PR40A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PR40A_HUMAN
• UniProt AC: O75400
• Protein Name: Pre-mRNA-processing factor 40 homolog A
• Gene Name: PRPF40A
• Organism: Homo sapiens (Human).
• Sequence Length: 957
• Subcellular Localization: Nucleus speckle. Nucleus matrix . Colocalizes with AKAP8L in the nuclear matrix..
• Protein Description: Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing..
• Protein Sequence: MRPGTGAERGGLMVSEMESHPPSQGPGDGERRLSGSSLCSGSWVSADGFLRRRPSMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPPMGGPPMGQMPGMMSSVMPGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Methylation	------MRPGTGAER ------CCCCCCCCC	38.05	-
5 (in isoform 2)	Phosphorylation	-	35.58	20860994
5 (in isoform 5)	Phosphorylation	-	35.58	20860994
9	Methylation	RPGTGAERGGLMVSE CCCCCCCCCCEEEEE	43.90	-
10 (in isoform 2)	Phosphorylation	-	25.70	28348404
10 (in isoform 5)	Phosphorylation	-	25.70	28348404
11 (in isoform 2)	Phosphorylation	-	19.47	20873877
11 (in isoform 5)	Phosphorylation	-	19.47	20873877
13 (in isoform 2)	Phosphorylation	-	3.35	20873877
13 (in isoform 5)	Phosphorylation	-	3.35	20873877
15 (in isoform 2)	Phosphorylation	-	19.77	20873877
15 (in isoform 5)	Phosphorylation	-	19.77	20873877
17 (in isoform 2)	Methylation	-	5.08	24129315
17 (in isoform 5)	Methylation	-	5.08	24129315
20 (in isoform 2)	Phosphorylation	-	25.61	20873877
20 (in isoform 5)	Phosphorylation	-	25.61	20873877
23	Phosphorylation	EMESHPPSQGPGDGE ECCCCCCCCCCCCCC	52.82	28555341
24 (in isoform 2)	Methylation	-	68.80	24129315
24 (in isoform 5)	Methylation	-	68.80	24129315
34	Phosphorylation	GDGERRLSGSSLCSG CCCCCCCCCCCCCCC	34.51	30266825
36	Phosphorylation	GERRLSGSSLCSGSW CCCCCCCCCCCCCCE	19.43	30266825
37	Phosphorylation	ERRLSGSSLCSGSWV CCCCCCCCCCCCCEE	36.60	30266825
40	Phosphorylation	LSGSSLCSGSWVSAD CCCCCCCCCCEECCC	40.95	30266825
42	Phosphorylation	GSSLCSGSWVSADGF CCCCCCCCEECCCCC	14.17	30266825
45	Phosphorylation	LCSGSWVSADGFLRR CCCCCEECCCCCCCC	17.87	20068231
47 (in isoform 2)	Methylation	-	40.65	24129315
47 (in isoform 5)	Methylation	-	40.65	24129315
49	Phosphorylation	SWVSADGFLRRRPSM CEECCCCCCCCCCCC	5.02	32142685
51	Methylation	VSADGFLRRRPSMGH ECCCCCCCCCCCCCC	30.24	-
52	Phosphorylation	SADGFLRRRPSMGHP CCCCCCCCCCCCCCC	57.94	32645325
55	Phosphorylation	GFLRRRPSMGHPGMH CCCCCCCCCCCCCCC	35.27	24719451
63	Phosphorylation	MGHPGMHYAPMGMHP CCCCCCCCCCCCCCC	11.96	28634298
65	Ubiquitination	HPGMHYAPMGMHPMG CCCCCCCCCCCCCCC	16.82	32015554
68	Phosphorylation	MHYAPMGMHPMGQRA CCCCCCCCCCCCCCC	2.33	32645325
74	Methylation	GMHPMGQRANMPPVP CCCCCCCCCCCCCCC	23.38	-
81	Ubiquitination	RANMPPVPHGMMPQM CCCCCCCCCCCCCCC	24.88	32015554
85	Ubiquitination	PPVPHGMMPQMMPPM CCCCCCCCCCCCCCC	2.17	33845483
97	Ubiquitination	PPMGGPPMGQMPGMM CCCCCCCCCCCCCHH	7.01	32015554
101	Ubiquitination	GPPMGQMPGMMSSVM CCCCCCCCCHHHHHC	21.46	33845483
108	Ubiquitination	PGMMSSVMPGMMMSH CCHHHHHCCHHHHHH	2.28	23000965
113	Ubiquitination	SVMPGMMMSHMSQAS HHCCHHHHHHHHHHH	1.52	23000965
117 (in isoform 2)	Phosphorylation	-	19.71	27251275
120	Phosphorylation	MSHMSQASMQPALPP HHHHHHHHCCCCCCC	15.43	19651622
120 (in isoform 2)	Phosphorylation	-	15.43	27251275
124	Phosphorylation	SQASMQPALPPGVNS HHHHCCCCCCCCCCC	18.79	32645325
124 (in isoform 2)	Phosphorylation	-	18.79	24719451
134	Ubiquitination	PGVNSMDVAAGTASG CCCCCCCHHCCCCCC	2.70	32015554
137	Ubiquitination	NSMDVAAGTASGAKS CCCCHHCCCCCCCCC	16.45	32015554
144	Phosphorylation	GTASGAKSMWTEHKS CCCCCCCCCCEEEEC	21.01	23403867
147	Phosphorylation	SGAKSMWTEHKSPDG CCCCCCCEEEECCCC	21.41	23403867
150	Ubiquitination	KSMWTEHKSPDGRTY CCCCEEEECCCCCEE	58.41	32015554
151	Phosphorylation	SMWTEHKSPDGRTYY CCCEEEECCCCCEEE	30.08	23401153
156	Phosphorylation	HKSPDGRTYYYNTET EECCCCCEEEEECCC	22.77	28152594
157	Phosphorylation	KSPDGRTYYYNTETK ECCCCCEEEEECCCC	11.55	28152594
157	Ubiquitination	KSPDGRTYYYNTETK ECCCCCEEEEECCCC	11.55	32015554
158	Phosphorylation	SPDGRTYYYNTETKQ CCCCCEEEEECCCCC	6.93	28152594
164	Ubiquitination	YYYNTETKQSTWEKP EEEECCCCCCCCCCC	35.70	23000965
166	Phosphorylation	YNTETKQSTWEKPDD EECCCCCCCCCCCCC	36.72	32645325
167 (in isoform 2)	Phosphorylation	-	34.84	27251275
169	Acetylation	ETKQSTWEKPDDLKT CCCCCCCCCCCCCCC	55.59	19608861
169	Ubiquitination	ETKQSTWEKPDDLKT CCCCCCCCCCCCCCC	55.59	23000965
169 (in isoform 2)	Acetylation	-	55.59	-
169 (in isoform 2)	Ubiquitination	-	55.59	-
170	Acetylation	TKQSTWEKPDDLKTP CCCCCCCCCCCCCCH	45.36	26051181
176	Phosphorylation	EKPDDLKTPAEQLLS CCCCCCCCHHHHHHH	34.72	28555341
178	Ubiquitination	PDDLKTPAEQLLSKC CCCCCCHHHHHHHCC	23.54	29967540
179	Ubiquitination	DDLKTPAEQLLSKCP CCCCCHHHHHHHCCC	42.86	32015554
183	Phosphorylation	TPAEQLLSKCPWKEY CHHHHHHHCCCCHHC	40.58	24719451
186	Ubiquitination	EQLLSKCPWKEYKSD HHHHHCCCCHHCCCC	49.24	29967540
188	Acetylation	LLSKCPWKEYKSDSG HHHCCCCHHCCCCCC	35.99	26051181
191	Acetylation	KCPWKEYKSDSGKPY CCCCHHCCCCCCCCC	49.21	26051181
191	Sumoylation	KCPWKEYKSDSGKPY CCCCHHCCCCCCCCC	49.21	28112733
192	Phosphorylation	CPWKEYKSDSGKPYY CCCHHCCCCCCCCCC	35.79	27251275
194	Phosphorylation	WKEYKSDSGKPYYYN CHHCCCCCCCCCCCC	56.67	25159151
196	Acetylation	EYKSDSGKPYYYNSQ HCCCCCCCCCCCCCC	33.52	19608861
196	Ubiquitination	EYKSDSGKPYYYNSQ HCCCCCCCCCCCCCC	33.52	21906983
196 (in isoform 1)	Ubiquitination	-	33.52	21890473
196 (in isoform 3)	Ubiquitination	-	33.52	21890473
198	Phosphorylation	KSDSGKPYYYNSQTK CCCCCCCCCCCCCCC	23.28	28152594
199	Phosphorylation	SDSGKPYYYNSQTKE CCCCCCCCCCCCCCC	12.51	28152594
199	Ubiquitination	SDSGKPYYYNSQTKE CCCCCCCCCCCCCCC	12.51	33845483
200	Phosphorylation	DSGKPYYYNSQTKES CCCCCCCCCCCCCCC	11.51	28152594
202	Phosphorylation	GKPYYYNSQTKESRW CCCCCCCCCCCCCCC	24.09	28152594
204	Phosphorylation	PYYYNSQTKESRWAK CCCCCCCCCCCCCCC	36.28	28152594
206	Ubiquitination	YYNSQTKESRWAKPK CCCCCCCCCCCCCCC	49.26	32015554
207	O-linked_Glycosylation	YNSQTKESRWAKPKE CCCCCCCCCCCCCCH	34.38	23301498
211	Ubiquitination	TKESRWAKPKELEDL CCCCCCCCCCHHHCC	50.06	32015554
221	Phosphorylation	ELEDLEGYQNTIVAG HHHCCCCCCCEEEEC	6.82	27642862
233 (in isoform 2)	Ubiquitination	-	30.28	21890473
241	Sumoylation	SNLHAMIKAEESSKQ HHHHHHHHHHHHHCC	36.34	-
241	Sumoylation	SNLHAMIKAEESSKQ HHHHHHHHHHHHHCC	36.34	28112733
248	Ubiquitination	KAEESSKQEECTTTS HHHHHHCCCCCCCCC	54.38	32015554
270	Ubiquitination	EIPTTMSTMAAAEAA CCCCCHHHHHHHHHH	10.45	23000965
275	Ubiquitination	MSTMAAAEAAAAVVA HHHHHHHHHHHHHHH	33.83	23000965
319	Ubiquitination	VVPEPEVTSIVATVV CCCCCCEEEEEEEEE	15.86	23503661
321	Ubiquitination	PEPEVTSIVATVVDN CCCCEEEEEEEEECC	1.46	32015554
337	Ubiquitination	NTVTISTEEQAQLTS CEEEEEHHHHHHHCC	41.12	23503661
341	Phosphorylation	ISTEEQAQLTSTPAI EEHHHHHHHCCCCCC	44.99	17081983
341 (in isoform 2)	Phosphorylation	-	44.99	-
344	Phosphorylation	EEQAQLTSTPAIQDQ HHHHHHCCCCCCCCC	40.77	26074081
345	Phosphorylation	EQAQLTSTPAIQDQS HHHHHCCCCCCCCCC	16.11	26074081
346	Phosphorylation	QAQLTSTPAIQDQSV HHHHCCCCCCCCCCE	27.42	19664994
346 (in isoform 2)	Phosphorylation	-	27.42	24719451
352	Phosphorylation	TPAIQDQSVEVSSNT CCCCCCCCEEEECCC	28.65	24275569
356	Phosphorylation	QDQSVEVSSNTGEET CCCCEEEECCCCCCC	12.36	24275569
358	Ubiquitination	QSVEVSSNTGEETSK CCEEEECCCCCCCCC	44.59	24816145
366	Ubiquitination	TGEETSKQETVADFT CCCCCCCCEEECCCC	51.89	29967540
368	Phosphorylation	EETSKQETVADFTPK CCCCCCEEECCCCCC	20.64	29255136
373	Phosphorylation	QETVADFTPKKEEEE CEEECCCCCCHHHHC	34.44	19664994
375	Sumoylation	TVADFTPKKEEEESQ EECCCCCCHHHHCCC	70.52	-
375	Acetylation	TVADFTPKKEEEESQ EECCCCCCHHHHCCC	70.52	26051181
375	Sumoylation	TVADFTPKKEEEESQ EECCCCCCHHHHCCC	70.52	28112733
375	Ubiquitination	TVADFTPKKEEEESQ EECCCCCCHHHHCCC	70.52	33845483
376	Sumoylation	VADFTPKKEEEESQP ECCCCCCHHHHCCCC	72.12	28112733
376	Ubiquitination	VADFTPKKEEEESQP ECCCCCCHHHHCCCC	72.12	24816145
377	Ubiquitination	ADFTPKKEEEESQPA CCCCCCHHHHCCCCC	76.42	33845483
381	Phosphorylation	PKKEEEESQPAKKTY CCHHHHCCCCCCCCC	44.75	24732914
393	Acetylation	KTYTWNTKEEAKQAF CCCCCCCHHHHHHHH	50.79	26051181
393	Ubiquitination	KTYTWNTKEEAKQAF CCCCCCCHHHHHHHH	50.79	33845483
393 (in isoform 2)	Ubiquitination	-	50.79	-
401	Acetylation	EEAKQAFKELLKEKR HHHHHHHHHHHHHCC	50.93	26822725
406	Ubiquitination	AFKELLKEKRVPSNA HHHHHHHHCCCCCCC	46.17	29967540
411	Phosphorylation	LKEKRVPSNASWEQA HHHCCCCCCCCHHHH	42.02	21406692
414	Phosphorylation	KRVPSNASWEQAMKM CCCCCCCCHHHHHHH	35.08	21406692
414	Ubiquitination	KRVPSNASWEQAMKM CCCCCCCCHHHHHHH	35.08	24816145
416	Ubiquitination	VPSNASWEQAMKMII CCCCCCHHHHHHHHH	26.43	33845483
417	Ubiquitination	PSNASWEQAMKMIIN CCCCCHHHHHHHHHC	40.26	32015554
418	Ubiquitination	SNASWEQAMKMIIND CCCCHHHHHHHHHCC	6.50	33845483
429	Phosphorylation	IINDPRYSALAKLSE HHCCHHHHHHHHHHH	20.34	25159151
431	Ubiquitination	NDPRYSALAKLSEKK CCHHHHHHHHHHHHH	3.38	33845483
432	Ubiquitination	DPRYSALAKLSEKKQ CHHHHHHHHHHHHHH	15.51	24816145
433	Acetylation	PRYSALAKLSEKKQA HHHHHHHHHHHHHHH	54.09	25953088
433	Malonylation	PRYSALAKLSEKKQA HHHHHHHHHHHHHHH	54.09	26320211
434	Ubiquitination	RYSALAKLSEKKQAF HHHHHHHHHHHHHHH	7.13	33845483
435	Phosphorylation	YSALAKLSEKKQAFN HHHHHHHHHHHHHHH	46.81	29214152
435	Ubiquitination	YSALAKLSEKKQAFN HHHHHHHHHHHHHHH	46.81	32015554
437	Ubiquitination	ALAKLSEKKQAFNAY HHHHHHHHHHHHHHH	46.97	29967540
449	Ubiquitination	NAYKVQTEKEEKEEA HHHHCCCHHHHHHHH	41.18	33845483
450	Acetylation	AYKVQTEKEEKEEAR HHHCCCHHHHHHHHH	74.65	23749302
460	Phosphorylation	KEEARSKYKEAKESF HHHHHHHHHHHHHHH	18.46	29759185
464	2-Hydroxyisobutyrylation	RSKYKEAKESFQRFL HHHHHHHHHHHHHHH	55.79	-
472	Ubiquitination	ESFQRFLENHEKMTS HHHHHHHHHHHHHCC	54.55	33845483
473	Ubiquitination	SFQRFLENHEKMTST HHHHHHHHHHHHCCC	51.25	33845483
476	Acetylation	RFLENHEKMTSTTRY HHHHHHHHHCCCCHH	39.67	25953088
478	Phosphorylation	LENHEKMTSTTRYKK HHHHHHHCCCCHHHH	33.71	-
479	Phosphorylation	ENHEKMTSTTRYKKA HHHHHHCCCCHHHHH	25.04	-
481	Ubiquitination	HEKMTSTTRYKKAEQ HHHHCCCCHHHHHHH	31.59	23503661
489	Ubiquitination	RYKKAEQMFGEMEVW HHHHHHHHHHHHHHH	3.33	24816145
490	Ubiquitination	YKKAEQMFGEMEVWN HHHHHHHHHHHHHHH	8.18	33845483
491	Ubiquitination	KKAEQMFGEMEVWNA HHHHHHHHHHHHHHH	28.18	33845483
499	Ubiquitination	EMEVWNAISERDRLE HHHHHHHCCHHHHHH	3.87	23503661
507	Ubiquitination	SERDRLEIYEDVLFF CHHHHHHHHHHHHHH	5.59	24816145
514	Ubiquitination	IYEDVLFFLSKKEKE HHHHHHHHHCHHHHH	7.05	33845483
520	Ubiquitination	FFLSKKEKEQAKQLR HHHCHHHHHHHHHHH	65.10	24816145
532	Ubiquitination	QLRKRNWEALKNILD HHHHHHHHHHHHHHH	47.90	33845483
537	Ubiquitination	NWEALKNILDNMANV HHHHHHHHHHHHCCC	4.96	24816145
538	Ubiquitination	WEALKNILDNMANVT HHHHHHHHHHHCCCC	5.64	24816145
545	Ubiquitination	LDNMANVTYSTTWSE HHHHCCCCEECCHHH	16.15	24816145
555	Ubiquitination	TTWSEAQQYLMDNPT CCHHHHHHHHHHCCC	40.13	24816145
563	Ubiquitination	YLMDNPTFAEDEELQ HHHHCCCCCCHHHHH	8.06	24816145
568	Ubiquitination	PTFAEDEELQNMDKE CCCCCHHHHHCCCHH	68.90	33845483
572	Ubiquitination	EDEELQNMDKEDALI CHHHHHCCCHHHHHH	5.13	27667366
574	Ubiquitination	EELQNMDKEDALICF HHHHCCCHHHHHHHH	46.88	33845483
586	Ubiquitination	ICFEEHIRALEKEEE HHHHHHHHHHHHHHH	34.72	33845483
590	Ubiquitination	EHIRALEKEEEEEKQ HHHHHHHHHHHHHHH	71.87	33845483
596	Ubiquitination	EKEEEEEKQKSLLRE HHHHHHHHHHHHHHH	67.32	-
599	Phosphorylation	EEEEKQKSLLRERRR HHHHHHHHHHHHHHH	30.09	29214152
613	Phosphorylation	RQRKNRESFQIFLDE HHHHCHHHHHHHHHH	21.15	27422710
617	Ubiquitination	NRESFQIFLDELHEH CHHHHHHHHHHHHHH	4.97	21890473
621	Ubiquitination	FQIFLDELHEHGQLH HHHHHHHHHHHCCCC	6.00	21890473
623	Ubiquitination	IFLDELHEHGQLHSM HHHHHHHHHCCCCCC	63.44	33845483
624	Ubiquitination	FLDELHEHGQLHSMS HHHHHHHHCCCCCCC	20.67	33845483
626	Ubiquitination	DELHEHGQLHSMSSW HHHHHHCCCCCCCHH	37.60	23000965
628	Ubiquitination	LHEHGQLHSMSSWME HHHHCCCCCCCHHHH	17.36	33845483
630	Ubiquitination	EHGQLHSMSSWMELY HHCCCCCCCHHHHHC	2.27	21890473
632	Ubiquitination	GQLHSMSSWMELYPT CCCCCCCHHHHHCCC	23.07	33845483
635	Ubiquitination	HSMSSWMELYPTISS CCCCHHHHHCCCCCC	38.60	21890473
639	Ubiquitination	SWMELYPTISSDIRF HHHHHCCCCCCCCCH	21.67	21890473
642	Ubiquitination	ELYPTISSDIRFTNM HHCCCCCCCCCHHCC	32.95	32015554
644	Ubiquitination	YPTISSDIRFTNMLG CCCCCCCCCHHCCCC	4.16	23000965
646	Ubiquitination	TISSDIRFTNMLGQP CCCCCCCHHCCCCCC	6.22	33845483
647	Phosphorylation	ISSDIRFTNMLGQPG CCCCCCHHCCCCCCC	15.18	-
648	Ubiquitination	SSDIRFTNMLGQPGS CCCCCHHCCCCCCCC	22.44	23000965
651	Ubiquitination	IRFTNMLGQPGSTAL CCHHCCCCCCCCHHH	22.37	24816145
651 (in isoform 3)	Ubiquitination	-	22.37	21890473
653	Acetylation	FTNMLGQPGSTALDL HHCCCCCCCCHHHHH	36.58	19608861
653 (in isoform 2)	Acetylation	-	36.58	-
655	Phosphorylation	NMLGQPGSTALDLFK CCCCCCCCHHHHHHH	19.72	-
666	Ubiquitination	DLFKFYVEDLKARYH HHHHHHHHHHHHHHC	46.37	33845483
669	2-Hydroxyisobutyrylation	KFYVEDLKARYHDEK HHHHHHHHHHHCCHH	43.04	-
669	Ubiquitination	KFYVEDLKARYHDEK HHHHHHHHHHHCCHH	43.04	24816145
669 (in isoform 1)	Ubiquitination	-	43.04	21890473
670	Ubiquitination	FYVEDLKARYHDEKK HHHHHHHHHHCCHHH	25.26	33845483
673	Ubiquitination	EDLKARYHDEKKIIK HHHHHHHCCHHHHHH	31.06	21890473
675	Ubiquitination	LKARYHDEKKIIKDI HHHHHCCHHHHHHHH	42.83	33845483
677	Ubiquitination	ARYHDEKKIIKDILK HHHCCHHHHHHHHHH	47.84	21890473
679	Ubiquitination	YHDEKKIIKDILKDK HCCHHHHHHHHHHCC	4.50	24816145
680	Acetylation	HDEKKIIKDILKDKG CCHHHHHHHHHHCCC	42.04	26051181
681	Ubiquitination	DEKKIIKDILKDKGF CHHHHHHHHHHCCCE	40.83	33845483
682	Ubiquitination	EKKIIKDILKDKGFV HHHHHHHHHHCCCEE	4.35	23000965
684	Acetylation	KIIKDILKDKGFVVE HHHHHHHHCCCEEEE	58.70	26051181
684	Ubiquitination	KIIKDILKDKGFVVE HHHHHHHHCCCEEEE	58.70	33845483
686	Ubiquitination	IKDILKDKGFVVEVN HHHHHHCCCEEEEEE	53.30	23000965
688	Ubiquitination	DILKDKGFVVEVNTT HHHHCCCEEEEEECC	7.38	33845483
691	Ubiquitination	KDKGFVVEVNTTFED HCCCEEEEEECCHHH	25.42	33845483
691 (in isoform 2)	Ubiquitination	-	25.42	21890473
693	Ubiquitination	KGFVVEVNTTFEDFV CCEEEEEECCHHHHH	21.64	33845483
695	Ubiquitination	FVVEVNTTFEDFVAI EEEEEECCHHHHHHH	21.59	21890473
697	Ubiquitination	VEVNTTFEDFVAIIS EEEECCHHHHHHHHH	48.74	33845483
700	Ubiquitination	NTTFEDFVAIISSTK ECCHHHHHHHHHCCC	6.06	23000965
700 (in isoform 2)	Ubiquitination	-	6.06	21890473
700 (in isoform 3)	Ubiquitination	-	6.06	21890473
704	Ubiquitination	EDFVAIISSTKRSTT HHHHHHHHCCCCCEE	26.33	23000965
706 (in isoform 2)	Ubiquitination	-	24.56	21890473
709	Phosphorylation	IISSTKRSTTLDAGN HHHCCCCCEEECHHH	27.57	20860994
709 (in isoform 3)	Ubiquitination	-	27.57	21890473
715	Ubiquitination	RSTTLDAGNIKLAFN CCEEECHHHHHHHHH	35.74	33845483
718	Ubiquitination	TLDAGNIKLAFNSLL EECHHHHHHHHHHHH	37.45	21890473
718 (in isoform 1)	Ubiquitination	-	37.45	21890473
719	Ubiquitination	LDAGNIKLAFNSLLE ECHHHHHHHHHHHHH	6.11	33845483
723	Phosphorylation	NIKLAFNSLLEKAEA HHHHHHHHHHHHHHH	28.07	27050516
724	Ubiquitination	IKLAFNSLLEKAEAR HHHHHHHHHHHHHHH	8.21	33845483
727	Acetylation	AFNSLLEKAEARERE HHHHHHHHHHHHHHH	52.04	25953088
727	Ubiquitination	AFNSLLEKAEARERE HHHHHHHHHHHHHHH	52.04	21890473
727 (in isoform 1)	Ubiquitination	-	52.04	21890473
728	Ubiquitination	FNSLLEKAEARERER HHHHHHHHHHHHHHH	13.30	32015554
730	Ubiquitination	SLLEKAEAREREREK HHHHHHHHHHHHHHH	24.40	27667366
731	Ubiquitination	LLEKAEAREREREKE HHHHHHHHHHHHHHH	34.70	33845483
733	Ubiquitination	EKAEAREREREKEEA HHHHHHHHHHHHHHH	42.60	33845483
734	Ubiquitination	KAEAREREREKEEAR HHHHHHHHHHHHHHH	61.51	27667366
735	Ubiquitination	AEAREREREKEEARK HHHHHHHHHHHHHHH	67.52	33845483
737	Ubiquitination	AREREREKEEARKMK HHHHHHHHHHHHHHH	68.05	33845483
742	Ubiquitination	REKEEARKMKRKESA HHHHHHHHHHHHHHH	56.68	33845483
746	Ubiquitination	EARKMKRKESAFKSM HHHHHHHHHHHHHHH	50.97	33845483
748	Phosphorylation	RKMKRKESAFKSMLK HHHHHHHHHHHHHHH	41.88	-
748	Ubiquitination	RKMKRKESAFKSMLK HHHHHHHHHHHHHHH	41.88	27667366
749	Ubiquitination	KMKRKESAFKSMLKQ HHHHHHHHHHHHHHH	19.58	33845483
749 (in isoform 2)	Ubiquitination	-	19.58	-
751	Acetylation	KRKESAFKSMLKQAA HHHHHHHHHHHHHHC	34.37	26822725
752	Ubiquitination	RKESAFKSMLKQAAP HHHHHHHHHHHHHCC	23.93	27667366
753	Ubiquitination	KESAFKSMLKQAAPP HHHHHHHHHHHHCCC	5.81	33845483
755	Ubiquitination	SAFKSMLKQAAPPIE HHHHHHHHHHCCCCC	29.29	-
755 (in isoform 2)	Ubiquitination	-	29.29	21890473
757	Phosphorylation	FKSMLKQAAPPIELD HHHHHHHHCCCCCHH	21.98	18669648
757 (in isoform 2)	Phosphorylation	-	21.98	24719451
758 (in isoform 3)	Ubiquitination	-	14.12	21890473
760	Phosphorylation	MLKQAAPPIELDAVW HHHHHCCCCCHHHHH	28.14	15302935
760 (in isoform 2)	Phosphorylation	-	28.14	24719451
764 (in isoform 2)	Ubiquitination	-	26.70	21890473
773	Ubiquitination	VWEDIRERFVKEPAF HHHHHHHHHCCCCCC	31.63	33845483
776	2-Hydroxyisobutyrylation	DIRERFVKEPAFEDI HHHHHHCCCCCCCCC	56.09	-
776	Acetylation	DIRERFVKEPAFEDI HHHHHHCCCCCCCCC	56.09	26051181
776	Ubiquitination	DIRERFVKEPAFEDI HHHHHHCCCCCCCCC	56.09	2190698
776 (in isoform 1)	Ubiquitination	-	56.09	21890473
777	Ubiquitination	IRERFVKEPAFEDIT HHHHHCCCCCCCCCC	36.24	33845483
779	Ubiquitination	ERFVKEPAFEDITLE HHHCCCCCCCCCCCH	22.88	21890473
782 (in isoform 2)	Phosphorylation	-	32.49	27251275
783	Ubiquitination	KEPAFEDITLESERK CCCCCCCCCCHHHHH	3.59	21890473
784	Phosphorylation	EPAFEDITLESERKR CCCCCCCCCHHHHHH	36.47	30266825
787	Phosphorylation	FEDITLESERKRIFK CCCCCCHHHHHHHHH	45.90	30266825
788	Ubiquitination	EDITLESERKRIFKD CCCCCHHHHHHHHHH	53.50	21890473
791	Ubiquitination	TLESERKRIFKDFMH CCHHHHHHHHHHHHH	45.88	33845483
792	Ubiquitination	LESERKRIFKDFMHV CHHHHHHHHHHHHHH	5.89	21890473
795	Ubiquitination	ERKRIFKDFMHVLEH HHHHHHHHHHHHHHH	35.04	33845483
797	Ubiquitination	KRIFKDFMHVLEHEC HHHHHHHHHHHHHHH	2.83	21890473
801	Phosphorylation	KDFMHVLEHECQHHH HHHHHHHHHHHHHHH	36.23	19651622
801	Ubiquitination	KDFMHVLEHECQHHH HHHHHHHHHHHHHHH	36.23	21890473
801 (in isoform 2)	Phosphorylation	-	36.23	-
805	Phosphorylation	HVLEHECQHHHSKNK HHHHHHHHHHHHCCH	35.64	19651622
805 (in isoform 2)	Phosphorylation	-	35.64	-
806	Ubiquitination	VLEHECQHHHSKNKK HHHHHHHHHHHCCHH	32.08	21890473
809	Phosphorylation	HECQHHHSKNKKHSK HHHHHHHHCCHHCCH	33.30	30108239
810	Ubiquitination	ECQHHHSKNKKHSKK HHHHHHHCCHHCCHH	69.31	21890473
813 (in isoform 2)	Ubiquitination	-	63.61	21890473
826	Phosphorylation	KKHHRKRSRSRSGSD HHHHHHHHHCCCCCC	37.33	26552605
828	Phosphorylation	HHRKRSRSRSGSDSD HHHHHHHCCCCCCCC	31.85	25137130
830	Phosphorylation	RKRSRSRSGSDSDDD HHHHHCCCCCCCCCC	43.85	25137130
830 (in isoform 2)	Phosphorylation	-	43.85	-
831	Phosphorylation	KRSRSRSGSDSDDDD HHHHCCCCCCCCCCC	34.07	19651622
831 (in isoform 2)	Phosphorylation	-	34.07	-
832	Phosphorylation	RSRSRSGSDSDDDDS HHHCCCCCCCCCCCC	34.88	25137130
834	Phosphorylation	RSRSGSDSDDDDSHS HCCCCCCCCCCCCHH	44.64	25137130
835	Phosphorylation	SRSGSDSDDDDSHSK CCCCCCCCCCCCHHH	69.24	19651622
835 (in isoform 2)	Phosphorylation	-	69.24	-
837	Phosphorylation	SGSDSDDDDSHSKKK CCCCCCCCCCHHHHH	65.39	33259812
837	Ubiquitination	SGSDSDDDDSHSKKK CCCCCCCCCCHHHHH	65.39	24816145
839	Phosphorylation	SDSDDDDSHSKKKRQ CCCCCCCCHHHHHHH	36.33	29262532
841	Phosphorylation	SDDDDSHSKKKRQRS CCCCCCHHHHHHHHH	50.55	26552605
841	Ubiquitination	SDDDDSHSKKKRQRS CCCCCCHHHHHHHHH	50.55	24816145
843	Ubiquitination	DDDSHSKKKRQRSES CCCCHHHHHHHHHHH	57.09	23503661
847	Ubiquitination	HSKKKRQRSESRSAS HHHHHHHHHHHHCHH	46.56	23503661
849	Phosphorylation	KKKRQRSESRSASEH HHHHHHHHHHCHHHH	52.97	33259812
852	Phosphorylation	RQRSESRSASEHSSS HHHHHHHCHHHHCCH	45.48	-
853	Phosphorylation	QRSESRSASEHSSSA HHHHHHCHHHHCCHH	20.16	33259812
854	Phosphorylation	RSESRSASEHSSSAE HHHHHCHHHHCCHHH	36.77	25849741
855	Ubiquitination	SESRSASEHSSSAES HHHHCHHHHCCHHHH	47.72	24816145
856	Phosphorylation	ESRSASEHSSSAESE HHHCHHHHCCHHHHH	30.41	17081983
856 (in isoform 2)	Phosphorylation	-	30.41	-
857	Phosphorylation	SRSASEHSSSAESER HHCHHHHCCHHHHHH	23.18	23909892
858	Phosphorylation	RSASEHSSSAESERS HCHHHHCCHHHHHHH	35.16	25849741
858 (in isoform 2)	Phosphorylation	-	35.16	24719451
859	Phosphorylation	SASEHSSSAESERSY CHHHHCCHHHHHHHH	38.79	23909892
859	Ubiquitination	SASEHSSSAESERSY CHHHHCCHHHHHHHH	38.79	24816145
861	Phosphorylation	SEHSSSAESERSYKK HHHCCHHHHHHHHHH	55.89	20068231
861	Ubiquitination	SEHSSSAESERSYKK HHHCCHHHHHHHHHH	55.89	23503661
861 (in isoform 2)	Phosphorylation	-	55.89	24719451
862	Phosphorylation	EHSSSAESERSYKKS HHCCHHHHHHHHHHH	37.72	25849741
865	Phosphorylation	SSAESERSYKKSKKH CHHHHHHHHHHHHHH	36.93	23909892
865	Ubiquitination	SSAESERSYKKSKKH CHHHHHHHHHHHHHH	36.93	23503661
866	Phosphorylation	SAESERSYKKSKKHK HHHHHHHHHHHHHHH	28.76	26657352
869	Phosphorylation	SERSYKKSKKHKKKS HHHHHHHHHHHHHHH	42.66	26657352
870	Acetylation	ERSYKKSKKHKKKSK HHHHHHHHHHHHHHH	68.71	90179
873	Acetylation	YKKSKKHKKKSKKRR HHHHHHHHHHHHHHH	71.43	90183
874	Acetylation	KKSKKHKKKSKKRRH HHHHHHHHHHHHHHC	63.10	90187
883	Phosphorylation	SKKRRHKSDSPESDA HHHHHCCCCCCCHHH	36.88	29255136
885	Phosphorylation	KRRHKSDSPESDAER HHHCCCCCCCHHHHH	37.34	29255136
887	Phosphorylation	RHKSDSPESDAEREK HCCCCCCCHHHHHHH	66.26	33259812
888	Phosphorylation	HKSDSPESDAEREKD CCCCCCCHHHHHHHH	45.57	29255136
891	Phosphorylation	DSPESDAEREKDKKE CCCCHHHHHHHHHHH	67.38	33259812
896	Phosphorylation	DAEREKDKKEKDRES HHHHHHHHHHHHHHH	74.11	20068231
896 (in isoform 2)	Phosphorylation	-	74.11	-
899	Ubiquitination	REKDKKEKDRESEKD HHHHHHHHHHHHHHH	71.60	23503661
900	Phosphorylation	EKDKKEKDRESEKDR HHHHHHHHHHHHHHH	61.75	17081983
900 (in isoform 2)	Phosphorylation	-	61.75	-
903	Ubiquitination	KKEKDRESEKDRTRQ HHHHHHHHHHHHHHH	51.33	23503661
905	Phosphorylation	EKDRESEKDRTRQRS HHHHHHHHHHHHHHH	62.89	18767875
905 (in isoform 2)	Phosphorylation	-	62.89	-
906	Phosphorylation	KDRESEKDRTRQRSE HHHHHHHHHHHHHHH	53.80	18767875
906 (in isoform 2)	Phosphorylation	-	53.80	27251275
908	Phosphorylation	RESEKDRTRQRSESK HHHHHHHHHHHHHHC	41.09	20068231
908 (in isoform 2)	Phosphorylation	-	41.09	27251275
909	Phosphorylation	ESEKDRTRQRSESKH HHHHHHHHHHHHHCC	30.70	33259812
911	Phosphorylation	EKDRTRQRSESKHKS HHHHHHHHHHHCCCC	38.82	18452278
911 (in isoform 2)	Phosphorylation	-	38.82	24719451
912	Phosphorylation	KDRTRQRSESKHKSP HHHHHHHHHHCCCCC	37.57	30576142
914	Phosphorylation	RTRQRSESKHKSPKK HHHHHHHHCCCCCCC	41.11	30576142
917	Ubiquitination	QRSESKHKSPKKKTG HHHHHCCCCCCCCCC	72.66	23503661
917 (in isoform 2)	Ubiquitination	-	72.66	-
918	Phosphorylation	RSESKHKSPKKKTGK HHHHCCCCCCCCCCC	41.49	24706070
921	Ubiquitination	SKHKSPKKKTGKDSG HCCCCCCCCCCCCCC	59.98	23503661
921 (in isoform 2)	Phosphorylation	-	59.98	24719451
923	Phosphorylation	HKSPKKKTGKDSGNW CCCCCCCCCCCCCCC	59.34	20068231
925	Acetylation	SPKKKTGKDSGNWDT CCCCCCCCCCCCCCC	54.69	23236377
927	Phosphorylation	KKKTGKDSGNWDTSG CCCCCCCCCCCCCCC	37.20	23927012
929	Phosphorylation	KTGKDSGNWDTSGSE CCCCCCCCCCCCCCC	37.08	33259812
932	Phosphorylation	KDSGNWDTSGSELSE CCCCCCCCCCCCCCH	26.97	20201521
933	Phosphorylation	DSGNWDTSGSELSEG CCCCCCCCCCCCCHH	37.54	20201521
935	Phosphorylation	GNWDTSGSELSEGEL CCCCCCCCCCCHHHH	34.82	20201521
938	Phosphorylation	DTSGSELSEGELEKR CCCCCCCCHHHHHHH	39.23	22167270
944	Ubiquitination	LSEGELEKRRRTLLE CCHHHHHHHHHHHHH	64.92	-
947	Phosphorylation	GELEKRRRTLLEQLD HHHHHHHHHHHHHHC	33.48	33259812
948	Phosphorylation	ELEKRRRTLLEQLDD HHHHHHHHHHHHHCC	33.61	21712546
951	Phosphorylation	KRRRTLLEQLDDDQ- HHHHHHHHHHCCCC-	52.81	33259812
1005	Ubiquitination	------------------------------------------------------- -------------------------------------------------------		23503661
1009	Ubiquitination	----------------------------------------------------------- -----------------------------------------------------------		23503661
1023	Ubiquitination	------------------------------------------------------------------------- -------------------------------------------------------------------------		23503661
1027	Ubiquitination	----------------------------------------------------------------------------- -----------------------------------------------------------------------------		23503661

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PR40A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PR40A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PR40A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HD_HUMAN	HTT	physical	9700202
TCAL9_HUMAN	WBP5	physical	9171351
FMNL3_HUMAN	FMNL3	physical	9171351
MECP2_HUMAN	MECP2	physical	9171351
ZFHX3_HUMAN	ZFHX3	physical	9171351
FMN1_HUMAN	FMN1	physical	11604498
LARP7_HUMAN	LARP7	physical	21900206
MLP3A_HUMAN	MAP1LC3A	physical	15383276
TCRG1_HUMAN	TCERG1	physical	22939629
SAP18_HUMAN	SAP18	physical	22939629
UT14A_HUMAN	UTP14A	physical	22939629
RRS1_HUMAN	RRS1	physical	22939629
TRA2A_HUMAN	TRA2A	physical	22939629
RL37A_HUMAN	RPL37A	physical	22939629
VTNC_HUMAN	VTN	physical	22939629
TR112_HUMAN	TRMT112	physical	22939629
RS9_HUMAN	RPS9	physical	22939629
PR40A_HUMAN	PRPF40A	physical	22365833
SF3A1_HUMAN	SF3A1	physical	22365833
SF3B2_HUMAN	SF3B2	physical	22365833
U2AF1_HUMAN	U2AF1	physical	22365833
SR140_HUMAN	U2SURP	physical	22365833
CHERP_HUMAN	CHERP	physical	22365833
RBM39_HUMAN	RBM39	physical	22365833
SNIP1_HUMAN	SNIP1	physical	22365833
RBMX2_HUMAN	RBMX2	physical	22365833
DHX8_HUMAN	DHX8	physical	22365833
PPIG_HUMAN	PPIG	physical	22365833
F10C1_HUMAN	FRA10AC1	physical	22365833
NKAP_HUMAN	NKAP	physical	22365833
ZCH10_HUMAN	ZCCHC10	physical	22365833
DIAP1_HUMAN	DIAPH1	physical	15231748
BRD4_HUMAN	BRD4	physical	15231748
PIAS1_HUMAN	PIAS1	physical	15231748
FMNL1_HUMAN	FMNL1	physical	15231748
RU17_HUMAN	SNRNP70	physical	15231748
PTPRF_HUMAN	PTPRF	physical	15231748
KAP0_HUMAN	PRKAR1A	physical	15231748
PECA1_HUMAN	PECAM1	physical	15231748
PFKAL_HUMAN	PFKL	physical	15231748
VINC_HUMAN	VCL	physical	15231748
SON_HUMAN	SON	physical	15231748
CAP2_HUMAN	CAP2	physical	15231748
BAG6_HUMAN	BAG6	physical	15231748
UBC9_HUMAN	UBE2I	physical	15231748
RLF_HUMAN	RLF	physical	15231748
CDK13_HUMAN	CDK13	physical	15231748
PSG5_HUMAN	PSG5	physical	15231748
PCBP2_HUMAN	PCBP2	physical	15231748
UBR4_HUMAN	UBR4	physical	15231748
ZCHC8_HUMAN	ZCCHC8	physical	15231748
ASXL2_HUMAN	ASXL2	physical	15231748
SDK1_HUMAN	SDK1	physical	15231748
HIPK1_HUMAN	HIPK1	physical	15231748
FMNL3_HUMAN	FMNL3	physical	15231748
FNBP4_HUMAN	FNBP4	physical	15231748
PDCD7_HUMAN	PDCD7	physical	15231748
FMNL2_HUMAN	FMNL2	physical	15231748
HNRL1_HUMAN	HNRNPUL1	physical	15231748
IL1AP_HUMAN	IL1RAP	physical	15231748
UBQL4_HUMAN	UBQLN4	physical	15231748
LTBP3_HUMAN	LTBP3	physical	15231748
CDK12_HUMAN	CDK12	physical	15231748
STIM2_HUMAN	STIM2	physical	15231748
UBQL2_HUMAN	UBQLN2	physical	15231748
UBQL1_HUMAN	UBQLN1	physical	15231748
DAAM1_HUMAN	DAAM1	physical	15231748
ZN451_HUMAN	ZNF451	physical	15231748
BIG2_HUMAN	ARFGEF2	physical	15231748
PIAS3_HUMAN	PIAS3	physical	15231748
CDK12_HUMAN	CDK12	physical	16055720
YBOX1_HUMAN	YBX1	physical	16055720
DDX46_HUMAN	DDX46	physical	16055720
DHX15_HUMAN	DHX15	physical	16055720
HNRPF_HUMAN	HNRNPF	physical	16055720
NONO_HUMAN	NONO	physical	16055720
SF01_HUMAN	SF1	physical	16055720
SF3A1_HUMAN	SF3A1	physical	16055720
SF3A2_HUMAN	SF3A2	physical	16055720
SF3A3_HUMAN	SF3A3	physical	16055720
SF3B1_HUMAN	SF3B1	physical	16055720
SF3B2_HUMAN	SF3B2	physical	16055720
SF3B3_HUMAN	SF3B3	physical	16055720
SF3B4_HUMAN	SF3B4	physical	16055720
SFPQ_HUMAN	SFPQ	physical	16055720
U2AF2_HUMAN	U2AF2	physical	16055720
RL4_HUMAN	RPL4	physical	16055720
DIAP1_HUMAN	DIAPH1	physical	16055720
EVL_HUMAN	EVL	physical	16055720
FMNL1_HUMAN	FMNL1	physical	16055720
ABI1_HUMAN	ABI1	physical	16055720
VASP_HUMAN	VASP	physical	16055720
WASP_HUMAN	WAS	physical	16055720
WASL_HUMAN	WASL	physical	16055720
WIPF1_HUMAN	WIPF1	physical	16055720
ATD3A_HUMAN	ATAD3A	physical	16055720
NCKPL_HUMAN	NCKAP1L	physical	16055720
CPSF6_HUMAN	CPSF6	physical	16055720
DHX9_HUMAN	DHX9	physical	16055720
HNRPK_HUMAN	HNRNPK	physical	16055720
HNRPU_HUMAN	HNRNPU	physical	16055720
RLA0_HUMAN	RPLP0	physical	16055720
XRCC6_HUMAN	XRCC6	physical	16055720
RCC2_HUMAN	RCC2	physical	16055720
CYFP1_HUMAN	CYFIP1	physical	16055720
CYFP2_HUMAN	CYFIP2	physical	16055720
WASF2_HUMAN	WASF2	physical	16055720
AB1IP_HUMAN	APBB1IP	physical	16055720
YLPM1_HUMAN	YLPM1	physical	16055720
G3P_HUMAN	GAPDH	physical	16055720
TCPB_HUMAN	CCT2	physical	16055720
TCPD_HUMAN	CCT4	physical	16055720
TCPH_HUMAN	CCT7	physical	16055720
TE2IP_HUMAN	TERF2IP	physical	26186194
NKAP_HUMAN	NKAP	physical	26186194
NCBP3_HUMAN	C17orf85	physical	26186194
DDX46_HUMAN	DDX46	physical	26186194
CCDC9_HUMAN	CCDC9	physical	26186194
RNPS1_HUMAN	RNPS1	physical	26186194
TERF2_HUMAN	TERF2	physical	26186194
JMJD6_HUMAN	JMJD6	physical	26186194
CSK22_HUMAN	CSNK2A2	physical	26186194
ACINU_HUMAN	ACIN1	physical	26186194
PININ_HUMAN	PNN	physical	26186194
CSK21_HUMAN	CSNK2A1	physical	26186194
NPM3_HUMAN	NPM3	physical	26344197
RNPS1_HUMAN	RNPS1	physical	26344197
SF01_HUMAN	SF1	physical	15456888
U2AF2_HUMAN	U2AF2	physical	15456888
JMJD6_HUMAN	JMJD6	physical	28514442
ZCH18_HUMAN	ZC3H18	physical	28514442
TERF2_HUMAN	TERF2	physical	28514442
CCDC9_HUMAN	CCDC9	physical	28514442
NCBP3_HUMAN	C17orf85	physical	28514442
NKAP_HUMAN	NKAP	physical	28514442
PININ_HUMAN	PNN	physical	28514442
CSK22_HUMAN	CSNK2A2	physical	28514442
CSK21_HUMAN	CSNK2A1	physical	28514442
TE2IP_HUMAN	TERF2IP	physical	28514442
ACINU_HUMAN	ACIN1	physical	28514442
DDX46_HUMAN	DDX46	physical	28514442
RNPS1_HUMAN	RNPS1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;
Science 325:834-840(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-196 AND LYS-680, AND MASSSPECTROMETRY.
PubMed: 19608861

Phosphorylation

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-883; SER-885; SER-888;THR-932; SER-933; SER-935 AND SER-938, AND MASS SPECTROMETRY.
PubMed: 18669648

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-34, AND MASSSPECTROMETRY.
PubMed: 18220336

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-373; SER-883; SER-885;SER-888; THR-932; SER-933; SER-935 AND SER-938, AND MASS SPECTROMETRY.
PubMed: 17081983

"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-888 AND SER-938, ANDMASS SPECTROMETRY.
PubMed: 15302935

"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-932, AND MASSSPECTROMETRY.
PubMed: 18187866