LRC15_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LRC15_HUMAN
• UniProt AC: Q8TF66
• Protein Name: Leucine-rich repeat-containing protein 15
• Gene Name: LRRC15
• Organism: Homo sapiens (Human).
• Sequence Length: 581
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Sequence: MPLKHYLLLLVGCQAWGAGLAYHGCPSECTCSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPANVRGQSLIIINVNVAVPSVHVPEVPSYPETPWYPDTPSYPDTTSVSSTTELTSPVEDYTDLTTIQVTDDRSVWGMTQAQSGLAIAAIVIGIVALACSLAACVGCCCCKKRSQAVLMQMKAPNEC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
39	S-palmitoylation	SRASQVECTGARIVA CCCCCEEECCCEEEE	4.46	29575903
75	N-linked_Glycosylation	LNESPFLNISALIAL CCCCCCCCHHHHHHH	26.92	UniProtKB CARBOHYD
102	Phosphorylation	GAFRNLGSLRYLSLA CHHCHHCHHHHHHHC	16.91	24719451
189	Phosphorylation	KNSLTHISPRVFQHL CCCCCCCCHHHHHHH	10.07	28348404
369	N-linked_Glycosylation	RMLANLQNISLQNNR HHHHHHHHHHCCCCH	29.05	UniProtKB CARBOHYD
371	Phosphorylation	LANLQNISLQNNRLR HHHHHHHHCCCCHHH	31.30	20068231
453	S-palmitoylation	GTDTVPVCFSPANVR CCCCCCEEECCCCCC	1.98	29575903

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LRC15_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LRC15_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LRC15_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CLC11_HUMAN	CLEC11A	physical	28514442
C1GLT_HUMAN	C1GALT1	physical	28514442
FMOD_HUMAN	FMOD	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.