RM17_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RM17_HUMAN
• UniProt AC: Q9NRX2
• Protein Name: 39S ribosomal protein L17, mitochondrial
• Gene Name: MRPL17
• Organism: Homo sapiens (Human).
• Sequence Length: 175
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MRLSVAAAISHGRVFRRMGLGPESRIHLLRNLLTGLVRHERIEAPWARVDEMRGYAEKLIDYGKLGDTNERAMRMADFWLTEKDLIPKLFQVLAPRYKDQTGGYTRMLQIPNRSLDRAKMAVIEYKGNCLPPLPLPRRDSHLTLLNQLLQGLRQDLRQSQEASNHSSHTAQTPGI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MRLSVAAAISH ----CCHHHHHHHHC	10.19	23684312
10	Phosphorylation	LSVAAAISHGRVFRR HHHHHHHHCCHHHHH	18.37	23684312
34	Phosphorylation	HLLRNLLTGLVRHER HHHHHHHHHHHHHHC	31.47	-
55	Phosphorylation	RVDEMRGYAEKLIDY CHHHHHHHHHHHHHH	10.96	22817900
58	2-Hydroxyisobutyrylation	EMRGYAEKLIDYGKL HHHHHHHHHHHHHCC	42.44	-
58	Acetylation	EMRGYAEKLIDYGKL HHHHHHHHHHHHHCC	42.44	25953088
64	Ubiquitination	EKLIDYGKLGDTNER HHHHHHHCCCCHHHH	42.96	29967540
64	2-Hydroxyisobutyrylation	EKLIDYGKLGDTNER HHHHHHHCCCCHHHH	42.96	-
97	Phosphorylation	FQVLAPRYKDQTGGY HHHHHHHHCCCCCCE	20.18	-
101	Phosphorylation	APRYKDQTGGYTRML HHHHCCCCCCEEEEE	42.58	-
104	Phosphorylation	YKDQTGGYTRMLQIP HCCCCCCEEEEEECC	7.78	22461510
105	Phosphorylation	KDQTGGYTRMLQIPN CCCCCCEEEEEECCC	16.93	22461510
129	Glutathionylation	VIEYKGNCLPPLPLP EEEECCCCCCCCCCC	9.11	22555962
140	Phosphorylation	LPLPRRDSHLTLLNQ CCCCCHHHHHHHHHH	20.70	28450419
143	Phosphorylation	PRRDSHLTLLNQLLQ CCHHHHHHHHHHHHH	24.63	26434776
172	Phosphorylation	HSSHTAQTPGI---- CCCCCCCCCCC----	22.48	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RM17_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RM17_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RM17_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RS23_HUMAN	RPS23	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.