CYTC_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CYTC_MOUSE
• UniProt AC: P21460
• Protein Name: Cystatin-C
• Gene Name: Cst3
• Organism: Mus musculus (Mouse).
• Sequence Length: 140
• Subcellular Localization: Secreted.
• Protein Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity..
• Protein Sequence: MASPLRSLLFLLAVLAVAWAATPKQGPRMLGAPEEADANEEGVRRALDFAVSEYNKGSNDAYHSRAIQVVRARKQLVAGVNYFLDVEMGRTTCTKSQTNLTDCPFHDQPHLMRKALCSFQIYSVPWKGTHSLTKFSCKNA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
56	Ubiquitination	FAVSEYNKGSNDAYH HHHHHHCCCCCCHHH	63.92	-
103	Glutathionylation	SQTNLTDCPFHDQPH CCCCCCCCCCCCCHH	3.06	24333276
137	Glutathionylation	HSLTKFSCKNA---- CCCEEEEECCC----	4.42	24333276

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CYTC_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CYTC_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CYTC_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CYTC_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.