PDCD7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PDCD7_HUMAN
• UniProt AC: Q8N8D1
• Protein Name: Programmed cell death protein 7
• Gene Name: PDCD7
• Organism: Homo sapiens (Human).
• Sequence Length: 485
• Subcellular Localization: Nucleus .
• Protein Description: Promotes apoptosis when overexpressed..
• Protein Sequence: MALPPFFGQGRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGGGGAGAFYPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQRLRDRQWLEAVFGTPRRAGCPVPQRTHAGPSLGEVRARLLRALRLVRRLRGLSQALREAEADGAAWVLLYSQTAPLRAELAERLQPLTQAAYVGEARRRLERVRRRRLRLRERAREREAEREAEAARAVEREQEIDRWRVKCVQEVEEKKREQELKAAADGVLSEVRKKQADTKRMVDILRALEKLRKLRKEAAARKGVCPPASADETFTHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERKRELEKKQRKEKEKILLQKREIESKLFGDPDEFPLAHLLEPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNFVPQGWVLPPLPSNDIWATAVKLH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
119	Phosphorylation	PGPGPPWSPRWPEAP CCCCCCCCCCCCCCC	15.45	24719451
153	Phosphorylation	WLEAVFGTPRRAGCP HHHHHHCCCCCCCCC	11.36	21815630
170	Phosphorylation	QRTHAGPSLGEVRAR CCCCCCCCHHHHHHH	48.35	-
280	Ubiquitination	EIDRWRVKCVQEVEE HHHHHHHHHHHHHHH	21.80	-
295	Ubiquitination	KKREQELKAAADGVL HHHHHHHHHHHHHHH	34.92	-
312	Phosphorylation	VRKKQADTKRMVDIL HHHHHCCHHHHHHHH	24.46	-
336	Ubiquitination	RKEAAARKGVCPPAS HHHHHHHCCCCCCCC	51.47	-
361	Ubiquitination	RLRKLIKKRSELYEA HHHHHHHHHHHHHHH	54.91	-
376	Sulfoxidation	EERALRVMLEGEQEE HHHHHHHHHHCCHHH	1.97	21406390
399	Ubiquitination	KQRKEKEKILLQKRE HHHHHHHHHHHHHHH	50.12	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PDCD7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PDCD7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PDCD7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FEZ1_HUMAN	FEZ1	physical	16169070
HAP1_HUMAN	HAP1	physical	16169070
A4_HUMAN	APP	physical	21832049
U520_HUMAN	SNRNP200	physical	22939629

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.