RM24_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RM24_HUMAN
• UniProt AC: Q96A35
• Protein Name: 39S ribosomal protein L24, mitochondrial
• Gene Name: MRPL24
• Organism: Homo sapiens (Human).
• Sequence Length: 216
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MRLSALLALASKVTLPPHYRYGMSPPGSVADKRKNPPWIRRRPVVVEPISDEDWYLFCGDTVEILEGKDAGKQGKVVQVIRQRNWVVVGGLNTHYRYIGKTMDYRGTMIPSEAPLLHRQVKLVDPMDRKPTEIEWRFTEAGERVRVSTRSGRIIPKPEFPRADGIVPETWIDGPKDTSVEDALERTYVPCLKTLQEEVMEAMGIKETRKYKKVYWY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	TLPPHYRYGMSPPGS CCCCHHCCCCCCCCC	15.26	28985074
24	Phosphorylation	PHYRYGMSPPGSVAD CHHCCCCCCCCCHHH	24.47	25159151
93	Phosphorylation	VVVGGLNTHYRYIGK EEECCCCCEEEECCC	25.90	20068231
95	Phosphorylation	VGGLNTHYRYIGKTM ECCCCCEEEECCCCC	11.76	20068231
97	Phosphorylation	GLNTHYRYIGKTMDY CCCCEEEECCCCCCC	13.58	-
100	Ubiquitination	THYRYIGKTMDYRGT CEEEECCCCCCCCCC	30.99	-
101	Phosphorylation	HYRYIGKTMDYRGTM EEEECCCCCCCCCCC	15.29	20068231
104	Phosphorylation	YIGKTMDYRGTMIPS ECCCCCCCCCCCCCC	10.50	20068231
107	Phosphorylation	KTMDYRGTMIPSEAP CCCCCCCCCCCCCHH	11.70	20068231
128	Methylation	KLVDPMDRKPTEIEW EECCCCCCCCCEEEE	40.37	115483747
129	Ubiquitination	LVDPMDRKPTEIEWR ECCCCCCCCCEEEEE	52.61	-
147	Phosphorylation	AGERVRVSTRSGRII CCCEEEEEECCCCEE	13.92	20068231
148	Phosphorylation	GERVRVSTRSGRIIP CCEEEEEECCCCEEC	26.46	20068231
150	Phosphorylation	RVRVSTRSGRIIPKP EEEEEECCCCEECCC	32.29	-
156	Ubiquitination	RSGRIIPKPEFPRAD CCCCEECCCCCCCCC	46.93	29967540
175	Ubiquitination	ETWIDGPKDTSVEDA CCCCCCCCCCCHHHH	78.24	29967540
177	Phosphorylation	WIDGPKDTSVEDALE CCCCCCCCCHHHHHH	40.58	26471730
178	Phosphorylation	IDGPKDTSVEDALER CCCCCCCCHHHHHHH	33.37	24719451
193	Phosphorylation	TYVPCLKTLQEEVME HHHHHHHHHHHHHHH	22.26	20068231
207	Phosphorylation	EAMGIKETRKYKKVY HHHCCHHHHCCCEEE	27.71	26437602
216	Phosphorylation	KYKKVYWY------- CCCEEECC-------	7.32	18083107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RM24_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RM24_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RM24_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
RM44_HUMAN	MRPL44	physical	22939629
RM37_HUMAN	MRPL37	physical	22939629
RM39_HUMAN	MRPL39	physical	22939629
RM40_HUMAN	MRPL40	physical	22939629
RM51_HUMAN	MRPL51	physical	22939629
RT05_HUMAN	MRPS5	physical	22939629
TM177_HUMAN	TMEM177	physical	22939629
TSR1_HUMAN	TSR1	physical	22939629
RS15_HUMAN	RPS15	physical	22939629
RM28_HUMAN	MRPL28	physical	26344197
RM38_HUMAN	MRPL38	physical	26344197
RM46_HUMAN	MRPL46	physical	26344197
RM09_HUMAN	MRPL9	physical	26344197
RT10_HUMAN	MRPS10	physical	26344197
RL17_HUMAN	RPL17	physical	26344197
RL8_HUMAN	RPL8	physical	26344197
EFTU_HUMAN	TUFM	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.