| UniProt ID | STRP1_HUMAN | |
|---|---|---|
| UniProt AC | Q5VSL9 | |
| Protein Name | Striatin-interacting protein 1 | |
| Gene Name | STRIP1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 837 | |
| Subcellular Localization | Cytoplasm . Enriched on the plasma membrane. | |
| Protein Description | Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape.. | |
| Protein Sequence | MEPAVGGPGPLIVNNKQPQPPPPPPPAAAQPPPGAPRAAAGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRSILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAGDSNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRAHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MEPAVGGP -------CCCCCCCC | 22223895 | ||
| 18 | Ubiquitination | LIVNNKQPQPPPPPP EEECCCCCCCCCCCC | 29967540 | ||
| 47 | Ubiquitination | AGLLPGGKAREFNRN HCCCCCCCHHCCCCC | 29967540 | ||
| 57 | Ubiquitination | EFNRNQRKDSEGYSE CCCCCCCCCCCCCCC | 29967540 | ||
| 59 | Phosphorylation | NRNQRKDSEGYSESP CCCCCCCCCCCCCCC | 22167270 | ||
| 62 | Phosphorylation | QRKDSEGYSESPDLE CCCCCCCCCCCCCCC | 22167270 | ||
| 63 | Phosphorylation | RKDSEGYSESPDLEF CCCCCCCCCCCCCCC | 22167270 | ||
| 65 | Phosphorylation | DSEGYSESPDLEFEY CCCCCCCCCCCCCEE | 25159151 | ||
| 72 | Phosphorylation | SPDLEFEYADTDKWA CCCCCCEECCHHHHH | 29978859 | ||
| 75 | Phosphorylation | LEFEYADTDKWAAEL CCCEECCHHHHHHHH | 21406692 | ||
| 99 | Ubiquitination | PEFLMNRKCFEEDFR CHHHHCCHHHHCCCE | - | ||
| 113 | Ubiquitination | RIHVTDKKWTELDTN EEEECCCCCEECCCH | 29967540 | ||
| 214 | Phosphorylation | AISLADSTDLRVLLN CCCCCCCCHHHHHHH | 25332170 | ||
| 230 | Ubiquitination | MYLIVETVHQECEGD HHHHHHHHHHHCCCC | 27667366 | ||
| 240 | Phosphorylation | ECEGDKAEWRTMRQT HCCCCHHHHHHHHHH | 32645325 | ||
| 244 | Phosphorylation | DKAEWRTMRQTFRAE CHHHHHHHHHHHHHH | 33259812 | ||
| 265 | Ubiquitination | NNEPFAIMLFGMVTK CCCCCHHHHHHHHHH | 29967540 | ||
| 271 | Phosphorylation | IMLFGMVTKFCSGHA HHHHHHHHHHHCCCC | - | ||
| 275 | Phosphorylation | GMVTKFCSGHAPHFP HHHHHHHCCCCCCCC | 29083192 | ||
| 313 | Phosphorylation | SMKAEKRSILGLPPL HHHHHHHCCCCCCCC | 20068231 | ||
| 324 | Phosphorylation | LPPLPEDSIKVIRNM CCCCCHHHHHHHHHH | 20068231 | ||
| 325 | Ubiquitination | PPLPEDSIKVIRNMR CCCCHHHHHHHHHHH | 32015554 | ||
| 326 | Ubiquitination | PLPEDSIKVIRNMRA CCCHHHHHHHHHHHH | - | ||
| 335 | Phosphorylation | IRNMRAASPPASASD HHHHHHCCCCCCHHH | 19664994 | ||
| 339 | Phosphorylation | RAASPPASASDLIEQ HHCCCCCCHHHHHHH | 30278072 | ||
| 341 | Phosphorylation | ASPPASASDLIEQQQ CCCCCCHHHHHHHHH | 29209046 | ||
| 360 | Ubiquitination | REHKALIKQDNLDAF HHHHHHHHHCCHHHH | 29967540 | ||
| 373 | Ubiquitination | AFNERDPYKADDSRE HHHCCCCCCCCCCHH | 29967540 | ||
| 390 | Phosphorylation | EENDDDNSLEGETFP HHCCCCCCCCCCEEC | 26657352 | ||
| 416 | Ubiquitination | QHPQTDRLTCPKGLP CCCCCCCCCCCCCCC | 27667366 | ||
| 420 | Ubiquitination | TDRLTCPKGLPWAPK CCCCCCCCCCCCCCC | 32015554 | ||
| 436 | Ubiquitination | REKDIEMFLESSRSK CHHHHHHHHHHCCCC | 21890473 | ||
| 441 | Ubiquitination | EMFLESSRSKFIGYT HHHHHHCCCCCCEEE | 32015554 | ||
| 468 | Ubiquitination | RPIHESIKTLKQHKY CCHHHHHHHHHHCCC | 29967540 | ||
| 489 | Phosphorylation | QAQMEEEYLRSPLSG HHHHHHHHHHCCCCC | - | ||
| 492 | Phosphorylation | MEEEYLRSPLSGGEE HHHHHHHCCCCCCHH | - | ||
| 522 | Ubiquitination | PSLPQYMIALLKILL CCHHHHHHHHHHHHH | 22817900 | ||
| 536 | Malonylation | LAAAPTSKAKTDSIN HHHCCCCCCCCCCCH | 26320211 | ||
| 536 | Ubiquitination | LAAAPTSKAKTDSIN HHHCCCCCCCCCCCH | 32015554 | ||
| 538 | Ubiquitination | AAPTSKAKTDSINIL HCCCCCCCCCCCHHH | - | ||
| 560 | Phosphorylation | MPTTVLQSMKLGVDV CCHHHHHHCCCCCCC | 19060867 | ||
| 595 | Phosphorylation | HFKLNHVYQFEYMAQ HHCCCCCHHHHHHHH | - | ||
| 599 | Phosphorylation | NHVYQFEYMAQHLVF CCCHHHHHHHHHHHH | - | ||
| 604 | Ubiquitination | FEYMAQHLVFANCIP HHHHHHHHHHHHHHH | 32015554 | ||
| 627 | Ubiquitination | NIMSYITAKNSISVL CHHHHHHHCCCCEEC | 27667366 | ||
| 646 | Ubiquitination | CVVHELPELTAESLE CEECCCCCCCHHHHH | 27667366 | ||
| 647 | Ubiquitination | VVHELPELTAESLEA EECCCCCCCHHHHHC | 21890473 | ||
| 666 | Ubiquitination | QFCWRNLFSCINLLR HHHHHHHHHHHHHHH | 21890473 | ||
| 677 | Acetylation | NLLRILNKLTKWKHS HHHHHHHHHHCCCCC | 18585881 | ||
| 699 | Ubiquitination | FKSAPILKRALKVKQ ECCHHHHHHHHHHHH | 32015554 | ||
| 712 | Phosphorylation | KQAMMQLYVLKLLKV HHHHHHHHHHHHHHH | - | ||
| 722 | Ubiquitination | KLLKVQTKYLGRQWR HHHHHHHHHHCHHHH | 27667366 | ||
| 722 | Methylation | KLLKVQTKYLGRQWR HHHHHHHHHHCHHHH | 23644510 | ||
| 733 | Ubiquitination | RQWRKSNMKTMSAIY HHHHHHCHHHHHHHH | 22817900 | ||
| 733 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 740 | Phosphorylation | MKTMSAIYQKVRHRL HHHHHHHHHHHHHHC | 22817900 | ||
| 742 | Ubiquitination | TMSAIYQKVRHRLND HHHHHHHHHHHHCCC | 21890473 | ||
| 752 | Ubiquitination | HRLNDDWAYGNDLDA HHCCCCCCCCCCCCC | 22817900 | ||
| 788 | Phosphorylation | RRYDRAHSNPDFLPV HHHHCCCCCCCCCCH | 28450419 | ||
| 828 | Ubiquitination | LEREVFSKPISWEEL HHHHHHCCCCCHHHH | 22817900 | ||
| 828 (in isoform 1) | Ubiquitination | - | 21906983 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of STRP1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of STRP1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of STRP1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| 2AAA_HUMAN | PPP2R1A | physical | 18782753 | |
| PP2AA_HUMAN | PPP2CA | physical | 18782753 | |
| STRN_HUMAN | STRN | physical | 18782753 | |
| STRN3_HUMAN | STRN3 | physical | 18782753 | |
| STK26_HUMAN | STK26 | physical | 18782753 | |
| STRN4_HUMAN | STRN4 | physical | 18782753 | |
| PHOCN_HUMAN | MOB4 | physical | 18782753 | |
| PDC10_HUMAN | PDCD10 | physical | 18782753 | |
| CT2NL_HUMAN | CTTNBP2NL | physical | 18782753 | |
| SIKE1_HUMAN | SIKE1 | physical | 18782753 | |
| STRP2_HUMAN | STRIP2 | physical | 18782753 | |
| SLMAP_HUMAN | SLMAP | physical | 18782753 | |
| FGOP2_HUMAN | FGFR1OP2 | physical | 18782753 | |
| STRN4_HUMAN | STRN4 | physical | 22939629 | |
| POP1_HUMAN | POP1 | physical | 22939629 | |
| GT251_HUMAN | COLGALT1 | physical | 22939629 | |
| KATL2_HUMAN | KATNAL2 | physical | 22939629 | |
| SPTN1_HUMAN | SPTAN1 | physical | 22939629 | |
| FUBP2_HUMAN | KHSRP | physical | 22939629 | |
| NU214_HUMAN | NUP214 | physical | 22939629 | |
| RBM4_HUMAN | RBM4 | physical | 22939629 | |
| SLMAP_HUMAN | SLMAP | physical | 26344197 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
