FBX50_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FBX50_HUMAN
• UniProt AC: Q6ZVX7
• Protein Name: F-box only protein 50
• Gene Name: NCCRP1
• Organism: Homo sapiens (Human).
• Sequence Length: 275
• Subcellular Localization: Cytoplasm .
• Protein Description: Promotes cell proliferation..
• Protein Sequence: MEEVREGHALGGGMEADGPASLQELPPSPRSPSPPPSPPPLPSPPSLPSPAAPEAPELPEPAQPSEAHARQLLLEEWGPLSGGLELPQRLTWKLLLLRRPLYRNLLRSPNPEGINIYEPAPPTGPTQRPLETLGNFRGWYIRTEKLQQNQSWTVKQQCVDLLAEGLWEELLDDEQPAITVMDWFEDSRLDACVYELHVWLLAADRRTVIAQHHVAPRTSGRGPPGRWVQVSHVFRHYGPGVRFIHFLHKAKNRMEPGGLRRTRVTDSSVSVQLRE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	MEADGPASLQELPPS CCCCCCCCHHHCCCC		27251275
28	Phosphorylation	SLQELPPSPRSPSPP CHHHCCCCCCCCCCC		23312004
31	Phosphorylation	ELPPSPRSPSPPPSP HCCCCCCCCCCCCCC		28348404
33	Phosphorylation	PPSPRSPSPPPSPPP CCCCCCCCCCCCCCC		28348404
37	Phosphorylation	RSPSPPPSPPPLPSP CCCCCCCCCCCCCCC		28348404
43	Phosphorylation	PSPPPLPSPPSLPSP CCCCCCCCCCCCCCC		28348404
46	Phosphorylation	PPLPSPPSLPSPAAP CCCCCCCCCCCCCCC		27251275
49	Phosphorylation	PSPPSLPSPAAPEAP CCCCCCCCCCCCCCC		27251275
81	Phosphorylation	LEEWGPLSGGLELPQ HHHHCCCCCCCCCCH		24719451
108	Phosphorylation	LYRNLLRSPNPEGIN HHHHHHHCCCCCCCC		25072903
117	Phosphorylation	NPEGINIYEPAPPTG CCCCCCCCCCCCCCC		25072903
123	Phosphorylation	IYEPAPPTGPTQRPL CCCCCCCCCCCCCCH		25072903
126	Phosphorylation	PAPPTGPTQRPLETL CCCCCCCCCCCHHHH		25072903
140	Phosphorylation	LGNFRGWYIRTEKLQ HHCCCCEEEEEHHHH		29396449
218	Phosphorylation	QHHVAPRTSGRGPPG ECCCCCCCCCCCCCC		-
262	Phosphorylation	EPGGLRRTRVTDSSV CCCCCCCCEECCCCE		26074081
265	Phosphorylation	GLRRTRVTDSSVSVQ CCCCCEECCCCEEEE		26074081
267	Phosphorylation	RRTRVTDSSVSVQLR CCCEECCCCEEEEEC		26074081
268	Phosphorylation	RTRVTDSSVSVQLRE CCEECCCCEEEEECC		26074081
270	Phosphorylation	RVTDSSVSVQLRE-- EECCCCEEEEECC--		26074081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FBX50_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FBX50_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FBX50_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of FBX50_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.