VATF_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VATF_MOUSE
• UniProt AC: Q9D1K2
• Protein Name: V-type proton ATPase subunit F
• Gene Name: Atp6v1f
• Organism: Mus musculus (Mouse).
• Sequence Length: 119
• Protein Description: Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells..
• Protein Sequence: MAGRGKLIAVIGDEDTVTGFLLGGIGELNKNRHPNFLVVEKDTTINEIEDTFRQFLNRDDIGIILINQYIAEMVRHALDAHQRSIPAVLEIPSKEHPYDAAKDSILRRAKGMFTAEDLR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Ubiquitination	GGIGELNKNRHPNFL ECHHHHCCCCCCCEE	68.90	-
84	Phosphorylation	ALDAHQRSIPAVLEI HHHHHHCCCCEEEEC	26.76	22817900
93	Phosphorylation	PAVLEIPSKEHPYDA CEEEECCCCCCCCHH	57.23	22817900
94	Ubiquitination	AVLEIPSKEHPYDAA EEEECCCCCCCCHHH	55.47	22790023
102	Ubiquitination	EHPYDAAKDSILRRA CCCCHHHHHHHHHHH	54.45	22790023
104	Phosphorylation	PYDAAKDSILRRAKG CCHHHHHHHHHHHCC	23.86	29899451
110	Ubiquitination	DSILRRAKGMFTAED HHHHHHHCCCCCHHH	49.44	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VATF_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VATF_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VATF_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of VATF_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.