dbPTM

CPSM_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CPSM_HUMAN
UniProt AC	P31327
Protein Name	Carbamoyl-phosphate synthase [ammonia], mitochondrial
Gene Name	CPS1
Organism	Homo sapiens (Human).
Sequence Length	1500
Subcellular Localization	Mitochondrion . Nucleus, nucleolus .
Protein Description	Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell..
Protein Sequence	MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7 (in isoform 2)	Ubiquitination	-	9.98	-
21	Ubiquitination	LKTGFGFTNVTAHQK CCCCCCCCCCCCCCC	29.20	-
32	Phosphorylation	AHQKWKFSRPGIRLL CCCCCCCCCCCEEEE	33.56	24719451
38	Phosphorylation	FSRPGIRLLSVKAQT CCCCCEEEEEEEEEE	3.85	24719451
40	Phosphorylation	RPGIRLLSVKAQTAH CCCEEEEEEEEEEEE	26.60	24719451
45	Phosphorylation	LLSVKAQTAHIVLED EEEEEEEEEEEEECC	25.68	24114839
46	Phosphorylation	LSVKAQTAHIVLEDG EEEEEEEEEEEECCC	4.37	24719451
51	Phosphorylation	QTAHIVLEDGTKMKG EEEEEEECCCCEEEC	43.42	-
55	Acetylation	IVLEDGTKMKGYSFG EEECCCCEEECCCCC	44.11	26051181
55	Glutarylation	IVLEDGTKMKGYSFG EEECCCCEEECCCCC	44.11	24703693
55	Succinylation	IVLEDGTKMKGYSFG EEECCCCEEECCCCC	44.11	-
55	Succinylation	IVLEDGTKMKGYSFG EEECCCCEEECCCCC	44.11	-
57	Acetylation	LEDGTKMKGYSFGHP ECCCCEEECCCCCCC	57.14	26051181
57	Succinylation	LEDGTKMKGYSFGHP ECCCCEEECCCCCCC	57.14	-
57	Succinylation	LEDGTKMKGYSFGHP ECCCCEEECCCCCCC	57.14	-
61	Acetylation	TKMKGYSFGHPSSVA CEEECCCCCCCHHCC	8.63	-
76 (in isoform 2)	Ubiquitination	-	24.35	-
109 (in isoform 2)	Ubiquitination	-	16.95	-
119	Acetylation	LDELGLSKYLESNGI HHHHCHHHHHHHCCC	59.92	23954790
119	Succinylation	LDELGLSKYLESNGI HHHHCHHHHHHHCCC	59.92	-
119	Succinylation	LDELGLSKYLESNGI HHHHCHHHHHHHCCC	59.92	23954790
125	Acetylation	SKYLESNGIKVSGLL HHHHHHCCCEEEEEE	30.30	-
125	Ubiquitination	SKYLESNGIKVSGLL HHHHHHCCCEEEEEE	30.30	-
129	Phosphorylation	ESNGIKVSGLLVLDY HHCCCEEEEEEEEEC	20.79	21712546
135	Phosphorylation	VSGLLVLDYSKDYNH EEEEEEEECCCCCCH	37.87	-
136	Phosphorylation	SGLLVLDYSKDYNHW EEEEEEECCCCCCHH	17.29	24275569
137	Phosphorylation	GLLVLDYSKDYNHWL EEEEEECCCCCCHHH	20.79	25159151
138	Acetylation	LLVLDYSKDYNHWLA EEEEECCCCCCHHHH	58.99	23954790
140	Phosphorylation	VLDYSKDYNHWLATK EEECCCCCCHHHHCC	16.80	22817900
143	Phosphorylation	YSKDYNHWLATKSLG CCCCCCHHHHCCHHH	5.53	-
144	Acetylation	SKDYNHWLATKSLGQ CCCCCHHHHCCHHHH	3.18	-
146	Phosphorylation	DYNHWLATKSLGQWL CCCHHHHCCHHHHHH	20.99	-
148	Phosphorylation	NHWLATKSLGQWLQE CHHHHCCHHHHHHHH	33.12	20873877
153	Ubiquitination	TKSLGQWLQEEKVPA CCHHHHHHHHCCCCC	3.36	-
154	Phosphorylation	KSLGQWLQEEKVPAI CHHHHHHHHCCCCCE	54.57	-
157	Acetylation	GQWLQEEKVPAIYGV HHHHHHCCCCCEEEC	53.41	23954790
157	Succinylation	GQWLQEEKVPAIYGV HHHHHHCCCCCEEEC	53.41	-
157	Succinylation	GQWLQEEKVPAIYGV HHHHHHCCCCCEEEC	53.41	-
157	Ubiquitination	GQWLQEEKVPAIYGV HHHHHHCCCCCEEEC	53.41	-
162	Phosphorylation	EEKVPAIYGVDTRML HCCCCCEEECCHHHH	17.13	25159151
163	Acetylation	EKVPAIYGVDTRMLT CCCCCEEECCHHHHH	12.52	-
163	Ubiquitination	EKVPAIYGVDTRMLT CCCCCEEECCHHHHH	12.52	-
168	Phosphorylation	IYGVDTRMLTKIIRD EEECCHHHHHHHHHC	6.39	-
171	Acetylation	VDTRMLTKIIRDKGT CCHHHHHHHHHCCCC	31.97	26051181
171	Glutarylation	VDTRMLTKIIRDKGT CCHHHHHHHHHCCCC	31.97	24703693
176	Glutarylation	LTKIIRDKGTMLGKI HHHHHHCCCCEEEEE	46.57	24703693
177	Ubiquitination	TKIIRDKGTMLGKIE HHHHHCCCCEEEEEE	22.20	-
182	Acetylation	DKGTMLGKIEFEGQP CCCCEEEEEEECCEE	34.79	23954790
182	Ubiquitination	DKGTMLGKIEFEGQP CCCCEEEEEEECCEE	34.79	-
188	Acetylation	GKIEFEGQPVDFVDP EEEEECCEECCEECC	27.87	-
188	Ubiquitination	GKIEFEGQPVDFVDP EEEEECCEECCEECC	27.87	-
197	Acetylation	VDFVDPNKQNLIAEV CCEECCCCCCEEEEE	46.05	23954790
203	Acetylation	NKQNLIAEVSTKDVK CCCCEEEEEECCCEE	29.97	-
203	Ubiquitination	NKQNLIAEVSTKDVK CCCCEEEEEECCCEE	29.97	-
207	Acetylation	LIAEVSTKDVKVYGK EEEEEECCCEEEECC	53.68	26051181
207	Glutarylation	LIAEVSTKDVKVYGK EEEEEECCCEEEECC	53.68	24703693
207	Succinylation	LIAEVSTKDVKVYGK EEEEEECCCEEEECC	53.68	-
207	Succinylation	LIAEVSTKDVKVYGK EEEEEECCCEEEECC	53.68	23954790
207	Ubiquitination	LIAEVSTKDVKVYGK EEEEEECCCEEEECC	53.68	-
210	Acetylation	EVSTKDVKVYGKGNP EEECCCEEEECCCCC	39.61	-
210	Glutarylation	EVSTKDVKVYGKGNP EEECCCEEEECCCCC	39.61	24703693
210	Succinylation	EVSTKDVKVYGKGNP EEECCCEEEECCCCC	39.61	23954790
213	Acetylation	TKDVKVYGKGNPTKV CCCEEEECCCCCCCE	34.09	-
213	Ubiquitination	TKDVKVYGKGNPTKV CCCEEEECCCCCCCE	34.09	-
214	Acetylation	KDVKVYGKGNPTKVV CCEEEECCCCCCCEE	37.52	-
214	Glutarylation	KDVKVYGKGNPTKVV CCEEEECCCCCCCEE	37.52	24703693
214	Succinylation	KDVKVYGKGNPTKVV CCEEEECCCCCCCEE	37.52	-
214	Succinylation	KDVKVYGKGNPTKVV CCEEEECCCCCCCEE	37.52	27452117
219	Acetylation	YGKGNPTKVVAVDCG ECCCCCCCEEEEECC	35.65	26051181
219	Glutarylation	YGKGNPTKVVAVDCG ECCCCCCCEEEEECC	35.65	24703693
219	Succinylation	YGKGNPTKVVAVDCG ECCCCCCCEEEEECC	35.65	27452117
220	Ubiquitination	GKGNPTKVVAVDCGI CCCCCCCEEEEECCC	3.53	-
225	Acetylation	TKVVAVDCGIKNNVI CCEEEEECCCCCHHH	4.95	-
225	Ubiquitination	TKVVAVDCGIKNNVI CCEEEEECCCCCHHH	4.95	-
228	Acetylation	VAVDCGIKNNVIRLL EEEECCCCCHHHHHH	27.96	26051181
228	Glutarylation	VAVDCGIKNNVIRLL EEEECCCCCHHHHHH	27.96	24703693
234	Ubiquitination	IKNNVIRLLVKRGAE CCCHHHHHHHHCCCE	4.42	-
237	Glutarylation	NVIRLLVKRGAEVHL HHHHHHHHCCCEEEE	45.12	24703693
280	Acetylation	PLIQNVRKILESDRK HHHHHHHHHHHCCCC	47.57	-
280	Glutarylation	PLIQNVRKILESDRK HHHHHHHHHHHCCCC	47.57	24703693
284	Phosphorylation	NVRKILESDRKEPLF HHHHHHHCCCCCCCC	38.99	20068231
286	Ubiquitination	RKILESDRKEPLFGI HHHHHCCCCCCCCEE	55.29	-
287	Acetylation	KILESDRKEPLFGIS HHHHCCCCCCCCEEC	69.54	26051181
287	Succinylation	KILESDRKEPLFGIS HHHHCCCCCCCCEEC	69.54	-
287	Succinylation	KILESDRKEPLFGIS HHHHCCCCCCCCEEC	69.54	-
290	Phosphorylation	ESDRKEPLFGISTGN HCCCCCCCCEECHHH	6.87	-
293	Acetylation	RKEPLFGISTGNLIT CCCCCCEECHHHHHH	2.33	-
293	Ubiquitination	RKEPLFGISTGNLIT CCCCCCEECHHHHHH	2.33	-
294	Phosphorylation	KEPLFGISTGNLITG CCCCCEECHHHHHHH	30.55	20068231
295	Phosphorylation	EPLFGISTGNLITGL CCCCEECHHHHHHHH	28.33	20068231
300	Phosphorylation	ISTGNLITGLAAGAK ECHHHHHHHHHHCCC	29.34	20068231
300 (in isoform 2)	Ubiquitination	-	29.34	-
301	Phosphorylation	STGNLITGLAAGAKT CHHHHHHHHHHCCCE	13.31	-
307	Acetylation	TGLAAGAKTYKMSMA HHHHHCCCEEEECCC	52.01	-
307	Glutarylation	TGLAAGAKTYKMSMA HHHHHCCCEEEECCC	52.01	24703693
307	Succinylation	TGLAAGAKTYKMSMA HHHHHCCCEEEECCC	52.01	-
307	Succinylation	TGLAAGAKTYKMSMA HHHHHCCCEEEECCC	52.01	23954790
310	Acetylation	AAGAKTYKMSMANRG HHCCCEEEECCCCCC	29.72	-
310	Glutarylation	AAGAKTYKMSMANRG HHCCCEEEECCCCCC	29.72	24703693
312	Phosphorylation	GAKTYKMSMANRGQN CCCEEEECCCCCCCC	15.59	22798277
313	Ubiquitination	AKTYKMSMANRGQNQ CCEEEECCCCCCCCC	3.24	-
326	Phosphorylation	NQPVLNITNKQAFIT CCCEEEECCCCEEEE	34.98	21601212
332	Phosphorylation	ITNKQAFITAQNHGY ECCCCEEEEEECCCE	3.32	-
334	Ubiquitination	NKQAFITAQNHGYAL CCCEEEEEECCCEEC	11.89	-
342 (in isoform 2)	Ubiquitination	-	37.59	-
356	Ubiquitination	WKPLFVNVNDQTNEG CEEEEEECCCCCCCC	7.59	-
360 (in isoform 2)	Ubiquitination	-	37.79	-
368	Phosphorylation	NEGIMHESKPFFAVQ CCCCCCCCCCEEEEE	30.83	24275569
374	Phosphorylation	ESKPFFAVQFHPEVT CCCCEEEEEECCCCC	5.44	-
380 (in isoform 2)	Ubiquitination	-	10.36	-
396	Phosphorylation	YLFDSFFSLIKKGKA HHHHHHHHHHHCCCC	27.46	24719451
400	Succinylation	SFFSLIKKGKATTIT HHHHHHHCCCCCEEE	59.66	-
400	Succinylation	SFFSLIKKGKATTIT HHHHHHHCCCCCEEE	59.66	-
402	Glutarylation	FSLIKKGKATTITSV HHHHHCCCCCEEEEE	51.98	24703693
402	Succinylation	FSLIKKGKATTITSV HHHHHCCCCCEEEEE	51.98	-
402	Succinylation	FSLIKKGKATTITSV HHHHHCCCCCEEEEE	51.98	27452117
404	Phosphorylation	LIKKGKATTITSVLP HHHCCCCCEEEEECC	23.40	20068231
405	Phosphorylation	IKKGKATTITSVLPK HHCCCCCEEEEECCC	27.41	20068231
405 (in isoform 2)	Ubiquitination	-	27.41	-
407	Phosphorylation	KGKATTITSVLPKPA CCCCCEEEEECCCCE	15.64	20068231
408	Phosphorylation	GKATTITSVLPKPAL CCCCEEEEECCCCEE	20.15	24275569
412	Acetylation	TITSVLPKPALVASR EEEEECCCCEEHHCC	38.47	26051181
412	Glutarylation	TITSVLPKPALVASR EEEEECCCCEEHHCC	38.47	24703693
412	Succinylation	TITSVLPKPALVASR EEEEECCCCEEHHCC	38.47	-
412	Succinylation	TITSVLPKPALVASR EEEEECCCCEEHHCC	38.47	-
418	Acetylation	PKPALVASRVEVSKV CCCEEHHCCEEEEEE	29.40	-
418	Phosphorylation	PKPALVASRVEVSKV CCCEEHHCCEEEEEE	29.40	20068231
418	Ubiquitination	PKPALVASRVEVSKV CCCEEHHCCEEEEEE	29.40	-
423	Phosphorylation	VASRVEVSKVLILGS HHCCEEEEEEEEECC	11.98	-
424	Phosphorylation	ASRVEVSKVLILGSG HCCEEEEEEEEECCC	46.35	-
430	Phosphorylation	SKVLILGSGGLSIGQ EEEEEECCCCCCCCC	26.66	-
436	Phosphorylation	GSGGLSIGQAGEFDY CCCCCCCCCCCCCCC	14.12	-
441 (in isoform 2)	Ubiquitination	-	11.91	-
453	Acetylation	SQAVKAMKEENVKTV HHHHHHHHHCCCEEE	67.73	-
453	Glutarylation	SQAVKAMKEENVKTV HHHHHHHHHCCCEEE	67.73	24703693
453	Succinylation	SQAVKAMKEENVKTV HHHHHHHHHCCCEEE	67.73	23954790
453	Ubiquitination	SQAVKAMKEENVKTV HHHHHHHHHCCCEEE	67.73	-
458	Acetylation	AMKEENVKTVLMNPN HHHHCCCEEEEECCC	44.49	23954790
458	Glutarylation	AMKEENVKTVLMNPN HHHHCCCEEEEECCC	44.49	24703693
458	Succinylation	AMKEENVKTVLMNPN HHHHCCCEEEEECCC	44.49	-
458	Succinylation	AMKEENVKTVLMNPN HHHHCCCEEEEECCC	44.49	-
458	Ubiquitination	AMKEENVKTVLMNPN HHHHCCCEEEEECCC	44.49	-
462	Sulfoxidation	ENVKTVLMNPNIASV CCCEEEEECCCCCEE	7.33	28183972
464	Acetylation	VKTVLMNPNIASVQT CEEEEECCCCCEEEE	21.46	-
464	Ubiquitination	VKTVLMNPNIASVQT CEEEEECCCCCEEEE	21.46	-
468	Phosphorylation	LMNPNIASVQTNEVG EECCCCCEEEECCCC	15.80	25159151
474	Phosphorylation	ASVQTNEVGLKQADT CEEEECCCCCCCCCE	13.60	-
488	Phosphorylation	TVYFLPITPQFVTEV EEEEEECCHHHHHHH	14.75	-
494	Phosphorylation	ITPQFVTEVIKAEQP CCHHHHHHHHHHCCC	36.62	-
522	Acetylation	NCGVELFKRGVLKEY HHHHHHHHCCHHHHH	61.95	26051181
522	Succinylation	NCGVELFKRGVLKEY HHHHHHHHCCHHHHH	61.95	-
522	Succinylation	NCGVELFKRGVLKEY HHHHHHHHCCHHHHH	61.95	23954790
522	Ubiquitination	NCGVELFKRGVLKEY HHHHHHHHCCHHHHH	61.95	-
527	Acetylation	LFKRGVLKEYGVKVL HHHCCHHHHHCCEEE	46.62	26051181
527	Glutarylation	LFKRGVLKEYGVKVL HHHCCHHHHHCCEEE	46.62	24703693
527	Succinylation	LFKRGVLKEYGVKVL HHHCCHHHHHCCEEE	46.62	-
527	Succinylation	LFKRGVLKEYGVKVL HHHCCHHHHHCCEEE	46.62	23954790
527	Ubiquitination	LFKRGVLKEYGVKVL HHHCCHHHHHCCEEE	46.62	-
528	Acetylation	FKRGVLKEYGVKVLG HHCCHHHHHCCEEEC	43.27	-
528	Ubiquitination	FKRGVLKEYGVKVLG HHCCHHHHHCCEEEC	43.27	-
529	Phosphorylation	KRGVLKEYGVKVLGT HCCHHHHHCCEEECC	26.15	-
532	Acetylation	VLKEYGVKVLGTSVE HHHHHCCEEECCCHH	27.64	-
532	Glutarylation	VLKEYGVKVLGTSVE HHHHHCCEEECCCHH	27.64	24703693
533	Ubiquitination	LKEYGVKVLGTSVES HHHHCCEEECCCHHH	5.76	-
537	O-linked_Glycosylation	GVKVLGTSVESIMAT CCEEECCCHHHHHHC	23.30	UniProtKB CARBOHYD
537	Phosphorylation	GVKVLGTSVESIMAT CCEEECCCHHHHHHC	23.30	21815630
540	Phosphorylation	VLGTSVESIMATEDR EECCCHHHHHHCCCH	18.60	-
543	Phosphorylation	TSVESIMATEDRQLF CCHHHHHHCCCHHHH	13.23	-
544	Phosphorylation	SVESIMATEDRQLFS CHHHHHHCCCHHHHH	22.49	19664995
547	Methylation	SIMATEDRQLFSDKL HHHHCCCHHHHHHHH	28.95	-
550	Phosphorylation	ATEDRQLFSDKLNEI HCCCHHHHHHHHHHH	7.21	-
551	Phosphorylation	TEDRQLFSDKLNEIN CCCHHHHHHHHHHHH	42.29	21601212
553	Acetylation	DRQLFSDKLNEINEK CHHHHHHHHHHHHHH	52.60	26051181
553	Glutarylation	DRQLFSDKLNEINEK CHHHHHHHHHHHHHH	52.60	24703693
553	Methylation	DRQLFSDKLNEINEK CHHHHHHHHHHHHHH	52.60	-
553	Succinylation	DRQLFSDKLNEINEK CHHHHHHHHHHHHHH	52.60	-
553	Succinylation	DRQLFSDKLNEINEK CHHHHHHHHHHHHHH	52.60	23954790
553	Ubiquitination	DRQLFSDKLNEINEK CHHHHHHHHHHHHHH	52.60	-
559	Acetylation	DKLNEINEKIAPSFA HHHHHHHHHHCCHHH	52.05	-
559	Ubiquitination	DKLNEINEKIAPSFA HHHHHHHHHHCCHHH	52.05	-
560	Acetylation	KLNEINEKIAPSFAV HHHHHHHHHCCHHHH	39.41	23954790
560	Succinylation	KLNEINEKIAPSFAV HHHHHHHHHCCHHHH	39.41	-
560	Succinylation	KLNEINEKIAPSFAV HHHHHHHHHCCHHHH	39.41	23954790
560	Ubiquitination	KLNEINEKIAPSFAV HHHHHHHHHCCHHHH	39.41	-
564	Phosphorylation	INEKIAPSFAVESIE HHHHHCCHHHHHCHH	19.47	21712546
566	Acetylation	EKIAPSFAVESIEDA HHHCCHHHHHCHHHH	14.43	-
566	Ubiquitination	EKIAPSFAVESIEDA HHHCCHHHHHCHHHH	14.43	-
569	Phosphorylation	APSFAVESIEDALKA CCHHHHHCHHHHHHH	25.36	21712546
570	Phosphorylation	PSFAVESIEDALKAA CHHHHHCHHHHHHHH	3.34	-
575	Acetylation	ESIEDALKAADTIGY HCHHHHHHHHHHCCC	43.16	-
575	Phosphorylation	ESIEDALKAADTIGY HCHHHHHHHHHHCCC	43.16	-
575	Succinylation	ESIEDALKAADTIGY HCHHHHHHHHHHCCC	43.16	-
575	Succinylation	ESIEDALKAADTIGY HCHHHHHHHHHHCCC	43.16	-
588	Phosphorylation	GYPVMIRSAYALGGL CCCHHEECHHHHCCC	18.08	29083192
590	Phosphorylation	PVMIRSAYALGGLGS CHHEECHHHHCCCCC	12.01	21253578
596	Phosphorylation	AYALGGLGSGICPNR HHHHCCCCCCCCCCH	27.40	-
600	S-nitrosocysteine	GGLGSGICPNRETLM CCCCCCCCCCHHHHH	2.52	-
600	S-nitrosylation	GGLGSGICPNRETLM CCCCCCCCCCHHHHH	2.52	22178444
607	Sulfoxidation	CPNRETLMDLSTKAF CCCHHHHHHHHHHHH	6.77	28183972
612	Acetylation	TLMDLSTKAFAMTNQ HHHHHHHHHHHHHCE	37.82	-
612	Succinylation	TLMDLSTKAFAMTNQ HHHHHHHHHHHHHCE	37.82	-
612	Succinylation	TLMDLSTKAFAMTNQ HHHHHHHHHHHHHCE	37.82	-
616	Sulfoxidation	LSTKAFAMTNQILVE HHHHHHHHHCEEEEE	2.67	28183972
630	Acetylation	EKSVTGWKEIEYEVV EECCCCCEEEEEEEE	50.59	-
630	Ubiquitination	EKSVTGWKEIEYEVV EECCCCCEEEEEEEE	50.59	-
634	Phosphorylation	TGWKEIEYEVVRDAD CCCEEEEEEEEECCC	21.49	20068231
636	Ubiquitination	WKEIEYEVVRDADDN CEEEEEEEEECCCCC	4.13	-
640	Phosphorylation	EYEVVRDADDNCVTV EEEEEECCCCCEEEE	18.58	-
656 (in isoform 2)	Ubiquitination	-	5.08	-
684	Phosphorylation	FQMLRRTSINVVRHL HHHHHHCCCHHHHHC	15.45	28258704
690	Phosphorylation	TSINVVRHLGIVGEC CCCHHHHHCEECEEC	19.46	-
706	Phosphorylation	IQFALHPTSMEYCII EEEEECCCCCCEEEE	29.92	-
712	Phosphorylation	PTSMEYCIIEVNARL CCCCCEEEEEECHHH	2.70	-
717 (in isoform 2)	Ubiquitination	-	20.97	-
722	Phosphorylation	VNARLSRSSALASKA ECHHHCCHHHHHHHC	19.31	22798277
728	Glutarylation	RSSALASKATGYPLA CHHHHHHHCCCCCHH	44.34	24703693
728	Ubiquitination	RSSALASKATGYPLA CHHHHHHHCCCCCHH	44.34	-
730	Phosphorylation	SALASKATGYPLAFI HHHHHHCCCCCHHHH	40.77	25072903
732	Phosphorylation	LASKATGYPLAFIAA HHHHCCCCCHHHHHH	7.24	25072903
732 (in isoform 2)	Ubiquitination	-	7.24	-
751	Acetylation	GIPLPEIKNVVSGKT CCCCHHHHHHHCCCC	41.87	23954790
751	Succinylation	GIPLPEIKNVVSGKT CCCCHHHHHHHCCCC	41.87	-
751	Succinylation	GIPLPEIKNVVSGKT CCCCHHHHHHHCCCC	41.87	23954790
751	Ubiquitination	GIPLPEIKNVVSGKT CCCCHHHHHHHCCCC	41.87	-
757	Acetylation	IKNVVSGKTSACFEP HHHHHCCCCCCCCCC	31.62	26051181
757	Glutarylation	IKNVVSGKTSACFEP HHHHHCCCCCCCCCC	31.62	24703693
757	Succinylation	IKNVVSGKTSACFEP HHHHHCCCCCCCCCC	31.62	-
757	Succinylation	IKNVVSGKTSACFEP HHHHHCCCCCCCCCC	31.62	-
757	Ubiquitination	IKNVVSGKTSACFEP HHHHHCCCCCCCCCC	31.62	-
763	Ubiquitination	GKTSACFEPSLDYMV CCCCCCCCCCHHEEE	33.59	-
768	Phosphorylation	CFEPSLDYMVTKIPR CCCCCHHEEEEECCC	9.97	-
772	Acetylation	SLDYMVTKIPRWDLD CHHEEEEECCCCCHH	39.02	26051181
772	Glutarylation	SLDYMVTKIPRWDLD CHHEEEEECCCCCHH	39.02	24703693
772	Methylation	SLDYMVTKIPRWDLD CHHEEEEECCCCCHH	39.02	23644510
772	Ubiquitination	SLDYMVTKIPRWDLD CHHEEEEECCCCCHH	39.02	-
778	Methylation	TKIPRWDLDRFHGTS EECCCCCHHHCCCCC	3.95	-
778	Ubiquitination	TKIPRWDLDRFHGTS EECCCCCHHHCCCCC	3.95	-
784	Phosphorylation	DLDRFHGTSSRIGSS CHHHCCCCCCCCCCC	18.24	21406692
785	Phosphorylation	LDRFHGTSSRIGSSM HHHCCCCCCCCCCCC	23.39	21406692
786	Phosphorylation	DRFHGTSSRIGSSMK HHCCCCCCCCCCCCC	27.96	21406692
790	Phosphorylation	GTSSRIGSSMKSVGE CCCCCCCCCCCCHHH	25.53	21406692
791	Phosphorylation	TSSRIGSSMKSVGEV CCCCCCCCCCCHHHH	25.64	21406692
793	Acetylation	SRIGSSMKSVGEVMA CCCCCCCCCHHHHHH	43.89	-
793	Glutarylation	SRIGSSMKSVGEVMA CCCCCCCCCHHHHHH	43.89	24703693
793	Succinylation	SRIGSSMKSVGEVMA CCCCCCCCCHHHHHH	43.89	-
793	Succinylation	SRIGSSMKSVGEVMA CCCCCCCCCHHHHHH	43.89	-
793	Ubiquitination	SRIGSSMKSVGEVMA CCCCCCCCCHHHHHH	43.89	-
794	Phosphorylation	RIGSSMKSVGEVMAI CCCCCCCCHHHHHHH	27.06	25159151
799	Ubiquitination	MKSVGEVMAIGRTFE CCCHHHHHHHCCHHH	1.63	-
800	Phosphorylation	KSVGEVMAIGRTFEE CCHHHHHHHCCHHHH	13.27	-
811	Acetylation	TFEESFQKALRMCHP HHHHHHHHHHHHHCC	47.59	26051181
811	Glutarylation	TFEESFQKALRMCHP HHHHHHHHHHHHHCC	47.59	24703693
811	Succinylation	TFEESFQKALRMCHP HHHHHHHHHHHHHCC	47.59	23954790
811	Ubiquitination	TFEESFQKALRMCHP HHHHHHHHHHHHHCC	47.59	-
817	Ubiquitination	QKALRMCHPSIEGFT HHHHHHHCCCCCCCC	15.14	-
818 (in isoform 2)	Ubiquitination	-	31.88	-
819	Phosphorylation	ALRMCHPSIEGFTPR HHHHHCCCCCCCCCC	15.03	22798277
831	Acetylation	TPRLPMNKEWPSNLD CCCCCCCCCCCCCCC	55.70	26051181
831	Succinylation	TPRLPMNKEWPSNLD CCCCCCCCCCCCCCC	55.70	-
831	Succinylation	TPRLPMNKEWPSNLD CCCCCCCCCCCCCCC	55.70	23954790
831	Ubiquitination	TPRLPMNKEWPSNLD CCCCCCCCCCCCCCC	55.70	-
835	Phosphorylation	PMNKEWPSNLDLRKE CCCCCCCCCCCHHHH	51.61	26657352
837	Acetylation	NKEWPSNLDLRKELS CCCCCCCCCHHHHHC	8.44	-
837	Ubiquitination	NKEWPSNLDLRKELS CCCCCCCCCHHHHHC	8.44	-
841	Acetylation	PSNLDLRKELSEPSS CCCCCHHHHHCCCCH	71.01	-
841	Glutarylation	PSNLDLRKELSEPSS CCCCCHHHHHCCCCH	71.01	24703693
841	Phosphorylation	PSNLDLRKELSEPSS CCCCCHHHHHCCCCH	71.01	-
841	Succinylation	PSNLDLRKELSEPSS CCCCCHHHHHCCCCH	71.01	23954790
844	Phosphorylation	LDLRKELSEPSSTRI CCHHHHHCCCCHHHH	48.86	25627689
847	Ubiquitination	RKELSEPSSTRIYAI HHHHCCCCHHHHHHH	40.05	-
848	Phosphorylation	KELSEPSSTRIYAIA HHHCCCCHHHHHHHH	32.21	25627689
849	Phosphorylation	ELSEPSSTRIYAIAK HHCCCCHHHHHHHHH	25.98	24275569
856	Acetylation	TRIYAIAKAIDDNMS HHHHHHHHHHCCCCC	39.50	23954790
856	Glutarylation	TRIYAIAKAIDDNMS HHHHHHHHHHCCCCC	39.50	24703693
856	Ubiquitination	TRIYAIAKAIDDNMS HHHHHHHHHHCCCCC	39.50	-
862	Acetylation	AKAIDDNMSLDEIEK HHHHCCCCCHHHHHH	5.60	-
862	Sulfoxidation	AKAIDDNMSLDEIEK HHHHCCCCCHHHHHH	5.60	28183972
862	Ubiquitination	AKAIDDNMSLDEIEK HHHHCCCCCHHHHHH	5.60	-
863	Phosphorylation	KAIDDNMSLDEIEKL HHHCCCCCHHHHHHH	38.63	20873877
869	Acetylation	MSLDEIEKLTYIDKW CCHHHHHHHHHHHHH	52.36	23954790
869	Glutarylation	MSLDEIEKLTYIDKW CCHHHHHHHHHHHHH	52.36	24703693
869	Phosphorylation	MSLDEIEKLTYIDKW CCHHHHHHHHHHHHH	52.36	-
869	Succinylation	MSLDEIEKLTYIDKW CCHHHHHHHHHHHHH	52.36	23954790
872	Phosphorylation	DEIEKLTYIDKWFLY HHHHHHHHHHHHHHH	19.98	-
875	Acetylation	EKLTYIDKWFLYKMR HHHHHHHHHHHHHHH	30.22	23954790
875	Glutarylation	EKLTYIDKWFLYKMR HHHHHHHHHHHHHHH	30.22	24703693
875	Succinylation	EKLTYIDKWFLYKMR HHHHHHHHHHHHHHH	30.22	-
875	Succinylation	EKLTYIDKWFLYKMR HHHHHHHHHHHHHHH	30.22	-
875	Ubiquitination	EKLTYIDKWFLYKMR HHHHHHHHHHHHHHH	30.22	-
879	Phosphorylation	YIDKWFLYKMRDILN HHHHHHHHHHHHHHC	8.02	-
881	Acetylation	DKWFLYKMRDILNME HHHHHHHHHHHHCHH	2.69	-
889	Acetylation	RDILNMEKTLKGLNS HHHHCHHHHHCCCCC	48.68	-
889	Glutarylation	RDILNMEKTLKGLNS HHHHCHHHHHCCCCC	48.68	24703693
889	Succinylation	RDILNMEKTLKGLNS HHHHCHHHHHCCCCC	48.68	-
889	Succinylation	RDILNMEKTLKGLNS HHHHCHHHHHCCCCC	48.68	-
892	Acetylation	LNMEKTLKGLNSESM HCHHHHHCCCCCCCC	67.59	23954790
892	Glutarylation	LNMEKTLKGLNSESM HCHHHHHCCCCCCCC	67.59	24703693
892	Succinylation	LNMEKTLKGLNSESM HCHHHHHCCCCCCCC	67.59	-
892	Succinylation	LNMEKTLKGLNSESM HCHHHHHCCCCCCCC	67.59	27452117
892	Ubiquitination	LNMEKTLKGLNSESM HCHHHHHCCCCCCCC	67.59	-
895	Ubiquitination	EKTLKGLNSESMTEE HHHHCCCCCCCCCHH	53.02	-
896	Phosphorylation	KTLKGLNSESMTEET HHHCCCCCCCCCHHH	35.77	20068231
898	Acetylation	LKGLNSESMTEETLK HCCCCCCCCCHHHHH	30.72	-
898	Phosphorylation	LKGLNSESMTEETLK HCCCCCCCCCHHHHH	30.72	21815630
898	Ubiquitination	LKGLNSESMTEETLK HCCCCCCCCCHHHHH	30.72	-
899	Sulfoxidation	KGLNSESMTEETLKR CCCCCCCCCHHHHHH	4.86	28183972
900	Phosphorylation	GLNSESMTEETLKRA CCCCCCCCHHHHHHH	39.69	20068231
902	Phosphorylation	NSESMTEETLKRAKE CCCCCCHHHHHHHHH	50.72	-
903	Phosphorylation	SESMTEETLKRAKEI CCCCCHHHHHHHHHH	31.20	20068231
904	Phosphorylation	ESMTEETLKRAKEIG CCCCHHHHHHHHHHC	3.90	-
905	Acetylation	SMTEETLKRAKEIGF CCCHHHHHHHHHHCC	58.70	26051181
905	Glutarylation	SMTEETLKRAKEIGF CCCHHHHHHHHHHCC	58.70	24703693
905	Succinylation	SMTEETLKRAKEIGF CCCHHHHHHHHHHCC	58.70	23954790
905 (in isoform 2)	Ubiquitination	-	58.70	-
908	Acetylation	EETLKRAKEIGFSDK HHHHHHHHHHCCCHH	54.63	-
908	Glutarylation	EETLKRAKEIGFSDK HHHHHHHHHHCCCHH	54.63	24703693
911	Acetylation	LKRAKEIGFSDKQIS HHHHHHHCCCHHHHH	19.66	-
911	Ubiquitination	LKRAKEIGFSDKQIS HHHHHHHCCCHHHHH	19.66	-
913	Phosphorylation	RAKEIGFSDKQISKC HHHHHCCCHHHHHHH	38.39	20068231
914	Ubiquitination	AKEIGFSDKQISKCL HHHHCCCHHHHHHHH	44.62	-
915	Acetylation	KEIGFSDKQISKCLG HHHCCCHHHHHHHHC	48.62	26051181
915	Glutarylation	KEIGFSDKQISKCLG HHHCCCHHHHHHHHC	48.62	24703693
915	Succinylation	KEIGFSDKQISKCLG HHHCCCHHHHHHHHC	48.62	-
915	Succinylation	KEIGFSDKQISKCLG HHHCCCHHHHHHHHC	48.62	-
918	Phosphorylation	GFSDKQISKCLGLTE CCCHHHHHHHHCCCH	18.15	-
919	Acetylation	FSDKQISKCLGLTEA CCHHHHHHHHCCCHH	34.80	26051181
919	Glutarylation	FSDKQISKCLGLTEA CCHHHHHHHHCCCHH	34.80	24703693
919	Phosphorylation	FSDKQISKCLGLTEA CCHHHHHHHHCCCHH	34.80	-
919	Succinylation	FSDKQISKCLGLTEA CCHHHHHHHHCCCHH	34.80	-
919	Succinylation	FSDKQISKCLGLTEA CCHHHHHHHHCCCHH	34.80	27452117
921	Acetylation	DKQISKCLGLTEAQT HHHHHHHHCCCHHHH	7.87	-
921	Ubiquitination	DKQISKCLGLTEAQT HHHHHHHHCCCHHHH	7.87	-
924	Phosphorylation	ISKCLGLTEAQTREL HHHHHCCCHHHHHHH	27.72	-
925	Acetylation	SKCLGLTEAQTRELR HHHHCCCHHHHHHHH	43.77	-
925	Ubiquitination	SKCLGLTEAQTRELR HHHHCCCHHHHHHHH	43.77	-
935	Acetylation	TRELRLKKNIHPWVK HHHHHHHCCCCHHHH	66.77	-
941	Ubiquitination	KKNIHPWVKQIDTLA HCCCCHHHHHHHHHH	3.73	-
1015	Ubiquitination	KKTVVVNCNPETVST CEEEEEECCCCCCCC	6.42	-
1019	Phosphorylation	VVNCNPETVSTDFDE EEECCCCCCCCCHHH	22.48	25627689
1020 (in isoform 2)	Ubiquitination	-	5.75	-
1021	Phosphorylation	NCNPETVSTDFDECD ECCCCCCCCCHHHCC	29.67	24275569
1022	Phosphorylation	CNPETVSTDFDECDK CCCCCCCCCHHHCCH	36.03	25627689
1036	Phosphorylation	KLYFEELSLERILDI HHHHHHCCHHHHHHH	31.31	21815630
1042	Phosphorylation	LSLERILDIYHQEAC CCHHHHHHHHHHCCC	36.71	-
1055	Phosphorylation	ACGGCIISVGGQIPN CCCCEEEEECCCCCC	8.52	-
1061	Phosphorylation	ISVGGQIPNNLAVPL EEECCCCCCCCEEEE	18.77	-
1069	Phosphorylation	NNLAVPLYKNGVKIM CCCEEEEEECCEEEE	9.06	20058876
1070	Acetylation	NLAVPLYKNGVKIMG CCEEEEEECCEEEEC	55.71	156307
1074	Acetylation	PLYKNGVKIMGTSPL EEEECCEEEECCCCC	28.51	-
1074	Glutarylation	PLYKNGVKIMGTSPL EEEECCEEEECCCCC	28.51	24703693
1074	Succinylation	PLYKNGVKIMGTSPL EEEECCEEEECCCCC	28.51	-
1074	Succinylation	PLYKNGVKIMGTSPL EEEECCEEEECCCCC	28.51	-
1074	Ubiquitination	PLYKNGVKIMGTSPL EEEECCEEEECCCCC	28.51	-
1075	Phosphorylation	LYKNGVKIMGTSPLQ EEECCEEEECCCCCC	2.60	-
1076	Sulfoxidation	YKNGVKIMGTSPLQI EECCEEEECCCCCCC	3.87	28183972
1078	Phosphorylation	NGVKIMGTSPLQIDR CCEEEECCCCCCCCC	15.14	23403867
1079	Phosphorylation	GVKIMGTSPLQIDRA CEEEECCCCCCCCCH	20.20	25159151
1080	Ubiquitination	VKIMGTSPLQIDRAE EEEECCCCCCCCCHH	28.28	-
1084	Phosphorylation	GTSPLQIDRAEDRSI CCCCCCCCCHHHHCH	30.67	-
1085	Phosphorylation	TSPLQIDRAEDRSIF CCCCCCCCHHHHCHH	41.32	-
1090	Phosphorylation	IDRAEDRSIFSAVLD CCCHHHHCHHHHHHH	40.06	21712546
1093	Phosphorylation	AEDRSIFSAVLDELK HHHHCHHHHHHHHHH	18.79	-
1096	Phosphorylation	RSIFSAVLDELKVAQ HCHHHHHHHHHHHCC	4.18	-
1100	Acetylation	SAVLDELKVAQAPWK HHHHHHHHHCCCCHH	33.21	-
1100	Succinylation	SAVLDELKVAQAPWK HHHHHHHHHCCCCHH	33.21	-
1100	Succinylation	SAVLDELKVAQAPWK HHHHHHHHHCCCCHH	33.21	-
1100	Ubiquitination	SAVLDELKVAQAPWK HHHHHHHHHCCCCHH	33.21	-
1106	Ubiquitination	LKVAQAPWKAVNTLN HHHCCCCHHHHHHHH	12.31	-
1107	Acetylation	KVAQAPWKAVNTLNE HHCCCCHHHHHHHHH	41.20	23954790
1107	Succinylation	KVAQAPWKAVNTLNE HHCCCCHHHHHHHHH	41.20	23954790
1107	Ubiquitination	KVAQAPWKAVNTLNE HHCCCCHHHHHHHHH	41.20	-
1113	Acetylation	WKAVNTLNEALEFAK HHHHHHHHHHHHHHH	30.38	-
1113	Ubiquitination	WKAVNTLNEALEFAK HHHHHHHHHHHHHHH	30.38	-
1126	Ubiquitination	AKSVDYPCLLRPSYV HHCCCCCEECCCCEE	4.56	-
1131	Phosphorylation	YPCLLRPSYVLSGSA CCEECCCCEEECCCH	22.80	20068231
1132	Phosphorylation	PCLLRPSYVLSGSAM CEECCCCEEECCCHH	14.21	20068231
1135	Phosphorylation	LRPSYVLSGSAMNVV CCCCEEECCCHHEEE	22.21	20068231
1137	Phosphorylation	PSYVLSGSAMNVVFS CCEEECCCHHEEEEC	22.44	20068231
1141	Phosphorylation	LSGSAMNVVFSEDEM ECCCHHEEEECHHHH	2.71	-
1144	Phosphorylation	SAMNVVFSEDEMKKF CHHEEEECHHHHHHH	32.31	20068231
1149	Acetylation	VFSEDEMKKFLEEAT EECHHHHHHHHHHHH	38.02	24884125
1149	Succinylation	VFSEDEMKKFLEEAT EECHHHHHHHHHHHH	38.02	-
1149	Succinylation	VFSEDEMKKFLEEAT EECHHHHHHHHHHHH	38.02	-
1150	Acetylation	FSEDEMKKFLEEATR ECHHHHHHHHHHHHH	54.60	27178108
1150	Glutarylation	FSEDEMKKFLEEATR ECHHHHHHHHHHHHH	54.60	24703693
1150	Succinylation	FSEDEMKKFLEEATR ECHHHHHHHHHHHHH	54.60	27452117
1156	Phosphorylation	KKFLEEATRVSQEHP HHHHHHHHHHCCCCC	34.58	24275569
1156	Ubiquitination	KKFLEEATRVSQEHP HHHHHHHHHHCCCCC	34.58	-
1159	Phosphorylation	LEEATRVSQEHPVVL HHHHHHHCCCCCEEE	26.93	25159151
1165	Phosphorylation	VSQEHPVVLTKFVEG HCCCCCEEEEEECCC	7.09	-
1168	Acetylation	EHPVVLTKFVEGARE CCCEEEEEECCCCCE	43.16	27452117
1168	Glutarylation	EHPVVLTKFVEGARE CCCEEEEEECCCCCE	43.16	24703693
1168	Succinylation	EHPVVLTKFVEGARE CCCEEEEEECCCCCE	43.16	-
1168	Succinylation	EHPVVLTKFVEGARE CCCEEEEEECCCCCE	43.16	27452117
1168	Ubiquitination	EHPVVLTKFVEGARE CCCEEEEEECCCCCE	43.16	-
1174	Ubiquitination	TKFVEGAREVEMDAV EEECCCCCEEECCCC	60.39	-
1183	Acetylation	VEMDAVGKDGRVISH EECCCCCCCCCHHHH	50.87	23954790
1183	Glutarylation	VEMDAVGKDGRVISH EECCCCCCCCCHHHH	50.87	24703693
1183	Succinylation	VEMDAVGKDGRVISH EECCCCCCCCCHHHH	50.87	-
1183	Succinylation	VEMDAVGKDGRVISH EECCCCCCCCCHHHH	50.87	23954790
1183	Ubiquitination	VEMDAVGKDGRVISH EECCCCCCCCCHHHH	50.87	-
1189	Acetylation	GKDGRVISHAISEHV CCCCCHHHHHHHHHH	12.19	-
1189	Ubiquitination	GKDGRVISHAISEHV CCCCCHHHHHHHHHH	12.19	-
1203	Phosphorylation	VEDAGVHSGDATLML HHHCCCCCCCCEEEE	35.64	28258704
1209	Phosphorylation	HSGDATLMLPTQTIS CCCCCEEEEECCEEC	3.51	-
1214	Phosphorylation	TLMLPTQTISQGAIE EEEEECCEECHHHHH	25.69	24275569
1222	Acetylation	ISQGAIEKVKDATRK ECHHHHHHHHHHHHH	48.77	-
1222	Ubiquitination	ISQGAIEKVKDATRK ECHHHHHHHHHHHHH	48.77	-
1224	Glutarylation	QGAIEKVKDATRKIA HHHHHHHHHHHHHHH	53.35	24703693
1228	Ubiquitination	EKVKDATRKIAKAFA HHHHHHHHHHHHHHH	30.06	-
1232	Acetylation	DATRKIAKAFAISGP HHHHHHHHHHHHCCC	47.73	-
1232	Succinylation	DATRKIAKAFAISGP HHHHHHHHHHHHCCC	47.73	-
1232	Succinylation	DATRKIAKAFAISGP HHHHHHHHHHHHCCC	47.73	-
1261	Phosphorylation	IECNLRASRSFPFVS EEEECCCCCCCCCCC	23.25	-
1268	Phosphorylation	SRSFPFVSKTLGVDF CCCCCCCCCCCCCCE	21.94	21601212
1269	Acetylation	RSFPFVSKTLGVDFI CCCCCCCCCCCCCEE	42.33	-
1269	Succinylation	RSFPFVSKTLGVDFI CCCCCCCCCCCCCEE	42.33	-
1269	Succinylation	RSFPFVSKTLGVDFI CCCCCCCCCCCCCEE	42.33	-
1269	Ubiquitination	RSFPFVSKTLGVDFI CCCCCCCCCCCCCEE	42.33	-
1270	Phosphorylation	SFPFVSKTLGVDFID CCCCCCCCCCCCEEE	22.65	21712546
1274	Phosphorylation	VSKTLGVDFIDVATK CCCCCCCCEEEECCH	32.74	-
1275	Ubiquitination	SKTLGVDFIDVATKV CCCCCCCEEEECCHH	4.83	-
1276	Phosphorylation	KTLGVDFIDVATKVM CCCCCCEEEECCHHH	3.44	-
1280	Phosphorylation	VDFIDVATKVMIGEN CCEEEECCHHHHCCC	24.82	21712546
1286	Phosphorylation	ATKVMIGENVDEKHL CCHHHHCCCCCCCCC	43.06	-
1287	Ubiquitination	TKVMIGENVDEKHLP CHHHHCCCCCCCCCC	41.13	-
1291	Acetylation	IGENVDEKHLPTLDH HCCCCCCCCCCCCCC	46.08	23954790
1291	Succinylation	IGENVDEKHLPTLDH HCCCCCCCCCCCCCC	46.08	-
1291	Succinylation	IGENVDEKHLPTLDH HCCCCCCCCCCCCCC	46.08	-
1295	Phosphorylation	VDEKHLPTLDHPIIP CCCCCCCCCCCCCCC	51.70	-
1297	Acetylation	EKHLPTLDHPIIPAD CCCCCCCCCCCCCCC	48.25	-
1297	Ubiquitination	EKHLPTLDHPIIPAD CCCCCCCCCCCCCCC	48.25	-
1305	Phosphorylation	HPIIPADYVAIKAPM CCCCCCCCEEEECCC	8.22	25159151
1309	Ubiquitination	PADYVAIKAPMFSWP CCCCEEEECCCCCCC	36.38	-
1311	Phosphorylation	DYVAIKAPMFSWPRL CCEEEECCCCCCCCC	21.25	27642862
1314	Phosphorylation	AIKAPMFSWPRLRDA EEECCCCCCCCCCCC	29.89	24719451
1315	Ubiquitination	IKAPMFSWPRLRDAD EECCCCCCCCCCCCC	3.19	-
1331	O-linked_Glycosylation	ILRCEMASTGEVACF CEEEEECCCCCEEEC	35.32	UniProtKB CARBOHYD
1331	Phosphorylation	ILRCEMASTGEVACF CEEEEECCCCCEEEC	35.32	-
1332	O-linked_Glycosylation	LRCEMASTGEVACFG EEEEECCCCCEEECC	28.02	UniProtKB CARBOHYD
1332	Phosphorylation	LRCEMASTGEVACFG EEEEECCCCCEEECC	28.02	-
1337	Phosphorylation	ASTGEVACFGEGIHT CCCCCEEECCCCHHH	5.63	-
1338	Phosphorylation	STGEVACFGEGIHTA CCCCEEECCCCHHHH	7.81	-
1350	Sulfoxidation	HTAFLKAMLSTGFKI HHHHHHHHHHCCCCC	2.65	28183972
1356	Acetylation	AMLSTGFKIPQKGIL HHHHCCCCCCCCCEE	55.62	26051181
1356	Glutarylation	AMLSTGFKIPQKGIL HHHHCCCCCCCCCEE	55.62	24703693
1356	Succinylation	AMLSTGFKIPQKGIL HHHHCCCCCCCCCEE	55.62	-
1356	Succinylation	AMLSTGFKIPQKGIL HHHHCCCCCCCCCEE	55.62	27452117
1356	Ubiquitination	AMLSTGFKIPQKGIL HHHHCCCCCCCCCEE	55.62	-
1360	Glutarylation	TGFKIPQKGILIGIQ CCCCCCCCCEEEEEC	42.43	24703693
1360	Succinylation	TGFKIPQKGILIGIQ CCCCCCCCCEEEEEC	42.43	-
1360	Succinylation	TGFKIPQKGILIGIQ CCCCCCCCCEEEEEC	42.43	-
1360	Ubiquitination	TGFKIPQKGILIGIQ CCCCCCCCCEEEEEC	42.43	-
1362	Acetylation	FKIPQKGILIGIQQS CCCCCCCEEEEECCC	3.06	-
1362	Ubiquitination	FKIPQKGILIGIQQS CCCCCCCEEEEECCC	3.06	-
1419	Phosphorylation	SQEGQNPSLSSIRKL CCCCCCCCHHHHHHH	48.73	26546556
1421	Phosphorylation	EGQNPSLSSIRKLIR CCCCCCHHHHHHHHH	28.23	30301811
1422	Phosphorylation	GQNPSLSSIRKLIRD CCCCCHHHHHHHHHC	31.54	25954137
1425	Phosphorylation	PSLSSIRKLIRDGSI CCHHHHHHHHHCCCC	46.74	-
1431	Phosphorylation	RKLIRDGSIDLVINL HHHHHCCCCCEEEEC	19.74	26657352
1437	Phosphorylation	GSIDLVINLPNNNTK CCCCEEEECCCCCCC	41.80	-
1444	Acetylation	NLPNNNTKFVHDNYV ECCCCCCCEEECCEE	47.73	26051181
1444	Succinylation	NLPNNNTKFVHDNYV ECCCCCCCEEECCEE	47.73	-
1444	Succinylation	NLPNNNTKFVHDNYV ECCCCCCCEEECCEE	47.73	-
1444	Ubiquitination	NLPNNNTKFVHDNYV ECCCCCCCEEECCEE	47.73	-
1450	Phosphorylation	TKFVHDNYVIRRTAV CCEEECCEEEEEHHH	11.87	21253578
1455	Phosphorylation	DNYVIRRTAVDSGIP CCEEEEEHHHCCCCC	22.60	21712546
1456	Phosphorylation	NYVIRRTAVDSGIPL CEEEEEHHHCCCCCC	10.99	-
1459	Phosphorylation	IRRTAVDSGIPLLTN EEEHHHCCCCCCCCC	31.83	29083192
1461	Phosphorylation	RTAVDSGIPLLTNFQ EHHHCCCCCCCCCHH	2.22	-
1465	Phosphorylation	DSGIPLLTNFQVTKL CCCCCCCCCHHHHHH	41.49	29083192
1470	Phosphorylation	LLTNFQVTKLFAEAV CCCCHHHHHHHHHHH	15.96	29083192
1471	Acetylation	LTNFQVTKLFAEAVQ CCCHHHHHHHHHHHH	42.63	-
1471	Succinylation	LTNFQVTKLFAEAVQ CCCHHHHHHHHHHHH	42.63	-
1471	Succinylation	LTNFQVTKLFAEAVQ CCCHHHHHHHHHHHH	42.63	23954790
1471	Ubiquitination	LTNFQVTKLFAEAVQ CCCHHHHHHHHHHHH	42.63	-
1477	Ubiquitination	TKLFAEAVQKSRKVD HHHHHHHHHHHCCCC	5.76	-
1479	Acetylation	LFAEAVQKSRKVDSK HHHHHHHHHCCCCCH	45.70	26051181
1479	Glutarylation	LFAEAVQKSRKVDSK HHHHHHHHHCCCCCH	45.70	24703693
1479	Succinylation	LFAEAVQKSRKVDSK HHHHHHHHHCCCCCH	45.70	-
1479	Succinylation	LFAEAVQKSRKVDSK HHHHHHHHHCCCCCH	45.70	27452117
1485	Ubiquitination	QKSRKVDSKSLFHYR HHHCCCCCHHHHCHH	27.42	-
1486	Acetylation	KSRKVDSKSLFHYRQ HHCCCCCHHHHCHHH	46.87	26051181
1486	Glutarylation	KSRKVDSKSLFHYRQ HHCCCCCHHHHCHHH	46.87	24703693
1486	Succinylation	KSRKVDSKSLFHYRQ HHCCCCCHHHHCHHH	46.87	-
1486	Succinylation	KSRKVDSKSLFHYRQ HHCCCCCHHHHCHHH	46.87	23954790
1487	Phosphorylation	SRKVDSKSLFHYRQY HCCCCCHHHHCHHHH	39.97	28555341
1491	Phosphorylation	DSKSLFHYRQYSAGK CCHHHHCHHHHCCCC	7.65	-
1492	Acetylation	SKSLFHYRQYSAGKA CHHHHCHHHHCCCCC	22.01	-
1492	Ubiquitination	SKSLFHYRQYSAGKA CHHHHCHHHHCCCCC	22.01	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CPSM_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Reference
55	K	Glutarylation	24703693
Deglutarylated by SIRT5 at Lys-55, Lys-219, Lys-412, Lys-889, Lys-892, Lys-915, Lys-1360 and Lys-1486, leading to activation.
219	K	Glutarylation	24703693
Deglutarylated by SIRT5 at Lys-55, Lys-219, Lys-412, Lys-889, Lys-892, Lys-915, Lys-1360 and Lys-1486, leading to activation.
287	K	Succinylation	-
Succinylated at Lys-287 and Lys-1291.
412	K	Glutarylation	24703693
Deglutarylated by SIRT5 at Lys-55, Lys-219, Lys-412, Lys-889, Lys-892, Lys-915, Lys-1360 and Lys-1486, leading to activation.
889	K	Glutarylation	24703693
Deglutarylated by SIRT5 at Lys-55, Lys-219, Lys-412, Lys-889, Lys-892, Lys-915, Lys-1360 and Lys-1486, leading to activation.
892	K	Glutarylation	24703693
Deglutarylated by SIRT5 at Lys-55, Lys-219, Lys-412, Lys-889, Lys-892, Lys-915, Lys-1360 and Lys-1486, leading to activation.
915	K	Glutarylation	24703693
Deglutarylated by SIRT5 at Lys-55, Lys-219, Lys-412, Lys-889, Lys-892, Lys-915, Lys-1360 and Lys-1486, leading to activation.
1291	K	Succinylation	-
Desuccinylated at Lys-1291 by SIRT5, leading to activation (By similarity).
1291	K	Succinylation	-
Succinylated at Lys-287 and Lys-1291.
1360	K	Glutarylation	24703693
Deglutarylated by SIRT5 at Lys-55, Lys-219, Lys-412, Lys-889, Lys-892, Lys-915, Lys-1360 and Lys-1486, leading to activation.
1486	K	Glutarylation	24703693
Deglutarylated by SIRT5 at Lys-55, Lys-219, Lys-412, Lys-889, Lys-892, Lys-915, Lys-1360 and Lys-1486, leading to activation.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CPSM_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FUMH_HUMAN	FH	physical	22939629
SC22B_HUMAN	SEC22B	physical	22939629
CPT1A_HUMAN	CPT1A	physical	22939629
RT26_HUMAN	MRPS26	physical	22939629
GRP75_HUMAN	HSPA9	physical	22939629
LPPRC_HUMAN	LRPPRC	physical	22939629
TOM70_HUMAN	TOMM70A	physical	22939629
PCBP1_HUMAN	PCBP1	physical	22939629
HNRH1_HUMAN	HNRNPH1	physical	26344197
HSP74_HUMAN	HSPA4	physical	26344197
HSP7C_HUMAN	HSPA8	physical	26344197
HS105_HUMAN	HSPH1	physical	26344197
UBC_HUMAN	UBC	physical	27425868
K2C1_HUMAN	KRT1	physical	27425868
ALBU_HUMAN	ALB	physical	27425868

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
237300	Carbamoyl phosphate synthetase 1 deficiency (CPS1D)
615371	Pulmonary hypertension, neonatal (PHN)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
DB06775	Carglumic Acid

Regulatory Network of CPSM_HUMAN

Related Literatures of Post-Translational Modification

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