CCD60_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCD60_HUMAN
• UniProt AC: Q8IWA6
• Protein Name: Coiled-coil domain-containing protein 60
• Gene Name: CCDC60
• Organism: Homo sapiens (Human).
• Sequence Length: 550
• Protein Sequence: MTKVPATKKLQSSPNSGAVRPFYASENLRQVPDKPMKSIKYMDKEIINLKKDLIRSRFLIQSVKIGRGYFAILREETAKKKKQQQLQKLKEEERNKFQPAEKISEIHYGDTLLSTYDDEKLKTLGARVTRRPFTPIHSCIISPSLTEAHVEPLFRQLCALHWLLEALTIDHTHHTMKPVITCWNPKDPGGSKSTIKKINKDKSMGQKWEHFITAPKTKKFKIPTMRVTNRKPSRRGSTLSLSRASGGSSPQSSMISVNPGSDEPPSVNTQVTSSKDIEDNESSSTKPDEEPLYMNLQKLLEMVREDARRTVTIENGMQRKAPSILSVLKQNKSNSAYKEMQTTLKSSERSSSTSAESHIQPVQKKSKNRTNCDINIHYKSGVCNTMRAKFYSVAQEAGFCLQDKMEILMKRQEERGIQKFRAFVLVSNFQKDIAKMRHHISVVKGDAEEIADHWYFDLLSKLPEDLKNFRPAKKILVKLQKFGENLDLRIRPHVLLKVLQDLRIWELCSPDIAVAIEFVREHIIHMPQEDYISWLQSRINIPIGPYSALR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	SGAVRPFYASENLRQ CCCCCCEECCCCHHC	16.35	-
38	Phosphorylation	VPDKPMKSIKYMDKE CCCCCCCCCCCCCHH	20.33	-
41	Phosphorylation	KPMKSIKYMDKEIIN CCCCCCCCCCHHHHH	14.63	23403867
203	Phosphorylation	KKINKDKSMGQKWEH HHHHCCCCCCCCEEE	37.97	29978859
213	Phosphorylation	QKWEHFITAPKTKKF CCEEEEECCCCCCCC	35.64	29083192
237	Phosphorylation	RKPSRRGSTLSLSRA CCCCCCCCEEEEEEC	25.10	-
240	Phosphorylation	SRRGSTLSLSRASGG CCCCCEEEEEECCCC	25.12	24719451
242	Phosphorylation	RGSTLSLSRASGGSS CCCEEEEEECCCCCC	23.56	22817900
284	Phosphorylation	IEDNESSSTKPDEEP CCCCCCCCCCCCCCH	50.13	22210691
285	Phosphorylation	EDNESSSTKPDEEPL CCCCCCCCCCCCCHH	48.85	22210691
312	Phosphorylation	EDARRTVTIENGMQR HHHHCCEEECCCHHC	23.20	-
323	Phosphorylation	GMQRKAPSILSVLKQ CHHCCCCHHHHHHHH	40.81	25693802
326	Phosphorylation	RKAPSILSVLKQNKS CCCCHHHHHHHHCCC	24.59	25693802
351	Phosphorylation	LKSSERSSSTSAESH HHHCCCCCCCCCHHH	43.80	30631047
352	Phosphorylation	KSSERSSSTSAESHI HHCCCCCCCCCHHHC	27.85	30631047
353	Phosphorylation	SSERSSSTSAESHIQ HCCCCCCCCCHHHCH	33.63	30631047
354	Phosphorylation	SERSSSTSAESHIQP CCCCCCCCCHHHCHH	31.80	30631047
441	Phosphorylation	AKMRHHISVVKGDAE HHHHHHEEEEECCHH	19.25	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCD60_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCD60_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCD60_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
F204A_HUMAN	FAM204A	physical	28514442
FA32A_HUMAN	FAM32A	physical	28514442
REN3B_HUMAN	UPF3B	physical	28514442
ZN593_HUMAN	ZNF593	physical	28514442
DCP1B_HUMAN	DCP1B	physical	28514442
RBM42_HUMAN	RBM42	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.