dbPTM

GPTC8_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GPTC8_HUMAN
UniProt AC	Q9UKJ3
Protein Name	G patch domain-containing protein 8
Gene Name	GPATCH8
Organism	Homo sapiens (Human).
Sequence Length	1502
Subcellular Localization
Protein Description
Protein Sequence	MADRFSRFNEDRDFQGNHFDQYEEGHLEIEQASLDKPIESDNIGHRLLQKHGWKLGQGLGKSLQGRTDPIPIVVKYDVMGMGRMEMELDYAEDATERRRVLEVEKEDTEELRQKYKDYVDKEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFARNVSSRSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESATNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQGISFGIKNNLGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDSSSQPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPASAALAPATPALQPIHIQQPATASATSITTVQHAILQHHAAAAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLASHPIHIIPASAIHPGPFTFHPVPHAALYPTLLAPRPAAAAATALHLHPLLHPIFSGQDLQHPPSHGT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Phosphorylation	QGNHFDQYEEGHLEI CCCCCHHHHHCCEEE	20.14	28796482
27	Ubiquitination	DQYEEGHLEIEQASL HHHHHCCEEEEECCC	11.88	24816145
50	Ubiquitination	IGHRLLQKHGWKLGQ HHHHHHHHHCCCCCC	44.02	29967540
54	Ubiquitination	LLQKHGWKLGQGLGK HHHHHCCCCCCCCHH	47.54	29967540
61	Acetylation	KLGQGLGKSLQGRTD CCCCCCHHHHCCCCC	53.70	25953088
62	Phosphorylation	LGQGLGKSLQGRTDP CCCCCHHHHCCCCCC	24.91	25159151
76	Phosphorylation	PIPIVVKYDVMGMGR CCCEEEEEECCCCCC	11.36	20068231
80	Ubiquitination	VVKYDVMGMGRMEME EEEEECCCCCCEEEE	18.42	24816145
86	Phosphorylation	MGMGRMEMELDYAED CCCCCEEEEHHHCCH	4.53	17525332
90	Phosphorylation	RMEMELDYAEDATER CEEEEHHHCCHHHHH	25.23	24043423
95	Phosphorylation	LDYAEDATERRRVLE HHHCCHHHHHHHHEE	42.20	21082442
105	Acetylation	RRVLEVEKEDTEELR HHHEEECHHCHHHHH	67.09	26051181
105	Ubiquitination	RRVLEVEKEDTEELR HHHEEECHHCHHHHH	67.09	24816145
118	Phosphorylation	LRQKYKDYVDKEKAI HHHHHHHHHHHHHHH	13.34	-
137	Phosphorylation	EDLRANFYCELCDKQ HHHHHHHHHHHCHHH	5.70	25884760
179	Phosphorylation	REFARNVSSRSRKDE HHHHHHHHHHCHHCH	24.47	23898821
180	Phosphorylation	EFARNVSSRSRKDEK HHHHHHHHHCHHCHH	29.96	23898821
188	Methylation	RSRKDEKKQEKALRR HCHHCHHHHHHHHHH	62.74	-
237	Phosphorylation	DDKDESATNSGTGAT CCCCCCCCCCCCCCC	38.91	15302935
242	Phosphorylation	SATNSGTGATASCGL CCCCCCCCCCCCCCC	25.18	15302935
293	Phosphorylation	GIKNNLGTPLQKLGV CCCCCCCCCHHHHCC	24.80	25159151
298	Ubiquitination	LGTPLQKLGVSFSFA CCCCHHHHCCCEEHH	5.44	29967540
301	Phosphorylation	PLQKLGVSFSFAKKA CHHHHCCCEEHHHCC	17.24	28348404
303	Phosphorylation	QKLGVSFSFAKKAPV HHHCCCEEHHHCCCC	19.45	28555341
307	Acetylation	VSFSFAKKAPVKLES CCEEHHHCCCCCHHH	55.27	25953088
311	Sumoylation	FAKKAPVKLESIASV HHHCCCCCHHHHHHH	45.54	28112733
314	Phosphorylation	KAPVKLESIASVFKD CCCCCHHHHHHHHHH	33.61	28555341
317	Phosphorylation	VKLESIASVFKDHAE CCHHHHHHHHHHHHC	26.81	28555341
327	Phosphorylation	KDHAEEGTSEDGTKP HHHHCCCCCCCCCCC	32.02	25850435
328	Phosphorylation	DHAEEGTSEDGTKPD HHHCCCCCCCCCCCC	44.54	29496963
332	Phosphorylation	EGTSEDGTKPDEKSS CCCCCCCCCCCCCCC	52.29	28985074
349	Phosphorylation	GLQKVGDSDGSSNLD CHHHHCCCCCCCCCC	37.63	28985074
351	Ubiquitination	QKVGDSDGSSNLDGK HHHCCCCCCCCCCCC	36.60	29967540
352	Phosphorylation	KVGDSDGSSNLDGKK HHCCCCCCCCCCCCC	22.50	23401153
353	Phosphorylation	VGDSDGSSNLDGKKE HCCCCCCCCCCCCCC	47.11	25627689
369	Phosphorylation	EDPQDGGSLASTLSK CCCCCCHHHHHHHHH	26.71	23312004
372	Phosphorylation	QDGGSLASTLSKLKR CCCHHHHHHHHHHHH	34.86	23312004
373	Phosphorylation	DGGSLASTLSKLKRM CCHHHHHHHHHHHHH	29.46	20068231
375	Phosphorylation	GSLASTLSKLKRMKR HHHHHHHHHHHHHHH	35.71	23312004
376	Ubiquitination	SLASTLSKLKRMKRE HHHHHHHHHHHHHHH	62.23	29967540
394	Phosphorylation	GATEPEYYHYIPPAH CCCCCCCCCCCCHHH	6.10	17287340
438	Phosphorylation	APESKKGSSPKPKSC CCCCCCCCCCCCHHH	52.96	22798277
439	Phosphorylation	PESKKGSSPKPKSCI CCCCCCCCCCCHHHH	45.68	24706070
444	Phosphorylation	GSSPKPKSCIKAAAS CCCCCCHHHHHHHHH	29.60	-
447	Acetylation	PKPKSCIKAAASQGA CCCHHHHHHHHHCCC	35.98	25953088
451	Phosphorylation	SCIKAAASQGAEKTV HHHHHHHHCCCCHHH	25.15	-
456	Acetylation	AASQGAEKTVSEVSE HHHCCCCHHHHHHHH	54.41	25953088
457	Phosphorylation	ASQGAEKTVSEVSEQ HHCCCCHHHHHHHHC	22.29	-
459	Phosphorylation	QGAEKTVSEVSEQPK CCCCHHHHHHHHCCC	37.20	21712546
468	Phosphorylation	VSEQPKETSMTEPSE HHHCCCCCCCCCCCC	29.89	27134283
469	Phosphorylation	SEQPKETSMTEPSEP HHCCCCCCCCCCCCC	25.46	21815630
471	Phosphorylation	QPKETSMTEPSEPGS CCCCCCCCCCCCCCC	44.50	23532336
474	Phosphorylation	ETSMTEPSEPGSKAE CCCCCCCCCCCCHHH	50.63	30576142
478	Phosphorylation	TEPSEPGSKAEAKKA CCCCCCCCHHHHHHH	39.13	23532336
479	Acetylation	EPSEPGSKAEAKKAL CCCCCCCHHHHHHHH	57.04	26051181
491	Phosphorylation	KALGGDVSDQSLESH HHHCCCCCHHHHHHH	34.37	20873877
494	Phosphorylation	GGDVSDQSLESHSQK CCCCCHHHHHHHHHH	38.81	20873877
497	Phosphorylation	VSDQSLESHSQKVSE CCHHHHHHHHHHCCH	33.46	23186163
498	Phosphorylation	SDQSLESHSQKVSET CHHHHHHHHHHCCHH	25.52	16083285
499	Phosphorylation	DQSLESHSQKVSETQ HHHHHHHHHHCCHHH	40.76	17525332
501	Phosphorylation	SLESHSQKVSETQMC HHHHHHHHCCHHHHH	51.23	16083285
503	Phosphorylation	ESHSQKVSETQMCES HHHHHHCCHHHHHCC	41.80	20068231
505	Phosphorylation	HSQKVSETQMCESNS HHHHCCHHHHHCCCC	17.69	20068231
510	Phosphorylation	SETQMCESNSSKETS CHHHHHCCCCCCCCC	36.76	20068231
512	Phosphorylation	TQMCESNSSKETSLA HHHHCCCCCCCCCCC	52.66	20068231
513	Phosphorylation	QMCESNSSKETSLAT HHHCCCCCCCCCCCC	38.47	20068231
514	Acetylation	MCESNSSKETSLATP HHCCCCCCCCCCCCC	65.90	26051181
516	Phosphorylation	ESNSSKETSLATPAG CCCCCCCCCCCCCCC	32.55	23403867
517	Phosphorylation	SNSSKETSLATPAGK CCCCCCCCCCCCCCC	19.66	20068231
520	Phosphorylation	SKETSLATPAGKESQ CCCCCCCCCCCCCCC	20.97	21815630
526	Phosphorylation	ATPAGKESQEGPKHP CCCCCCCCCCCCCCC	36.70	23403867
542	Phosphorylation	GPFFPVLSKDESTAL CCCCCCCCCCHHHCC	37.99	27251275
573	Phosphorylation	SYSCNPLYFDFKLSR EEECCCEEEEEEECC	11.45	-
577	Sumoylation	NPLYFDFKLSRNKDA CCEEEEEEECCCCCC	47.61	28112733
596	Phosphorylation	TEKPKDIGSSSKDHL CCCCCCCCCCCHHHH	31.44	17081983
597	Phosphorylation	EKPKDIGSSSKDHLQ CCCCCCCCCCHHHHC	31.60	21712546
599	Phosphorylation	PKDIGSSSKDHLQGL CCCCCCCCHHHHCCC	43.74	21712546
600	Acetylation	KDIGSSSKDHLQGLD CCCCCCCHHHHCCCC	51.63	26051181
601	Phosphorylation	DIGSSSKDHLQGLDP CCCCCCHHHHCCCCC	50.07	17081983
620	Phosphorylation	KSKEVGGEKIVRSSG CCCCCCCEEEEECCC	33.41	17081983
621	Acetylation	SKEVGGEKIVRSSGG CCCCCCEEEEECCCC	50.18	25953088
622	Phosphorylation	KEVGGEKIVRSSGGR CCCCCEEEEECCCCC	2.43	16565220
630	Sulfoxidation	VRSSGGRMDAPASGS EECCCCCCCCCCCCC	6.11	21406390
635	Phosphorylation	GRMDAPASGSACSGL CCCCCCCCCCCCCCC	32.02	27251789
637	Phosphorylation	MDAPASGSACSGLNK CCCCCCCCCCCCCCC	24.49	25159151
640	Phosphorylation	PASGSACSGLNKQEP CCCCCCCCCCCCCCC	46.13	23927012
644	Acetylation	SACSGLNKQEPGGSH CCCCCCCCCCCCCCC	62.17	26051181
650	Phosphorylation	NKQEPGGSHGSETED CCCCCCCCCCCCCCC	30.50	29255136
653	Phosphorylation	EPGGSHGSETEDTGR CCCCCCCCCCCCCCC	35.60	29255136
655	Phosphorylation	GGSHGSETEDTGRSL CCCCCCCCCCCCCCC	40.64	29255136
658	Phosphorylation	HGSETEDTGRSLPSK CCCCCCCCCCCCCCH	28.41	22167270
661	Phosphorylation	ETEDTGRSLPSKKER CCCCCCCCCCCHHHC	46.07	26074081
662	Phosphorylation	TEDTGRSLPSKKERS CCCCCCCCCCHHHCC	5.52	32142685
664	Phosphorylation	DTGRSLPSKKERSGK CCCCCCCCHHHCCCC	62.75	24719451
694	Phosphorylation	HKRKHKADTEEKSSK HHHHHHHHHHHHHHH	60.50	17081983
715	Phosphorylation	SKKRKKRKRKKNKSS HHHHHHHHHHHCCCC	76.95	32142685
721	Phosphorylation	RKRKKNKSSAPADSE HHHHHCCCCCCCCCC	40.92	23403867
722	Phosphorylation	KRKKNKSSAPADSER HHHHCCCCCCCCCCC	39.62	23403867
727	Phosphorylation	KSSAPADSERGPKPE CCCCCCCCCCCCCCC	31.16	23401153
738	Phosphorylation	PKPEPPGSGSPAPPR CCCCCCCCCCCCCCH	41.70	29255136
740	Phosphorylation	PEPPGSGSPAPPRRR CCCCCCCCCCCCHHH	21.42	29255136
754	Phosphorylation	RRRAQDDSQRRSLPA HCCCCCHHHHCCCCH	33.60	28102081
758	Phosphorylation	QDDSQRRSLPAEEGS CCHHHHCCCCHHHCC	40.68	23401153
765	Phosphorylation	SLPAEEGSSGKKDEG CCCHHHCCCCCCCCC	38.92	21815630
766	Phosphorylation	LPAEEGSSGKKDEGG CCHHHCCCCCCCCCC	66.54	23927012
776	Phosphorylation	KDEGGGGSSSQDHGG CCCCCCCCCCCCCCC	30.05	28111955
777	Phosphorylation	DEGGGGSSSQDHGGR CCCCCCCCCCCCCCC	34.98	28111955
778	Phosphorylation	EGGGGSSSQDHGGRK CCCCCCCCCCCCCCC	41.13	28111955
793	Phosphorylation	HKGELPPSSCQRRAG CCCCCCCHHHHHHCC	41.63	25627689
794	Phosphorylation	KGELPPSSCQRRAGT CCCCCCHHHHHHCCC	21.75	25627689
804	Phosphorylation	RRAGTKRSSRSSHRS HHCCCCCCCCCCCCC	31.49	20068231
805	Phosphorylation	RAGTKRSSRSSHRSQ HCCCCCCCCCCCCCC	39.97	20068231
807	Phosphorylation	GTKRSSRSSHRSQPS CCCCCCCCCCCCCCC	32.23	20068231
808	Phosphorylation	TKRSSRSSHRSQPSS CCCCCCCCCCCCCCC	23.08	28634120
811	Phosphorylation	SSRSSHRSQPSSGDE CCCCCCCCCCCCCCC	40.81	28634120
814	Phosphorylation	SSHRSQPSSGDEDSD CCCCCCCCCCCCCCC	39.04	20363803
815	Phosphorylation	SHRSQPSSGDEDSDD CCCCCCCCCCCCCCC	57.87	20363803
820	Phosphorylation	PSSGDEDSDDASSHR CCCCCCCCCCHHHHH	35.03	20363803
824	Phosphorylation	DEDSDDASSHRLHQK CCCCCCHHHHHHHCC	33.40	30242111
825	Phosphorylation	EDSDDASSHRLHQKS CCCCCHHHHHHHCCC	17.85	28634120
832	Phosphorylation	SHRLHQKSPSQYSEE HHHHHCCCHHHCCHH	24.18	28290473
834	Phosphorylation	RLHQKSPSQYSEEEE HHHCCCHHHCCHHHH	49.17	23927012
836	Phosphorylation	HQKSPSQYSEEEEEE HCCCHHHCCHHHHHC	23.53	23927012
837	Phosphorylation	QKSPSQYSEEEEEED CCCHHHCCHHHHHCC	30.78	23927012
845	Phosphorylation	EEEEEEDSGSEHSRS HHHHHCCCCCCCCHH	47.72	23927012
845	Ubiquitination	EEEEEEDSGSEHSRS HHHHHCCCCCCCCHH	47.72	24816145
847	Phosphorylation	EEEEDSGSEHSRSRS HHHCCCCCCCCHHHC	35.77	23927012
850	Phosphorylation	EDSGSEHSRSRSRSG CCCCCCCCHHHCCCC	28.09	23927012
861	Phosphorylation	SRSGRRHSSHRSSRR CCCCCCCCCCCCCCC	26.48	-
862	Phosphorylation	RSGRRHSSHRSSRRS CCCCCCCCCCCCCCC	19.45	-
866	Phosphorylation	RHSSHRSSRRSYSSS CCCCCCCCCCCCCCC	31.50	30576142
869	Phosphorylation	SHRSSRRSYSSSSDA CCCCCCCCCCCCCCC	28.40	27486199
870	Phosphorylation	HRSSRRSYSSSSDAS CCCCCCCCCCCCCCC	15.68	27486199
871	Phosphorylation	RSSRRSYSSSSDASS CCCCCCCCCCCCCCC	25.62	27486199
872	Phosphorylation	SSRRSYSSSSDASSD CCCCCCCCCCCCCCC	26.15	27486199
873	Phosphorylation	SRRSYSSSSDASSDQ CCCCCCCCCCCCCCC	26.71	27486199
874	Phosphorylation	RRSYSSSSDASSDQS CCCCCCCCCCCCCCH	38.86	27486199
877	Phosphorylation	YSSSSDASSDQSCYS CCCCCCCCCCCHHHH	39.16	27486199
878	Phosphorylation	SSSSDASSDQSCYSR CCCCCCCCCCHHHHC	41.19	27486199
881	Phosphorylation	SDASSDQSCYSRQRS CCCCCCCHHHHCCCC	21.73	27486199
883	Phosphorylation	ASSDQSCYSRQRSYS CCCCCHHHHCCCCCC	16.49	27486199
884	Phosphorylation	SSDQSCYSRQRSYSD CCCCHHHHCCCCCCC	26.68	27486199
888	Phosphorylation	SCYSRQRSYSDDSYS HHHHCCCCCCCCCCC	22.20	23401153
889	Phosphorylation	CYSRQRSYSDDSYSD HHHCCCCCCCCCCCC	20.50	23401153
890	Phosphorylation	YSRQRSYSDDSYSDY HHCCCCCCCCCCCCC	35.87	23401153
893	Phosphorylation	QRSYSDDSYSDYSDR CCCCCCCCCCCCCHH	31.37	23401153
894	Phosphorylation	RSYSDDSYSDYSDRS CCCCCCCCCCCCHHH	16.74	23401153
895	Phosphorylation	SYSDDSYSDYSDRSR CCCCCCCCCCCHHHH	33.74	23927012
897	Phosphorylation	SDDSYSDYSDRSRRH CCCCCCCCCHHHHHH	13.41	23401153
898	Phosphorylation	DDSYSDYSDRSRRHS CCCCCCCCHHHHHHC	31.38	25849741
901	Phosphorylation	YSDYSDRSRRHSKRS CCCCCHHHHHHCCCC	38.36	30576142
903	Phosphorylation	DYSDRSRRHSKRSHD CCCHHHHHHCCCCCC	39.41	32645325
905	Phosphorylation	SDRSRRHSKRSHDSD CHHHHHHCCCCCCCC	28.14	30576142
908	O-linked_Glycosylation	SRRHSKRSHDSDDSD HHHHCCCCCCCCCCC	35.07	30379171
908	Phosphorylation	SRRHSKRSHDSDDSD HHHHCCCCCCCCCCC	35.07	25159151
911	Phosphorylation	HSKRSHDSDDSDYAS HCCCCCCCCCCCHHH	37.58	25159151
914	Phosphorylation	RSHDSDDSDYASSKH CCCCCCCCCHHHHHH	37.20	25159151
916	Phosphorylation	HDSDDSDYASSKHRS CCCCCCCHHHHHHHH	16.60	30576142
918	Phosphorylation	SDDSDYASSKHRSKR CCCCCHHHHHHHHHC	33.42	23663014
919	Phosphorylation	DDSDYASSKHRSKRH CCCCHHHHHHHHHCC	25.06	30576142
923	Phosphorylation	YASSKHRSKRHKYSS HHHHHHHHHCCCCCC	33.49	-
930	Phosphorylation	SKRHKYSSSDDDYSL HHCCCCCCCCCCCCC	34.40	23927012
931	Phosphorylation	KRHKYSSSDDDYSLS HCCCCCCCCCCCCCC	38.83	23927012
935	Phosphorylation	YSSSDDDYSLSCSQS CCCCCCCCCCCCHHC	20.64	23927012
936	Phosphorylation	SSSDDDYSLSCSQSR CCCCCCCCCCCHHCC	22.32	23927012
938	Phosphorylation	SDDDYSLSCSQSRSR CCCCCCCCCHHCCCC	13.04	23927012
940	Phosphorylation	DDYSLSCSQSRSRSR CCCCCCCHHCCCCCC	28.02	23927012
942	Phosphorylation	YSLSCSQSRSRSRSH CCCCCHHCCCCCCCH	18.87	23927012
944	Phosphorylation	LSCSQSRSRSRSHTR CCCHHCCCCCCCHHH	39.59	30576142
950	Phosphorylation	RSRSRSHTRERSRSR CCCCCCHHHHHHHHH	35.16	28634120
954	Phosphorylation	RSHTRERSRSRGRSR CCHHHHHHHHHCCCC	29.83	23312004
956	Phosphorylation	HTRERSRSRGRSRSS HHHHHHHHHCCCCCH	40.09	20068231
957	Phosphorylation	TRERSRSRGRSRSSS HHHHHHHHCCCCCHH	43.35	32142685
960	Phosphorylation	RSRSRGRSRSSSCSR HHHHHCCCCCHHHCC	39.06	20068231
962	Phosphorylation	RSRGRSRSSSCSRSR HHHCCCCCHHHCCCH	28.05	26546556
964	Phosphorylation	RGRSRSSSCSRSRSK HCCCCCHHHCCCHHH	19.84	26546556
966	Phosphorylation	RSRSSSCSRSRSKRR CCCCHHHCCCHHHCC	34.93	26546556
974	Phosphorylation	RSRSKRRSRSTTAHS CCHHHCCCCCCCHHH	34.32	22617229
976	Phosphorylation	RSKRRSRSTTAHSWQ HHHCCCCCCCHHHHH	31.21	30266825
977	Phosphorylation	SKRRSRSTTAHSWQR HHCCCCCCCHHHHHH	27.22	30266825
978	Phosphorylation	KRRSRSTTAHSWQRS HCCCCCCCHHHHHHH	24.50	23401153
981	Phosphorylation	SRSTTAHSWQRSRSY CCCCCHHHHHHHHCC	23.57	30266825
981	Ubiquitination	SRSTTAHSWQRSRSY CCCCCHHHHHHHHCC	23.57	24816145
985	Phosphorylation	TAHSWQRSRSYSRDR CHHHHHHHHCCCCCC	15.52	20068231
987	Phosphorylation	HSWQRSRSYSRDRSR HHHHHHHCCCCCCCC	28.80	20068231
988	Phosphorylation	SWQRSRSYSRDRSRS HHHHHHCCCCCCCCC	13.45	17081983
989	Phosphorylation	WQRSRSYSRDRSRST HHHHHCCCCCCCCCC	29.02	21406692
993	Phosphorylation	RSYSRDRSRSTRSPS HCCCCCCCCCCCCCC	34.57	20068231
995	O-linked_Glycosylation	YSRDRSRSTRSPSQR CCCCCCCCCCCCCCC	29.44	30379171
995	Phosphorylation	YSRDRSRSTRSPSQR CCCCCCCCCCCCCCC	29.44	28176443
996	Phosphorylation	SRDRSRSTRSPSQRS CCCCCCCCCCCCCCC	33.77	28176443
998	Phosphorylation	DRSRSTRSPSQRSGS CCCCCCCCCCCCCCC	29.05	25849741
1000	Phosphorylation	SRSTRSPSQRSGSRK CCCCCCCCCCCCCCC	39.20	28176443
1009	Phosphorylation	RSGSRKRSWGHESPE CCCCCCCCCCCCCHH	40.21	22167270
1010	Phosphorylation	SGSRKRSWGHESPEE CCCCCCCCCCCCHHH	19.05	32142685
1010	Ubiquitination	SGSRKRSWGHESPEE CCCCCCCCCCCCHHH	19.05	24816145
1014	Phosphorylation	KRSWGHESPEERHSG CCCCCCCCHHHHHCC	31.75	22167270
1020	Phosphorylation	ESPEERHSGRRDFIR CCHHHHHCCCHHHHH	39.97	20873877
1029	Phosphorylation	RRDFIRSKIYRSQSP CHHHHHHHHHHCCCC	33.63	32142685
1031	Phosphorylation	DFIRSKIYRSQSPHY HHHHHHHHHCCCCCC	14.14	23927012
1033	Phosphorylation	IRSKIYRSQSPHYFR HHHHHHHCCCCCCCC	20.31	22167270
1034	Ubiquitination	RSKIYRSQSPHYFRS HHHHHHCCCCCCCCC	52.57	24816145
1035	Phosphorylation	SKIYRSQSPHYFRSG HHHHHCCCCCCCCCC	18.19	22167270
1038	Phosphorylation	YRSQSPHYFRSGRGE HHCCCCCCCCCCCCC	12.22	22167270
1058	Phosphorylation	DDGRGDDSKATGPPS CCCCCCCCCCCCCCC	29.00	24719451
1059	Ubiquitination	DGRGDDSKATGPPSQ CCCCCCCCCCCCCCC	57.89	24816145
1061	Phosphorylation	RGDDSKATGPPSQNS CCCCCCCCCCCCCCC	54.69	23663014
1064	Acetylation	DSKATGPPSQNSNIG CCCCCCCCCCCCCCC	50.30	19608861
1065	Phosphorylation	SKATGPPSQNSNIGT CCCCCCCCCCCCCCC	45.16	25159151
1068	Phosphorylation	TGPPSQNSNIGTGRG CCCCCCCCCCCCCCC	23.37	23927012
1072	Phosphorylation	SQNSNIGTGRGSEGD CCCCCCCCCCCCCCC	21.65	25159151
1076	Phosphorylation	NIGTGRGSEGDCSPE CCCCCCCCCCCCCHH	36.73	22167270
1081	Phosphorylation	RGSEGDCSPEDKNSV CCCCCCCCHHHCCCH	35.74	29255136
1082	Phosphorylation	GSEGDCSPEDKNSVT CCCCCCCHHHCCCHH	61.20	32142685
1085	Acetylation	GDCSPEDKNSVTAKL CCCCHHHCCCHHHHH	49.84	26051181
1087	Phosphorylation	CSPEDKNSVTAKLLL CCHHHCCCHHHHHHH	26.95	22167270
1088	Ubiquitination	SPEDKNSVTAKLLLE CHHHCCCHHHHHHHH	9.37	24816145
1089	Phosphorylation	PEDKNSVTAKLLLEK HHHCCCHHHHHHHHH	20.21	22167270
1096	Acetylation	TAKLLLEKIQSRKVE HHHHHHHHHHHCCCC	46.12	25953088
1105	Sumoylation	QSRKVERKPSVSEEV HHCCCCCCCCCCHHH	28.30	28112733
1105	Ubiquitination	QSRKVERKPSVSEEV HHCCCCCCCCCCHHH	28.30	22817900
1107	Phosphorylation	RKVERKPSVSEEVQA CCCCCCCCCCHHHHC	41.11	29255136
1108	Ubiquitination	KVERKPSVSEEVQAT CCCCCCCCCHHHHCC	13.00	21890473
1109	Phosphorylation	VERKPSVSEEVQATP CCCCCCCCHHHHCCC	32.17	23401153
1115	Phosphorylation	VSEEVQATPNKAGPK CCHHHHCCCCCCCCC	15.42	29255136
1117	Acetylation	EEVQATPNKAGPKLK HHHHCCCCCCCCCCC	42.32	19608861
1118	Acetylation	EVQATPNKAGPKLKD HHHCCCCCCCCCCCC	56.79	25953088
1124	Ubiquitination	NKAGPKLKDPPQGYF CCCCCCCCCCCCCCC	74.45	21890473
1127	Ubiquitination	GPKLKDPPQGYFGPK CCCCCCCCCCCCCCC	50.81	22817900
1130	Phosphorylation	LKDPPQGYFGPKLPP CCCCCCCCCCCCCCH	10.50	-
1138	Phosphorylation	FGPKLPPSLGNKPVL CCCCCCHHHCCCCCH	47.14	28555341
1142	Acetylation	LPPSLGNKPVLPLIG CCHHHCCCCCHHHCC	34.40	23954790
1150	Acetylation	PVLPLIGKLPATRKP CCHHHCCCCCCCCCC	44.28	25953088
1154	Phosphorylation	LIGKLPATRKPNKKC HCCCCCCCCCCCCCH	36.97	29457462
1164	Phosphorylation	PNKKCEESGLERGEE CCCCHHHHCCCCCHH	26.78	26074081
1175	Phosphorylation	RGEEQEQSETEEGPP CCHHHHCCCCCCCCC	45.81	23663014
1177	Phosphorylation	EEQEQSETEEGPPGS HHHHCCCCCCCCCCC	44.58	23663014
1184	Phosphorylation	TEEGPPGSSDALFGH CCCCCCCCCHHHCCC	30.71	23663014
1185	Phosphorylation	EEGPPGSSDALFGHQ CCCCCCCCHHHCCCC	32.58	23663014
1195	Phosphorylation	LFGHQFPSEETTGPL HCCCCCCCCCCCCCC	49.72	23663014
1198	Phosphorylation	HQFPSEETTGPLLDP CCCCCCCCCCCCCCC	32.76	23663014
1199	Phosphorylation	QFPSEETTGPLLDPP CCCCCCCCCCCCCCC	39.83	23663014
1210	Phosphorylation	LDPPPEESKSGEATA CCCCCCCCCCCCCCC	30.38	20873877
1226	Phosphorylation	HPVAPLGTPAHSDCY CCCCCCCCCCCCCCC	25.61	26074081
1230	Phosphorylation	PLGTPAHSDCYPGDP CCCCCCCCCCCCCCC	31.33	26074081
1241	Ubiquitination	PGDPTISHNYLPDPS CCCCCCCCCCCCCCC	24.09	22817900
1244	Ubiquitination	PTISHNYLPDPSDGD CCCCCCCCCCCCCCC	4.75	21890473
1244 (in isoform 2)	Ubiquitination	-	4.75	21890473
1260	Phosphorylation	LESLDSSSQPGPVES HHHCCCCCCCCCCCH	44.33	-
1260	Ubiquitination	LESLDSSSQPGPVES HHHCCCCCCCCCCCH	44.33	21890473
1260 (in isoform 2)	Ubiquitination	-	44.33	21890473
1263	Ubiquitination	LDSSSQPGPVESSLL CCCCCCCCCCCHHHC	31.11	22817900
1270	Ubiquitination	GPVESSLLPIAPDLE CCCCHHHCCCCCCHH	2.89	22817900
1273	Ubiquitination	ESSLLPIAPDLEHFP CHHHCCCCCCHHCCC	6.93	21890473
1289	Ubiquitination	YAPPSGDPSIESTDG CCCCCCCCCCCCCCC	40.51	21890473
1292	Ubiquitination	PSGDPSIESTDGAED CCCCCCCCCCCCCCC	52.50	22817900
1294	Ubiquitination	GDPSIESTDGAEDAS CCCCCCCCCCCCCCC	26.18	22817900
1297	Ubiquitination	SIESTDGAEDASLAP CCCCCCCCCCCCCCC	17.82	21890473
1313	Ubiquitination	ESQPITFTPEEMEKY CCCCCCCCHHHHHHH	22.57	21890473
1316	Ubiquitination	PITFTPEEMEKYSKL CCCCCHHHHHHHHHH	54.57	22817900
1319	Ubiquitination	FTPEEMEKYSKLQQA CCHHHHHHHHHHHHH	54.21	22817900
1322	Acetylation	EEMEKYSKLQQAAQQ HHHHHHHHHHHHHHH	47.42	25953088
1322	Ubiquitination	EEMEKYSKLQQAAQQ HHHHHHHHHHHHHHH	47.42	22817900
1322 (in isoform 1)	Ubiquitination	-	47.42	21890473
1338	Ubiquitination	IQQQLLAKQVKAFPA HHHHHHHHHHHHCCH	56.44	22817900
1338 (in isoform 1)	Ubiquitination	-	56.44	21890473
1341	Ubiquitination	QLLAKQVKAFPASAA HHHHHHHHHCCHHHH	41.64	22817900
1348	Ubiquitination	KAFPASAALAPATPA HHCCHHHHCCCCCCC	11.19	22817900
1351	Ubiquitination	PASAALAPATPALQP CHHHHCCCCCCCCCC	37.20	21890473
1367	Ubiquitination	HIQQPATASATSITT CCCCCCCCCCCCCHH	10.16	21890473
1370	Ubiquitination	QPATASATSITTVQH CCCCCCCCCCHHHHH	20.40	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GPTC8_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GPTC8_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GPTC8_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NUMBL_HUMAN	NUMBL	physical	21988832
ABCA2_HUMAN	ABCA2	physical	26496610
ADX_HUMAN	FDX1	physical	26496610
PON2_HUMAN	PON2	physical	26496610
TIM13_HUMAN	TIMM13	physical	26496610
TIM8B_HUMAN	TIMM8B	physical	26496610
TM165_HUMAN	TMEM165	physical	26496610

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GPTC8_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-1142, AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1107, AND MASSSPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-653; SER-1076; SER-1081;SER-1107 AND SER-1109, AND MASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-738; SER-740; SER-758;SER-1033; SER-1035; SER-1076; SER-1081; SER-1107 AND THR-1115, ANDMASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1035, AND MASSSPECTROMETRY.	18220336 [Abstract]
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis."; Wang B., Malik R., Nigg E.A., Korner R.; Anal. Chem. 80:9526-9533(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-758, AND MASSSPECTROMETRY.	19007248 [Abstract]
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-499, AND MASSSPECTROMETRY.	17525332 [Abstract]
"Phosphoproteome analysis of the human mitotic spindle."; Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.; Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1035, AND MASSSPECTROMETRY.	16565220 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1009; SER-1014;TYR-1031; SER-1033 AND SER-1107, AND MASS SPECTROMETRY.	17081983 [Abstract]
"Global phosphoproteome of HT-29 human colon adenocarcinoma cells."; Kim J.-E., Tannenbaum S.R., White F.M.; J. Proteome Res. 4:1339-1346(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-911 AND SER-914, ANDMASS SPECTROMETRY.	16083285 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-650 AND THR-655, ANDMASS SPECTROMETRY.	15302935 [Abstract]