ACADS_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ACADS_MOUSE
• UniProt AC: Q07417
• Protein Name: Short-chain specific acyl-CoA dehydrogenase, mitochondrial
• Gene Name: Acads
• Organism: Mus musculus (Mouse).
• Sequence Length: 412
• Subcellular Localization: Mitochondrion matrix.
• Protein Description: Introduces a double bond at position 2 in saturated acyl-CoA's of short chain length, i.e. less than 6 carbon atoms..
• Protein Sequence: MAAALLARARGPLRRALGVRDWRRLHTVYQSVELPETHQMLRQTCRDFAEKELVPIAAQLDREHLFPTAQVKKMGELGLLAMDVPEELSGAGLDYLAYSIALEEISRACASTGVIMSVNNSLYLGPILKFGSAQQKQQWITPFTNGDKIGCFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDMGRIGIASQALGIAQASLDCAVKYAENRNAFGAPLTKLQNIQFKLADMALALESARLLTWRAAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYEGTSEIQRLVIAGHLLRSYRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
27	Phosphorylation	RDWRRLHTVYQSVEL CCHHHHHHHHHCCCC	26.04	22817900
29	Phosphorylation	WRRLHTVYQSVELPE HHHHHHHHHCCCCHH	9.02	21183079
51	Acetylation	TCRDFAEKELVPIAA HHHHHHHHCHHHHHH	53.57	23576753
51	Succinylation	TCRDFAEKELVPIAA HHHHHHHHCHHHHHH	53.57	-
51	Succinylation	TCRDFAEKELVPIAA HHHHHHHHCHHHHHH	53.57	23806337
72	Acetylation	LFPTAQVKKMGELGL CCCHHHHHCHHHHCC	25.59	23576753
72	Succinylation	LFPTAQVKKMGELGL CCCHHHHHCHHHHCC	25.59	23954790
129	Acetylation	LYLGPILKFGSAQQK EECCCCEECCCHHHC	48.69	23576753
129	Succinylation	LYLGPILKFGSAQQK EECCCCEECCCHHHC	48.69	-
129	Succinylation	LYLGPILKFGSAQQK EECCCCEECCCHHHC	48.69	23806337
136	Acetylation	KFGSAQQKQQWITPF ECCCHHHCCCCEECC	32.17	23864654
136	Succinylation	KFGSAQQKQQWITPF ECCCHHHCCCCEECC	32.17	24315375
148	Acetylation	TPFTNGDKIGCFALS ECCCCCCEEEEEEEC	42.25	23864654
151	S-nitrosylation	TNGDKIGCFALSEPG CCCCEEEEEEECCCC	1.73	21278135
151	S-palmitoylation	TNGDKIGCFALSEPG CCCCEEEEEEECCCC	1.73	28526873
151	S-nitrosocysteine	TNGDKIGCFALSEPG CCCCEEEEEEECCCC	1.73	-
161	Phosphorylation	LSEPGNGSDAGAAST ECCCCCCCCCCCCCC	28.43	26525534
208	Succinylation	TDRSRQNKGISAFLV CCHHHCCCCCCEEEE	49.65	24315375
208	Acetylation	TDRSRQNKGISAFLV CCHHHCCCCCCEEEE	49.65	23576753
219	Phosphorylation	AFLVPMPTPGLTLGK EEEEECCCCCCCCCC	24.60	22871156
223	Phosphorylation	PMPTPGLTLGKKEDK ECCCCCCCCCCCCCC	39.10	22871156
226	Acetylation	TPGLTLGKKEDKLGI CCCCCCCCCCCCCCC	56.98	23576753
246	S-nitrosylation	ANLIFEDCRIPKENL CCHHHCCCCCCHHHC	3.15	21278135
246	S-nitrosocysteine	ANLIFEDCRIPKENL CCHHHCCCCCCHHHC	3.15	-
250	Acetylation	FEDCRIPKENLLGEP HCCCCCCHHHCCCCC	57.79	22826441
262	Acetylation	GEPGMGFKIAMQTLD CCCCCCHHHEEECCC	24.67	23576753
262	Succinylation	GEPGMGFKIAMQTLD CCCCCCHHHEEECCC	24.67	-
262	Succinylation	GEPGMGFKIAMQTLD CCCCCCHHHEEECCC	24.67	23806337
289	Glutathionylation	IAQASLDCAVKYAEN HHHHHHHHHHHHHHH	5.94	24333276
289	S-nitrosocysteine	IAQASLDCAVKYAEN HHHHHHHHHHHHHHH	5.94	-
289	S-nitrosylation	IAQASLDCAVKYAEN HHHHHHHHHHHHHHH	5.94	20925432
292	Acetylation	ASLDCAVKYAENRNA HHHHHHHHHHHHCCC	21.88	23576753
305	Phosphorylation	NAFGAPLTKLQNIQF CCCCCCCHHHHHCHH	28.75	22817900
306	Ubiquitination	AFGAPLTKLQNIQFK CCCCCCHHHHHCHHH	56.62	-
306	Acetylation	AFGAPLTKLQNIQFK CCCCCCHHHHHCHHH	56.62	23576753
306	Succinylation	AFGAPLTKLQNIQFK CCCCCCHHHHHCHHH	56.62	-
306	Glutarylation	AFGAPLTKLQNIQFK CCCCCCHHHHHCHHH	56.62	24703693
306	Succinylation	AFGAPLTKLQNIQFK CCCCCCHHHHHCHHH	56.62	23806337
335	Succinylation	TWRAAMLKDNKKPFT HHHHHHHHCCCCCCC	46.28	23806337
335	Glutarylation	TWRAAMLKDNKKPFT HHHHHHHHCCCCCCC	46.28	24703693
335	Acetylation	TWRAAMLKDNKKPFT HHHHHHHHCCCCCCC	46.28	23806337
338	Glutarylation	AAMLKDNKKPFTKES HHHHHCCCCCCCHHH	72.46	24703693
338	Acetylation	AAMLKDNKKPFTKES HHHHHCCCCCCCHHH	72.46	23864654
339	Acetylation	AMLKDNKKPFTKESA HHHHCCCCCCCHHHH	52.17	23201123
343	Acetylation	DNKKPFTKESAMAKL CCCCCCCHHHHHHHH	50.48	23201123
343	Succinylation	DNKKPFTKESAMAKL CCCCCCCHHHHHHHH	50.48	23954790
388	Phosphorylation	YYRDARITEIYEGTS HHHHCCCEEEEECCH	15.69	22324799
391	Phosphorylation	DARITEIYEGTSEIQ HCCCEEEEECCHHHH	11.32	22324799
394	Phosphorylation	ITEIYEGTSEIQRLV CEEEEECCHHHHHHH	15.96	22324799
395	Phosphorylation	TEIYEGTSEIQRLVI EEEEECCHHHHHHHH	43.49	22324799

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ACADS_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ACADS_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ACADS_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ACADS_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.