SUOX_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SUOX_MOUSE
• UniProt AC: Q8R086
• Protein Name: Sulfite oxidase, mitochondrial
• Gene Name: Suox
• Organism: Mus musculus (Mouse).
• Sequence Length: 546
• Subcellular Localization: Mitochondrion intermembrane space.
• Protein Sequence: MLLQLYRSVVVRLPQAIRVKSTPLRLCIQACSTNDSLEPQHPSLTFSDDNSRTRRWKVMGTLLGLGVVLVYHEHRCRASQESPRMYSKEDVRSHNNPKTGVWVTLGSEVFDVTKFVDLHPGGPSKLMLAAGGPLEPFWALYAVHNQPHVRELLAEYKIGELNPEDSMSPSVEASDPYADDPIRHPALRINSQRPFNAEPPPELLTEGYITPNPIFFTRNHLPVPNLDPHTYRLHVVGAPGGQSLSLSLDDLHKFPKHEVTVTLQCAGNRRSEMSKVKEVKGLEWRTGAISTARWAGARLCDVLAQAGHRLCDSEAHVCFEGLDSDPTGTAYGASIPLARAMDPEAEVLLAYEMNGQPLPRDHGFPVRVVVPGVVGARHVKWLGRVSVESEESYSHWQRRDYKGFSPSVDWDTVNFDLAPSIQELPIQSAITQPQDGAIVESGEVTIKGYAWSGGGRAVIRVDVSVDGGLTWQEAELEGEEQCPRKAWAWRIWQLKAQVPAEQKELNIICKAVDDSYNVQPDTVAPIWNLRGVLSNAWHRVHVQVVP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	PQAIRVKSTPLRLCI CCCEECCCCCCHHHE	32.19	24719451
87	Phosphorylation	QESPRMYSKEDVRSH CCCCCCCCHHHHHHC	21.89	24719451
88	Malonylation	ESPRMYSKEDVRSHN CCCCCCCHHHHHHCC	40.21	26320211
88	Succinylation	ESPRMYSKEDVRSHN CCCCCCCHHHHHHCC	40.21	23806337
88	Acetylation	ESPRMYSKEDVRSHN CCCCCCCHHHHHHCC	40.21	23806337
124	Phosphorylation	DLHPGGPSKLMLAAG ECCCCCCHHEEEECC	41.52	22324799
253	Acetylation	LSLDDLHKFPKHEVT EEHHHHHCCCCCEEE	71.33	23954790
253	Ubiquitination	LSLDDLHKFPKHEVT EEHHHHHCCCCCEEE	71.33	22790023
260	Phosphorylation	KFPKHEVTVTLQCAG CCCCCEEEEEEEECC	12.56	28576409
262	Phosphorylation	PKHEVTVTLQCAGNR CCCEEEEEEEECCCC	11.18	28576409
265	S-nitrosocysteine	EVTVTLQCAGNRRSE EEEEEEEECCCCCHH	6.19	-
265	S-nitrosylation	EVTVTLQCAGNRRSE EEEEEEEECCCCCHH	6.19	22178444
265	S-palmitoylation	EVTVTLQCAGNRRSE EEEEEEEECCCCCHH	6.19	26165157
280	Ubiquitination	MSKVKEVKGLEWRTG HHCCEEECCCCCCCC	59.89	-
280	Acetylation	MSKVKEVKGLEWRTG HHCCEEECCCCCCCC	59.89	23864654
280	Malonylation	MSKVKEVKGLEWRTG HHCCEEECCCCCCCC	59.89	26320211
286	Phosphorylation	VKGLEWRTGAISTAR ECCCCCCCCCHHHHH	31.85	17203969
300	S-nitrosocysteine	RWAGARLCDVLAQAG HHHHHHHHHHHHHHC	2.57	-
300	S-nitrosylation	RWAGARLCDVLAQAG HHHHHHHHHHHHHHC	2.57	22178444
300	S-palmitoylation	RWAGARLCDVLAQAG HHHHHHHHHHHHHHC	2.57	28526873
389	Phosphorylation	LGRVSVESEESYSHW EEEEEECCCCCCCCH	44.50	-
495	Succinylation	AWRIWQLKAQVPAEQ HHHHHHHCCCCCHHH	22.98	23954790
503	Acetylation	AQVPAEQKELNIICK CCCCHHHHHHEEEEE	56.53	23864654
503	Malonylation	AQVPAEQKELNIICK CCCCHHHHHHEEEEE	56.53	26320211

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SUOX_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SUOX_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SUOX_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SUOX_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Protein phosphorylation and expression profiling by Yin-yangmultidimensional liquid chromatography (Yin-yang MDLC) massspectrometry.";
Dai J., Jin W.-H., Sheng Q.-H., Shieh C.-H., Wu J.-R., Zeng R.;
J. Proteome Res. 6:250-262(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-286, AND MASSSPECTROMETRY.
PubMed: 17203969