dbPTM

ECHA_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ECHA_MOUSE
UniProt AC	Q8BMS1
Protein Name	Trifunctional enzyme subunit alpha, mitochondrial
Gene Name	Hadha
Organism	Mus musculus (Mouse).
Sequence Length	763
Subcellular Localization	Mitochondrion matrix.
Protein Description	Bifunctional subunit..
Protein Sequence	MVASRAIGSLSRFSAFRILRSRGCICRSFTTSSALLTRTHINYGVKGDVAVIRINSPNSKVNTLNKEVQSEFIEVMNEIWANDQIRSAVLISSKPGCFVAGADINMLSSCTTPQEATRISQEGQRMFEKLEKSPKPVVAAISGSCLGGGLELAIACQYRIATKDRKTVLGVPEVLLGILPGAGGTQRLPKMVGVPAAFDMMLTGRNIRADRAKKMGLVDQLVEPLGPGIKSPEERTIEYLEEVAVNFAKGLADRKVSAKQSKGLVEKLTTYAMTVPFVRQQVYKTVEEKVKKQTKGLYPAPLKIIDAVKAGLEQGSDAGYLAESQKFGELALTKESKALMGLYNGQVLCKKNKFGAPQKNVQQLAILGAGLMGAGIAQVSVDKGLKTLLKDTTVTGLGRGQQQVFKGLNDKVKKKALTSFERDSIFSNLIGQLDYKGFEKADMVIEAVFEDLGVKHKVLKEVESVTPEHCIFASNTSALPINQIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTDKTSKDTTASAVAVGLRQGKVIIVVKDGPGFYTTRCLAPMMSEVMRILQEGVDPKKLDALTTGFGFPVGAATLADEVGVDVAQHVAEDLGKAFGERFGGGSVELLKQMVSKGFLGRKSGKGFYIYQEGSKNKSLNSEMDNILANLRLPAKPEVSSDEDVQYRVITRFVNEAVLCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKVVDRLRKYESAYGTQFTPCQLLLDHANNSSKKFYQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
46	Acetylation	THINYGVKGDVAVIR CEECCCCCCCEEEEE	45.06	23576753
46	Succinylation	THINYGVKGDVAVIR CEECCCCCCCEEEEE	45.06	-
46	Succinylation	THINYGVKGDVAVIR CEECCCCCCCEEEEE	45.06	23806337
46	Ubiquitination	THINYGVKGDVAVIR CEECCCCCCCEEEEE	45.06	-
60	Acetylation	RINSPNSKVNTLNKE EECCCCHHHCCCCHH	46.26	23806337
60	Glutarylation	RINSPNSKVNTLNKE EECCCCHHHCCCCHH	46.26	24703693
60	Malonylation	RINSPNSKVNTLNKE EECCCCHHHCCCCHH	46.26	26073543
60	Succinylation	RINSPNSKVNTLNKE EECCCCHHHCCCCHH	46.26	-
60	Succinylation	RINSPNSKVNTLNKE EECCCCHHHCCCCHH	46.26	23806337
60	Ubiquitination	RINSPNSKVNTLNKE EECCCCHHHCCCCHH	46.26	27667366
66	Acetylation	SKVNTLNKEVQSEFI HHHCCCCHHHHHHHH	63.48	22733758
120	Phosphorylation	PQEATRISQEGQRMF HHHHHHHCHHHHHHH	20.91	30482847
129	Acetylation	EGQRMFEKLEKSPKP HHHHHHHHHHCCCCC	51.16	23576753
129	Succinylation	EGQRMFEKLEKSPKP HHHHHHHHHHCCCCC	51.16	23806337
163	Acetylation	CQYRIATKDRKTVLG HCEEECCCCCCCCCC	46.65	23864654
163	Succinylation	CQYRIATKDRKTVLG HCEEECCCCCCCCCC	46.65	26388266
166	Acetylation	RIATKDRKTVLGVPE EECCCCCCCCCCCCH	53.79	23576753
166	Glutarylation	RIATKDRKTVLGVPE EECCCCCCCCCCCCH	53.79	24703693
166	Malonylation	RIATKDRKTVLGVPE EECCCCCCCCCCCCH	53.79	26320211
166	Succinylation	RIATKDRKTVLGVPE EECCCCCCCCCCCCH	53.79	-
166	Succinylation	RIATKDRKTVLGVPE EECCCCCCCCCCCCH	53.79	23806337
166	Ubiquitination	RIATKDRKTVLGVPE EECCCCCCCCCCCCH	53.79	-
167	Phosphorylation	IATKDRKTVLGVPEV ECCCCCCCCCCCCHH	23.12	23984901
185	Phosphorylation	ILPGAGGTQRLPKMV CCCCCCCCCCCCHHH	15.03	29233185
190	Ubiquitination	GGTQRLPKMVGVPAA CCCCCCCHHHCCCHH	51.30	22790023
203	Phosphorylation	AAFDMMLTGRNIRAD HHHHHHHHCCCCCHH	19.05	29119230
213	Acetylation	NIRADRAKKMGLVDQ CCCHHHHHHCCHHHH	44.16	23806337
213	Succinylation	NIRADRAKKMGLVDQ CCCHHHHHHCCHHHH	44.16	-
213	Succinylation	NIRADRAKKMGLVDQ CCCHHHHHHCCHHHH	44.16	23806337
214	Acetylation	IRADRAKKMGLVDQL CCHHHHHHCCHHHHH	36.90	23576753
214	Glutarylation	IRADRAKKMGLVDQL CCHHHHHHCCHHHHH	36.90	24703693
214	Malonylation	IRADRAKKMGLVDQL CCHHHHHHCCHHHHH	36.90	26320211
214	Phosphoglycerylation	IRADRAKKMGLVDQL CCHHHHHHCCHHHHH	36.90	-
214	Succinylation	IRADRAKKMGLVDQL CCHHHHHHCCHHHHH	36.90	-
214	Succinylation	IRADRAKKMGLVDQL CCHHHHHHCCHHHHH	36.90	23806337
214	Ubiquitination	IRADRAKKMGLVDQL CCHHHHHHCCHHHHH	36.90	-
230	Acetylation	EPLGPGIKSPEERTI CCCCCCCCCHHHHHH	66.91	23806337
230	Succinylation	EPLGPGIKSPEERTI CCCCCCCCCHHHHHH	66.91	-
230	Succinylation	EPLGPGIKSPEERTI CCCCCCCCCHHHHHH	66.91	23806337
231	Phosphorylation	PLGPGIKSPEERTIE CCCCCCCCHHHHHHH	35.31	26824392
249	Acetylation	EVAVNFAKGLADRKV HHHHHHHHHHHCCCC	50.77	23576753
249	Succinylation	EVAVNFAKGLADRKV HHHHHHHHHHHCCCC	50.77	-
249	Succinylation	EVAVNFAKGLADRKV HHHHHHHHHHHCCCC	50.77	23806337
255	Acetylation	AKGLADRKVSAKQSK HHHHHCCCCCHHHCC	40.88	6269753
255	Succinylation	AKGLADRKVSAKQSK HHHHHCCCCCHHHCC	40.88	26388266
259	Acetylation	ADRKVSAKQSKGLVE HCCCCCHHHCCCHHH	47.82	2393849
259	Succinylation	ADRKVSAKQSKGLVE HCCCCCHHHCCCHHH	47.82	26388266
262	Acetylation	KVSAKQSKGLVEKLT CCCHHHCCCHHHHHH	54.49	2393857
262	Succinylation	KVSAKQSKGLVEKLT CCCHHHCCCHHHHHH	54.49	26388266
267	Acetylation	QSKGLVEKLTTYAMT HCCCHHHHHHHHHHH	43.59	23576753
283	Phosphorylation	PFVRQQVYKTVEEKV HHHHHHHHHHHHHHH	9.15	20495213
284	Acetylation	FVRQQVYKTVEEKVK HHHHHHHHHHHHHHH	47.43	23954790
284	Succinylation	FVRQQVYKTVEEKVK HHHHHHHHHHHHHHH	47.43	26388266
289	Acetylation	VYKTVEEKVKKQTKG HHHHHHHHHHHHCCC	45.94	23576753
289	Succinylation	VYKTVEEKVKKQTKG HHHHHHHHHHHHCCC	45.94	26388266
291	Acetylation	KTVEEKVKKQTKGLY HHHHHHHHHHCCCCC	50.67	23576753
291	Succinylation	KTVEEKVKKQTKGLY HHHHHHHHHHCCCCC	50.67	26388266
292	Acetylation	TVEEKVKKQTKGLYP HHHHHHHHHCCCCCC	67.21	2393881
292	Glutarylation	TVEEKVKKQTKGLYP HHHHHHHHHCCCCCC	67.21	24703693
292	Succinylation	TVEEKVKKQTKGLYP HHHHHHHHHCCCCCC	67.21	26388266
295	Acetylation	EKVKKQTKGLYPAPL HHHHHHCCCCCCCCH	44.41	23864654
295	Glutarylation	EKVKKQTKGLYPAPL HHHHHHCCCCCCCCH	44.41	24703693
295	Malonylation	EKVKKQTKGLYPAPL HHHHHHCCCCCCCCH	44.41	26320211
295	Succinylation	EKVKKQTKGLYPAPL HHHHHHCCCCCCCCH	44.41	-
295	Ubiquitination	EKVKKQTKGLYPAPL HHHHHHCCCCCCCCH	44.41	-
303	Acetylation	GLYPAPLKIIDAVKA CCCCCCHHHHHHHHH	36.23	23576753
303	Glutarylation	GLYPAPLKIIDAVKA CCCCCCHHHHHHHHH	36.23	24703693
303	Succinylation	GLYPAPLKIIDAVKA CCCCCCHHHHHHHHH	36.23	-
303	Succinylation	GLYPAPLKIIDAVKA CCCCCCHHHHHHHHH	36.23	23806337
303	Ubiquitination	GLYPAPLKIIDAVKA CCCCCCHHHHHHHHH	36.23	-
309	Acetylation	LKIIDAVKAGLEQGS HHHHHHHHHHHHCCC	38.16	23576753
309	Succinylation	LKIIDAVKAGLEQGS HHHHHHHHHHHHCCC	38.16	26388266
309	Ubiquitination	LKIIDAVKAGLEQGS HHHHHHHHHHHHCCC	38.16	-
316	Phosphorylation	KAGLEQGSDAGYLAE HHHHHCCCCCHHHHH	24.79	25521595
320	Phosphorylation	EQGSDAGYLAESQKF HCCCCCHHHHHHHCC	12.40	27742792
326	Acetylation	GYLAESQKFGELALT HHHHHHHCCCCEECC	65.69	23576753
326	Succinylation	GYLAESQKFGELALT HHHHHHHCCCCEECC	65.69	-
326	Succinylation	GYLAESQKFGELALT HHHHHHHCCCCEECC	65.69	23806337
326	Ubiquitination	GYLAESQKFGELALT HHHHHHHCCCCEECC	65.69	-
333	Phosphorylation	KFGELALTKESKALM CCCCEECCHHHHHHH	27.45	21183079
334	Acetylation	FGELALTKESKALMG CCCEECCHHHHHHHH	61.92	23576753
334	Glutarylation	FGELALTKESKALMG CCCEECCHHHHHHHH	61.92	24703693
334	Succinylation	FGELALTKESKALMG CCCEECCHHHHHHHH	61.92	-
334	Succinylation	FGELALTKESKALMG CCCEECCHHHHHHHH	61.92	23806337
337	Acetylation	LALTKESKALMGLYN EECCHHHHHHHHHHC	46.78	23864654
349	S-nitrosocysteine	LYNGQVLCKKNKFGA HHCCEEEECCCCCCC	6.57	-
349	S-nitrosylation	LYNGQVLCKKNKFGA HHCCEEEECCCCCCC	6.57	21278135
349	S-palmitoylation	LYNGQVLCKKNKFGA HHCCEEEECCCCCCC	6.57	28526873
350	Acetylation	YNGQVLCKKNKFGAP HCCEEEECCCCCCCC	56.04	23576753
350	Glutarylation	YNGQVLCKKNKFGAP HCCEEEECCCCCCCC	56.04	24703693
350	Malonylation	YNGQVLCKKNKFGAP HCCEEEECCCCCCCC	56.04	26320211
350	Succinylation	YNGQVLCKKNKFGAP HCCEEEECCCCCCCC	56.04	-
350	Succinylation	YNGQVLCKKNKFGAP HCCEEEECCCCCCCC	56.04	23806337
350	Ubiquitination	YNGQVLCKKNKFGAP HCCEEEECCCCCCCC	56.04	-
351	Acetylation	NGQVLCKKNKFGAPQ CCEEEECCCCCCCCC	65.46	23201123
351	Succinylation	NGQVLCKKNKFGAPQ CCEEEECCCCCCCCC	65.46	26388266
353	Acetylation	QVLCKKNKFGAPQKN EEEECCCCCCCCCCC	54.80	23576753
353	Succinylation	QVLCKKNKFGAPQKN EEEECCCCCCCCCCC	54.80	23806337
383	Succinylation	IAQVSVDKGLKTLLK EEEEECCCHHHHHHH	65.08	26388266
386	Acetylation	VSVDKGLKTLLKDTT EECCCHHHHHHHCCC	45.88	23864654
390	Acetylation	KGLKTLLKDTTVTGL CHHHHHHHCCCCCCC	57.02	23864654
390	Succinylation	KGLKTLLKDTTVTGL CHHHHHHHCCCCCCC	57.02	23806337
390	Ubiquitination	KGLKTLLKDTTVTGL CHHHHHHHCCCCCCC	57.02	-
393	Phosphorylation	KTLLKDTTVTGLGRG HHHHHCCCCCCCCHH	26.63	23737553
395	Phosphorylation	LLKDTTVTGLGRGQQ HHHCCCCCCCCHHHH	25.29	23737553
399	Methylation	TTVTGLGRGQQQVFK CCCCCCCHHHHHHHH	44.80	24129315
406	Acetylation	RGQQQVFKGLNDKVK HHHHHHHHCCCHHHH	64.73	23806337
406	Glutarylation	RGQQQVFKGLNDKVK HHHHHHHHCCCHHHH	64.73	24703693
406	Malonylation	RGQQQVFKGLNDKVK HHHHHHHHCCCHHHH	64.73	26073543
406	Succinylation	RGQQQVFKGLNDKVK HHHHHHHHCCCHHHH	64.73	-
406	Succinylation	RGQQQVFKGLNDKVK HHHHHHHHCCCHHHH	64.73	23806337
406	Ubiquitination	RGQQQVFKGLNDKVK HHHHHHHHCCCHHHH	64.73	-
411	Acetylation	VFKGLNDKVKKKALT HHHCCCHHHHHHHCH	55.68	23576753
411	Malonylation	VFKGLNDKVKKKALT HHHCCCHHHHHHHCH	55.68	26320211
411	Succinylation	VFKGLNDKVKKKALT HHHCCCHHHHHHHCH	55.68	-
411	Succinylation	VFKGLNDKVKKKALT HHHCCCHHHHHHHCH	55.68	23806337
413	Acetylation	KGLNDKVKKKALTSF HCCCHHHHHHHCHHH	55.06	23864654
413	Malonylation	KGLNDKVKKKALTSF HCCCHHHHHHHCHHH	55.06	26073543
413	Succinylation	KGLNDKVKKKALTSF HCCCHHHHHHHCHHH	55.06	24315375
414	Acetylation	GLNDKVKKKALTSFE CCCHHHHHHHCHHHH	46.39	24062335
414	Succinylation	GLNDKVKKKALTSFE CCCHHHHHHHCHHHH	46.39	23806337
415	Acetylation	LNDKVKKKALTSFER CCHHHHHHHCHHHHH	42.80	23806337
415	Glutarylation	LNDKVKKKALTSFER CCHHHHHHHCHHHHH	42.80	24703693
415	Malonylation	LNDKVKKKALTSFER CCHHHHHHHCHHHHH	42.80	26320211
415	Succinylation	LNDKVKKKALTSFER CCHHHHHHHCHHHHH	42.80	-
415	Succinylation	LNDKVKKKALTSFER CCHHHHHHHCHHHHH	42.80	23806337
415	Ubiquitination	LNDKVKKKALTSFER CCHHHHHHHCHHHHH	42.80	-
418	Phosphorylation	KVKKKALTSFERDSI HHHHHHCHHHHHHHH	35.91	27742792
419	Phosphorylation	VKKKALTSFERDSIF HHHHHCHHHHHHHHH	26.43	23737553
424	Phosphorylation	LTSFERDSIFSNLIG CHHHHHHHHHHHHHH	31.58	23984901
427	Phosphorylation	FERDSIFSNLIGQLD HHHHHHHHHHHHHCC	29.11	23984901
436	Acetylation	LIGQLDYKGFEKADM HHHHCCCCCHHHHHH	57.71	23576753
436	Succinylation	LIGQLDYKGFEKADM HHHHCCCCCHHHHHH	57.71	-
436	Succinylation	LIGQLDYKGFEKADM HHHHCCCCCHHHHHH	57.71	23806337
440	Acetylation	LDYKGFEKADMVIEA CCCCCHHHHHHHHHH	47.64	23806337
440	Succinylation	LDYKGFEKADMVIEA CCCCCHHHHHHHHHH	47.64	-
440	Succinylation	LDYKGFEKADMVIEA CCCCCHHHHHHHHHH	47.64	23806337
455	Ubiquitination	VFEDLGVKHKVLKEV HHHHHCCCHHHHHHC	35.59	22790023
457	Acetylation	EDLGVKHKVLKEVES HHHCCCHHHHHHCCC	43.47	24062335
460	Acetylation	GVKHKVLKEVESVTP CCCHHHHHHCCCCCH	63.80	23576753
460	Succinylation	GVKHKVLKEVESVTP CCCHHHHHHCCCCCH	63.80	-
460	Succinylation	GVKHKVLKEVESVTP CCCHHHHHHCCCCCH	63.80	23806337
470	S-nitrosocysteine	ESVTPEHCIFASNTS CCCCHHHEEECCCCC	2.33	-
470	S-nitrosylation	ESVTPEHCIFASNTS CCCCHHHEEECCCCC	2.33	21278135
470	S-palmitoylation	ESVTPEHCIFASNTS CCCCHHHEEECCCCC	2.33	28526873
489	Succinylation	NQIAAVSKRPEKVIG HHHHHHCCCCHHEEE	66.43	24315375
493	Acetylation	AVSKRPEKVIGMHYF HHCCCCHHEEEEEEC	41.66	24062335
505	Acetylation	HYFSPVDKMQLLEII EECCCCCHHHEEEEH	28.87	23576753
505	Malonylation	HYFSPVDKMQLLEII EECCCCCHHHEEEEH	28.87	26073543
505	Succinylation	HYFSPVDKMQLLEII EECCCCCHHHEEEEH	28.87	-
505	Succinylation	HYFSPVDKMQLLEII EECCCCCHHHEEEEH	28.87	23806337
516	Acetylation	LEIITTDKTSKDTTA EEEHHCCCCCCCCCH	53.24	23864654
516	Succinylation	LEIITTDKTSKDTTA EEEHHCCCCCCCCCH	53.24	23806337
519	Acetylation	ITTDKTSKDTTASAV HHCCCCCCCCCHHHH	65.41	23576753
519	Glutarylation	ITTDKTSKDTTASAV HHCCCCCCCCCHHHH	65.41	24703693
519	Malonylation	ITTDKTSKDTTASAV HHCCCCCCCCCHHHH	65.41	26073543
519	Succinylation	ITTDKTSKDTTASAV HHCCCCCCCCCHHHH	65.41	-
519	Succinylation	ITTDKTSKDTTASAV HHCCCCCCCCCHHHH	65.41	23806337
519	Ubiquitination	ITTDKTSKDTTASAV HHCCCCCCCCCHHHH	65.41	-
540	Acetylation	GKVIIVVKDGPGFYT CEEEEEEECCCCCCH	46.18	23576753
540	Succinylation	GKVIIVVKDGPGFYT CEEEEEEECCCCCCH	46.18	26388266
540	Ubiquitination	GKVIIVVKDGPGFYT CEEEEEEECCCCCCH	46.18	-
550	S-nitrosocysteine	PGFYTTRCLAPMMSE CCCCHHHHHHHHHHH	3.40	-
550	S-nitrosylation	PGFYTTRCLAPMMSE CCCCHHHHHHHHHHH	3.40	21278135
556	Phosphorylation	RCLAPMMSEVMRILQ HHHHHHHHHHHHHHH	22.31	27566939
569	Acetylation	LQEGVDPKKLDALTT HHCCCCHHHCHHHHC	62.60	23576753
569	Glutarylation	LQEGVDPKKLDALTT HHCCCCHHHCHHHHC	62.60	24703693
569	Malonylation	LQEGVDPKKLDALTT HHCCCCHHHCHHHHC	62.60	26073543
569	Succinylation	LQEGVDPKKLDALTT HHCCCCHHHCHHHHC	62.60	-
569	Succinylation	LQEGVDPKKLDALTT HHCCCCHHHCHHHHC	62.60	23806337
569	Ubiquitination	LQEGVDPKKLDALTT HHCCCCHHHCHHHHC	62.60	-
570	Acetylation	QEGVDPKKLDALTTG HCCCCHHHCHHHHCC	57.92	24062335
570	Succinylation	QEGVDPKKLDALTTG HCCCCHHHCHHHHCC	57.92	24315375
575	Phosphorylation	PKKLDALTTGFGFPV HHHCHHHHCCCCCCC	26.96	20495213
576	Phosphorylation	KKLDALTTGFGFPVG HHCHHHHCCCCCCCC	31.22	20495213
586	Phosphorylation	GFPVGAATLADEVGV CCCCCHHHHHHHHCC	23.19	20495213
615	Phosphorylation	GERFGGGSVELLKQM HHHHCCCHHHHHHHH	18.72	19060867
620	Acetylation	GGSVELLKQMVSKGF CCHHHHHHHHHHCCC	49.31	23806337
620	Succinylation	GGSVELLKQMVSKGF CCHHHHHHHHHHCCC	49.31	-
620	Succinylation	GGSVELLKQMVSKGF CCHHHHHHHHHHCCC	49.31	23806337
620	Ubiquitination	GGSVELLKQMVSKGF CCHHHHHHHHHHCCC	49.31	-
625	Acetylation	LLKQMVSKGFLGRKS HHHHHHHCCCCCCCC	42.12	24062335
631	Acetylation	SKGFLGRKSGKGFYI HCCCCCCCCCCCEEE	62.86	2393941
632	Phosphorylation	KGFLGRKSGKGFYIY CCCCCCCCCCCEEEE	44.36	26643407
634	Acetylation	FLGRKSGKGFYIYQE CCCCCCCCCEEEEEC	53.60	23806337
634	Succinylation	FLGRKSGKGFYIYQE CCCCCCCCCEEEEEC	53.60	-
634	Succinylation	FLGRKSGKGFYIYQE CCCCCCCCCEEEEEC	53.60	23806337
637	Phosphorylation	RKSGKGFYIYQEGSK CCCCCCEEEEECCCC	13.85	26643407
639	Phosphorylation	SGKGFYIYQEGSKNK CCCCEEEEECCCCCC	6.80	26643407
643	Phosphorylation	FYIYQEGSKNKSLNS EEEEECCCCCCCCCH	32.10	23737553
644	Acetylation	YIYQEGSKNKSLNSE EEEECCCCCCCCCHH	78.30	23576753
644	Glutarylation	YIYQEGSKNKSLNSE EEEECCCCCCCCCHH	78.30	24703693
644	Malonylation	YIYQEGSKNKSLNSE EEEECCCCCCCCCHH	78.30	26073543
644	Succinylation	YIYQEGSKNKSLNSE EEEECCCCCCCCCHH	78.30	-
644	Succinylation	YIYQEGSKNKSLNSE EEEECCCCCCCCCHH	78.30	23806337
644	Ubiquitination	YIYQEGSKNKSLNSE EEEECCCCCCCCCHH	78.30	-
646	Acetylation	YQEGSKNKSLNSEMD EECCCCCCCCCHHHH	61.12	23806337
646	Succinylation	YQEGSKNKSLNSEMD EECCCCCCCCCHHHH	61.12	-
646	Succinylation	YQEGSKNKSLNSEMD EECCCCCCCCCHHHH	61.12	23806337
646	Ubiquitination	YQEGSKNKSLNSEMD EECCCCCCCCCHHHH	61.12	-
647	Phosphorylation	QEGSKNKSLNSEMDN ECCCCCCCCCHHHHH	42.02	23737553
650	Phosphorylation	SKNKSLNSEMDNILA CCCCCCCHHHHHHHH	39.32	23737553
664	Acetylation	ANLRLPAKPEVSSDE HHCCCCCCCCCCCCC	39.51	23576753
664	Glutarylation	ANLRLPAKPEVSSDE HHCCCCCCCCCCCCC	39.51	24703693
664	Succinylation	ANLRLPAKPEVSSDE HHCCCCCCCCCCCCC	39.51	-
664	Succinylation	ANLRLPAKPEVSSDE HHCCCCCCCCCCCCC	39.51	23806337
664	Ubiquitination	ANLRLPAKPEVSSDE HHCCCCCCCCCCCCC	39.51	-
668	Phosphorylation	LPAKPEVSSDEDVQY CCCCCCCCCCCCHHH	30.34	26525534
669	Phosphorylation	PAKPEVSSDEDVQYR CCCCCCCCCCCHHHH	50.63	26525534
675	Phosphorylation	SSDEDVQYRVITRFV CCCCCHHHHHHHHHH	13.49	26032504
724	Phosphorylation	PFRFVDLYGAQKVVD CEEEEHHHCHHHHHH	13.12	17242355
728	Acetylation	VDLYGAQKVVDRLRK EHHHCHHHHHHHHHH	43.63	23576753
728	Glutarylation	VDLYGAQKVVDRLRK EHHHCHHHHHHHHHH	43.63	24703693
728	Malonylation	VDLYGAQKVVDRLRK EHHHCHHHHHHHHHH	43.63	26320211
728	Succinylation	VDLYGAQKVVDRLRK EHHHCHHHHHHHHHH	43.63	-
728	Succinylation	VDLYGAQKVVDRLRK EHHHCHHHHHHHHHH	43.63	23806337
728	Ubiquitination	VDLYGAQKVVDRLRK EHHHCHHHHHHHHHH	43.63	-
735	Acetylation	KVVDRLRKYESAYGT HHHHHHHHHHHHHCC	58.94	23576753
735	Ubiquitination	KVVDRLRKYESAYGT HHHHHHHHHHHHHCC	58.94	22790023
745	Phosphorylation	SAYGTQFTPCQLLLD HHHCCCCCHHHHHHH	17.21	27742792
747	S-nitrosocysteine	YGTQFTPCQLLLDHA HCCCCCHHHHHHHCC	3.96	-
747	S-nitrosylation	YGTQFTPCQLLLDHA HCCCCCHHHHHHHCC	3.96	21278135
747	S-palmitoylation	YGTQFTPCQLLLDHA HCCCCCHHHHHHHCC	3.96	28526873
757	Phosphorylation	LLDHANNSSKKFYQ- HHHCCCCCCCCCCC-	43.26	27742792
758	Phosphorylation	LDHANNSSKKFYQ-- HHCCCCCCCCCCC--	41.82	27742792
759	Acetylation	DHANNSSKKFYQ--- HCCCCCCCCCCC---	46.88	23576753
759	Succinylation	DHANNSSKKFYQ--- HCCCCCCCCCCC---	46.88	-
759	Succinylation	DHANNSSKKFYQ--- HCCCCCCCCCCC---	46.88	23806337
759	Ubiquitination	DHANNSSKKFYQ--- HCCCCCCCCCCC---	46.88	-
760	Acetylation	HANNSSKKFYQ---- CCCCCCCCCCC----	51.78	155825
760	Succinylation	HANNSSKKFYQ---- CCCCCCCCCCC----	51.78	26388266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ECHA_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Reference
569	K	Acetylation	23806337
Acetylation of Lys-569 and Lys-728 is observed in liver mitochondria from fasted mice but not from fed mice.
728	K	Acetylation	23806337
Acetylation of Lys-569 and Lys-728 is observed in liver mitochondria from fasted mice but not from fed mice.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ECHA_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ECHA_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ECHA_MOUSE

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Substrate and functional diversity of lysine acetylation revealed bya proteomics survey."; Kim S.C., Sprung R., Chen Y., Xu Y., Ball H., Pei J., Cheng T.,Kho Y., Xiao H., Xiao L., Grishin N.V., White M., Yang X.-J., Zhao Y.; Mol. Cell 23:607-618(2006). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-129; LYS-326; LYS-350;LYS-569 AND LYS-728, AND MASS SPECTROMETRY.	16916647 [Abstract]

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