dbPTM

HCD2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HCD2_HUMAN
UniProt AC	Q99714
Protein Name	3-hydroxyacyl-CoA dehydrogenase type-2
Gene Name	HSD17B10
Organism	Homo sapiens (Human).
Sequence Length	261
Subcellular Localization	Mitochondrion .
Protein Description	Mitochondrial dehydrogenase that catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. [PubMed: 9553139]
Protein Sequence	MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRLDGAIRMQP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAAACRSVK ------CHHHHHHCC	12.08	25944712
9	Ubiquitination	AAACRSVKGLVAVIT HHHHHHCCCEEEEEE	48.01	-
9	2-Hydroxyisobutyrylation	AAACRSVKGLVAVIT HHHHHHCCCEEEEEE	48.01	-
16	Phosphorylation	KGLVAVITGGASGLG CCEEEEEECCCCHHH	23.98	23828894
20	Phosphorylation	AVITGGASGLGLATA EEEECCCCHHHHHHH	37.51	27251275
36	Phosphorylation	RLVGQGASAVLLDLP HHHCCCCCEEEEECC	26.24	21712546
45	Phosphorylation	VLLDLPNSGGEAQAK EEEECCCCCCHHHHH	46.35	20886841
52	Ubiquitination	SGGEAQAKKLGNNCV CCCHHHHHHHCCCCE	36.13	-
52 (in isoform 2)	Ubiquitination	-	36.13	21890473
52	2-Hydroxyisobutyrylation	SGGEAQAKKLGNNCV CCCHHHHHHHCCCCE	36.13	-
52	Acetylation	SGGEAQAKKLGNNCV CCCHHHHHHHCCCCE	36.13	25953088
52 (in isoform 1)	Ubiquitination	-	36.13	21890473
52	Malonylation	SGGEAQAKKLGNNCV CCCHHHHHHHCCCCE	36.13	26320211
52	Ubiquitination	SGGEAQAKKLGNNCV CCCHHHHHHHCCCCE	36.13	21890473
53	Acetylation	GGEAQAKKLGNNCVF CCHHHHHHHCCCCEE	65.72	25953088
53	Malonylation	GGEAQAKKLGNNCVF CCHHHHHHHCCCCEE	65.72	26320211
53	Succinylation	GGEAQAKKLGNNCVF CCHHHHHHHCCCCEE	65.72	-
53	Ubiquitination	GGEAQAKKLGNNCVF CCHHHHHHHCCCCEE	65.72	-
53	Succinylation	GGEAQAKKLGNNCVF CCHHHHHHHCCCCEE	65.72	-
58	Glutathionylation	AKKLGNNCVFAPADV HHHHCCCCEEECCCC	2.86	22555962
66	Phosphorylation	VFAPADVTSEKDVQT EEECCCCCCHHHHHH	31.54	25627689
67	Phosphorylation	FAPADVTSEKDVQTA EECCCCCCHHHHHHH	42.36	21815630
69	2-Hydroxyisobutyrylation	PADVTSEKDVQTALA CCCCCCHHHHHHHHH	64.07	-
69	Acetylation	PADVTSEKDVQTALA CCCCCCHHHHHHHHH	64.07	25953088
69	Ubiquitination	PADVTSEKDVQTALA CCCCCCHHHHHHHHH	64.07	-
79	Ubiquitination	QTALALAKGKFGRVD HHHHHHHCCCCCCCE	64.58	21890473
79	2-Hydroxyisobutyrylation	QTALALAKGKFGRVD HHHHHHHCCCCCCCE	64.58	-
79 (in isoform 1)	Ubiquitination	-	64.58	21890473
79 (in isoform 2)	Ubiquitination	-	64.58	21890473
79	Acetylation	QTALALAKGKFGRVD HHHHHHHCCCCCCCE	64.58	25038526
79	Ubiquitination	QTALALAKGKFGRVD HHHHHHHCCCCCCCE	64.58	21906983
91	Glutathionylation	RVDVAVNCAGIAVAS CCEEEEECCCEEEEE	2.70	22555962
99 (in isoform 2)	Ubiquitination	-	45.34	21890473
99 (in isoform 1)	Ubiquitination	-	45.34	21890473
99	Acetylation	AGIAVASKTYNLKKG CCEEEEECEEECCCC	45.34	25953088
99	Ubiquitination	AGIAVASKTYNLKKG CCEEEEECEEECCCC	45.34	21890473
99	Ubiquitination	AGIAVASKTYNLKKG CCEEEEECEEECCCC	45.34	21890473
99	Malonylation	AGIAVASKTYNLKKG CCEEEEECEEECCCC	45.34	26320211
105	Ubiquitination	SKTYNLKKGQTHTLE ECEEECCCCCEEEHH	60.46	-
105	Succinylation	SKTYNLKKGQTHTLE ECEEECCCCCEEEHH	60.46	27452117
105	Acetylation	SKTYNLKKGQTHTLE ECEEECCCCCEEEHH	60.46	26051181
105	Malonylation	SKTYNLKKGQTHTLE ECEEECCCCCEEEHH	60.46	26320211
125	Phosphorylation	LDVNLMGTFNVIRLV HCHHCCHHHHHHHHH	9.70	20068231
136	Sulfoxidation	IRLVAGEMGQNEPDQ HHHHHCCCCCCCCCC	7.00	21406390
153	Phosphorylation	QRGVIINTASVAAFE CCCEEEEHHHHHCEE	15.20	18452278
153 (in isoform 2)	Phosphorylation	-	15.20	-
179	Phosphorylation	KGGIVGMTLPIARDL CCCEEEEEECCHHHC	24.37	21406692
194	Sulfoxidation	APIGIRVMTIAPGLF CCCCEEEEEECCCCC	1.29	28183972
195	Phosphorylation	PIGIRVMTIAPGLFG CCCEEEEEECCCCCC	15.89	27542207
203	Phosphorylation	IAPGLFGTPLLTSLP ECCCCCCCHHHHCCC	11.93	27251275
207	Phosphorylation	LFGTPLLTSLPEKVC CCCCHHHHCCCHHHH	35.58	27251275
208	Phosphorylation	FGTPLLTSLPEKVCN CCCHHHHCCCHHHHH	41.73	27542207
212	Acetylation	LLTSLPEKVCNFLAS HHHCCCHHHHHHHHH	50.58	-
212	Succinylation	LLTSLPEKVCNFLAS HHHCCCHHHHHHHHH	50.58	-
212	Succinylation	LLTSLPEKVCNFLAS HHHCCCHHHHHHHHH	50.58	-
214	S-nitrosylation	TSLPEKVCNFLASQV HCCCHHHHHHHHHCC	4.40	19483679
214	S-nitrosocysteine	TSLPEKVCNFLASQV HCCCHHHHHHHHHCC	4.40	-
219	Phosphorylation	KVCNFLASQVPFPSR HHHHHHHHCCCCCHH	33.58	21712546
258	Methylation	IRLDGAIRMQP---- EEECCCEECCC----	19.70	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
-	K	Ubiquitination	E3 ubiquitin ligase	PRKN	O60260	PMID:25591737

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HCD2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HCD2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UB2D1_HUMAN	UBE2D1	physical	21900206
CHD3_HUMAN	CHD3	physical	21900206
FAF1_HUMAN	FAF1	physical	21900206
TGDS_HUMAN	TGDS	physical	22939629
LAMP1_HUMAN	LAMP1	physical	22863883
THIM_HUMAN	ACAA2	physical	26344197
ARP3_HUMAN	ACTR3	physical	26344197
ALDR_HUMAN	AKR1B1	physical	26344197
AK1BF_HUMAN	AKR1B15	physical	26344197
ALDOA_HUMAN	ALDOA	physical	26344197
ALDOC_HUMAN	ALDOC	physical	26344197
ARFG2_HUMAN	ARFGAP2	physical	26344197
ARFG3_HUMAN	ARFGAP3	physical	26344197
GDIR1_HUMAN	ARHGDIA	physical	26344197
GDIR3_HUMAN	ARHGDIG	physical	26344197
ARPC3_HUMAN	ARPC3	physical	26344197
AT1B1_HUMAN	ATP1B1	physical	26344197
BZW1_HUMAN	BZW1	physical	26344197
BZW2_HUMAN	BZW2	physical	26344197
CYBP_HUMAN	CACYBP	physical	26344197
CALU_HUMAN	CALU	physical	26344197
CLIC1_HUMAN	CLIC1	physical	26344197
DLDH_HUMAN	DLD	physical	26344197
EF2_HUMAN	EEF2	physical	26344197
ENOA_HUMAN	ENO1	physical	26344197
ENOG_HUMAN	ENO2	physical	26344197
ENOB_HUMAN	ENO3	physical	26344197
FABP5_HUMAN	FABP5	physical	26344197
FKBP2_HUMAN	FKBP2	physical	26344197
GPX4_HUMAN	GPX4	physical	26344197
ROA2_HUMAN	HNRNPA2B1	physical	26344197
ROA3_HUMAN	HNRNPA3	physical	26344197
ROAA_HUMAN	HNRNPAB	physical	26344197
INO1_HUMAN	ISYNA1	physical	26344197
MYL6_HUMAN	MYL6	physical	26344197
PHB_HUMAN	PHB	physical	26344197
PPIB_HUMAN	PPIB	physical	26344197
DHPR_HUMAN	QDPR	physical	26344197
RTN4_HUMAN	RTN4	physical	26344197
RUVB1_HUMAN	RUVBL1	physical	26344197
SC31A_HUMAN	SEC31A	physical	26344197
S12A4_HUMAN	SLC12A4	physical	26344197
STIP1_HUMAN	STIP1	physical	26344197
TAGL_HUMAN	TAGLN	physical	26344197
TAGL2_HUMAN	TAGLN2	physical	26344197
TAGL3_HUMAN	TAGLN3	physical	26344197
TADBP_HUMAN	TARDBP	physical	26344197
TKT_HUMAN	TKT	physical	26344197
TOM40_HUMAN	TOMM40	physical	26344197
TRIP6_HUMAN	TRIP6	physical	26344197
UBA1_HUMAN	UBA1	physical	26344197
UCHL3_HUMAN	UCHL3	physical	26344197
VAPA_HUMAN	VAPA	physical	26344197
PRKN_HUMAN	PARK2	physical	25591737
ODO1_HUMAN	OGDH	physical	22496890
AL3B1_HUMAN	ALDH3B1	physical	22496890
ATPA_HUMAN	ATP5A1	physical	22496890
CPSM_HUMAN	CPS1	physical	22496890
CISY_HUMAN	CS	physical	22496890
ETFD_HUMAN	ETFDH	physical	22496890
DHE3_HUMAN	GLUD1	physical	22496890
HMGCL_HUMAN	HMGCL	physical	22496890
HMCS2_HUMAN	HMGCS2	physical	22496890
ODPA_HUMAN	PDHA1	physical	22496890
ODPB_HUMAN	PDHB	physical	22496890
ODPX_HUMAN	PDHX	physical	22496890
ECHA_HUMAN	HADHA	physical	22496890
ECHB_HUMAN	HADHB	physical	22496890
ALDOA_HUMAN	ALDOA	physical	22496890
GLNA_HUMAN	GLUL	physical	22496890
MDHC_HUMAN	MDH1	physical	22496890
PYGL_HUMAN	PYGL	physical	22496890
CIKS_HUMAN	TRAF3IP2	physical	22496890
TRAF5_HUMAN	TRAF5	physical	22496890
TRAF6_HUMAN	TRAF6	physical	22496890
CYTC_MOUSE	Cst3	physical	22496890
ODPA_MOUSE	Pdha1	physical	22496890
ODPAT_MOUSE	Pdha2	physical	22496890
PSB5_MOUSE	Psmb5	physical	22496890
A2MG_MOUSE	A2m	physical	22496890
ALDOC_MOUSE	Aldoc	physical	22496890
ENOA_MOUSE	Eno1	physical	22496890
AL3A1_MOUSE	Aldh3a1	physical	22496890
FUMH_MOUSE	Fh1	physical	22496890
DLDH_MOUSE	Dld	physical	22496890
ODO2_MOUSE	Dlst	physical	22496890
ODPX_MOUSE	Pdhx	physical	22496890
IDH3A_MOUSE	Idh3a	physical	22496890
IDHC_MOUSE	Idh1	physical	22496890
KCRB_MOUSE	Ckb	physical	22496890
KCRM_MOUSE	Ckm	physical	22496890
COX5A_MOUSE	Cox5a	physical	22496890
NDUV1_MOUSE	Ndufv1	physical	22496890
NDUV2_MOUSE	Ndufv2	physical	22496890
NDUS2_MOUSE	Ndufs2	physical	22496890
VATL_MOUSE	Atp6v0c	physical	22496890
VA0D1_MOUSE	Atp6v0d1	physical	22496890
VA0E1_MOUSE	Atp6v0e	physical	22496890
VATF_MOUSE	Atp6v1f	physical	22496890
LDHC_MOUSE	Ldhc	physical	22496890
LDHB_MOUSE	Ldhb	physical	22496890
GLNA_MOUSE	Glul	physical	22496890
GSTM1_MOUSE	Gstm1	physical	22496890
GSTA1_MOUSE	Gsta1	physical	22496890
IPYR2_MOUSE	Ppa2	physical	22496890
GATM_MOUSE	Gatm	physical	22496890
OAT_MOUSE	Oat	physical	22496890
ACSM2_MOUSE	Acsm2	physical	22496890
ECHA_MOUSE	Hadha	physical	22496890
ECHB_MOUSE	Hadhb	physical	22496890
ACADV_MOUSE	Acadvl	physical	22496890
CPT2_MOUSE	Cpt2	physical	22496890
HCDH_MOUSE	Hadh	physical	22496890
ACADL_MOUSE	Acadl	physical	22496890
ACOX1_MOUSE	Acox1	physical	22496890
ACADM_MOUSE	Acadm	physical	22496890
ACD10_MOUSE	Acad10	physical	22496890
ACS2L_MOUSE	Acss1	physical	22496890
ECH1_MOUSE	Ech1	physical	22496890
ARGI2_MOUSE	Arg2	physical	22496890
CISY_MOUSE	Cs	physical	22496890
SUCHY_MOUSE	Sugct	physical	22496890
ODB2_MOUSE	Dbt	physical	22496890
DHTK1_MOUSE	Dhtkd1	physical	22496890
3HIDH_MOUSE	Hibadh	physical	22496890
HGD_MOUSE	Hgd	physical	22496890
MDHC_MOUSE	Mdh1	physical	22496890
MCCB_MOUSE	Mccc2	physical	22496890
MCCA_MOUSE	Mccc1	physical	22496890
SUOX_MOUSE	Suox	physical	22496890
PCCA_MOUSE	Pcca	physical	22496890
FAAA_MOUSE	Fah	physical	22496890
ENOB_MOUSE	Eno3	physical	22496890
G3P_MOUSE	Gapdh	physical	22496890
PGK1_MOUSE	Pgk1	physical	22496890
PGAM1_MOUSE	Pgam1	physical	22496890
PGAM2_MOUSE	Pgam2	physical	22496890
SDHA_MOUSE	Sdha	physical	22496890
SDHB_MOUSE	Sdhb	physical	22496890
SUCA_MOUSE	Suclg1	physical	22496890
SUCB2_MOUSE	Suclg2	physical	22496890
ODP2_MOUSE	Dlat	physical	22496890
ETFA_MOUSE	Etfa	physical	22496890
ETFB_MOUSE	Etfb	physical	22496890
ACY1_MOUSE	Acy1	physical	22496890
ACMSD_MOUSE	Acmsd	physical	22496890
EST3A_MOUSE	Ces3a	physical	22496890
LRP2_MOUSE	Lrp2	physical	22496890
LPP60_MOUSE	Aspg	physical	22496890
ARLY_MOUSE	Asl	physical	22496890
ASSY_MOUSE	Ass1	physical	22496890
CH60_MOUSE	Hspd1	physical	22496890
CATA_MOUSE	Cat	physical	22496890
CUBN_MOUSE	Cubn	physical	22496890
DPYL2_MOUSE	Dpysl2	physical	22496890
HEM2_MOUSE	Alad	physical	22496890
GPX1_MOUSE	Gpx1	physical	22496890
PRDX1_MOUSE	Prdx1	physical	22496890
PRDX2_MOUSE	Prdx2	physical	22496890
PRDX5_MOUSE	Prdx5	physical	22496890
PRDX6_MOUSE	Prdx6	physical	22496890
TPIS_MOUSE	Tpi1	physical	22496890
LDHA_MOUSE	Ldha	physical	22496890
G6PI_MOUSE	Gpi1	physical	22496890
ENOG_MOUSE	Eno2	physical	22496890
ODPB_MOUSE	Pdhb	physical	22496890
KPYM_MOUSE	Pkm	physical	22496890
ODO1_MOUSE	Ogdh	physical	22496890
GSTA4_MOUSE	Gsta4	physical	22496890
GSTM2_MOUSE	Gstm2	physical	22496890
GSTM5_MOUSE	Gstm5	physical	22496890
GSTP1_MOUSE	Gstp1	physical	22496890
GSTT1_MOUSE	Gstt1	physical	22496890
FABPL_MOUSE	Fabp1	physical	22496890
HSPB2_MOUSE	Hspb2	physical	22496890
HSPB6_MOUSE	Hspb6	physical	22496890
IVD_MOUSE	Ivd	physical	22496890
MYH4_MOUSE	Myh4	physical	22496890
PUR6_MOUSE	Paics	physical	22496890
ADH4_MOUSE	Adh4	physical	22496890
NDUA7_MOUSE	Ndufa7	physical	22496890
CAH3_MOUSE	Car3	physical	22496890
PYGB_MOUSE	Pygb	physical	22496890
THIM_MOUSE	Acaa2	physical	22496890
GSTO1_MOUSE	Gsto1	physical	22496890
ACADS_MOUSE	Acads	physical	22496890
CPSM_MOUSE	Cps1	physical	22496890
ACNT1_MOUSE	Acnat1	physical	22496890
HMGCL_MOUSE	Hmgcl	physical	22496890
HMCS1_MOUSE	Hmgcs1	physical	22496890
MRRP1_HUMAN	TRMT10C	physical	28514442
PRDX2_HUMAN	PRDX2	physical	29128334
RL30_HUMAN	RPL30	physical	29128334
EF2_HUMAN	EEF2	physical	29128334
PPIA_HUMAN	PPIA	physical	29128334
PIMT_HUMAN	PCMT1	physical	29128334
PRDX6_HUMAN	PRDX6	physical	29128334
RB11A_HUMAN	RAB11A	physical	29128334
RHOA_HUMAN	RHOA	physical	29128334
TCPQ_HUMAN	CCT8	physical	29128334
EIF3I_HUMAN	EIF3I	physical	29128334
ML12A_HUMAN	MYL12A	physical	29128334
TCPB_HUMAN	CCT2	physical	29128334
PABP1_HUMAN	PABPC1	physical	29128334
BAX_HUMAN	BAX	physical	29128334
NOP10_HUMAN	NOP10	physical	29128334
RUVB2_HUMAN	RUVBL2	physical	29128334
TIF1B_HUMAN	TRIM28	physical	29128334
NACAM_HUMAN	NACA	physical	29128334
NACA_HUMAN	NACA	physical	29128334
PSMD7_HUMAN	PSMD7	physical	29128334
MDHM_HUMAN	MDH2	physical	29128334
PTBP1_HUMAN	PTBP1	physical	29128334
GDIR1_HUMAN	ARHGDIA	physical	29128334
ENPL_HUMAN	HSP90B1	physical	29128334
RAC1_HUMAN	RAC1	physical	29128334
PSD11_HUMAN	PSMD11	physical	29128334
PSME2_HUMAN	PSME2	physical	29128334
NH2L1_HUMAN	NHP2L1	physical	29128334
ILF2_HUMAN	ILF2	physical	29128334
MCA3_HUMAN	EEF1E1	physical	29128334
PDIA6_HUMAN	PDIA6	physical	29128334
XRCC6_HUMAN	XRCC6	physical	29128334
RL10A_HUMAN	RPL10A	physical	29128334
SUMO2_HUMAN	SUMO2	physical	29128334
PRDX3_HUMAN	PRDX3	physical	29128334
EF1G_HUMAN	EEF1G	physical	29128334
PRS10_HUMAN	PSMC6	physical	29128334
IF4A3_HUMAN	EIF4A3	physical	29128334
HBB_HUMAN	HBB	physical	29128334
CDK1_HUMAN	CDK1	physical	29128334
BASI_HUMAN	BSG	physical	29128334
EF1D_HUMAN	EEF1D	physical	29128334
UBA1_HUMAN	UBA1	physical	29128334
MOB1B_HUMAN	MOB1B	physical	29128334
PIPNB_HUMAN	PITPNB	physical	29128334
TCPH_HUMAN	CCT7	physical	29128334
GBB1_HUMAN	GNB1	physical	29128334
NP1L1_HUMAN	NAP1L1	physical	29128334
HPRT_HUMAN	HPRT1	physical	29128334
PRS8_HUMAN	PSMC5	physical	29128334
SYDC_HUMAN	DARS	physical	29128334
THIL_HUMAN	ACAT1	physical	29128334
ANXA2_HUMAN	ANXA2	physical	29128334
RA1L2_HUMAN	HNRNPA1L2	physical	29128334
SYK_HUMAN	KARS	physical	29128334
TAGL2_HUMAN	TAGLN2	physical	29128334
H2A1D_HUMAN	HIST1H2AD	physical	29128334
ELAV1_HUMAN	ELAVL1	physical	29128334
SPIN1_HUMAN	SPIN1	physical	29128334
RALY_HUMAN	RALY	physical	29128334
HNRH3_HUMAN	HNRNPH3	physical	29128334
RPAB1_HUMAN	POLR2E	physical	29128334
HNRDL_HUMAN	HNRNPDL	physical	29128334
TMEDA_HUMAN	TMED10	physical	29128334
TPIS_HUMAN	TPI1	physical	29128334
PP1A_HUMAN	PPP1CA	physical	29128334
PRP19_HUMAN	PRPF19	physical	29128334
PRS4_HUMAN	PSMC1	physical	29128334
MCM3_HUMAN	MCM3	physical	29128334
RPAB3_HUMAN	POLR2H	physical	29128334
EF1B_HUMAN	EEF1B2	physical	29128334
RUVB1_HUMAN	RUVBL1	physical	29128334
RNPS1_HUMAN	RNPS1	physical	29128334
PSMD3_HUMAN	PSMD3	physical	29128334
HDAC1_HUMAN	HDAC1	physical	29128334
CPVL_HUMAN	CPVL	physical	29128334
CHTOP_HUMAN	CHTOP	physical	29128334
XRCC5_HUMAN	XRCC5	physical	29128334
SF3B6_HUMAN	SF3B6	physical	29128334
PAIRB_HUMAN	SERBP1	physical	29128334
MYL1_HUMAN	MYL1	physical	29128334
NAA50_HUMAN	NAA50	physical	29128334
RMXL2_HUMAN	RBMXL2	physical	29128334
SYAC_HUMAN	AARS	physical	29128334
PSD12_HUMAN	PSMD12	physical	29128334
EIF3D_HUMAN	EIF3D	physical	29128334
VINC_HUMAN	VCL	physical	29128334
M4K1_HUMAN	MAP4K1	physical	29128334
BACH_HUMAN	ACOT7	physical	29128334
IMB1_HUMAN	KPNB1	physical	29128334
METK2_HUMAN	MAT2A	physical	29128334
PLP2_HUMAN	PLP2	physical	29128334
COPE_HUMAN	COPE	physical	29128334
MCM2_HUMAN	MCM2	physical	29128334
PSDE_HUMAN	PSMD14	physical	29128334
RTCB_HUMAN	RTCB	physical	29128334
CH10_HUMAN	HSPE1	physical	29128334
CSN8_HUMAN	COPS8	physical	29128334
SERPH_HUMAN	SERPINH1	physical	29128334
MCM5_HUMAN	MCM5	physical	29128334
CSK2B_HUMAN	CSNK2B	physical	29128334
MCM4_HUMAN	MCM4	physical	29128334
BUB3_HUMAN	BUB3	physical	29128334
2AAA_HUMAN	PPP2R1A	physical	29128334
PSME3_HUMAN	PSME3	physical	29128334
RBBP7_HUMAN	RBBP7	physical	29128334
CD2B2_HUMAN	CD2BP2	physical	29128334
SAE2_HUMAN	UBA2	physical	29128334
FEN1_HUMAN	FEN1	physical	29128334
NP1L4_HUMAN	NAP1L4	physical	29128334
BID_HUMAN	BID	physical	29128334
PGRC1_HUMAN	PGRMC1	physical	29128334
NAMPT_HUMAN	NAMPT	physical	29128334
THOC4_HUMAN	ALYREF	physical	29128334
PSMD6_HUMAN	PSMD6	physical	29128334
OTUB1_HUMAN	OTUB1	physical	29128334
TRAP1_HUMAN	TRAP1	physical	29128334
PERI_HUMAN	PRPH	physical	29128334
ROAA_HUMAN	HNRNPAB	physical	29128334
CPSF6_HUMAN	CPSF6	physical	29128334
PRS6B_HUMAN	PSMC4	physical	29128334
ENOB_HUMAN	ENO3	physical	29128334
PI42C_HUMAN	PIP4K2C	physical	29128334
DKC1_HUMAN	DKC1	physical	29128334
NOP58_HUMAN	NOP58	physical	29128334
HNRL2_HUMAN	HNRNPUL2	physical	29128334
PYRG1_HUMAN	CTPS1	physical	29128334
ARP2_HUMAN	ACTR2	physical	29128334
NCBP1_HUMAN	NCBP1	physical	29128334
FAS_HUMAN	FASN	physical	29128334
PSMD1_HUMAN	PSMD1	physical	29128334
PDC6I_HUMAN	PDCD6IP	physical	29128334
CTNA1_HUMAN	CTNNA1	physical	29128334
CCAR2_HUMAN	CCAR2	physical	29128334
DD19A_HUMAN	DDX19A	physical	29128334
DYHC1_HUMAN	DYNC1H1	physical	29128334
MYO6_HUMAN	MYO6	physical	29128334
H2A1B_HUMAN	HIST1H2AE	physical	29128334
HBA_HUMAN	HBA1	physical	29128334
UB2V1_HUMAN	UBE2V1	physical	29128334

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
300438	2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD deficiency)
300220	Mental retardation, X-linked, syndromic, 10 (MRXS10)
300705	Mental retardation, X-linked 17 (MRX17)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HCD2_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, AND MASS SPECTROMETRY.	19413330 [Abstract]