalin which, by itself, is prone to self-aggregation..
Protein Sequence	MLRTALRGAPRLLSRVQPRAPCLRRLWGRGARPEVAGRRRAWAWGWRRSSSEQGPGPAAALGRVEAAHYQLVYTCKVCGTRSSKRISKLAYHQGVVIVTCPGCQNHHIIADNLGWFSDLNGKRNIEEILTARGEQVHRVAGEGALELVLEAAGAPTSTAAPEAGEDEGPPSPGKTEPS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MLRTALRGAPR ----CHHHHHCCHHH	26.53	-
14	Phosphorylation	RGAPRLLSRVQPRAP CCHHHHHHHHCCCCH	34.69	-
49	Phosphorylation	WAWGWRRSSSEQGPG CHHHCCCCCCCCCCC	29.64	28348404
51	Phosphorylation	WGWRRSSSEQGPGPA HHCCCCCCCCCCCHH	34.87	-
156	Phosphorylation	LEAAGAPTSTAAPEA HHHCCCCCCCCCCCC	37.87	30108239
157	Phosphorylation	EAAGAPTSTAAPEAG HHCCCCCCCCCCCCC	18.26	30108239
158	Phosphorylation	AAGAPTSTAAPEAGE HCCCCCCCCCCCCCC	29.35	30108239
171	Phosphorylation	GEDEGPPSPGKTEPS CCCCCCCCCCCCCCC	49.79	30278072
175	Phosphorylation	GPPSPGKTEPS---- CCCCCCCCCCC----	60.07	29496963
178	Phosphorylation	SPGKTEPS------- CCCCCCCC-------	46.77	30108239

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DNLZ_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DNLZ_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DNLZ_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DNLZ_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DNLZ_HUMAN

Related Literatures of Post-Translational Modification