| UniProt ID | TRIMM_HUMAN | |
|---|---|---|
| UniProt AC | Q8N7C3 | |
| Protein Name | Probable E3 ubiquitin-protein ligase TRIML2 | |
| Gene Name | TRIML2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 387 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MVCGIQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSLCIPNGDTSPDSLTILQHGPSCDATVSP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 6 (in isoform 2) | Phosphorylation | - | 21.40 | 30266825 | |
| 14 (in isoform 2) | Phosphorylation | - | 43.20 | 30266825 | |
| 18 (in isoform 2) | Phosphorylation | - | 41.95 | 23927012 | |
| 81 | Ubiquitination | LQRQQECISDLNLRE HHHHHHHHHHHHHHH | 3.36 | - | |
| 136 | Phosphorylation | RASEQVRSLLKLIVE HHHHHHHHHHHHHHH | 38.92 | 24719451 | |
| 162 | O-linked_Glycosylation | LLKNAKYSLERSKSL HHHHHCHHHHHCHHH | 24.05 | 30379171 | |
| 280 | Phosphorylation | GSADAKGSTARASGE CCCCCCCCCCCCCCC | 20.42 | 24850871 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TRIMM_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TRIMM_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TRIMM_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MTM1_HUMAN | MTM1 | physical | 28514442 | |
| CCD92_HUMAN | CCDC92 | physical | 28514442 | |
| BORC5_HUMAN | LOH12CR1 | physical | 28514442 | |
| KAISO_HUMAN | ZBTB33 | physical | 28514442 | |
| MINT_HUMAN | SPEN | physical | 28514442 | |
| SRGP2_HUMAN | SRGAP2 | physical | 28514442 | |
| KXDL1_HUMAN | KXD1 | physical | 28514442 | |
| BL1S2_HUMAN | BLOC1S2 | physical | 28514442 | |
| PML_HUMAN | PML | physical | 28514442 | |
| STIP1_HUMAN | STIP1 | physical | 28514442 | |
| SIKE1_HUMAN | SIKE1 | physical | 28514442 | |
| DTBP1_HUMAN | DTNBP1 | physical | 28514442 | |
| SNAPN_HUMAN | SNAPIN | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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