HORN_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HORN_HUMAN
• UniProt AC: Q86YZ3
• Protein Name: Hornerin
• Gene Name: HRNR
• Organism: Homo sapiens (Human).
• Sequence Length: 2850
• Subcellular Localization: Cytoplasmic granule . Found in keratohyalin granules in the granular cells of the epidermis.
• Protein Description: Component of the epidermal cornified cell envelopes..
• Protein Sequence: MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQSLDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTSPYEYVQEQRCYFYQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
97	Phosphorylation	GKDYCQVSGSKLRDD CCCCHHCCCCCCCCC	16.09	-
99	Phosphorylation	DYCQVSGSKLRDDTH CCHHCCCCCCCCCCH	22.47	-
115	Phosphorylation	HQEEQEETEKEENKR HHHHHHHHHHHHHHH	52.16	32142685
160	Phosphorylation	ESISRRLSFQRDFSG HHHHHHHCCCCCCCC	19.95	24719451
257	Phosphorylation	GSGHSSGYGQHGSRS CCCCCCCCCCCCCCC	18.63	-
262	Phosphorylation	SGYGQHGSRSGQSSR CCCCCCCCCCCCCCC	22.58	-
267	Phosphorylation	HGSRSGQSSRGERHR CCCCCCCCCCCCCCC	26.06	-
268	Phosphorylation	GSRSGQSSRGERHRS CCCCCCCCCCCCCCC	36.10	-
275	Phosphorylation	SRGERHRSSSGSSSS CCCCCCCCCCCCCCC	23.80	22210691
276	Phosphorylation	RGERHRSSSGSSSSY CCCCCCCCCCCCCCC	38.38	-
279	Phosphorylation	RHRSSSGSSSSYGQH CCCCCCCCCCCCCCC	29.06	-
280	Phosphorylation	HRSSSGSSSSYGQHG CCCCCCCCCCCCCCC	27.16	-
281	Phosphorylation	RSSSGSSSSYGQHGS CCCCCCCCCCCCCCC	29.31	-
283	Phosphorylation	SSGSSSSYGQHGSGS CCCCCCCCCCCCCCC	23.81	-
288	Phosphorylation	SSYGQHGSGSRQSLG CCCCCCCCCCCCCCC	31.32	22210691
290	Phosphorylation	YGQHGSGSRQSLGHG CCCCCCCCCCCCCCC	28.92	22210691
293	Phosphorylation	HGSGSRQSLGHGRQG CCCCCCCCCCCCCCC	34.90	-
301	Phosphorylation	LGHGRQGSGSRQSPS CCCCCCCCCCCCCCC	25.84	-
306	Phosphorylation	QGSGSRQSPSHVRHG CCCCCCCCCCCCCCC	27.53	20068231
308	Phosphorylation	SGSRQSPSHVRHGSG CCCCCCCCCCCCCCC	39.60	20068231
397	Phosphorylation	HGSSSRQSSSYGQHE CCCCCCCCCCCCCCC	21.82	24043423
398	Phosphorylation	GSSSRQSSSYGQHES CCCCCCCCCCCCCCC	21.17	28258704
399	Phosphorylation	SSSRQSSSYGQHESA CCCCCCCCCCCCCCC	38.23	24043423
400	Phosphorylation	SSRQSSSYGQHESAS CCCCCCCCCCCCCCC	23.81	24043423
405	Phosphorylation	SSYGQHESASRHSSG CCCCCCCCCCCCCCC	29.44	24043423
407	Phosphorylation	YGQHESASRHSSGRG CCCCCCCCCCCCCCC	39.54	24043423
417	Phosphorylation	SSGRGQHSSGSGQSP CCCCCCCCCCCCCCC	28.62	22210691
418	Phosphorylation	SGRGQHSSGSGQSPG CCCCCCCCCCCCCCC	34.55	-
423	Phosphorylation	HSSGSGQSPGHGQRG CCCCCCCCCCCCCCC	36.05	22210691
431	Phosphorylation	PGHGQRGSGSGQSPS CCCCCCCCCCCCCCC	31.79	22210691
436	Phosphorylation	RGSGSGQSPSSGQHG CCCCCCCCCCCCCCC	30.21	22210691
438	Phosphorylation	SGSGQSPSSGQHGTG CCCCCCCCCCCCCCC	52.96	-
444	Phosphorylation	PSSGQHGTGFGRSSS CCCCCCCCCCCCCCC	27.49	-
496	Phosphorylation	SGHGQHGSRSGQSSR CCCCCCCCCCCCCCC	22.58	-
501	Phosphorylation	HGSRSGQSSRGERQG CCCCCCCCCCCCCCC	26.06	-
502	Phosphorylation	GSRSGQSSRGERQGS CCCCCCCCCCCCCCC	36.10	-
510	Phosphorylation	RGERQGSSAGSSSSY CCCCCCCCCCCCCCC	43.40	-
516	Phosphorylation	SSAGSSSSYGQHGSG CCCCCCCCCCCCCCC	34.92	-
517	Phosphorylation	SAGSSSSYGQHGSGS CCCCCCCCCCCCCCC	23.81	-
522	Phosphorylation	SSYGQHGSGSRQSLG CCCCCCCCCCCCCCC	31.32	-
524	Phosphorylation	YGQHGSGSRQSLGHS CCCCCCCCCCCCCCC	28.92	-
535	Phosphorylation	LGHSRHGSGSGQSPS CCCCCCCCCCCCCCC	24.54	20068231
537	Phosphorylation	HSRHGSGSGQSPSPS CCCCCCCCCCCCCCC	35.04	20068231
540	Phosphorylation	HGSGSGQSPSPSRGR CCCCCCCCCCCCCCC	30.76	20068231
542	Phosphorylation	SGSGQSPSPSRGRHE CCCCCCCCCCCCCCC	40.53	20068231
544	Phosphorylation	SGQSPSPSRGRHESG CCCCCCCCCCCCCCC	52.27	20068231
558	Phosphorylation	GSRQSSSYGPHGYGS CCCCCCCCCCCCCCC	36.30	25106551
565	Phosphorylation	YGPHGYGSGRSSSRG CCCCCCCCCCCCCCC	23.66	25106551
649	Phosphorylation	GSSQSSRYGQQGSGS CCCCCCCCCCCCCCC	22.64	-
654	Phosphorylation	SRYGQQGSGSGQSPS CCCCCCCCCCCCCCC	26.00	-
656	Phosphorylation	YGQQGSGSGQSPSRG CCCCCCCCCCCCCCC	35.04	20068231
659	Phosphorylation	QGSGSGQSPSRGRHG CCCCCCCCCCCCCCC	28.50	20068231
661	Phosphorylation	SGSGQSPSRGRHGSD CCCCCCCCCCCCCCC	53.25	20068231
731	Phosphorylation	SGYRKHGSRSGQSSR CCCCCCCCCCCCCCC	24.00	-
736	Phosphorylation	HGSRSGQSSRSEQHG CCCCCCCCCCCHHCC	31.11	-
737	Phosphorylation	GSRSGQSSRSEQHGS CCCCCCCCCCHHCCC	31.75	-
744	Phosphorylation	SRSEQHGSSSGLSSS CCCHHCCCCCCCCCC	21.14	-
762	Phosphorylation	HGSGSHQSSGHGRQG CCCCCCCCCCCCCCC	32.63	-
763	Phosphorylation	GSGSHQSSGHGRQGS CCCCCCCCCCCCCCC	28.39	-
770	Phosphorylation	SGHGRQGSGSGHSPS CCCCCCCCCCCCCCC	22.80	24732914
772	Phosphorylation	HGRQGSGSGHSPSRV CCCCCCCCCCCCCCC	34.72	-
775	Phosphorylation	QGSGSGHSPSRVRHG CCCCCCCCCCCCCCC	28.26	24732914
777	Phosphorylation	SGSGHSPSRVRHGSS CCCCCCCCCCCCCCC	46.55	24732914
846	Phosphorylation	SSQGRHGSTSGQSSS CCCCCCCCCCCCCCC	17.18	-
847	Phosphorylation	SQGRHGSTSGQSSSS CCCCCCCCCCCCCCC	41.28	-
851	Phosphorylation	HGSTSGQSSSSGQHD CCCCCCCCCCCCCCC	35.40	-
878	Phosphorylation	ESASHHASGRGRHGS CCCCCCCCCCCCCCC	25.35	-
885	Phosphorylation	SGRGRHGSGSGQSPG CCCCCCCCCCCCCCC	24.54	20068231
887	Phosphorylation	RGRHGSGSGQSPGHG CCCCCCCCCCCCCCC	35.04	20068231
890	Phosphorylation	HGSGSGQSPGHGQRG CCCCCCCCCCCCCCC	36.05	20068231
898	Phosphorylation	PGHGQRGSGSGQSPS CCCCCCCCCCCCCCC	31.79	20068231
903	Phosphorylation	RGSGSGQSPSYGRHG CCCCCCCCCCCCCCC	21.24	21815630
905	Phosphorylation	SGSGQSPSYGRHGSG CCCCCCCCCCCCCCC	45.53	22777824
911	Phosphorylation	PSYGRHGSGSGRSSS CCCCCCCCCCCCCCC	24.54	21712546
913	Phosphorylation	YGRHGSGSGRSSSSG CCCCCCCCCCCCCCC	32.50	21712546
919	Phosphorylation	GSGRSSSSGRHGSGS CCCCCCCCCCCCCCC	41.62	-
962	Phosphorylation	SSYEQHGSRSGQSSR CCCCCCCCCCCCCCC	22.58	-
967	Phosphorylation	HGSRSGQSSRSEQHG CCCCCCCCCCCCCCC	31.11	-
968	Phosphorylation	GSRSGQSSRSEQHGS CCCCCCCCCCCCCCC	31.75	-
970	Phosphorylation	RSGQSSRSEQHGSSS CCCCCCCCCCCCCCC	43.48	30576142
975	Phosphorylation	SRSEQHGSSSGSSSS CCCCCCCCCCCCCCC	21.14	30576142
976	Phosphorylation	RSEQHGSSSGSSSSY CCCCCCCCCCCCCCC	43.22	30576142
977	Phosphorylation	SEQHGSSSGSSSSYG CCCCCCCCCCCCCCC	44.37	25954137
979	Phosphorylation	QHGSSSGSSSSYGQH CCCCCCCCCCCCCCC	29.06	25954137
983	Phosphorylation	SSGSSSSYGQHGSGS CCCCCCCCCCCCCCC	23.81	-
988	Phosphorylation	SSYGQHGSGSRQSLG CCCCCCCCCCCCCCC	31.32	-
990	Phosphorylation	YGQHGSGSRQSLGHG CCCCCCCCCCCCCCC	28.92	-
993	Phosphorylation	HGSGSRQSLGHGQHG CCCCCCCCCCCCCCC	34.90	20068231
1001	Phosphorylation	LGHGQHGSGSGQSPS CCCCCCCCCCCCCCC	27.88	30206219
1003	Phosphorylation	HGQHGSGSGQSPSPS CCCCCCCCCCCCCCC	35.04	30576142
1006	Phosphorylation	HGSGSGQSPSPSRGR CCCCCCCCCCCCCCC	30.76	20068231
1008	Phosphorylation	SGSGQSPSPSRGRHG CCCCCCCCCCCCCCC	40.53	30206219
1010	Phosphorylation	SGQSPSPSRGRHGSG CCCCCCCCCCCCCCC	52.27	30576142
1028	Methylation	SSSYGPYRSGSGWSS CCCCCCCCCCCCCCC	37.36	115387515
1037	Methylation	GSGWSSSRGPYESGS CCCCCCCCCCCCCCC	52.64	115387519
1048	Phosphorylation	ESGSGHSSGLGHRES CCCCCCCCCCCCCCC	32.15	-
1110	Phosphorylation	GQHGSGSSQSSGYGR CCCCCCCCCCCCCCC	37.29	-
1113	Phosphorylation	GSGSSQSSGYGRQGS CCCCCCCCCCCCCCC	28.53	-
1115	Phosphorylation	GSSQSSGYGRQGSGS CCCCCCCCCCCCCCC	15.87	-
1120	Phosphorylation	SGYGRQGSGSGQSPG CCCCCCCCCCCCCCC	22.80	20068231
1122	Phosphorylation	YGRQGSGSGQSPGHG CCCCCCCCCCCCCCC	35.04	20068231
1125	Phosphorylation	QGSGSGQSPGHGQRG CCCCCCCCCCCCCCC	36.05	20068231
1138	Phosphorylation	RGSGSRQSPSYGRHG CCCCCCCCCCCCCCC	18.07	19664995
1140	Phosphorylation	SGSRQSPSYGRHGSG CCCCCCCCCCCCCCC	45.53	22777824
1146	Phosphorylation	PSYGRHGSGSGRSSS CCCCCCCCCCCCCCC	24.54	-
1148	Phosphorylation	YGRHGSGSGRSSSSG CCCCCCCCCCCCCCC	32.50	24505115
1154	Phosphorylation	GSGRSSSSGQHGSGL CCCCCCCCCCCCCCC	44.41	-
1159	Phosphorylation	SSSGQHGSGLGESSG CCCCCCCCCCCCCCC	28.81	-
1172	Phosphorylation	SGFGHHESSSGQSSS CCCCCCCCCCCCCCC	26.00	-
1193	Phosphorylation	GSGHSSGYGQHGSRS CCCCCCCCCCCCCCC	18.63	-
1198	Phosphorylation	SGYGQHGSRSGQSSR CCCCCCCCCCCCCCC	22.58	-
1203	Phosphorylation	HGSRSGQSSRGERHG CCCCCCCCCCCCCCC	26.06	-
1204	Phosphorylation	GSRSGQSSRGERHGS CCCCCCCCCCCCCCC	36.10	-
1205	Methylation	SRSGQSSRGERHGSS CCCCCCCCCCCCCCC	57.13	-
1211	Phosphorylation	SRGERHGSSSGSSSH CCCCCCCCCCCCCCC	18.40	-
1212	Phosphorylation	RGERHGSSSGSSSHY CCCCCCCCCCCCCCC	43.22	-
1213	Phosphorylation	GERHGSSSGSSSHYG CCCCCCCCCCCCCCC	44.37	-
1219	Phosphorylation	SSGSSSHYGQHGSGS CCCCCCCCCCCCCCC	22.04	-
1224	Phosphorylation	SHYGQHGSGSRQSSG CCCCCCCCCCCCCCC	31.32	-
1226	Phosphorylation	YGQHGSGSRQSSGHG CCCCCCCCCCCCCCC	28.92	-
1229	Phosphorylation	HGSGSRQSSGHGRQG CCCCCCCCCCCCCCC	36.86	-
1230	Phosphorylation	GSGSRQSSGHGRQGS CCCCCCCCCCCCCCC	26.86	-
1237	Phosphorylation	SGHGRQGSGSGHSPS CCCCCCCCCCCCCCC	22.80	24732914
1239	Phosphorylation	HGRQGSGSGHSPSRG CCCCCCCCCCCCCCC	34.72	-
1242	Phosphorylation	QGSGSGHSPSRGRHG CCCCCCCCCCCCCCC	28.26	24732914
1244	Phosphorylation	SGSGHSPSRGRHGSG CCCCCCCCCCCCCCC	50.83	24732914
1250	Phosphorylation	PSRGRHGSGLGHSSS CCCCCCCCCCCCCCC	25.39	-
1257	Phosphorylation	SGLGHSSSHGQHGSG CCCCCCCCCCCCCCC	34.35	-
1274	Phosphorylation	RSSSRGPYESRSGHS CCCCCCCCCCCCCCC	29.39	22461510
1276	Phosphorylation	SSRGPYESRSGHSSV CCCCCCCCCCCCCCC	26.38	-
1294	Phosphorylation	HESGSGHSSAYSQHG CCCCCCCCCCCCCCC	21.86	-
1295	Phosphorylation	ESGSGHSSAYSQHGS CCCCCCCCCCCCCCC	26.08	-
1344	Phosphorylation	GHRGSGSSQSSGYGR CCCCCCCCCCCCCCC	37.29	-
1347	Phosphorylation	GSGSSQSSGYGRHGA CCCCCCCCCCCCCCC	28.53	-
1349	Phosphorylation	GSSQSSGYGRHGAGS CCCCCCCCCCCCCCC	16.97	-
1361	Phosphorylation	AGSGQSPSRGRHGSG CCCCCCCCCCCCCCC	53.25	-
1367	Phosphorylation	PSRGRHGSGSGHSSS CCCCCCCCCCCCCCC	24.54	28270605
1369	Phosphorylation	RGRHGSGSGHSSSYG CCCCCCCCCCCCCCC	34.72	28270605
1372	Phosphorylation	HGSGSGHSSSYGQHG CCCCCCCCCCCCCCC	25.22	28270605
1373	Phosphorylation	GSGSGHSSSYGQHGS CCCCCCCCCCCCCCC	23.16	28270605
1374	Phosphorylation	SGSGHSSSYGQHGSG CCCCCCCCCCCCCCC	35.98	28270605
1375	Phosphorylation	GSGHSSSYGQHGSGS CCCCCCCCCCCCCCC	23.81	28270605
1432	Phosphorylation	SSYEQHGSRSGQSSR CCCCCCCCCCCCCCC	22.58	-
1437	Phosphorylation	HGSRSGQSSRGERHG CCCCCCCCCCCCCCC	26.06	-
1438	Phosphorylation	GSRSGQSSRGERHGS CCCCCCCCCCCCCCC	36.10	-
1445	Phosphorylation	SRGERHGSSSGSSSS CCCCCCCCCCCCCCC	18.40	25954137
1446	Phosphorylation	RGERHGSSSGSSSSY CCCCCCCCCCCCCCC	43.22	25954137
1447	Phosphorylation	GERHGSSSGSSSSYG CCCCCCCCCCCCCCC	44.37	25954137
1449	Phosphorylation	RHGSSSGSSSSYGQH CCCCCCCCCCCCCCC	29.06	25954137
1453	Phosphorylation	SSGSSSSYGQHGSGS CCCCCCCCCCCCCCC	23.81	-
1458	Phosphorylation	SSYGQHGSGSRQSLG CCCCCCCCCCCCCCC	31.32	-
1460	Phosphorylation	YGQHGSGSRQSLGHG CCCCCCCCCCCCCCC	28.92	-
1463	Phosphorylation	HGSGSRQSLGHGQHG CCCCCCCCCCCCCCC	34.90	20068231
1471	Phosphorylation	LGHGQHGSGSGQSPS CCCCCCCCCCCCCCC	27.88	30206219
1473	Phosphorylation	HGQHGSGSGQSPSPS CCCCCCCCCCCCCCC	35.04	20068231
1476	Phosphorylation	HGSGSGQSPSPSRGR CCCCCCCCCCCCCCC	30.76	20068231
1478	Phosphorylation	SGSGQSPSPSRGRHG CCCCCCCCCCCCCCC	40.53	23401153
1480	Phosphorylation	SGQSPSPSRGRHGSG CCCCCCCCCCCCCCC	52.27	20068231
1488	Phosphorylation	RGRHGSGSGQSSSYS CCCCCCCCCCCCCCC	35.04	30576142
1499	Phosphorylation	SSYSPYGSGSGWSSS CCCCCCCCCCCCCCC	24.76	30576142
1501	Phosphorylation	YSPYGSGSGWSSSRG CCCCCCCCCCCCCCC	38.49	-
1506	Phosphorylation	SGSGWSSSRGPYESG CCCCCCCCCCCCCCC	35.42	30576142
1507	Methylation	GSGWSSSRGPYESGS CCCCCCCCCCCCCCC	52.64	-
1580	Phosphorylation	GQHGSGSSQSSGYGR CCCCCCCCCCCCCCC	37.29	-
1583	Phosphorylation	GSGSSQSSGYGRQGS CCCCCCCCCCCCCCC	28.53	-
1585	Phosphorylation	GSSQSSGYGRQGSGS CCCCCCCCCCCCCCC	15.87	-
1590	Phosphorylation	SGYGRQGSGSGQSPG CCCCCCCCCCCCCCC	22.80	20068231
1592	Phosphorylation	YGRQGSGSGQSPGHG CCCCCCCCCCCCCCC	35.04	20068231
1595	Phosphorylation	QGSGSGQSPGHGQRG CCCCCCCCCCCCCCC	36.05	20068231
1608	Phosphorylation	RGSGSRQSPSYGRHG CCCCCCCCCCCCCCC	18.07	19664995
1610	Phosphorylation	SGSRQSPSYGRHGSG CCCCCCCCCCCCCCC	45.53	22777824
1616	Phosphorylation	PSYGRHGSGSGRSSS CCCCCCCCCCCCCCC	24.54	-
1618	Phosphorylation	YGRHGSGSGRSSSSG CCCCCCCCCCCCCCC	32.50	24505115
1624	Phosphorylation	GSGRSSSSGQHGSGL CCCCCCCCCCCCCCC	44.41	-
1629	Phosphorylation	SSSGQHGSGLGESSG CCCCCCCCCCCCCCC	28.81	-
1642	Phosphorylation	SGFGHHESSSGQSSS CCCCCCCCCCCCCCC	26.00	-
1663	Phosphorylation	GSGHSSGYGQHGSRS CCCCCCCCCCCCCCC	18.63	-
1668	Phosphorylation	SGYGQHGSRSGQSSR CCCCCCCCCCCCCCC	22.58	-
1673	Phosphorylation	HGSRSGQSSRGERHG CCCCCCCCCCCCCCC	26.06	-
1674	Phosphorylation	GSRSGQSSRGERHGS CCCCCCCCCCCCCCC	36.10	-
1681	Phosphorylation	SRGERHGSSSRSSSR CCCCCCCCCCCCCCC	21.00	-
1682	Phosphorylation	RGERHGSSSRSSSRY CCCCCCCCCCCCCCC	34.07	-
1685	Phosphorylation	RHGSSSRSSSRYGQH CCCCCCCCCCCCCCC	34.31	28258704
1686	Phosphorylation	HGSSSRSSSRYGQHG CCCCCCCCCCCCCCC	20.09	-
1689	Phosphorylation	SSRSSSRYGQHGSGS CCCCCCCCCCCCCCC	24.08	-
1694	Phosphorylation	SRYGQHGSGSRQSSG CCCCCCCCCCCCCCC	31.32	-
1696	Phosphorylation	YGQHGSGSRQSSGHG CCCCCCCCCCCCCCC	28.92	-
1699	Phosphorylation	HGSGSRQSSGHGRQG CCCCCCCCCCCCCCC	36.86	-
1700	Phosphorylation	GSGSRQSSGHGRQGS CCCCCCCCCCCCCCC	26.86	-
1707	Phosphorylation	SGHGRQGSGSGQSPS CCCCCCCCCCCCCCC	22.80	-
1709	Phosphorylation	HGRQGSGSGQSPSRG CCCCCCCCCCCCCCC	35.04	20068231
1712	Phosphorylation	QGSGSGQSPSRGRHG CCCCCCCCCCCCCCC	28.50	20068231
1714	Phosphorylation	SGSGQSPSRGRHGSG CCCCCCCCCCCCCCC	53.25	20068231
1720	Phosphorylation	PSRGRHGSGLGHSSS CCCCCCCCCCCCCCC	25.39	-
1727	Phosphorylation	SGLGHSSSHGQHGSG CCCCCCCCCCCCCCC	34.35	-
1744	Phosphorylation	RSSSRGPYESRSGHS CCCCCCCCCCCCCCC	29.39	22461510
1746	Phosphorylation	SSRGPYESRSGHSSV CCCCCCCCCCCCCCC	26.38	-
1764	Phosphorylation	HESGSGHSSAYSQHG CCCCCCCCCCCCCCC	21.86	-
1765	Phosphorylation	ESGSGHSSAYSQHGS CCCCCCCCCCCCCCC	26.08	-
1824	Phosphorylation	SSYGQQGSGSGQSPS CCCCCCCCCCCCCCC	26.00	-
1826	Phosphorylation	YGQQGSGSGQSPSRG CCCCCCCCCCCCCCC	35.04	20068231
1829	Phosphorylation	QGSGSGQSPSRGRHG CCCCCCCCCCCCCCC	28.50	20068231
1831	Phosphorylation	SGSGQSPSRGRHGSG CCCCCCCCCCCCCCC	53.25	20068231
1837	Phosphorylation	PSRGRHGSGSGHSSS CCCCCCCCCCCCCCC	24.54	28270605
1839	Phosphorylation	RGRHGSGSGHSSSYG CCCCCCCCCCCCCCC	34.72	28270605
1842	Phosphorylation	HGSGSGHSSSYGQHG CCCCCCCCCCCCCCC	25.22	28270605
1843	Phosphorylation	GSGSGHSSSYGQHGS CCCCCCCCCCCCCCC	23.16	28270605
1844	Phosphorylation	SGSGHSSSYGQHGSG CCCCCCCCCCCCCCC	35.98	28270605
1845	Phosphorylation	GSGHSSSYGQHGSGS CCCCCCCCCCCCCCC	23.81	28270605
1902	Phosphorylation	SSYEQHGSRSGQSSR CCCCCCCCCCCCCCC	22.58	-
1907	Phosphorylation	HGSRSGQSSRGEQHG CCCCCCCCCCCCCCC	26.06	-
1908	Phosphorylation	GSRSGQSSRGEQHGS CCCCCCCCCCCCCCC	36.10	-
1915	Phosphorylation	SRGEQHGSSSGSSSS CCCCCCCCCCCCCCC	21.14	25954137
1916	Phosphorylation	RGEQHGSSSGSSSSY CCCCCCCCCCCCCCC	43.22	25954137
1917	Phosphorylation	GEQHGSSSGSSSSYG CCCCCCCCCCCCCCC	44.37	25954137
1919	Phosphorylation	QHGSSSGSSSSYGQH CCCCCCCCCCCCCCC	29.06	25954137
1923	Phosphorylation	SSGSSSSYGQHGSGS CCCCCCCCCCCCCCC	23.81	-
1928	Phosphorylation	SSYGQHGSGSRQSLG CCCCCCCCCCCCCCC	31.32	-
1930	Phosphorylation	YGQHGSGSRQSLGHG CCCCCCCCCCCCCCC	28.92	20068231
1933	Phosphorylation	HGSGSRQSLGHGQHG CCCCCCCCCCCCCCC	34.90	20068231
1941	Phosphorylation	LGHGQHGSGSGQSPS CCCCCCCCCCCCCCC	27.88	30206219
1943	Phosphorylation	HGQHGSGSGQSPSPS CCCCCCCCCCCCCCC	35.04	20068231
1946	Phosphorylation	HGSGSGQSPSPSRGR CCCCCCCCCCCCCCC	30.76	20068231
1948	Phosphorylation	SGSGQSPSPSRGRHG CCCCCCCCCCCCCCC	40.53	23401153
1950	Phosphorylation	SGQSPSPSRGRHGSG CCCCCCCCCCCCCCC	52.27	20068231
1977	Methylation	GSGWSSSRGPYESGS CCCCCCCCCCCCCCC	52.64	-
1988	Phosphorylation	ESGSGHSSGLGHRES CCCCCCCCCCCCCCC	32.15	-
2050	Phosphorylation	GQHGSGSSQSSGYGR CCCCCCCCCCCCCCC	37.29	-
2053	Phosphorylation	GSGSSQSSGYGRQGS CCCCCCCCCCCCCCC	28.53	-
2055	Phosphorylation	GSSQSSGYGRQGSGS CCCCCCCCCCCCCCC	15.87	-
2060	Phosphorylation	SGYGRQGSGSGQSPG CCCCCCCCCCCCCCC	22.80	20068231
2062	Phosphorylation	YGRQGSGSGQSPGHG CCCCCCCCCCCCCCC	35.04	20068231
2065	Phosphorylation	QGSGSGQSPGHGQRG CCCCCCCCCCCCCCC	36.05	20068231
2078	Phosphorylation	RGSGSRQSPSYGRHG CCCCCCCCCCCCCCC	18.07	19664995
2080	Phosphorylation	SGSRQSPSYGRHGSG CCCCCCCCCCCCCCC	45.53	22777824
2086	Phosphorylation	PSYGRHGSGSGRSSS CCCCCCCCCCCCCCC	24.54	-
2088	Phosphorylation	YGRHGSGSGRSSSSG CCCCCCCCCCCCCCC	32.50	24505115
2091	Phosphorylation	HGSGSGRSSSSGQHG CCCCCCCCCCCCCCC	37.79	30576142
2094	Phosphorylation	GSGRSSSSGQHGPGL CCCCCCCCCCCCCCC	44.41	30576142
2104	Phosphorylation	HGPGLGESSGFGHHE CCCCCCCCCCCCCCC	33.68	30576142
2112	Phosphorylation	SGFGHHESSSGQSSS CCCCCCCCCCCCCCC	26.00	-
2133	Phosphorylation	GSGHSSGYGQHGSRS CCCCCCCCCCCCCCC	18.63	-
2138	Phosphorylation	SGYGQHGSRSGQSSR CCCCCCCCCCCCCCC	22.58	-
2143	Phosphorylation	HGSRSGQSSRGERHG CCCCCCCCCCCCCCC	26.06	-
2144	Phosphorylation	GSRSGQSSRGERHGS CCCCCCCCCCCCCCC	36.10	-
2159	Phosphorylation	SSGSSSRYGQHGSGS CCCCCCCCCCCCCCC	24.08	-
2164	Phosphorylation	SRYGQHGSGSRQSSG CCCCCCCCCCCCCCC	31.32	30576142
2166	Phosphorylation	YGQHGSGSRQSSGHG CCCCCCCCCCCCCCC	28.92	-
2169	Phosphorylation	HGSGSRQSSGHGRQG CCCCCCCCCCCCCCC	36.86	30576142
2170	Phosphorylation	GSGSRQSSGHGRQGS CCCCCCCCCCCCCCC	26.86	30576142
2177	Phosphorylation	SGHGRQGSGSGHSPS CCCCCCCCCCCCCCC	22.80	24732914
2179	Phosphorylation	HGRQGSGSGHSPSRG CCCCCCCCCCCCCCC	34.72	-
2182	Phosphorylation	QGSGSGHSPSRGRHG CCCCCCCCCCCCCCC	28.26	24732914
2184	Phosphorylation	SGSGHSPSRGRHGSG CCCCCCCCCCCCCCC	50.83	24732914
2187	Methylation	GHSPSRGRHGSGSGH CCCCCCCCCCCCCCC	29.86	115387523
2190	Phosphorylation	PSRGRHGSGSGHSSS CCCCCCCCCCCCCCC	24.54	-
2214	Phosphorylation	RSSSRGPYESRSGHS CCCCCCCCCCCCCCC	29.39	22461510
2216	Phosphorylation	SSRGPYESRSGHSSV CCCCCCCCCCCCCCC	26.38	-
2234	Phosphorylation	HESGSGHSSAYSQHG CCCCCCCCCCCCCCC	21.86	-
2235	Phosphorylation	ESGSGHSSAYSQHGS CCCCCCCCCCCCCCC	26.08	-
2294	Phosphorylation	SSYGQQGSGSGQSPS CCCCCCCCCCCCCCC	26.00	-
2296	Phosphorylation	YGQQGSGSGQSPSRG CCCCCCCCCCCCCCC	35.04	20068231
2299	Phosphorylation	QGSGSGQSPSRGRHG CCCCCCCCCCCCCCC	28.50	20068231
2301	Phosphorylation	SGSGQSPSRGRHGSG CCCCCCCCCCCCCCC	53.25	20068231
2307	Phosphorylation	PSRGRHGSGSGHSSS CCCCCCCCCCCCCCC	24.54	28270605
2309	Phosphorylation	RGRHGSGSGHSSSYG CCCCCCCCCCCCCCC	34.72	28270605
2312	Phosphorylation	HGSGSGHSSSYGQHG CCCCCCCCCCCCCCC	25.22	28270605
2313	Phosphorylation	GSGSGHSSSYGQHGS CCCCCCCCCCCCCCC	23.16	28270605
2314	Phosphorylation	SGSGHSSSYGQHGSG CCCCCCCCCCCCCCC	35.98	28270605
2315	Phosphorylation	GSGHSSSYGQHGSGS CCCCCCCCCCCCCCC	23.81	28270605
2372	Phosphorylation	SSYEQHGSRSGQSSR CCCCCCCCCCCCCCC	22.58	-
2377	Phosphorylation	HGSRSGQSSRGERHG CCCCCCCCCCCCCCC	26.06	-
2378	Phosphorylation	GSRSGQSSRGERHGS CCCCCCCCCCCCCCC	36.10	-
2385	Phosphorylation	SRGERHGSSSGSSSS CCCCCCCCCCCCCCC	18.40	25954137
2386	Phosphorylation	RGERHGSSSGSSSSY CCCCCCCCCCCCCCC	43.22	25954137
2387	Phosphorylation	GERHGSSSGSSSSYG CCCCCCCCCCCCCCC	44.37	25954137
2389	Phosphorylation	RHGSSSGSSSSYGQH CCCCCCCCCCCCCCC	29.06	25954137
2393	Phosphorylation	SSGSSSSYGQHGSGS CCCCCCCCCCCCCCC	23.81	-
2398	Phosphorylation	SSYGQHGSGSRQSLG CCCCCCCCCCCCCCC	31.32	-
2400	Phosphorylation	YGQHGSGSRQSLGHG CCCCCCCCCCCCCCC	28.92	-
2403	Phosphorylation	HGSGSRQSLGHGQHG CCCCCCCCCCCCCCC	34.90	20068231
2411	Phosphorylation	LGHGQHGSGSGQSPS CCCCCCCCCCCCCCC	27.88	30206219
2413	Phosphorylation	HGQHGSGSGQSPSPS CCCCCCCCCCCCCCC	35.04	20068231
2416	Phosphorylation	HGSGSGQSPSPSRGR CCCCCCCCCCCCCCC	30.76	20068231
2418	Phosphorylation	SGSGQSPSPSRGRHG CCCCCCCCCCCCCCC	40.53	23401153
2420	Phosphorylation	SGQSPSPSRGRHGSG CCCCCCCCCCCCCCC	52.27	20068231
2441	Phosphorylation	YSPYGSGSGWSSSRG CCCCCCCCCCCCCCC	38.49	-
2447	Methylation	GSGWSSSRGPYESGS CCCCCCCCCCCCCCC	52.64	-
2458	Phosphorylation	ESGSGHSSGLGHRES CCCCCCCCCCCCCCC	32.15	-
2520	Phosphorylation	GQHGSGSSQSSGYGR CCCCCCCCCCCCCCC	37.29	-
2523	Phosphorylation	GSGSSQSSGYGRQGS CCCCCCCCCCCCCCC	28.53	-
2525	Phosphorylation	GSSQSSGYGRQGSGS CCCCCCCCCCCCCCC	15.87	-
2530	Phosphorylation	SGYGRQGSGSGQSPG CCCCCCCCCCCCCCC	22.80	20068231
2532	Phosphorylation	YGRQGSGSGQSPGHG CCCCCCCCCCCCCCC	35.04	20068231
2535	Phosphorylation	QGSGSGQSPGHGQRG CCCCCCCCCCCCCCC	36.05	20068231
2548	Phosphorylation	RGSGSRQSPSYGRHG CCCCCCCCCCCCCCC	18.07	19664995
2550	Phosphorylation	SGSRQSPSYGRHGSG CCCCCCCCCCCCCCC	45.53	22777824
2556	Phosphorylation	PSYGRHGSGSGRSSS CCCCCCCCCCCCCCC	24.54	-
2558	Phosphorylation	YGRHGSGSGRSSSSG CCCCCCCCCCCCCCC	32.50	24505115
2564	Phosphorylation	GSGRSSSSGQHGSGL CCCCCCCCCCCCCCC	44.41	-
2569	Phosphorylation	SSSGQHGSGLGESSG CCCCCCCCCCCCCCC	28.81	-
2582	Phosphorylation	SGFGHHESSSGQSSS CCCCCCCCCCCCCCC	26.00	-
2603	Phosphorylation	GSGHSSGYGQHGSRS CCCCCCCCCCCCCCC	18.63	-
2608	Phosphorylation	SGYGQHGSRSGQSSR CCCCCCCCCCCCCCC	22.58	-
2613	Phosphorylation	HGSRSGQSSRGERHG CCCCCCCCCCCCCCC	26.06	-
2614	Phosphorylation	GSRSGQSSRGERHGS CCCCCCCCCCCCCCC	36.10	-
2621	Phosphorylation	SRGERHGSSSGSSSH CCCCCCCCCCCCCCC	18.40	-
2622	Phosphorylation	RGERHGSSSGSSSHY CCCCCCCCCCCCCCC	43.22	-
2623	Phosphorylation	GERHGSSSGSSSHYG CCCCCCCCCCCCCCC	44.37	30576142
2629	Phosphorylation	SSGSSSHYGQHGSGS CCCCCCCCCCCCCCC	22.04	-
2634	Phosphorylation	SHYGQHGSGSRQSSG CCCCCCCCCCCCCCC	31.32	-
2636	Phosphorylation	YGQHGSGSRQSSGHG CCCCCCCCCCCCCCC	28.92	-
2639	Phosphorylation	HGSGSRQSSGHGRQG CCCCCCCCCCCCCCC	36.86	30576142
2640	Phosphorylation	GSGSRQSSGHGRQGS CCCCCCCCCCCCCCC	26.86	30576142
2647	Phosphorylation	SGHGRQGSGSGQSPS CCCCCCCCCCCCCCC	22.80	-
2649	Phosphorylation	HGRQGSGSGQSPSRG CCCCCCCCCCCCCCC	35.04	20068231
2652	Phosphorylation	QGSGSGQSPSRGRHG CCCCCCCCCCCCCCC	28.50	20068231
2654	Phosphorylation	SGSGQSPSRGRHGSG CCCCCCCCCCCCCCC	53.25	20068231
2660	Phosphorylation	PSRGRHGSGLGHSSS CCCCCCCCCCCCCCC	25.39	-
2667	Phosphorylation	SGLGHSSSHGQHGSG CCCCCCCCCCCCCCC	34.35	-
2684	Phosphorylation	RSSSRGPYESRLGHS CCCCCCCCHHHCCCC	29.39	22461510
2686	Phosphorylation	SSRGPYESRLGHSSV CCCCCCHHHCCCCCC	27.28	-
2704	Phosphorylation	HESGSGHSSAYSQHG CCCCCCCCCCCCCCC	21.86	-
2705	Phosphorylation	ESGSGHSSAYSQHGS CCCCCCCCCCCCCCC	26.08	-
2754	Phosphorylation	GHRGSGSSQSSGYGR CCCCCCCCCCCCCCC	37.29	-
2757	Phosphorylation	GSGSSQSSGYGRHGA CCCCCCCCCCCCCCC	28.53	-
2759	Phosphorylation	GSSQSSGYGRHGAGS CCCCCCCCCCCCCCC	16.97	-
2817	Phosphorylation	YSYCKGGSNHDGGSS CCCCCCCCCCCCCCC	39.39	24043423
2823	Phosphorylation	GSNHDGGSSGSYFLS CCCCCCCCCCCEEEE	36.74	24043423
2824	Phosphorylation	SNHDGGSSGSYFLSF CCCCCCCCCCEEEEC	34.72	24043423
2826	Phosphorylation	HDGGSSGSYFLSFPS CCCCCCCCEEEECCC	18.05	24043423
2827	Phosphorylation	DGGSSGSYFLSFPSS CCCCCCCEEEECCCC	16.44	24043423
2830	Phosphorylation	SSGSYFLSFPSSTSP CCCCEEEECCCCCCC	25.80	24043423
2833	Phosphorylation	SYFLSFPSSTSPYEY CEEEECCCCCCCCHH	44.21	24043423
2834	Phosphorylation	YFLSFPSSTSPYEYV EEEECCCCCCCCHHH	32.89	24043423
2835	Phosphorylation	FLSFPSSTSPYEYVQ EEECCCCCCCCHHHH	37.75	24043423
2836	Phosphorylation	LSFPSSTSPYEYVQE EECCCCCCCCHHHHC	27.68	24043423
2838	Phosphorylation	FPSSTSPYEYVQEQR CCCCCCCCHHHHCCC	21.47	24043423
2840	Phosphorylation	SSTSPYEYVQEQRCY CCCCCCHHHHCCCCE	11.11	24043423

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HORN_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HORN_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HORN_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of HORN_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale proteomics analysis of the human kinome.";
Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.;
Mol. Cell. Proteomics 8:1751-1764(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2411 AND SER-2416, ANDMASS SPECTROMETRY.
PubMed: 19369195