IGLL1_HUMAN - dbPTM
IGLL1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IGLL1_HUMAN
UniProt AC P15814
Protein Name Immunoglobulin lambda-like polypeptide 1
Gene Name IGLL1
Organism Homo sapiens (Human).
Sequence Length 213
Subcellular Localization Secreted .
Protein Description Critical for B-cell development..
Protein Sequence MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSRSSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
58PhosphorylationGPGAPGGSSRSSLRS
CCCCCCCCCHHHHHH		28.6123401153
59PhosphorylationPGAPGGSSRSSLRSR
CCCCCCCCHHHHHHH		39.1823401153
62PhosphorylationPGGSSRSSLRSRWGR
CCCCCHHHHHHHHHH		27.0524850871
76PhosphorylationRFLLQRGSWTGPRCW
HHHHHCCCCCCCCCC		24.5323401153
93PhosphorylationGFQSKHNSVTHVFGS
CCCCCCCCCEEEECC		28.2823401153
95O-linked_GlycosylationQSKHNSVTHVFGSGT
CCCCCCCEEEECCCC		16.49OGP
102O-linked_GlycosylationTHVFGSGTQLTVLSQ
EEEECCCCEEEEEEC		23.31OGP
105O-linked_GlycosylationFGSGTQLTVLSQPKA
ECCCCEEEEEECCCC		15.02OGP
113O-linked_GlycosylationVLSQPKATPSVTLFP
EEECCCCCCCEEEEC		23.40OGP
117O-linked_GlycosylationPKATPSVTLFPPSSE
CCCCCCEEEECCCHH		27.33OGP
154PhosphorylationVTWKADGTPITQGVE
EEEECCCCCCCCEEE		16.4422210691
172UbiquitinationPSKQSNNKYAASSYL
CCCCCCCCEECHHHC		40.2821906983
173PhosphorylationSKQSNNKYAASSYLS
CCCCCCCEECHHHCC		14.9923836654
176PhosphorylationSNNKYAASSYLSLTP
CCCCEECHHHCCCCH		16.0220068231
177PhosphorylationNNKYAASSYLSLTPE
CCCEECHHHCCCCHH		25.9320068231
178PhosphorylationNKYAASSYLSLTPEQ
CCEECHHHCCCCHHH		9.6020068231
180PhosphorylationYAASSYLSLTPEQWR
EECHHHCCCCHHHHH		23.2020068231
182PhosphorylationASSYLSLTPEQWRSR
CHHHCCCCHHHHHHC		22.7720068231
188PhosphorylationLTPEQWRSRRSYSCQ
CCHHHHHHCCCEEEE		29.14-
191PhosphorylationEQWRSRRSYSCQVMH
HHHHHCCCEEEEEEE		21.93-
192PhosphorylationQWRSRRSYSCQVMHE
HHHHCCCEEEEEEEC		16.20-
193O-linked_GlycosylationWRSRRSYSCQVMHEG
HHHCCCEEEEEEECC		10.18OGP
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IGLL1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IGLL1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IGLL1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of IGLL1_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
613500Agammaglobulinemia 2, autosomal recessive (AGM2)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IGLL1_HUMAN

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Related Literatures of Post-Translational Modification

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