| UniProt ID | STK26_HUMAN | |
|---|---|---|
| UniProt AC | Q9P289 | |
| Protein Name | Serine/threonine-protein kinase 26 {ECO:0000305} | |
| Gene Name | STK26 {ECO:0000312|HGNC:HGNC:18174} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 416 | |
| Subcellular Localization | Cytoplasm . Golgi apparatus . Colocalized with RIPOR1 in the Golgi of serum-starved cells and relocated to cytoplasmic punctae, probably vesicular compartments, along with RIPOR1 upon serum stimulation in a Rho- and PDCD10-dependent manner (PubMed:27 | |
| Protein Description | Mediator of cell growth. [PubMed: 11641781] | |
| Protein Sequence | MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFKRWKAEGHSDDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAEQDLVQTLSCLSMIITPAFAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEKFQKCSADESP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MAHSPVAVQ ------CCCCCEEEE | 19369195 | ||
| 4 | Phosphorylation | ----MAHSPVAVQVP ----CCCCCEEEECC | 29255136 | ||
| 4 (in isoform 2) | Phosphorylation | - | 20068231 | ||
| 16 (in isoform 2) | Phosphorylation | - | 24043423 | ||
| 24 (in isoform 2) | Phosphorylation | - | 24043423 | ||
| 25 | Phosphorylation | ADPEELFTKLERIGK CCHHHHHHHHHHHCC | 22199227 | ||
| 26 | Ubiquitination | DPEELFTKLERIGKG CHHHHHHHHHHHCCC | 24816145 | ||
| 29 (in isoform 2) | Phosphorylation | - | 24043423 | ||
| 32 | Ubiquitination | TKLERIGKGSFGEVF HHHHHHCCCCHHHHC | 24816145 | ||
| 34 | Phosphorylation | LERIGKGSFGEVFKG HHHHCCCCHHHHCCC | 20873877 | ||
| 40 | Ubiquitination | GSFGEVFKGIDNRTQ CCHHHHCCCCCCCCC | 21890473 | ||
| 40 | Acetylation | GSFGEVFKGIDNRTQ CCHHHHCCCCCCCCC | 26822725 | ||
| 40 | Ubiquitination | GSFGEVFKGIDNRTQ CCHHHHCCCCCCCCC | 21890473 | ||
| 41 | Ubiquitination | SFGEVFKGIDNRTQQ CHHHHCCCCCCCCCE | 27667366 | ||
| 47 | Ubiquitination | KGIDNRTQQVVAIKI CCCCCCCCEEEEEEE | 22817900 | ||
| 48 | Ubiquitination | GIDNRTQQVVAIKII CCCCCCCEEEEEEEE | 22817900 | ||
| 53 | Ubiquitination | TQQVVAIKIIDLEEA CCEEEEEEEEEHHHH | 29967540 | ||
| 62 | Ubiquitination | IDLEEAEDEIEDIQQ EEHHHHHHHHHHHHH | 27667366 | ||
| 69 | Ubiquitination | DEIEDIQQEITVLSQ HHHHHHHHHHHHHHH | 22817900 | ||
| 76 | Ubiquitination | QEITVLSQCDSSYVT HHHHHHHHCCCHHHH | 22505724 | ||
| 77 | Ubiquitination | EITVLSQCDSSYVTK HHHHHHHCCCHHHHH | 22505724 | ||
| 82 | Ubiquitination | SQCDSSYVTKYYGSY HHCCCHHHHHHHHHH | 29967540 | ||
| 86 | Phosphorylation | SSYVTKYYGSYLKGS CHHHHHHHHHHCCCC | - | ||
| 89 | Phosphorylation | VTKYYGSYLKGSKLW HHHHHHHHCCCCEEE | - | ||
| 91 | Ubiquitination | KYYGSYLKGSKLWII HHHHHHCCCCEEEEE | 29967540 | ||
| 98 | Ubiquitination | KGSKLWIIMEYLGGG CCCEEEEEEEHHCCC | 32015554 | ||
| 101 | Phosphorylation | KLWIIMEYLGGGSAL EEEEEEEHHCCCCHH | 32645325 | ||
| 106 | Phosphorylation | MEYLGGGSALDLLRA EEHHCCCCHHHHHHH | 20873877 | ||
| 130 | Acetylation | TMLKEILKGLDYLHS HHHHHHHHHHHHHHC | 26822725 | ||
| 130 | Malonylation | TMLKEILKGLDYLHS HHHHHHHHHHHHHHC | 26320211 | ||
| 130 | Ubiquitination | TMLKEILKGLDYLHS HHHHHHHHHHHHHHC | 29967540 | ||
| 134 | Ubiquitination | EILKGLDYLHSEKKI HHHHHHHHHHCCCHH | 21890473 | ||
| 135 | Ubiquitination | ILKGLDYLHSEKKIH HHHHHHHHHCCCHHH | 21890473 | ||
| 139 | Ubiquitination | LDYLHSEKKIHRDIK HHHHHCCCHHHHCHH | 27667366 | ||
| 146 | Ubiquitination | KKIHRDIKAANVLLS CHHHHCHHHHHHHHC | 21906983 | ||
| 147 | Ubiquitination | KIHRDIKAANVLLSE HHHHCHHHHHHHHCC | 21890473 | ||
| 156 | Ubiquitination | NVLLSEQGDVKLADF HHHHCCCCCCCCCCE | 21890473 | ||
| 156 | Ubiquitination | NVLLSEQGDVKLADF HHHHCCCCCCCCCCE | 21890473 | ||
| 159 | Ubiquitination | LSEQGDVKLADFGVA HCCCCCCCCCCEECC | 29967540 | ||
| 168 | Ubiquitination | ADFGVAGQLTDTQIK CCEECCCCCCCCCHH | 21890473 | ||
| 168 | Ubiquitination | ADFGVAGQLTDTQIK CCEECCCCCCCCCHH | 21890473 | ||
| 170 | Phosphorylation | FGVAGQLTDTQIKRN EECCCCCCCCCHHHC | 30266825 | ||
| 171 | Ubiquitination | GVAGQLTDTQIKRNT ECCCCCCCCCHHHCC | 29967540 | ||
| 172 | Phosphorylation | VAGQLTDTQIKRNTF CCCCCCCCCHHHCCC | 29255136 | ||
| 175 | Ubiquitination | QLTDTQIKRNTFVGT CCCCCCHHHCCCCCC | 32015554 | ||
| 178 | Phosphorylation | DTQIKRNTFVGTPFW CCCHHHCCCCCCCCC | 23401153 | ||
| 178 (in isoform 3) | Phosphorylation | - | 22210691 | ||
| 180 | Ubiquitination | QIKRNTFVGTPFWMA CHHHCCCCCCCCCCC | 29967540 | ||
| 181 | Ubiquitination | IKRNTFVGTPFWMAP HHHCCCCCCCCCCCH | 21890473 | ||
| 182 | Phosphorylation | KRNTFVGTPFWMAPE HHCCCCCCCCCCCHH | 22322096 | ||
| 182 | Ubiquitination | KRNTFVGTPFWMAPE HHCCCCCCCCCCCHH | 21890473 | ||
| 182 (in isoform 3) | Phosphorylation | - | 22210691 | ||
| 189 | Ubiquitination | TPFWMAPEVIQQSAY CCCCCCHHHHHHHCC | 29967540 | ||
| 194 | Phosphorylation | APEVIQQSAYDSKAD CHHHHHHHCCCCHHH | 23312004 | ||
| 199 | Ubiquitination | QQSAYDSKADIWSLG HHHCCCCHHHHHHHC | 29967540 | ||
| 203 | Ubiquitination | YDSKADIWSLGITAI CCCHHHHHHHCHHHH | 21890473 | ||
| 214 | Ubiquitination | ITAIELAKGEPPNSD HHHHHHHCCCCCCCC | - | ||
| 218 | Ubiquitination | ELAKGEPPNSDMHPM HHHCCCCCCCCCCCE | 21890473 | ||
| 223 | Phosphorylation | EPPNSDMHPMRVLFL CCCCCCCCCEEEEEE | 33259812 | ||
| 233 | Sumoylation | RVLFLIPKNNPPTLV EEEEEEECCCCCCCC | - | ||
| 233 | Ubiquitination | RVLFLIPKNNPPTLV EEEEEEECCCCCCCC | 23000965 | ||
| 238 | Phosphorylation | IPKNNPPTLVGDFTK EECCCCCCCCCHHHH | 33259812 | ||
| 244 | Phosphorylation | PTLVGDFTKSFKEFI CCCCCHHHHHHHHHH | 22210691 | ||
| 245 | Ubiquitination | TLVGDFTKSFKEFID CCCCHHHHHHHHHHH | 21906983 | ||
| 246 | Phosphorylation | LVGDFTKSFKEFIDA CCCHHHHHHHHHHHH | 27794612 | ||
| 248 | Ubiquitination | GDFTKSFKEFIDACL CHHHHHHHHHHHHHH | 29967540 | ||
| 257 | Ubiquitination | FIDACLNKDPSFRPT HHHHHHCCCCCCCCC | 29967540 | ||
| 260 | Phosphorylation | ACLNKDPSFRPTAKE HHHCCCCCCCCCHHH | 21406692 | ||
| 264 | Phosphorylation | KDPSFRPTAKELLKH CCCCCCCCHHHHHHC | 21406692 | ||
| 266 | Ubiquitination | PSFRPTAKELLKHKF CCCCCCHHHHHHCCE | 29967540 | ||
| 272 | Acetylation | AKELLKHKFIVKNSK HHHHHHCCEEECCCC | 26051181 | ||
| 276 | Acetylation | LKHKFIVKNSKKTSY HHCCEEECCCCCCCH | 25953088 | ||
| 276 | Ubiquitination | LKHKFIVKNSKKTSY HHCCEEECCCCCCCH | 29967540 | ||
| 280 | Malonylation | FIVKNSKKTSYLTEL EEECCCCCCCHHHHH | 26320211 | ||
| 280 | Ubiquitination | FIVKNSKKTSYLTEL EEECCCCCCCHHHHH | 21890473 | ||
| 281 | Phosphorylation | IVKNSKKTSYLTELI EECCCCCCCHHHHHH | 28152594 | ||
| 282 | Phosphorylation | VKNSKKTSYLTELID ECCCCCCCHHHHHHH | 28152594 | ||
| 283 | Phosphorylation | KNSKKTSYLTELIDR CCCCCCCHHHHHHHH | 28152594 | ||
| 285 | Phosphorylation | SKKTSYLTELIDRFK CCCCCHHHHHHHHHH | 28152594 | ||
| 290 | Methylation | YLTELIDRFKRWKAE HHHHHHHHHHHHHHC | 115483897 | ||
| 300 | Phosphorylation | RWKAEGHSDDESDSE HHHHCCCCCCCCCCC | 25159151 | ||
| 304 | Phosphorylation | EGHSDDESDSEGSDS CCCCCCCCCCCCCCC | 28176443 | ||
| 306 | Phosphorylation | HSDDESDSEGSDSES CCCCCCCCCCCCCCC | 26055452 | ||
| 306 | Ubiquitination | HSDDESDSEGSDSES CCCCCCCCCCCCCCC | 29967540 | ||
| 309 | Phosphorylation | DESDSEGSDSESTSR CCCCCCCCCCCCCCC | 25159151 | ||
| 311 | Phosphorylation | SDSEGSDSESTSREN CCCCCCCCCCCCCCC | 28176443 | ||
| 313 | Phosphorylation | SEGSDSESTSRENNT CCCCCCCCCCCCCCC | 28176443 | ||
| 314 | Phosphorylation | EGSDSESTSRENNTH CCCCCCCCCCCCCCC | 30108239 | ||
| 315 | Phosphorylation | GSDSESTSRENNTHP CCCCCCCCCCCCCCC | 24702127 | ||
| 320 | Phosphorylation | STSRENNTHPEWSFT CCCCCCCCCCCCCEE | 22322096 | ||
| 321 | Ubiquitination | TSRENNTHPEWSFTT CCCCCCCCCCCCEEE | 29967540 | ||
| 325 | Phosphorylation | NNTHPEWSFTTVRKK CCCCCCCCEEECCCC | 22167270 | ||
| 327 | Phosphorylation | THPEWSFTTVRKKPD CCCCCCEEECCCCCC | 22322096 | ||
| 328 | Phosphorylation | HPEWSFTTVRKKPDP CCCCCEEECCCCCCH | 22167270 | ||
| 329 | Ubiquitination | PEWSFTTVRKKPDPK CCCCEEECCCCCCHH | 29967540 | ||
| 336 | Ubiquitination | VRKKPDPKKVQNGAE CCCCCCHHHCCCCCH | 29967540 | ||
| 344 | Ubiquitination | KVQNGAEQDLVQTLS HCCCCCHHHHHHHHH | 29967540 | ||
| 354 | Phosphorylation | VQTLSCLSMIITPAF HHHHHHHHHHHCHHH | 22210691 | ||
| 358 | Phosphorylation | SCLSMIITPAFAELK HHHHHHHCHHHHHHH | 22210691 | ||
| 383 | Ubiquitination | QAIEELEKSIAVAEA HHHHHHHHHHHHHHH | 29967540 | ||
| 384 | Phosphorylation | AIEELEKSIAVAEAA HHHHHHHHHHHHHHH | 28555341 | ||
| 398 | Acetylation | ACPGITDKMVKKLIE HCCCCCHHHHHHHHH | 26051181 | ||
| 398 | Ubiquitination | ACPGITDKMVKKLIE HCCCCCHHHHHHHHH | 29967540 | ||
| 401 | Ubiquitination | GITDKMVKKLIEKFQ CCCHHHHHHHHHHHH | - | ||
| 406 | Acetylation | MVKKLIEKFQKCSAD HHHHHHHHHHHCCCC | 25953088 | ||
| 406 | Ubiquitination | MVKKLIEKFQKCSAD HHHHHHHHHHHCCCC | 29967540 | ||
| 415 | Phosphorylation | QKCSADESP------ HHCCCCCCC------ | 28985074 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of STK26_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of STK26_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
