RM15_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RM15_HUMAN
• UniProt AC: Q9P015
• Protein Name: 39S ribosomal protein L15, mitochondrial
• Gene Name: MRPL15
• Organism: Homo sapiens (Human).
• Sequence Length: 296
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MAGPLQGGGARALDLLRGLPRVSLANLKPNPGSKKPERRPRGRRRGRKCGRGHKGERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRRQYKPLSLNRLQYLIDLGRVDPSQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFTAKVNIEVQLASELAIAAIEKNGGVVTTAFYDPRSLDIVCKPVPFFLRGQPIPKRMLPPEELVPYYTDAKNRGYLADPAKFPEARLELARKYGYILPDITKDELFKMLCTRKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYTS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Methylation	ARALDLLRGLPRVSL HHHHHHHCCCCCEEE	52.48	115483715
23	Phosphorylation	LRGLPRVSLANLKPN HCCCCCEEECCCCCC	24.04	21406692
28	Ubiquitination	RVSLANLKPNPGSKK CEEECCCCCCCCCCC	42.42	21890473
33	Phosphorylation	NLKPNPGSKKPERRP CCCCCCCCCCCCCCC	38.47	20068231
34	Ubiquitination	LKPNPGSKKPERRPR CCCCCCCCCCCCCCC	77.57	21963094
35	Ubiquitination	KPNPGSKKPERRPRG CCCCCCCCCCCCCCC	54.53	21963094
80	Ubiquitination	PFYIRIPKYGFNEGH CEEEEECCCCCCCCC	56.48	22817900
93	Phosphorylation	GHSFRRQYKPLSLNR CCCHHHHCCCCCHHH	16.86	21406692
97	Phosphorylation	RRQYKPLSLNRLQYL HHHCCCCCHHHHHHH	31.93	21406692
103	Phosphorylation	LSLNRLQYLIDLGRV CCHHHHHHHHHHCCC	15.37	-
128	Phosphorylation	LVNGRGVTIQPLKRD HCCCCCCEEEECCCH	19.40	20068231
133	Ubiquitination	GVTIQPLKRDYGVQL CCEEEECCCHHCEEE	50.32	-
160	Phosphorylation	NIEVQLASELAIAAI CEEHHHHHHHHHHHH	41.56	-
175	Phosphorylation	EKNGGVVTTAFYDPR HHCCCEEEEEEECCC	15.25	20068231
176	Phosphorylation	KNGGVVTTAFYDPRS HCCCEEEEEEECCCC	11.80	20068231
179	Phosphorylation	GVVTTAFYDPRSLDI CEEEEEEECCCCCEE	23.67	20068231
189	Ubiquitination	RSLDIVCKPVPFFLR CCCEEEEEECCCCCC	37.85	-
228	Ubiquitination	GYLADPAKFPEARLE CCCCCHHHCHHHHHH	67.83	29967540
239	Ubiquitination	ARLELARKYGYILPD HHHHHHHHHCCCCCC	37.10	-
281	Ubiquitination	VVNMADKKILKPTDE EEECCCCCCCCCCCC	54.54	29967540
281	Malonylation	VVNMADKKILKPTDE EEECCCCCCCCCCCC	54.54	26320211
286	Phosphorylation	DKKILKPTDENLLKY CCCCCCCCCCCHHHH	55.12	-
292	Ubiquitination	PTDENLLKYYTS--- CCCCCHHHHHCC---	39.10	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RM15_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RM15_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RM15_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RM16_HUMAN	MRPL16	physical	22939629
RM39_HUMAN	MRPL39	physical	22939629
RM38_HUMAN	MRPL38	physical	22939629
RM19_HUMAN	MRPL19	physical	22939629
RM40_HUMAN	MRPL40	physical	22939629
RM32_HUMAN	MRPL32	physical	22939629
RM50_HUMAN	MRPL50	physical	22939629
RM55_HUMAN	MRPL55	physical	22939629
TM177_HUMAN	TMEM177	physical	22939629
SCFD1_HUMAN	SCFD1	physical	22939629
RT63_HUMAN	MRPL57	physical	22939629
RM20_HUMAN	MRPL20	physical	26344197
RM38_HUMAN	MRPL38	physical	26344197
RS14_HUMAN	RPS14	physical	26344197
RS2_HUMAN	RPS2	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.