dbPTM

YLPM1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YLPM1_HUMAN
UniProt AC	P49750
Protein Name	YLP motif-containing protein 1
Gene Name	YLPM1
Organism	Homo sapiens (Human).
Sequence Length	2146
Subcellular Localization	Nucleus . Nucleus speckle. Migrates to nucleolar caps upon blockage of transcription.
Protein Description	Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation..
Protein Sequence	MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQSTFPSKTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGLPRPDNRDNRLEGNRGNSSSYRGPGQSRMEDTRDKGLVNRGRGQAISRGPGLVKQEDFRDKMMGRREDSREKMNRGEGSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERGPPRGPGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAPSLSHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYEYEAEMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEINKMADHWETAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEEQKEEKKDAEEEESELGYIPKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYDTRASEPGKKRVRWADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAEKALNRTKYI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Methylation	-MYPNWGRYGGSSHY -CCCCCCCCCCCCCC	20.66	115385737
52	Phosphorylation	PSSSGFMSFREQHLA CCCCCCHHHHHHHHH	20.91	24719451
190	Phosphorylation	YLPPAQPSPSQSPPS CCCCCCCCCCCCCCC	25.71	26074081
192	Phosphorylation	PPAQPSPSQSPPSQS CCCCCCCCCCCCCCC	47.86	26074081
194	Phosphorylation	AQPSPSQSPPSQSYL CCCCCCCCCCCCCCC	43.02	26074081
197	Phosphorylation	SPSQSPPSQSYLAPT CCCCCCCCCCCCCCC	34.83	26074081
206	O-linked_Glycosylation	SYLAPTPSYSSSSSS CCCCCCCCCCCCCCC	39.87	30059200
227	O-linked_Glycosylation	HSQSYLPSSQASPSR HCCCCCCCCCCCCCC	32.27	30059200
227	Phosphorylation	HSQSYLPSSQASPSR HCCCCCCCCCCCCCC	32.27	26074081
228	O-linked_Glycosylation	SQSYLPSSQASPSRP CCCCCCCCCCCCCCC	28.03	30059200
231	Phosphorylation	YLPSSQASPSRPSQG CCCCCCCCCCCCCCC	18.77	26074081
231	O-linked_Glycosylation	YLPSSQASPSRPSQG CCCCCCCCCCCCCCC	18.77	30059200
233	Phosphorylation	PSSQASPSRPSQGHS CCCCCCCCCCCCCCC	55.09	26074081
236	O-linked_Glycosylation	QASPSRPSQGHSKSQ CCCCCCCCCCCCCHH	47.92	30059200
236	Phosphorylation	QASPSRPSQGHSKSQ CCCCCCCCCCCCCHH	47.92	26074081
242	Phosphorylation	PSQGHSKSQLLAPPP CCCCCCCHHCCCCCC	29.13	28555341
251	Phosphorylation	LLAPPPPSAPPGNKT CCCCCCCCCCCCCCC	60.21	28555341
258	Phosphorylation	SAPPGNKTTVQQEPL CCCCCCCCCCCCCCC	35.88	21406692
259	Phosphorylation	APPGNKTTVQQEPLE CCCCCCCCCCCCCCC	20.23	21406692
267	Phosphorylation	VQQEPLESGAKNKST CCCCCCCCCCCCCCH	52.30	21406692
270	Acetylation	EPLESGAKNKSTEQQ CCCCCCCCCCCHHHH	69.32	25953088
272 (in isoform 4)	Ubiquitination	-	59.03	-
289	Phosphorylation	EPDPSTMTPQEQQQY CCCCCCCCHHHHHHH	23.16	28555341
317	Acetylation	KVHLPGHKKGPVVAK CCCCCCCCCCCEECC	66.40	25953088
318	Acetylation	VHLPGHKKGPVVAKD CCCCCCCCCCEECCC	63.87	12431333
324	Acetylation	KKGPVVAKDTPEPVK CCCCEECCCCCCCCC	50.99	23954790
326	Phosphorylation	GPVVAKDTPEPVKEE CCEECCCCCCCCCEE	28.92	22199227
335	Phosphorylation	EPVKEEVTVPATSQV CCCCEECEECCCCCC	24.85	20068231
339	Phosphorylation	EEVTVPATSQVPESP EECEECCCCCCCCCC	17.39	20068231
340	Phosphorylation	EVTVPATSQVPESPS ECEECCCCCCCCCCC	31.14	20068231
345	Phosphorylation	ATSQVPESPSSEEPP CCCCCCCCCCCCCCC	24.82	28348404
347	Phosphorylation	SQVPESPSSEEPPLP CCCCCCCCCCCCCCC	60.71	28348404
348	Phosphorylation	QVPESPSSEEPPLPP CCCCCCCCCCCCCCC	49.73	29496963
371	Phosphorylation	LPPEEPQSEDPEEDA CCCCCCCCCCHHHHH	55.47	20068231
465	Phosphorylation	EFQLWEEQLHSYPHK HHHHHHHHHHHCCCH	27.79	20058876
478	Phosphorylation	HKDQLQEYEKQWKTW CHHHHHHHHHHHHHH	35.97	26853621
481	Phosphorylation	QLQEYEKQWKTWQGH HHHHHHHHHHHHHHH	25.70	23186163
490 (in isoform 4)	Ubiquitination	-	18.14	-
518	Phosphorylation	MGNMSMPPPFVPYSQ CCCCCCCCCCCCHHH	24.25	27251275
520	Phosphorylation	NMSMPPPFVPYSQMP CCCCCCCCCCHHHCC	34.65	28348404
521	Phosphorylation	MSMPPPFVPYSQMPP CCCCCCCCCHHHCCC	31.76	27251275
528	Phosphorylation	VPYSQMPPPLPTMPP CCHHHCCCCCCCCCC	24.39	25159151
529	Phosphorylation	PYSQMPPPLPTMPPP CHHHCCCCCCCCCCC	24.93	25159151
540	Methylation	MPPPVLPPSLPPPVM CCCCCCCCCCCCCCC	45.93	24129315
540	Acetylation	MPPPVLPPSLPPPVM CCCCCCCCCCCCCCC	45.93	26051181
546	Phosphorylation	PPSLPPPVMPPALPA CCCCCCCCCCCCCCC	37.13	28555341
555	Methylation	PPALPATVPPPGMPP CCCCCCCCCCCCCCC	43.56	-
556 (in isoform 1)	O-linked_Glycosylation	-	29.16	30059200
556	Phosphorylation	PALPATVPPPGMPPP CCCCCCCCCCCCCCC	29.16	27251275
557	Phosphorylation	ALPATVPPPGMPPPV CCCCCCCCCCCCCCC	34.71	29396449
558	Phosphorylation	LPATVPPPGMPPPVM CCCCCCCCCCCCCCC	18.74	30266825
561	Phosphorylation	TVPPPGMPPPVMPPS CCCCCCCCCCCCCCC	19.80	30266825
563	Dimethylation	PPPGMPPPVMPPSLP CCCCCCCCCCCCCCC	76.62	-
563	Methylation	PPPGMPPPVMPPSLP CCCCCCCCCCCCCCC	76.62	-
566	Dimethylation	GMPPPVMPPSLPTSV CCCCCCCCCCCCCCC	45.15	-
566	Methylation	GMPPPVMPPSLPTSV CCCCCCCCCCCCCCC	45.15	-
571	Methylation	VMPPSLPTSVPPPGM CCCCCCCCCCCCCCC	62.54	-
572	Methylation	MPPSLPTSVPPPGMP CCCCCCCCCCCCCCC	42.30	-
579	Methylation	SVPPPGMPPSLSSAG CCCCCCCCCCHHHCC	22.25	-
584	Methylation	GMPPSLSSAGPPPVL CCCCCHHHCCCCCCC	57.32	-
586	Methylation	PPSLSSAGPPPVLPP CCCHHHCCCCCCCCC	80.82	-
589	Dimethylation	LSSAGPPPVLPPPSL HHHCCCCCCCCCCCH	51.41	-
589	Methylation	LSSAGPPPVLPPPSL HHHCCCCCCCCCCCH	51.41	-
594	Dimethylation	PPPVLPPPSLSSAGP CCCCCCCCCHHCCCC	41.36	-
594	Methylation	PPPVLPPPSLSSAGP CCCCCCCCCHHCCCC	41.36	-
599	Dimethylation	PPPSLSSAGPPPVLP CCCCHHCCCCCCCCC	33.58	-
599	Methylation	PPPSLSSAGPPPVLP CCCCHHCCCCCCCCC	33.58	-
601	Dimethylation	PSLSSAGPPPVLPPP CCHHCCCCCCCCCCC	43.33	-
601	Methylation	PSLSSAGPPPVLPPP CCHHCCCCCCCCCCC	43.33	-
602	Phosphorylation	SLSSAGPPPVLPPPS CHHCCCCCCCCCCCC	29.01	25367160
613	Methylation	PPPSLSSTAPPPVMP CCCCCCCCCCCCCCC	49.69	24129315
613	Acetylation	PPPSLSSTAPPPVMP CCCCCCCCCCCCCCC	49.69	25953088
619	Dimethylation	STAPPPVMPLPPLSS CCCCCCCCCCCCCCC	53.45	-
619	Methylation	STAPPPVMPLPPLSS CCCCCCCCCCCCCCC	53.45	24129315
623	Phosphorylation	PPVMPLPPLSSATPP CCCCCCCCCCCCCCC	24.77	23403867
626	Phosphorylation	MPLPPLSSATPPPGI CCCCCCCCCCCCCCC	9.03	28102081
626 (in isoform 4)	Phosphorylation	-	9.03	17360941
628	Phosphorylation	LPPLSSATPPPGIPP CCCCCCCCCCCCCCC	10.37	30266825
630	Phosphorylation	PLSSATPPPGIPPPG CCCCCCCCCCCCCCC	23.21	30266825
631	Phosphorylation	LSSATPPPGIPPPGV CCCCCCCCCCCCCCC	34.59	30266825
632	Phosphorylation	SSATPPPGIPPPGVP CCCCCCCCCCCCCCC	31.05	30266825
634	Phosphorylation	ATPPPGIPPPGVPQG CCCCCCCCCCCCCCC	20.15	25159151
636	Dimethylation	PPPGIPPPGVPQGIP CCCCCCCCCCCCCCC	39.66	-
636	Methylation	PPPGIPPPGVPQGIP CCCCCCCCCCCCCCC	39.66	24129315
643	Methylation	PGVPQGIPPQLTAAP CCCCCCCCCCCCCCC	61.15	-
646	Acetylation	PQGIPPQLTAAPVPP CCCCCCCCCCCCCCC	58.61	26051181
659	Phosphorylation	PPASSSQSSQVPEKP CCCCCCCCCCCCCCC	41.11	23186163
660	Phosphorylation	PASSSQSSQVPEKPR CCCCCCCCCCCCCCC	56.74	20058876
665	Phosphorylation	QSSQVPEKPRPALLP CCCCCCCCCCCCCCC	51.54	25159151
668	Acetylation	QVPEKPRPALLPTPV CCCCCCCCCCCCCCC	65.32	26051181
674	Phosphorylation	RPALLPTPVSFGSAP CCCCCCCCCCCCCCC	28.57	28555341
675	Phosphorylation	PALLPTPVSFGSAPP CCCCCCCCCCCCCCC	28.04	21712546
676	Phosphorylation	ALLPTPVSFGSAPPT CCCCCCCCCCCCCCC	40.53	23186163
676	O-linked_Glycosylation	ALLPTPVSFGSAPPT CCCCCCCCCCCCCCC	40.53	30059200
680	Acetylation	TPVSFGSAPPTTYHP CCCCCCCCCCCCCCC	55.37	26051181
684	O-linked_Glycosylation	FGSAPPTTYHPPLQS CCCCCCCCCCCCCHH	3.13	30059200
690	Phosphorylation	TTYHPPLQSAGPSEQ CCCCCCCHHCCCCHH	13.44	28555341
696	Acetylation	LQSAGPSEQVNSKAP CHHCCCCHHCCCCCC	58.30	26051181
703	Phosphorylation	EQVNSKAPLSKSALP HHCCCCCCCCCCCCC	41.19	30243723
708	Phosphorylation	KAPLSKSALPYSSFS CCCCCCCCCCCCCCC	46.96	25627689
710	Phosphorylation	PLSKSALPYSSFSSD CCCCCCCCCCCCCCC	30.32	21815630
735	Methylation	SQPITAVKDMPVRSG CCCCEEEECCCCCCC	17.82	24129315
755	Acetylation	PPRSSYLESPRGPRF CCCHHHCCCCCCCCC	41.61	26051181
756	Phosphorylation	PRSSYLESPRGPRFD CCHHHCCCCCCCCCC	36.81	19664995
762	Phosphorylation	ESPRGPRFDGPRRFE CCCCCCCCCCCCCHH	27.73	23898821
780	Phosphorylation	SRCEGPRPKGPRFEG HCCCCCCCCCCCCCC	25.94	28555341
814	Methylation	SKWGMIPRGPASQFY CCCCCCCCCCHHHEE	38.10	24129315
819	Methylation	IPRGPASQFYITPST CCCCCHHHEEECCCC	57.43	-
822	Phosphorylation	GPASQFYITPSTSLS CCHHHEEECCCCCCC	24.40	26434776
823	Phosphorylation	PASQFYITPSTSLSP CHHHEEECCCCCCCC	35.07	26434776
824	Phosphorylation	ASQFYITPSTSLSPR HHHEEECCCCCCCCC	20.76	26434776
825	Phosphorylation	SQFYITPSTSLSPRQ HHEEECCCCCCCCCC	22.87	26434776
827	Phosphorylation	FYITPSTSLSPRQSG EEECCCCCCCCCCCC	23.58	20058876
829	Phosphorylation	ITPSTSLSPRQSGPQ ECCCCCCCCCCCCCC	40.70	19664995
831	Phosphorylation	PSTSLSPRQSGPQWK CCCCCCCCCCCCCCC	39.24	22798277
831	Methylation	PSTSLSPRQSGPQWK CCCCCCCCCCCCCCC	39.24	24129315
839	Acetylation	QSGPQWKGPKPAFGQ CCCCCCCCCCCCCCH	51.35	25953088
846	Dimethylation	GPKPAFGQQHQQQPK CCCCCCCHHHCCCCH	30.71	-
846	Methylation	GPKPAFGQQHQQQPK CCCCCCCHHHCCCCH	30.71	-
858	Methylation	QPKSQAEPLSGNKEP CCHHHCCCCCCCCCC	53.68	-
858	Sumoylation	QPKSQAEPLSGNKEP CCHHHCCCCCCCCCC	53.68	-
858	Sumoylation	QPKSQAEPLSGNKEP CCHHHCCCCCCCCCC	53.68	-
886	Methylation	MQSAAFSIAADVKDV HHHHHHHHHHHHHHH	38.95	-
890	Methylation	AFSIAADVKDVKAAQ HHHHHHHHHHHHHHH	34.60	-
891	Sumoylation	FSIAADVKDVKAAQS HHHHHHHHHHHHHHC	39.27	28112733
893	Phosphorylation	IAADVKDVKAAQSNE HHHHHHHHHHHHCCC	28.98	23401153
894	Phosphorylation	AADVKDVKAAQSNEN HHHHHHHHHHHCCCC	50.83	30266825
905	Phosphorylation	SNENLSDSQQEPPKS CCCCCCCCCCCCCCC	18.88	30266825
908	Methylation	NLSDSQQEPPKSEVS CCCCCCCCCCCCCCC	29.07	-
913	Phosphorylation	QQEPPKSEVSEGPVE CCCCCCCCCCCCCCC	26.66	23663014
924	Phosphorylation	GPVEPSNWDQNVQSM CCCCCCCHHHHHHHH	28.08	23401153
935	Phosphorylation	VQSMETQIDKAQAVT HHHHHHHHHHHHHHC	29.95	29414761
946	Phosphorylation	QAVTQPVPLANKPVP HHHCCCCCCCCCCCC	29.95	23312004
949	Methylation	TQPVPLANKPVPAQS CCCCCCCCCCCCCCC	62.90	-
953	Methylation	PLANKPVPAQSTFPS CCCCCCCCCCCCCCC	68.05	-
957	Phosphorylation	KPVPAQSTFPSKTGG CCCCCCCCCCCCCCC	33.82	23403867
958	Methylation	PVPAQSTFPSKTGGM CCCCCCCCCCCCCCC	43.47	-
960	Methylation	PAQSTFPSKTGGMEG CCCCCCCCCCCCCCC	44.52	-
964	Methylation	TFPSKTGGMEGGTAV CCCCCCCCCCCCEEE	37.79	-
965	Phosphorylation	FPSKTGGMEGGTAVA CCCCCCCCCCCEEEE	35.18	28555341
983	Sumoylation	LTADNDFKPVGIGLP CCCCCCCCCCCCCCC	39.93	25114211
1043	Phosphorylation	LVNRGRGQAISRGPG CCCCCCCCCCCCCCC	30.35	30108239
1047	Phosphorylation	GRGQAISRGPGLVKQ CCCCCCCCCCCCCCH	11.64	30108239
1053	Sumoylation	SRGPGLVKQEDFRDK CCCCCCCCHHHHHHH	12.97	25114211
1054	Phosphorylation	RGPGLVKQEDFRDKM CCCCCCCHHHHHHHH	40.54	30266825
1058	Phosphorylation	LVKQEDFRDKMMGRR CCCHHHHHHHHCCCC	45.41	23403867
1060	Phosphorylation	KQEDFRDKMMGRRED CHHHHHHHHCCCCHH	30.21	23403867
1099	Phosphorylation	KVPGGLQGSQDRGAA CCCCCCCCCCCCCCC	31.09	29449344
1100	Phosphorylation	VPGGLQGSQDRGAAG CCCCCCCCCCCCCCC	28.35	23186163
1105	Phosphorylation	QGSQDRGAAGSRERG CCCCCCCCCCCCCCC	12.16	-
1108	Phosphorylation	QDRGAAGSRERGPPR CCCCCCCCCCCCCCC	36.86	23663014
1117	Phosphorylation	ERGPPRRAGSQERGP CCCCCCCCCCCCCCC	18.87	-
1119	Phosphorylation	GPPRRAGSQERGPLR CCCCCCCCCCCCCCC	23.52	17081983
1135	Phosphorylation	AGSRERIPPRRAGSR CCCCCCCCCCCCCCC	54.57	28348404
1181	Phosphorylation	GDGGEKMYPYHRDEP CCCCCCCCCCCCCCC	10.67	22210691
1187	Phosphorylation	MYPYHRDEPPRAPWN CCCCCCCCCCCCCCC	29.28	22210691
1198	Methylation	APWNHGEERGHEEFP CCCCCCCCCCCCCCC	20.91	-
1207	Phosphorylation	GHEEFPLDGRNAPME CCCCCCCCCCCCCCH	31.20	28112733
1211	Phosphorylation	FPLDGRNAPMERERL CCCCCCCCCCHHHHC	8.18	26074081
1213	Phosphorylation	LDGRNAPMERERLDD CCCCCCCCHHHHCCH	34.27	26074081
1219	Phosphorylation	PMERERLDDWDRERY CCHHHHCCHHHHHHH	19.77	26074081
1227	Phosphorylation	DWDRERYWRECERDY HHHHHHHHHHHHHHH	34.43	27794612
1228	Phosphorylation	WDRERYWRECERDYQ HHHHHHHHHHHHHHC	21.24	27794612
1231	Phosphorylation	ERYWRECERDYQDDT HHHHHHHHHHHCCCH	23.67	27794612
1232	Phosphorylation	RYWRECERDYQDDTL HHHHHHHHHHCCCHH	25.75	27794612
1237	Phosphorylation	CERDYQDDTLELYNR HHHHHCCCHHHHHCC	16.47	26074081
1240	Phosphorylation	DYQDDTLELYNREDR HHCCCHHHHHCCCCC	37.39	26074081
1243	Phosphorylation	DDTLELYNREDRFSA CCHHHHHCCCCCCCC	36.81	26074081
1254	Phosphorylation	RFSAPPSRSHDGDRR CCCCCCCCCCCCCCC	16.35	26074081
1263	Methylation	HDGDRRGPWWDDWER CCCCCCCCCCCCCHH	31.13	-
1305	Phosphorylation	DMYDRSLDNEWDRDY HHCCCCCCCCCHHCC	31.72	20068231
1318	Methylation	DYGRPLDEQESQFRE CCCCCCCHHHHHHHH	38.66	-
1329	Phosphorylation	QFRERDIPSLPPLPP HHHHCCCCCCCCCCC	24.55	28634298
1332	Methylation	ERDIPSLPPLPPLPP HCCCCCCCCCCCCCC	20.13	-
1334	Phosphorylation	DIPSLPPLPPLPPLP CCCCCCCCCCCCCCC	42.73	28634298
1339	Methylation	PPLPPLPPLPPLDRY CCCCCCCCCCCHHHC	34.93	-
1346	Dimethylation	PLPPLDRYRDDRWRE CCCCHHHCCCHHHHH	33.49	-
1346	Methylation	PLPPLDRYRDDRWRE CCCCHHHCCCHHHHH	33.49	-
1385	Phosphorylation	ERGDTWREKRDYVPD CCCCCHHHHCCCCCC	18.43	-
1402	Phosphorylation	DWERERLSDRWYPSD HHHHHHHHCCCCCCC	45.56	23186163
1454	Phosphorylation	VLSQRQHEIILKAAQ EECHHHHHHHHHHHH	30.16	28555341
1455	Phosphorylation	LSQRQHEIILKAAQE ECHHHHHHHHHHHHH	39.12	28555341
1457	Acetylation	QRQHEIILKAAQELK HHHHHHHHHHHHHHH	47.43	26051181
1463	Phosphorylation	ILKAAQELKMLREQK HHHHHHHHHHHHHHH	32.99	20068231
1495	Methylation	HLPPQESRLQNTSSR CCCCCHHHCCCCCCC	49.53	115385721
1500	Phosphorylation	ESRLQNTSSRPGMYP HHHCCCCCCCCCCCC	17.23	20068231
1503	Methylation	LQNTSSRPGMYPPPG CCCCCCCCCCCCCCC	31.74	-
1505	Phosphorylation	NTSSRPGMYPPPGSY CCCCCCCCCCCCCCC	33.68	29214152
1533	Phosphorylation	VRPSAPPARSSVPVT CCCCCCCCCCCCCCC	11.18	23403867
1562	Methylation	LPPPPPVIKPQTSAV CCCCCCCCCCCCCCC	43.12	-
1563	Dimethylation	PPPPPVIKPQTSAVE CCCCCCCCCCCCCCC	52.08	-
1563	Methylation	PPPPPVIKPQTSAVE CCCCCCCCCCCCCCC	52.08	-
1575	Phosphorylation	AVEQERWDEDSFYGL CCCCCCCCCCCCCCC	39.48	21945579
1580	Phosphorylation	RWDEDSFYGLWDTND CCCCCCCCCCCCCCC	20.18	21945579
1597	Methylation	GLNSEFKSETAAIPS CCCHHHCCCCCCCCC	30.29	-
1604	Phosphorylation	SETAAIPSAPVLPPP CCCCCCCCCCCCCCC	44.61	28555341
1606	Phosphorylation	TAAIPSAPVLPPPPV CCCCCCCCCCCCCCC	25.14	28555341
1618	Acetylation	PPVHSSIPPPGPVPM CCCCCCCCCCCCCCC	40.28	-
1629	Acetylation	PVPMGMPPMSKPPPV CCCCCCCCCCCCCCC	49.88	-
1652	Sumoylation	GRDISTNKVEQIPYG CCCCCCCCEEECCCC	36.84	28112733
1675	Phosphorylation	PLPERSTFETEHAGQ CCCCCCCCCCCCCCC	27.22	20736484
1679	Phosphorylation	RSTFETEHAGQRDRY CCCCCCCCCCCCCCC	9.13	-
1682	Phosphorylation	FETEHAGQRDRYDRE CCCCCCCCCCCCHHH	24.87	-
1695	Acetylation	RERDREPYFDRQSNV HHHCCCCCCCHHCCC	59.34	26051181
1695	Phosphorylation	RERDREPYFDRQSNV HHHCCCCCCCHHCCC	59.34	20068231
1696	Acetylation	ERDREPYFDRQSNVI HHCCCCCCCHHCCCC	63.91	-
1698	Acetylation	DREPYFDRQSNVIAD CCCCCCCHHCCCCCC	56.61	-
1699	Acetylation	REPYFDRQSNVIADH CCCCCCHHCCCCCCC	54.29	-
1700	Acetylation	EPYFDRQSNVIADHR CCCCCHHCCCCCCCC	40.89	-
1710	Sumoylation	IADHRDFKRDRETHR CCCCCHHHHHHHHHH	7.90	28112733
1720	Acetylation	RETHRDRDRDRGVID HHHHHHHHCCCCCCC	44.39	25953088
1728	Phosphorylation	RDRGVIDYDRDRFDR CCCCCCCCCCCCCCC	59.93	18452278
1771	Phosphorylation	PSYDRKSDRPVYEGP CCCCCCCCCCCCCCC	29.49	-
1787	Acetylation	MFGGERRTYPEERMP CCCCCCCCCCCHHCC	40.92	25953088
1840	Phosphorylation	ERIVVIMRGLPGSGK CEEEEEEECCCCCCH	41.21	30266825
1844	Phosphorylation	VIMRGLPGSGKTHVA EEEECCCCCCHHHHH	27.03	-
1849	Acetylation	LPGSGKTHVAKLIRD CCCCCHHHHHHHHHC	53.98	25953088
1857 (in isoform 4)	Ubiquitination	-	19.92	-
1857	2-Hydroxyisobutyrylation	VAKLIRDKEVEFGGP HHHHHHCCCCCCCCC	19.92	-
1861	Acetylation	IRDKEVEFGGPAPRV HHCCCCCCCCCCCCE	59.94	23236377
1885	Phosphorylation	EVEKEEKDPDSGKKV EHHHHHCCCCCCHHH	5.30	28796482
1892	Phosphorylation	DPDSGKKVKKKVMEY CCCCCHHHHHHHHHH	26.96	-
1894	Phosphorylation	DSGKKVKKKVMEYEY CCCHHHHHHHHHHHH	23.16	28555341
1897 (in isoform 1)	O-linked_Glycosylation	-	40.82	30059200
1897	Phosphorylation	KKVKKKVMEYEYEAE HHHHHHHHHHHHHHH	40.82	24114839
1928	Phosphorylation	LDDGFFPFIILDAIN HCCCCCCCHHHHHHH	36.83	-
1943	Acetylation	DRVRHFDQFWSAAKT HHHHHHHHHHHHHHH	53.20	23749302

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YLPM1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YLPM1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YLPM1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ANM1_HUMAN	PRMT1	physical	16169070
SCG1_HUMAN	CHGB	physical	16169070
SMRC1_HUMAN	SMARCC1	physical	26344197
SMRC2_HUMAN	SMARCC2	physical	26344197

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YLPM1_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-634, AND MASSSPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-634, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-634, AND MASSSPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-634, AND MASSSPECTROMETRY.	18220336 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-924, AND MASSSPECTROMETRY.	17081983 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-634, AND MASSSPECTROMETRY.	15302935 [Abstract]