dbPTM

GSTT1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GSTT1_MOUSE
UniProt AC	Q64471
Protein Name	Glutathione S-transferase theta-1
Gene Name	Gstt1
Organism	Mus musculus (Mouse).
Sequence Length	240
Subcellular Localization	Cytoplasm. Nucleus.
Protein Description	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity..
Protein Sequence	MVLELYLDLLSQPCRAIYIFAKKNNIPFQMHTVELRKGEHLSDAFARVNPMKRVPAMMDGGFTLCESVAILLYLAHKYKVPDHWYPQDLQARARVDEYLAWQHTGLRRSCLRALWHKVMFPVFLGEQIPPETLAATLAELDVNLQVLEDKFLQDKDFLVGPHISLADLVAITELMHPVGGGCPVFEGHPRLAAWYQRVEAAVGKDLFREAHEVILKVKDCPPADLIIKQKLMPRVLAMIQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Succinylation	RAIYIFAKKNNIPFQ EEEEEECCCCCCCEE	45.33	23954790
23	Ubiquitination	AIYIFAKKNNIPFQM EEEEECCCCCCCEEE	52.37	-
23	Malonylation	AIYIFAKKNNIPFQM EEEEECCCCCCCEEE	52.37	26320211
37	Ubiquitination	MHTVELRKGEHLSDA EEEEEEECCCCHHHH	79.75	-
37	Malonylation	MHTVELRKGEHLSDA EEEEEEECCCCHHHH	79.75	26320211
79	Acetylation	LYLAHKYKVPDHWYP HHHHHHHCCCCCCCC	52.69	22733758
204	Acetylation	RVEAAVGKDLFREAH HHHHHHCHHHHHHHH	44.66	23954790
204	Ubiquitination	RVEAAVGKDLFREAH HHHHHHCHHHHHHHH	44.66	-
204	Malonylation	RVEAAVGKDLFREAH HHHHHHCHHHHHHHH	44.66	25418362
216	Acetylation	EAHEVILKVKDCPPA HHHHHHHHCCCCCHH	35.79	23201123

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GSTT1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GSTT1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GSTT1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of GSTT1_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GSTT1_MOUSE

Related Literatures of Post-Translational Modification