IGLL5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IGLL5_HUMAN
• UniProt AC: B9A064
• Protein Name: Immunoglobulin lambda-like polypeptide 5
• Gene Name: IGLL5
• Organism: Homo sapiens (Human).
• Sequence Length: 214
• Subcellular Localization: Secreted.
• Protein Sequence: MRPKTGQVGCETPEELGPGPRQRWPLLLLGLAMVAHGLLRPMVAPQSGDPDPGASVGSSRSSLRSLWGRLLLQPSPQRADPRCWPRGFWSEPQSLCYVFGTGTKVTVLGQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	TGQVGCETPEELGPG CCCCCCCCHHHHCCC	39.82	30206219
59	Phosphorylation	PGASVGSSRSSLRSL CCCCCCCCHHHHHHH	30.19	28787133
61	Phosphorylation	ASVGSSRSSLRSLWG CCCCCCHHHHHHHHH	35.35	28787133
62	Phosphorylation	SVGSSRSSLRSLWGR CCCCCHHHHHHHHHH	27.05	28787133
65	Phosphorylation	SSRSSLRSLWGRLLL CCHHHHHHHHHHHHC	33.49	28787133
90	Phosphorylation	CWPRGFWSEPQSLCY CCCCCCCCCCCEEEE	36.82	28270605
94	Phosphorylation	GFWSEPQSLCYVFGT CCCCCCCEEEEEECC	30.99	28270605
97	Phosphorylation	SEPQSLCYVFGTGTK CCCCEEEEEECCCCE	12.24	28270605
101	Phosphorylation	SLCYVFGTGTKVTVL EEEEEECCCCEEEEC	30.16	28270605
103	Phosphorylation	CYVFGTGTKVTVLGQ EEEECCCCEEEECCC	23.37	28270605
106	Phosphorylation	FGTGTKVTVLGQPKA ECCCCEEEECCCCCC	16.15	28270605
147	Phosphorylation	DFYPGAVTVAWKADG CCCCCCEEEEEECCC	12.17	-
173	Ubiquitination	PSKQSNNKYAASSYL CCCCCCCCEECHHHC	40.28	2190698
177	Phosphorylation	SNNKYAASSYLSLTP CCCCEECHHHCCCCH	16.02	25159151
178	Phosphorylation	NNKYAASSYLSLTPE CCCEECHHHCCCCHH	25.93	20068231
179	Phosphorylation	NKYAASSYLSLTPEQ CCEECHHHCCCCHHH	9.60	-
181	Phosphorylation	YAASSYLSLTPEQWK EECHHHCCCCHHHHH	23.20	25159151
188	Acetylation	SLTPEQWKSHRSYSC CCCHHHHHHCCCEEE	35.76	-
192	Phosphorylation	EQWKSHRSYSCQVTH HHHHHCCCEEEEEEE	18.90	28270605
193	Phosphorylation	QWKSHRSYSCQVTHE HHHHCCCEEEEEEEC	17.27	23312004
194	Phosphorylation	WKSHRSYSCQVTHEG HHHCCCEEEEEEECC	10.18	23911959

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IGLL5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IGLL5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IGLL5_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IGLL1_HUMAN	IGLL1	physical	26186194
IGLL1_HUMAN	IGLL1	physical	28514442
TRI68_HUMAN	TRIM68	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.