RM52_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RM52_HUMAN
• UniProt AC: Q86TS9
• Protein Name: 39S ribosomal protein L52, mitochondrial
• Gene Name: MRPL52
• Organism: Homo sapiens (Human).
• Sequence Length: 123
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MAALGTVLFTGVRRLHCSVAAWAGGQWRLQQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAERETFARRVVLLSQEMDAGLQAWQLRQQKLQEEQRKQENALKPKGASLKSPLPSQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MAALGTVLFTGVR --CCCHHHHHHHCCC	18.19	-
10	Phosphorylation	ALGTVLFTGVRRLHC CHHHHHHHCCCHHHH	30.52	24719451
61	Acetylation	GRPAPPMKGQLRRKA CCCCCCCCCHHHHHH	49.64	11792789
68 (in isoform 4)	Phosphorylation	-	21.19	-
97	Acetylation	AWQLRQQKLQEEQRK HHHHHHHHHHHHHHH	43.74	25953088
115	Phosphorylation	ALKPKGASLKSPLPS CCCCCCCCCCCCCCC	45.02	20068231
118	Phosphorylation	PKGASLKSPLPSQ-- CCCCCCCCCCCCC--	36.64	27050516
122	Phosphorylation	SLKSPLPSQ------ CCCCCCCCC------	57.09	20068231

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RM52_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RM52_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RM52_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
RM55_HUMAN	MRPL55	physical	22939629
TM177_HUMAN	TMEM177	physical	22939629
TSR1_HUMAN	TSR1	physical	22939629
RS18_HUMAN	RPS18	physical	22939629

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.