RM27_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RM27_HUMAN
• UniProt AC: Q9P0M9
• Protein Name: 39S ribosomal protein L27, mitochondrial
• Gene Name: MRPL27
• Organism: Homo sapiens (Human).
• Sequence Length: 148
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MASVVLALRTRTAVTSLLSPTPATALAVRYASKKSGGSSKNLGGKSSGRRQGIKKMEGHYVHAGNIIATQRHFRWHPGAHVGVGKNKCLYALEEGIVRYTKEVYVPHPRNTEAVDLITRLPKGAVLYKTFVHVVPAKPEGTFKLVAML

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	LRTRTAVTSLLSPTP HHHHHHHHHHCCCCH	15.93	-
16	Phosphorylation	RTRTAVTSLLSPTPA HHHHHHHHHCCCCHH	22.25	-
19	Phosphorylation	TAVTSLLSPTPATAL HHHHHHCCCCHHHHH	31.83	30576142
32	Phosphorylation	ALAVRYASKKSGGSS HHHHHHHHHHCCCCC	31.51	30576142
45	Ubiquitination	SSKNLGGKSSGRRQG CCCCCCCCCCCCHHC	39.38	29967540
46	Phosphorylation	SKNLGGKSSGRRQGI CCCCCCCCCCCHHCE	41.10	23911959
47	Phosphorylation	KNLGGKSSGRRQGIK CCCCCCCCCCHHCEE	39.54	23911959
85	Ubiquitination	GAHVGVGKNKCLYAL CCEEECCCCHHHHHH	51.32	29967540
87	Ubiquitination	HVGVGKNKCLYALEE EEECCCCHHHHHHHH	29.15	29967540
101	Ubiquitination	EGIVRYTKEVYVPHP HCCEEEEEEEECCCC	35.93	29967540
122	Ubiquitination	DLITRLPKGAVLYKT HHHHHCCCCCEEEEE	65.18	22817900
122	Malonylation	DLITRLPKGAVLYKT HHHHHCCCCCEEEEE	65.18	26320211
137	Ubiquitination	FVHVVPAKPEGTFKL EEEEEECCCCCCEEE	37.22	29967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RM27_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RM27_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RM27_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.