GSTM5_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GSTM5_MOUSE
• UniProt AC: P48774
• Protein Name: Glutathione S-transferase Mu 5
• Gene Name: Gstm5
• Organism: Mus musculus (Mouse).
• Sequence Length: 224
• Subcellular Localization: Cytoplasm.
• Protein Description: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles..
• Protein Sequence: MSSKSMVLGYWDIRGLAHAIRMLLEFTDTSYEEKRYICGEAPDYDRSQWLDVKFKLDLDFPNLPYLMDGKNKITQSNAILRYIARKHNMCGDTEEEKIRVDIMENQIMDFRMQLVRLCYNSNHENLKPQYLEQLPAQLKQFSLFLGKFTWFAGEKLTFVDFLTYDVLDQNRIFEPKCLDEFPNLKAFMCRFEALEKIAAFLQSDRFFKMPINNKMAKWGNKCLC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Ubiquitination	----MSSKSMVLGYW ----CCCCCCHHCHH	34.95	22790023
4	Sumoylation	----MSSKSMVLGYW ----CCCCCCHHCHH	34.95	28289178
5	Phosphorylation	---MSSKSMVLGYWD ---CCCCCCHHCHHH	18.97	19186949
34	Ubiquitination	TDTSYEEKRYICGEA CCCCHHHHCCCCCCC	38.26	22790023
38	S-palmitoylation	YEEKRYICGEAPDYD HHHHCCCCCCCCCCC	2.74	28526873
38	S-nitrosylation	YEEKRYICGEAPDYD HHHHCCCCCCCCCCC	2.74	21278135
38	S-nitrosocysteine	YEEKRYICGEAPDYD HHHHCCCCCCCCCCC	2.74	-
70	Ubiquitination	LPYLMDGKNKITQSN CCEEECCCCCHHCHH	51.29	22790023
72	Ubiquitination	YLMDGKNKITQSNAI EEECCCCCHHCHHHH	51.09	22790023
76	Phosphorylation	GKNKITQSNAILRYI CCCCHHCHHHHHHHH	21.41	26643407
86	Acetylation	ILRYIARKHNMCGDT HHHHHHHHCCCCCCC	30.24	22826441
90	S-nitrosocysteine	IARKHNMCGDTEEEK HHHHCCCCCCCCHHH	5.60	-
90	S-nitrosylation	IARKHNMCGDTEEEK HHHHCCCCCCCCHHH	5.60	21278135
93	Phosphorylation	KHNMCGDTEEEKIRV HCCCCCCCCHHHHHH	30.49	29514104
119	Phosphorylation	MQLVRLCYNSNHENL HHHHHHHHCCCCCCC	26.64	29899451
121	Phosphorylation	LVRLCYNSNHENLKP HHHHHHCCCCCCCCH	17.06	29899451
127	Ubiquitination	NSNHENLKPQYLEQL CCCCCCCCHHHHHHH	41.47	22790023
127	Acetylation	NSNHENLKPQYLEQL CCCCCCCCHHHHHHH	41.47	22826441
176	Ubiquitination	QNRIFEPKCLDEFPN CCCCCCCHHHHCCCC	39.99	22790023
196	Acetylation	CRFEALEKIAAFLQS HHHHHHHHHHHHHHC	38.20	22826441
208	Ubiquitination	LQSDRFFKMPINNKM HHCCCCCCCCCCCCC	40.84	22790023
214	Ubiquitination	FKMPINNKMAKWGNK CCCCCCCCCCCCCCC	35.43	27667366

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GSTM5_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GSTM5_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GSTM5_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of GSTM5_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.