| UniProt ID | RM14_HUMAN | |
|---|---|---|
| UniProt AC | Q6P1L8 | |
| Protein Name | 39S ribosomal protein L14, mitochondrial | |
| Gene Name | MRPL14 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 145 | |
| Subcellular Localization | Mitochondrion . | |
| Protein Description | Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable).. | |
| Protein Sequence | MAFFTGLWGPFTCVSRVLSHHCFSTTGSLSAIQKMTRVRVVDNSALGNSPYHRAPRCIHVYKKNGVGKVGDQILLAIKGQKKKALIVGHCMPGPRMTPRFDSNNVVLIEDNGNPVGTRIKTPIPTSLRKREGEYSKVLAIAQNFV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 24 | Phosphorylation | VLSHHCFSTTGSLSA HHHHHCCCCCCCHHH | 30.38 | 30631047 | |
| 36 | Phosphorylation | LSAIQKMTRVRVVDN HHHHHHCCEEEEECC | 32.80 | 30631047 | |
| 44 | Phosphorylation | RVRVVDNSALGNSPY EEEEECCCCCCCCCC | 22.02 | 30266825 | |
| 49 | Phosphorylation | DNSALGNSPYHRAPR CCCCCCCCCCCCCCC | 25.66 | 30266825 | |
| 51 | Phosphorylation | SALGNSPYHRAPRCI CCCCCCCCCCCCCEE | 12.08 | 30266825 | |
| 121 | Phosphorylation | PVGTRIKTPIPTSLR CCCCEEECCCCCCHH | 24.87 | 24114839 | |
| 125 | Phosphorylation | RIKTPIPTSLRKREG EEECCCCCCHHHCCC | 40.90 | 21712546 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RM14_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RM14_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RM14_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| RM40_HUMAN | MRPL40 | physical | 22939629 | |
| RM19_HUMAN | MRPL19 | physical | 22939629 | |
| RM39_HUMAN | MRPL39 | physical | 22939629 | |
| RM38_HUMAN | MRPL38 | physical | 22939629 | |
| RM53_HUMAN | MRPL53 | physical | 22939629 | |
| RT14_HUMAN | MRPS14 | physical | 22939629 | |
| RT10_HUMAN | MRPS10 | physical | 22939629 | |
| RM15_HUMAN | MRPL15 | physical | 22939629 | |
| RM22_HUMAN | MRPL22 | physical | 22939629 | |
| RM16_HUMAN | MRPL16 | physical | 22939629 | |
| SARNP_HUMAN | SARNP | physical | 22939629 | |
| SRPRB_HUMAN | SRPRB | physical | 22939629 | |
| RS20_HUMAN | RPS20 | physical | 22939629 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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