RM49_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RM49_HUMAN
• UniProt AC: Q13405
• Protein Name: 39S ribosomal protein L49, mitochondrial
• Gene Name: MRPL49
• Organism: Homo sapiens (Human).
• Sequence Length: 166
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MAATMFRATLRGWRTGVQRGCGLRLLSQTQGPPDYPRFVESVDEYQFVERLLPATRIPDPPKHEHYPTPSGWQPPRDPPPNLPYFVRRSRMHNIPVYKDITHGNRQMTVIRKVEGDIWALQKDVEDFLSPLLGKTPVTQVNEVTGTLRIKGYFDQELKAWLLEKGF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MAATMFRATLR ----CCCHHHHHHHH	13.80	24043423
9	Phosphorylation	AATMFRATLRGWRTG CCHHHHHHHHHHHHH	16.84	24043423
27	Phosphorylation	GCGLRLLSQTQGPPD CCCCHHHHCCCCCCC	35.46	26074081
29	Phosphorylation	GLRLLSQTQGPPDYP CCHHHHCCCCCCCCH	31.92	26074081
35	Phosphorylation	QTQGPPDYPRFVESV CCCCCCCCHHHHCCC	11.33	26074081
41	Phosphorylation	DYPRFVESVDEYQFV CCHHHHCCCHHHHHH	29.57	26074081
45	Phosphorylation	FVESVDEYQFVERLL HHCCCHHHHHHHHHC	11.64	26074081
55	Phosphorylation	VERLLPATRIPDPPK HHHHCCCCCCCCCCC	27.47	26074081
66	Phosphorylation	DPPKHEHYPTPSGWQ CCCCCCCCCCCCCCC	13.05	28634298
68	Phosphorylation	PKHEHYPTPSGWQPP CCCCCCCCCCCCCCC	23.95	28634298
70	Phosphorylation	HEHYPTPSGWQPPRD CCCCCCCCCCCCCCC	55.96	28634298
101	Phosphorylation	IPVYKDITHGNRQMT CCEEECCCCCCEEEE	33.59	20068231
129	Phosphorylation	KDVEDFLSPLLGKTP CCHHHHHHHHHCCCC	17.31	-
134	Ubiquitination	FLSPLLGKTPVTQVN HHHHHHCCCCCCEEE	50.02	-
135	Phosphorylation	LSPLLGKTPVTQVNE HHHHHCCCCCCEEEE	22.61	20068231
138	Phosphorylation	LLGKTPVTQVNEVTG HHCCCCCCEEEECCC	28.18	20068231
144	Phosphorylation	VTQVNEVTGTLRIKG CCEEEECCCEEEEEE	20.47	20068231
146	Phosphorylation	QVNEVTGTLRIKGYF EEEECCCEEEEEEEE	11.96	20068231
150	2-Hydroxyisobutyrylation	VTGTLRIKGYFDQEL CCCEEEEEEEECHHH	40.92	-
152	Phosphorylation	GTLRIKGYFDQELKA CEEEEEEEECHHHHH	10.05	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RM49_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RM49_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RM49_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
RM52_HUMAN	MRPL52	physical	22939629
TM177_HUMAN	TMEM177	physical	22939629
SCFD1_HUMAN	SCFD1	physical	22939629
TIM10_HUMAN	TIMM10	physical	22939629

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.