NDUA7_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NDUA7_MOUSE
• UniProt AC: Q9Z1P6
• Protein Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
• Gene Name: Ndufa7
• Organism: Mus musculus (Mouse).
• Sequence Length: 113
• Subcellular Localization: Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
• Protein Description: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone..
• Protein Sequence: MASATRVIQKLRNWASGQDLQAKLQLRYQEIAKRTQPPPKLPVGPSHKLSNNYYCTRDGRREVVPPSIIMSSQKALVSGKAAESSAMAATEKKAVTPAPPMKRWELSKDQPYL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MASATRVIQ ------CCHHHHHHH	14.10	-
33	Acetylation	LRYQEIAKRTQPPPK HHHHHHHHHCCCCCC	62.73	2416679
35	Phosphorylation	YQEIAKRTQPPPKLP HHHHHHHCCCCCCCC	44.73	25195567
40	Acetylation	KRTQPPPKLPVGPSH HHCCCCCCCCCCCCC	71.80	23576753
40	Succinylation	KRTQPPPKLPVGPSH HHCCCCCCCCCCCCC	71.80	24315375
40	Malonylation	KRTQPPPKLPVGPSH HHCCCCCCCCCCCCC	71.80	26320211
48	Acetylation	LPVGPSHKLSNNYYC CCCCCCCCCCCCEEE	58.93	24062335
53	Phosphorylation	SHKLSNNYYCTRDGR CCCCCCCEEECCCCC	12.27	29514104
55	S-palmitoylation	KLSNNYYCTRDGRRE CCCCCEEECCCCCCC	1.45	28526873
55	S-nitrosylation	KLSNNYYCTRDGRRE CCCCCEEECCCCCCC	1.45	21278135
55	S-nitrosocysteine	KLSNNYYCTRDGRRE CCCCCEEECCCCCCC	1.45	-
85	Phosphorylation	SGKAAESSAMAATEK CCHHHHHHHHHHHHC	17.36	27742792
92	Acetylation	SAMAATEKKAVTPAP HHHHHHHCCCCCCCC	41.50	23201123
96	Phosphorylation	ATEKKAVTPAPPMKR HHHCCCCCCCCCCCC	20.70	-
102	Acetylation	VTPAPPMKRWELSKD CCCCCCCCCCCCCCC	61.20	23201123
102	Succinylation	VTPAPPMKRWELSKD CCCCCCCCCCCCCCC	61.20	26388266
108	Acetylation	MKRWELSKDQPYL-- CCCCCCCCCCCCC--	73.36	23864654
108	Succinylation	MKRWELSKDQPYL-- CCCCCCCCCCCCC--	73.36	26388266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NDUA7_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NDUA7_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NDUA7_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NDUA7_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.