OAT_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OAT_MOUSE
• UniProt AC: P29758
• Protein Name: Ornithine aminotransferase, mitochondrial
• Gene Name: Oat
• Organism: Mus musculus (Mouse).
• Sequence Length: 439
• Subcellular Localization: Mitochondrion matrix .
• Protein Sequence: MLSKLASLQTIAALRRGVHTSVASATSVATKKTEQGPPSSEYIFERESKYGAHNYHPLPVALERGKGIYMWDVEGRQYFDFLSAYGAVSQGHCHPKIIDAMKSQVDKLTLTSRAFYNNVLGEYEEYITKLFNYNKVLPMNTGVEAGETACKLARRWGYTVKGIQKYKAKIVFADGNFWGRTLSAISSSTDPTSYDGFGPFMPGFETIPYNDLPALERALQDPNVAAFMVEPIQGEAGVIVPDPGYLTGVRELCTRHQVLFIADEIQTGLARTGRWLAVDHENVRPDMVLLGKALSGGLYPVSAVLCDDEIMLTIKPGEHGSTYGGNPLGCRIAIAALEVLEEENLAENADKMGAILRKELMKLPSDVVTSVRGKGLLNAIVIRETKDCDAWKVCLRLRDNGLLAKPTHGDIIRLAPPLVIKEDEIRESVEIINKTILSF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	Acetylation	ATSVATKKTEQGPPS HCCCCCCCCCCCCCC	53.60	23576753
42	Phosphorylation	QGPPSSEYIFERESK CCCCCHHHEEECCCC	16.92	29899451
49	Acetylation	YIFERESKYGAHNYH HEEECCCCCCCCCCC	42.84	23576753
50	Phosphorylation	IFERESKYGAHNYHP EEECCCCCCCCCCCC	28.91	-
55	Phosphorylation	SKYGAHNYHPLPVAL CCCCCCCCCCCEEEE	8.57	-
66	Acetylation	PVALERGKGIYMWDV EEEEECCCCEEEEEC	48.64	23576753
96	Acetylation	SQGHCHPKIIDAMKS HCCCCCHHHHHHHHH	28.73	19861831
102	Acetylation	PKIIDAMKSQVDKLT HHHHHHHHHHHCHHH	39.18	22826441
102	Succinylation	PKIIDAMKSQVDKLT HHHHHHHHHHHCHHH	39.18	-
102	Ubiquitination	PKIIDAMKSQVDKLT HHHHHHHHHHHCHHH	39.18	-
102	Succinylation	PKIIDAMKSQVDKLT HHHHHHHHHHHCHHH	39.18	23806337
107	Acetylation	AMKSQVDKLTLTSRA HHHHHHCHHHHHHHH	44.51	23576753
107	Succinylation	AMKSQVDKLTLTSRA HHHHHHCHHHHHHHH	44.51	-
107	Ubiquitination	AMKSQVDKLTLTSRA HHHHHHCHHHHHHHH	44.51	-
107	Succinylation	AMKSQVDKLTLTSRA HHHHHHCHHHHHHHH	44.51	23806337
135	Ubiquitination	TKLFNYNKVLPMNTG HHHHCCCCEECCCCC	34.49	22790023
150	S-nitrosylation	VEAGETACKLARRWG CCHHHHHHHHHHHHC	4.91	22178444
150	S-palmitoylation	VEAGETACKLARRWG CCHHHHHHHHHHHHC	4.91	28526873
150	S-nitrosocysteine	VEAGETACKLARRWG CCHHHHHHHHHHHHC	4.91	-
151	Ubiquitination	EAGETACKLARRWGY CHHHHHHHHHHHHCC	42.59	22790023
151	Acetylation	EAGETACKLARRWGY CHHHHHHHHHHHHCC	42.59	23864654
158	Phosphorylation	KLARRWGYTVKGIQK HHHHHHCCCCCCHHH	11.03	-
159	Phosphorylation	LARRWGYTVKGIQKY HHHHHCCCCCCHHHE	16.29	23140645
165	Acetylation	YTVKGIQKYKAKIVF CCCCCHHHEEEEEEE	46.96	23864654
166	Phosphorylation	TVKGIQKYKAKIVFA CCCCHHHEEEEEEEE	10.37	-
169	Ubiquitination	GIQKYKAKIVFADGN CHHHEEEEEEEECCC	34.94	-
169	Succinylation	GIQKYKAKIVFADGN CHHHEEEEEEEECCC	34.94	23954790
169	Acetylation	GIQKYKAKIVFADGN CHHHEEEEEEEECCC	34.94	22826441
292	N6-(pyridoxal phosphate)lysine	PDMVLLGKALSGGLY CCEEEHHHHHCCCCC	46.23	-
292	Other	PDMVLLGKALSGGLY CCEEEHHHHHCCCCC	46.23	-
295	Phosphorylation	VLLGKALSGGLYPVS EEHHHHHCCCCCCCE	35.36	26643407
299	Phosphorylation	KALSGGLYPVSAVLC HHHCCCCCCCEEEEE	12.59	26643407
302	Phosphorylation	SGGLYPVSAVLCDDE CCCCCCCEEEEECCE	14.25	26643407
313	Phosphorylation	CDDEIMLTIKPGEHG ECCEEEEEECCCCCC	15.02	26643407
351	Acetylation	NLAENADKMGAILRK CHHHHHHHHHHHHHH	36.50	23954790
358	Acetylation	KMGAILRKELMKLPS HHHHHHHHHHHCCCC	52.32	23201123
362	Acetylation	ILRKELMKLPSDVVT HHHHHHHCCCCCHHH	70.62	23576753
362	Succinylation	ILRKELMKLPSDVVT HHHHHHHCCCCCHHH	70.62	-
362	Ubiquitination	ILRKELMKLPSDVVT HHHHHHHCCCCCHHH	70.62	-
362	Succinylation	ILRKELMKLPSDVVT HHHHHHHCCCCCHHH	70.62	23806337
365	Phosphorylation	KELMKLPSDVVTSVR HHHHCCCCCHHHHCC	54.17	29472430
369	Phosphorylation	KLPSDVVTSVRGKGL CCCCCHHHHCCCCCC	22.73	29472430
370	Phosphorylation	LPSDVVTSVRGKGLL CCCCHHHHCCCCCCE	9.75	29472430
374	Succinylation	VVTSVRGKGLLNAIV HHHHCCCCCCEEEEE	35.50	23806337
374	Ubiquitination	VVTSVRGKGLLNAIV HHHHCCCCCCEEEEE	35.50	-
374	Acetylation	VVTSVRGKGLLNAIV HHHHCCCCCCEEEEE	35.50	23806337
386	Succinylation	AIVIRETKDCDAWKV EEEEEECCCCCHHHH	52.16	23806337
386	Acetylation	AIVIRETKDCDAWKV EEEEEECCCCCHHHH	52.16	23576753
392	Succinylation	TKDCDAWKVCLRLRD CCCCCHHHHHHHCCC	25.45	23806337
392	Acetylation	TKDCDAWKVCLRLRD CCCCCHHHHHHHCCC	25.45	23576753
405	Succinylation	RDNGLLAKPTHGDII CCCCCCCCCCCCCCC	50.87	23806337
405	Acetylation	RDNGLLAKPTHGDII CCCCCCCCCCCCCCC	50.87	23576753
405	Succinylation	RDNGLLAKPTHGDII CCCCCCCCCCCCCCC	50.87	-
421	Acetylation	LAPPLVIKEDEIRES CCCCEEECHHHHHHH	52.19	23576753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OAT_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OAT_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OAT_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of OAT_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.