FA32A_HUMAN - dbPTM
FA32A_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FA32A_HUMAN
UniProt AC Q9Y421
Protein Name Protein FAM32A
Gene Name FAM32A
Organism Homo sapiens (Human).
Sequence Length 112
Subcellular Localization Isoform 1: Nucleus.
Isoform 2: Nucleus.
Protein Description Isoform 1, but not isoform 2 or isoform 3, may induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli..
Protein Sequence MEAYEQVQKGPLKLKGVAELGVTKRKKKKKDKDKAKLLEAMGTSKKNEEEKRRGLDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
1Acetylation-------MEAYEQVQ
-------CHHHHHHH
6.32-
4Phosphorylation----MEAYEQVQKGP
----CHHHHHHHCCC
8.1225159151
24AcetylationVAELGVTKRKKKKKD
HHHHCCCCCCCCCCC
60.8725953088
43PhosphorylationKLLEAMGTSKKNEEE
HHHHHHCCCCCCHHH
25.04-
44PhosphorylationLLEAMGTSKKNEEEK
HHHHHCCCCCCHHHH
35.58-
59PhosphorylationRRGLDKRTPAQAAFE
HHCCCCCCHHHHHHH
28.8128555341
98PhosphorylationDFNRHLDTLTEHYDI
HHHHHHHHHHHHCCC
41.7729978859
100PhosphorylationNRHLDTLTEHYDIPK
HHHHHHHHHHCCCCC
23.8627642862
103PhosphorylationLDTLTEHYDIPKVSW
HHHHHHHCCCCCCCC
14.8825884760
107UbiquitinationTEHYDIPKVSWTK--
HHHCCCCCCCCCC--
49.59-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FA32A_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FA32A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FA32A_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
A4_HUMANAPPphysical
21832049
CWC22_HUMANCWC22physical
22365833

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FA32A_HUMAN

loading...

Related Literatures of Post-Translational Modification
Acetylation
ReferencePubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, AND MASS SPECTROMETRY.

TOP