DSRAD_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DSRAD_HUMAN
• UniProt AC: P55265
• Protein Name: Double-stranded RNA-specific adenosine deaminase
• Gene Name: ADAR
• Organism: Homo sapiens (Human).
• Sequence Length: 1226
• Subcellular Localization: Isoform 1: Cytoplasm . Nucleus . Shuttles between the cytoplasm and nucleus (PubMed:7565688, PubMed:24753571). Nuclear import is mediated by TNPO1 (PubMed:24753571).; Isoform 5: Cytoplasm . Nucleus . Nucleus, nucleolus . Predominantly nuclear bu
• Protein Description: Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. [PubMed: 7972084]
• Protein Sequence: MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQTPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLRSQGLQRGFQHPSPRGRSLPQRGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSEDLLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Methylation	----MNPRQGYSLSG ----CCCCCCCCCCC	54.90	-
7	Phosphorylation	-MNPRQGYSLSGYYT -CCCCCCCCCCCEEC	9.71	26552605
8	Phosphorylation	MNPRQGYSLSGYYTH CCCCCCCCCCCEECC	23.92	26552605
10	Phosphorylation	PRQGYSLSGYYTHPF CCCCCCCCCEECCCC	20.86	26552605
12	Phosphorylation	QGYSLSGYYTHPFQG CCCCCCCEECCCCCC	11.21	26552605
13	Phosphorylation	GYSLSGYYTHPFQGY CCCCCCEECCCCCCC	11.33	25332170
14	Phosphorylation	YSLSGYYTHPFQGYE CCCCCEECCCCCCCE	18.00	30814671
20	Phosphorylation	YTHPFQGYEHRQLRY ECCCCCCCEEEEECC	9.59	26552605
25	Ubiquitination	QGYEHRQLRYQQPGP CCCEEEEECCCCCCC	5.77	29967540
26	Asymmetric dimethylarginine	GYEHRQLRYQQPGPG CCEEEEECCCCCCCC	20.90	-
26	Methylation	GYEHRQLRYQQPGPG CCEEEEECCCCCCCC	20.90	24129315
31	Neddylation	QLRYQQPGPGSSPSS EECCCCCCCCCCHHH	34.56	32015554
31	Ubiquitination	QLRYQQPGPGSSPSS EECCCCCCCCCCHHH	34.56	32015554
34	Phosphorylation	YQQPGPGSSPSSFLL CCCCCCCCCHHHHHH	42.06	26714015
35	Phosphorylation	QQPGPGSSPSSFLLK CCCCCCCCHHHHHHH	34.41	27251275
37	Phosphorylation	PGPGSSPSSFLLKQI CCCCCCHHHHHHHHH	35.35	27251275
38	Phosphorylation	GPGSSPSSFLLKQIE CCCCCHHHHHHHHHH	24.25	27251275
48	Methylation	LKQIEFLKGQLPEAP HHHHHHHCCCCCCCC	50.35	-
48	Ubiquitination	LKQIEFLKGQLPEAP HHHHHHHCCCCCCCC	50.35	22505724
54	Ubiquitination	LKGQLPEAPVIGKQT HCCCCCCCCCCCCCC	11.17	22505724
58	Ubiquitination	LPEAPVIGKQTPSLP CCCCCCCCCCCCCCC	19.09	22505724
63	O-linked_Glycosylation	VIGKQTPSLPPSLPG CCCCCCCCCCCCCCC	57.82	30059200
63	Ubiquitination	VIGKQTPSLPPSLPG CCCCCCCCCCCCCCC	57.82	29967540
89	Ubiquitination	STRGRQVDIRGVPRG CCCCCEEECCCCCCC	19.27	32015554
91	Methylation	RGRQVDIRGVPRGVH CCCEEECCCCCCCCC	35.28	-
91	Ubiquitination	RGRQVDIRGVPRGVH CCCEEECCCCCCCCC	35.28	22505724
91 (in isoform 4)	Ubiquitination	-	35.28	-
95	Methylation	VDIRGVPRGVHLRSQ EECCCCCCCCCHHHH	58.31	-
112	Phosphorylation	QRGFQHPSPRGRSLP HCCCCCCCCCCCCCC	25.71	17081983
114	Methylation	GFQHPSPRGRSLPQR CCCCCCCCCCCCCHH	58.45	-
123	Ubiquitination	RSLPQRGVDCLSSHF CCCCHHCCCHHHHHH	5.24	32015554
136	Phosphorylation	HFQELSIYQDQEQRI HHHHHCCCCCHHHHH	11.58	29138951
138	Ubiquitination	QELSIYQDQEQRILK HHHCCCCCHHHHHHH	36.69	32015554
145	Acetylation	DQEQRILKFLEELGE CHHHHHHHHHHHHCC	45.60	26051181
148	Ubiquitination	QRILKFLEELGEGKA HHHHHHHHHHCCCCC	55.07	21890473
148	Ubiquitination	QRILKFLEELGEGKA HHHHHHHHHHCCCCC	55.07	21890473
148 (in isoform 5)	Ubiquitination	-	55.07	21890473
154	Ubiquitination	LEELGEGKATTAHDL HHHHCCCCCCCHHHH	37.95	29967540
164	Ubiquitination	TAHDLSGKLGTPKKE CHHHHCCCCCCCHHH	40.13	29967540
167	Phosphorylation	DLSGKLGTPKKEINR HHCCCCCCCHHHHHH	42.23	23186163
177	Phosphorylation	KEINRVLYSLAKKGK HHHHHHHHHHHHHCC	9.97	21709919
181	Acetylation	RVLYSLAKKGKLQKE HHHHHHHHHCCCHHH	68.31	25953088
181	Ubiquitination	RVLYSLAKKGKLQKE HHHHHHHHHCCCHHH	68.31	29967540
187	Ubiquitination	AKKGKLQKEAGTPPL HHHCCCHHHCCCCCH	61.03	29967540
191	Phosphorylation	KLQKEAGTPPLWKIA CCHHHCCCCCHHHEE	28.87	45553641
196	Phosphorylation	AGTPPLWKIAVSTQA CCCCCHHHEEEECCH	28.59	32645325
200	Phosphorylation	PLWKIAVSTQAWNQH CHHHEEEECCHHHHC	13.04	26714015
200	Ubiquitination	PLWKIAVSTQAWNQH CHHHEEEECCHHHHC	13.04	29967540
201	Phosphorylation	LWKIAVSTQAWNQHS HHHEEEECCHHHHCC	18.73	26714015
208	Phosphorylation	TQAWNQHSGVVRPDG CCHHHHCCCEECCCC	24.42	26714015
217	Phosphorylation	VVRPDGHSQGAPNSD EECCCCCCCCCCCCC	35.52	26714015
263	Ubiquitination	HSGVVRPDSHSQGSP CCCCCCCCCCCCCCC	48.71	29967540
269	Ubiquitination	PDSHSQGSPNSDPGL CCCCCCCCCCCCCCC	17.17	29967540
272 (in isoform 1)	Phosphorylation	-	48.87	-
279	Ubiquitination	SDPGLEPEDSNSTSA CCCCCCCCCCCCCCC	65.77	29967540
285	Phosphorylation	PEDSNSTSALEDPLE CCCCCCCCCCCCHHH	30.58	-
285	Ubiquitination	PEDSNSTSALEDPLE CCCCCCCCCCCCHHH	30.58	29967540
296	Ubiquitination	DPLEFLDMAEIKEKI CHHHHHCHHHHHHHH	3.81	33845483
300	Ubiquitination	FLDMAEIKEKICDYL HHCHHHHHHHHHHHH	44.45	29967540
300 (in isoform 5)	Ubiquitination	-	44.45	21890473
302	Acetylation	DMAEIKEKICDYLFN CHHHHHHHHHHHHHC	43.57	26051181
302	Ubiquitination	DMAEIKEKICDYLFN CHHHHHHHHHHHHHC	43.57	29967540
304 (in isoform 1)	Phosphorylation	-	4.10	-
306 (in isoform 1)	Phosphorylation	-	14.58	-
306	Phosphorylation	IKEKICDYLFNVSDS HHHHHHHHHHCCCCH	14.58	33259812
308	Phosphorylation	EKICDYLFNVSDSSA HHHHHHHHCCCCHHH	7.45	32142685
313 (in isoform 1)	Phosphorylation	-	15.25	-
313	Phosphorylation	YLFNVSDSSALNLAK HHHCCCCHHHHHHHH	15.25	18669648
316 (in isoform 1)	Phosphorylation	-	6.11	-
318	Ubiquitination	SDSSALNLAKNIGLT CCHHHHHHHHHCCCC	8.15	29967540
319 (in isoform 1)	Phosphorylation	-	11.19	-
319	Phosphorylation	DSSALNLAKNIGLTK CHHHHHHHHHCCCCC	11.19	32142685
320	Ubiquitination	SSALNLAKNIGLTKA HHHHHHHHHCCCCCC	52.87	29967540
326	2-Hydroxyisobutyrylation	AKNIGLTKARDINAV HHHCCCCCCHHCCEE	46.60	-
326	Acetylation	AKNIGLTKARDINAV HHHCCCCCCHHCCEE	46.60	25953088
326	Neddylation	AKNIGLTKARDINAV HHHCCCCCCHHCCEE	46.60	32015554
326	Ubiquitination	AKNIGLTKARDINAV HHHCCCCCCHHCCEE	46.60	32015554
330	Ubiquitination	GLTKARDINAVLIDM CCCCCHHCCEEEEEC	2.73	21963094
335	Neddylation	RDINAVLIDMERQGD HHCCEEEEECHHCCC	3.68	32015554
335	Ubiquitination	RDINAVLIDMERQGD HHCCEEEEECHHCCC	3.68	32015554
342	Ubiquitination	IDMERQGDVYRQGTT EECHHCCCCCCCCCC	26.41	33845483
348	Phosphorylation	GDVYRQGTTPPIWHL CCCCCCCCCCCCCCC	27.99	29396449
349	Phosphorylation	DVYRQGTTPPIWHLT CCCCCCCCCCCCCCC	33.61	25159151
356	Phosphorylation	TPPIWHLTDKKRERM CCCCCCCCCHHHHHH	32.65	29396449
358	Ubiquitination	PIWHLTDKKRERMQI CCCCCCCHHHHHHHH	48.79	29967540
366	Ubiquitination	KRERMQIKRNTNSVP HHHHHHHHCCCCCCC	23.78	-
369	Phosphorylation	RMQIKRNTNSVPETA HHHHHCCCCCCCCCC	32.67	26714015
370	Ubiquitination	MQIKRNTNSVPETAP HHHHCCCCCCCCCCC	44.55	32015554
370 (in isoform 5)	Ubiquitination	-	44.55	21890473
371	Phosphorylation	QIKRNTNSVPETAPA HHHCCCCCCCCCCCC	36.69	101545203
374	Ubiquitination	RNTNSVPETAPAAIP CCCCCCCCCCCCCCC	56.28	22505724
375	Phosphorylation	NTNSVPETAPAAIPE CCCCCCCCCCCCCCC	31.69	26714015
384	Sumoylation	PAAIPETKRNAEFLT CCCCCCCCCCCEEEE	41.83	-
384	Acetylation	PAAIPETKRNAEFLT CCCCCCCCCCCEEEE	41.83	26051181
384	Sumoylation	PAAIPETKRNAEFLT CCCCCCCCCCCEEEE	41.83	28112733
384	Ubiquitination	PAAIPETKRNAEFLT CCCCCCCCCCCEEEE	41.83	32015554
390	Ubiquitination	TKRNAEFLTCNIPTS CCCCCEEEEEECCCC	3.93	24816145
393	Ubiquitination	NAEFLTCNIPTSNAS CCEEEEEECCCCCCC	37.73	32015554
394	Ubiquitination	AEFLTCNIPTSNASN CEEEEEECCCCCCCC	4.24	24816145
396	O-linked_Glycosylation	FLTCNIPTSNASNNM EEEEECCCCCCCCCC	30.71	30059200
397	O-linked_Glycosylation	LTCNIPTSNASNNMV EEEECCCCCCCCCCE	25.66	30059200
408	Acetylation	NNMVTTEKVENGQEP CCCEEEEEECCCCCC	53.40	26051181
408	Sumoylation	NNMVTTEKVENGQEP CCCEEEEEECCCCCC	53.40	28112733
417	Ubiquitination	ENGQEPVIKLENRQE CCCCCCEEEECCCCC	6.53	29967540
418	Sumoylation	NGQEPVIKLENRQEA CCCCCEEEECCCCCC	50.40	-
418	Sumoylation	NGQEPVIKLENRQEA CCCCCEEEECCCCCC	50.40	25114211
418	Ubiquitination	NGQEPVIKLENRQEA CCCCCEEEECCCCCC	50.40	32015554
427	Ubiquitination	ENRQEARPEPARLKP CCCCCCCCCCCCCCC	60.00	33845483
433	Ubiquitination	RPEPARLKPPVHYNG CCCCCCCCCCCCCCC	41.54	32015554
438	Phosphorylation	RLKPPVHYNGPSKAG CCCCCCCCCCCCCCC	23.27	28152594
442	Phosphorylation	PVHYNGPSKAGYVDF CCCCCCCCCCCEEEC	36.21	28152594
442	Ubiquitination	PVHYNGPSKAGYVDF CCCCCCCCCCCEEEC	36.21	32015554
443	Acetylation	VHYNGPSKAGYVDFE CCCCCCCCCCEEECC	49.30	25953088
443	Ubiquitination	VHYNGPSKAGYVDFE CCCCCCCCCCEEECC	49.30	21890473
443 (in isoform 1)	Ubiquitination	-	49.30	21890473
443 (in isoform 2)	Ubiquitination	-	49.30	21890473
443 (in isoform 3)	Ubiquitination	-	49.30	21890473
446	Phosphorylation	NGPSKAGYVDFENGQ CCCCCCCEEECCCCE	11.16	46159493
449	Ubiquitination	SKAGYVDFENGQWAT CCCCEEECCCCEEEC	5.84	21890473
450	Ubiquitination	KAGYVDFENGQWATD CCCEEECCCCEEECC	56.86	29967540
453	Ubiquitination	YVDFENGQWATDDIP EEECCCCEEECCCCC	37.91	21890473
462	Ubiquitination	ATDDIPDDLNSIRAA ECCCCCCCHHHHHCC	42.25	21890473
462	Ubiquitination	ATDDIPDDLNSIRAA ECCCCCCCHHHHHCC	42.25	21890473
462 (in isoform 5)	Ubiquitination	-	42.25	21890473
465	Phosphorylation	DIPDDLNSIRAAPGE CCCCCHHHHHCCCCC	22.28	46159469
468	Ubiquitination	DDLNSIRAAPGEFRA CCHHHHHCCCCCHHH	19.15	23000965
481	Phosphorylation	RAIMEMPSFYSHGLP HHHHCCCCHHHCCCC	35.19	21945579
483	Phosphorylation	IMEMPSFYSHGLPRC HHCCCCHHHCCCCCC	12.23	21945579
483	Ubiquitination	IMEMPSFYSHGLPRC HHCCCCHHHCCCCCC	12.23	29967540
484	Phosphorylation	MEMPSFYSHGLPRCS HCCCCHHHCCCCCCC	14.74	21945579
486	Ubiquitination	MPSFYSHGLPRCSPY CCCHHHCCCCCCCCC	31.28	21890473
486 (in isoform 4)	Ubiquitination	-	31.28	21890473
491	Phosphorylation	SHGLPRCSPYKKLTE HCCCCCCCCCCCCCH	32.32	25159151
493	Phosphorylation	GLPRCSPYKKLTECQ CCCCCCCCCCCCHHH	12.40	30576142
495	Acetylation	PRCSPYKKLTECQLK CCCCCCCCCCHHHCC	55.59	25953088
495	Ubiquitination	PRCSPYKKLTECQLK CCCCCCCCCCHHHCC	55.59	29967540
497	Phosphorylation	CSPYKKLTECQLKNP CCCCCCCCHHHCCCC	43.52	26074081
500	Phosphorylation	YKKLTECQLKNPISG CCCCCHHHCCCCHHH	49.60	32645325
503	Ubiquitination	LTECQLKNPISGLLE CCHHHCCCCHHHHHH	47.97	27667366
513 (in isoform 1)	Phosphorylation	-	33.27	-
523 (in isoform 1)	Phosphorylation	-	4.30	-
528 (in isoform 1)	Phosphorylation	-	39.18	-
530 (in isoform 1)	Phosphorylation	-	48.26	-
530	Phosphorylation	MIEQSGPPHEPRFKF ECCCCCCCCCCCEEE	48.26	32142685
536	Ubiquitination	PPHEPRFKFQVVING CCCCCCEEEEEEECC	35.85	23000965
553	Phosphorylation	FPPAEAGSKKVAKQD CCCHHCCCHHHHHHH	36.03	46159475
558	Sumoylation	AGSKKVAKQDAAMKA CCCHHHHHHHHHHHH	52.26	-
558	Sumoylation	AGSKKVAKQDAAMKA CCCHHHHHHHHHHHH	52.26	-
558	Ubiquitination	AGSKKVAKQDAAMKA CCCHHHHHHHHHHHH	52.26	29967540
564	Acetylation	AKQDAAMKAMTILLE HHHHHHHHHHHHHHH	30.22	25953088
564	Ubiquitination	AKQDAAMKAMTILLE HHHHHHHHHHHHHHH	30.22	29967540
566	Sulfoxidation	QDAAMKAMTILLEEA HHHHHHHHHHHHHHH	1.68	21406390
567	Phosphorylation	DAAMKAMTILLEEAK HHHHHHHHHHHHHHH	17.21	36012753
574	Sumoylation	TILLEEAKAKDSGKS HHHHHHHHHHHCCCC	60.28	-
574	Acetylation	TILLEEAKAKDSGKS HHHHHHHHHHHCCCC	60.28	25953088
574	Sumoylation	TILLEEAKAKDSGKS HHHHHHHHHHHCCCC	60.28	-
574	Ubiquitination	TILLEEAKAKDSGKS HHHHHHHHHHHCCCC	60.28	29967540
576	Ubiquitination	LLEEAKAKDSGKSEE HHHHHHHHHCCCCCC	52.28	-
578	Phosphorylation	EEAKAKDSGKSEESS HHHHHHHCCCCCCHH	47.62	23312004
580	Sumoylation	AKAKDSGKSEESSHY HHHHHCCCCCCHHCC	59.66	-
580	Sumoylation	AKAKDSGKSEESSHY HHHHHCCCCCCHHCC	59.66	28112733
580	Ubiquitination	AKAKDSGKSEESSHY HHHHHCCCCCCHHCC	59.66	29967540
581	Phosphorylation	KAKDSGKSEESSHYS HHHHCCCCCCHHCCC	50.55	25002506
584	Phosphorylation	DSGKSEESSHYSTEK HCCCCCCHHCCCCHH	20.54	25002506
585	Phosphorylation	SGKSEESSHYSTEKE CCCCCCHHCCCCHHH	29.71	28796482
587	Phosphorylation	KSEESSHYSTEKESE CCCCHHCCCCHHHHH	21.16	28796482
588	Phosphorylation	SEESSHYSTEKESEK CCCHHCCCCHHHHHH	25.35	113311157
589	Phosphorylation	EESSHYSTEKESEKT CCHHCCCCHHHHHHC	43.86	28796482
591	Ubiquitination	SSHYSTEKESEKTAE HHCCCCHHHHHHCCC	67.63	33845483
593	Phosphorylation	HYSTEKESEKTAESQ CCCCHHHHHHCCCCC	56.30	26074081
595	Ubiquitination	STEKESEKTAESQTP CCHHHHHHCCCCCCC	63.41	21906983
595 (in isoform 1)	Ubiquitination	-	63.41	21890473
595 (in isoform 2)	Ubiquitination	-	63.41	21890473
595 (in isoform 3)	Ubiquitination	-	63.41	21890473
596	Phosphorylation	TEKESEKTAESQTPT CHHHHHHCCCCCCCC	31.44	30266825
596 (in isoform 2)	Phosphorylation	-	31.44	21406692
599	Phosphorylation	ESEKTAESQTPTPSA HHHHCCCCCCCCCCH	36.57	25159151
600	Ubiquitination	SEKTAESQTPTPSAT HHHCCCCCCCCCCHH	42.90	33845483
601	Phosphorylation	EKTAESQTPTPSATS HHCCCCCCCCCCHHH	38.11	29255136
601 (in isoform 2)	Phosphorylation	-	38.11	21406692
603	Phosphorylation	TAESQTPTPSATSFF CCCCCCCCCCHHHHC	33.01	25159151
605	Phosphorylation	ESQTPTPSATSFFSG CCCCCCCCHHHHCCC	46.81	30266825
605 (in isoform 2)	Phosphorylation	-	46.81	21406692
607	Phosphorylation	QTPTPSATSFFSGKS CCCCCCHHHHCCCCC	30.33	30266825
608	Phosphorylation	TPTPSATSFFSGKSP CCCCCHHHHCCCCCC	24.82	30266825
610	Phosphorylation	TPSATSFFSGKSPVT CCCHHHHCCCCCCHH	10.62	33259812
611	Phosphorylation	PSATSFFSGKSPVTT CCHHHHCCCCCCHHH	43.21	28176443
612	Phosphorylation	SATSFFSGKSPVTTL CHHHHCCCCCCHHHH	29.33	32142685
613	Acetylation	ATSFFSGKSPVTTLL HHHHCCCCCCHHHHH	50.84	25953088
613	Ubiquitination	ATSFFSGKSPVTTLL HHHHCCCCCCHHHHH	50.84	29967540
614	Phosphorylation	TSFFSGKSPVTTLLE HHHCCCCCCHHHHHH	28.29	22167270
614 (in isoform 2)	Phosphorylation	-	28.29	21406692
615	Ubiquitination	SFFSGKSPVTTLLEC HHCCCCCCHHHHHHH	30.84	27667366
617	Phosphorylation	FSGKSPVTTLLECMH CCCCCCHHHHHHHHH	18.34	30266825
618	Phosphorylation	SGKSPVTTLLECMHK CCCCCHHHHHHHHHH	29.58	30266825
618 (in isoform 2)	Phosphorylation	-	29.58	21406692
622	Glutathionylation	PVTTLLECMHKLGNS CHHHHHHHHHHHCCC	3.32	22555962
623	Phosphorylation	VTTLLECMHKLGNSC HHHHHHHHHHHCCCC	1.97	32142685
623	Ubiquitination	VTTLLECMHKLGNSC HHHHHHHHHHHCCCC	1.97	33845483
625	Acetylation	TLLECMHKLGNSCEF HHHHHHHHHCCCCEE	31.07	25953088
625	Ubiquitination	TLLECMHKLGNSCEF HHHHHHHHHCCCCEE	31.07	21963094
629	Phosphorylation	CMHKLGNSCEFRLLS HHHHHCCCCEEEEEC	17.15	25159151
631	Ubiquitination	HKLGNSCEFRLLSKE HHHCCCCEEEEECCC	33.35	21963094
635	Ubiquitination	NSCEFRLLSKEGPAH CCCEEEEECCCCCCC	6.31	21963094
636	Phosphorylation	SCEFRLLSKEGPAHE CCEEEEECCCCCCCC	33.00	23186163
637	Ubiquitination	CEFRLLSKEGPAHEP CEEEEECCCCCCCCC	67.66	33845483
638 (in isoform 4)	Ubiquitination	-	68.01	21890473
641	Ubiquitination	LLSKEGPAHEPKFQY EECCCCCCCCCCCCE	30.45	27667366
645	Acetylation	EGPAHEPKFQYCVAV CCCCCCCCCCEEEEE	41.96	26051181
646	Ubiquitination	GPAHEPKFQYCVAVG CCCCCCCCCEEEEEC	10.28	33845483
648	Phosphorylation	AHEPKFQYCVAVGAQ CCCCCCCEEEEECCC	7.63	28152594
649	Ubiquitination	HEPKFQYCVAVGAQT CCCCCCEEEEECCCC	0.80	32015554
653	Ubiquitination	FQYCVAVGAQTFPSV CCEEEEECCCCCCCC	11.39	29967540
665	Acetylation	PSVSAPSKKVAKQMA CCCCCCCHHHHHHHH	50.65	25953088
665	Ubiquitination	PSVSAPSKKVAKQMA CCCCCCCHHHHHHHH	50.65	21906983
665 (in isoform 1)	Ubiquitination	-	50.65	21890473
665 (in isoform 2)	Ubiquitination	-	50.65	21890473
665 (in isoform 3)	Ubiquitination	-	50.65	21890473
666	Acetylation	SVSAPSKKVAKQMAA CCCCCCHHHHHHHHH	52.33	25953088
666	Ubiquitination	SVSAPSKKVAKQMAA CCCCCCHHHHHHHHH	52.33	-
668	Ubiquitination	SAPSKKVAKQMAAEE CCCCHHHHHHHHHHH	12.78	21963094
669	Sumoylation	APSKKVAKQMAAEEA CCCHHHHHHHHHHHH	43.52	-
669	2-Hydroxyisobutyrylation	APSKKVAKQMAAEEA CCCHHHHHHHHHHHH	43.52	-
669	Acetylation	APSKKVAKQMAAEEA CCCHHHHHHHHHHHH	43.52	25953088
669	Sumoylation	APSKKVAKQMAAEEA CCCHHHHHHHHHHHH	43.52	-
669	Ubiquitination	APSKKVAKQMAAEEA CCCHHHHHHHHHHHH	43.52	22505724
674	Ubiquitination	VAKQMAAEEAMKALH HHHHHHHHHHHHHHH	36.43	32015554
675	Ubiquitination	AKQMAAEEAMKALHG HHHHHHHHHHHHHHH	49.70	22505724
679	Ubiquitination	AAEEAMKALHGEATN HHHHHHHHHHHHHHH	7.54	22505724
685	Phosphorylation	KALHGEATNSMASDN HHHHHHHHHHCCCCC	24.43	28176443
685 (in isoform 3)	Phosphorylation	-	24.43	27762562
687	Phosphorylation	LHGEATNSMASDNQP HHHHHHHHCCCCCCC	16.03	28176443
687 (in isoform 3)	Phosphorylation	-	16.03	27762562
690	Phosphorylation	EATNSMASDNQPEGM HHHHHCCCCCCCCCC	28.58	28176443
690 (in isoform 3)	Phosphorylation	-	28.58	27762562
699	Phosphorylation	NQPEGMISESLDNLE CCCCCCCCHHHHHHH	16.55	30108239
701	Phosphorylation	PEGMISESLDNLESM CCCCCCHHHHHHHHH	33.94	30108239
701	Ubiquitination	PEGMISESLDNLESM CCCCCCHHHHHHHHH	33.94	29967540
707	Phosphorylation	ESLDNLESMMPNKVR HHHHHHHHHCCHHHH	24.44	30108239
708	Ubiquitination	SLDNLESMMPNKVRK HHHHHHHHCCHHHHH	3.65	29967540
708 (in isoform 4)	Ubiquitination	-	3.65	21890473
712	Ubiquitination	LESMMPNKVRKIGEL HHHHCCHHHHHHHHH	37.23	22505724
712 (in isoform 4)	Ubiquitination	-	37.23	-
715	Ubiquitination	MMPNKVRKIGELVRY HCCHHHHHHHHHHHH	59.04	-
722	Phosphorylation	KIGELVRYLNTNPVG HHHHHHHHHHCCCCC	9.23	11315449
726	Ubiquitination	LVRYLNTNPVGGLLE HHHHHHCCCCCHHHH	28.34	29967540
734	Phosphorylation	PVGGLLEYARSHGFA CCCHHHHHHHHCCCE	13.79	11315459
738	Ubiquitination	LLEYARSHGFAAEFK HHHHHHHCCCEEEEE	29.81	21890473
738 (in isoform 3)	Ubiquitination	-	29.81	21890473
744	Ubiquitination	SHGFAAEFKLVDQSG HCCCEEEEEEECCCC	6.77	23000965
745	Acetylation	HGFAAEFKLVDQSGP CCCEEEEEEECCCCC	38.82	26051181
745	Ubiquitination	HGFAAEFKLVDQSGP CCCEEEEEEECCCCC	38.82	29967540
750	Phosphorylation	EFKLVDQSGPPHEPK EEEEECCCCCCCCCC	49.13	28555341
757	Acetylation	SGPPHEPKFVYQAKV CCCCCCCCEEEEEEE	44.47	23749302
757	Malonylation	SGPPHEPKFVYQAKV CCCCCCCCEEEEEEE	44.47	26320211
757	Ubiquitination	SGPPHEPKFVYQAKV CCCCCCCCEEEEEEE	44.47	23000965
757 (in isoform 1)	Ubiquitination	-	44.47	21890473
757 (in isoform 2)	Ubiquitination	-	44.47	21890473
759	Ubiquitination	PPHEPKFVYQAKVGG CCCCCCEEEEEEECC	4.29	29967540
762	Ubiquitination	EPKFVYQAKVGGRWF CCCEEEEEEECCEEE	7.27	29967540
763	2-Hydroxyisobutyrylation	PKFVYQAKVGGRWFP CCEEEEEEECCEEEC	26.36	-
763	Acetylation	PKFVYQAKVGGRWFP CCEEEEEEECCEEEC	26.36	25953088
763	Ubiquitination	PKFVYQAKVGGRWFP CCEEEEEEECCEEEC	26.36	23000965
767	Ubiquitination	YQAKVGGRWFPAVCA EEEEECCEEECCCHH	26.40	21890473
769	Ubiquitination	AKVGGRWFPAVCAHS EEECCEEECCCHHCC	2.41	23000965
773	Ubiquitination	GRWFPAVCAHSKKQG CEEECCCHHCCHHHC	2.83	23000965
777	Acetylation	PAVCAHSKKQGKQEA CCCHHCCHHHCHHHH	38.97	26051181
778	Ubiquitination	AVCAHSKKQGKQEAA CCHHCCHHHCHHHHH	68.26	29967540
779	Ubiquitination	VCAHSKKQGKQEAAD CHHCCHHHCHHHHHH	68.96	24816145
781	Ubiquitination	AHSKKQGKQEAADAA HCCHHHCHHHHHHHH	42.33	29967540
786 (in isoform 3)	Phosphorylation	-	39.15	20068231
791 (in isoform 3)	Phosphorylation	-	4.80	20068231
793 (in isoform 3)	Phosphorylation	-	6.26	20068231
794	Ubiquitination	AALRVLIGENEKAER HHHHHHHCCCHHHHH	27.76	33845483
794 (in isoform 3)	Phosphorylation	-	27.76	20068231
798	Acetylation	VLIGENEKAERMGFT HHHCCCHHHHHCCCC	68.10	23749302
798	Ubiquitination	VLIGENEKAERMGFT HHHCCCHHHHHCCCC	68.10	27667366
800	Ubiquitination	IGENEKAERMGFTEV HCCCHHHHHCCCCEE	55.02	21890473
800 (in isoform 4)	Ubiquitination	-	55.02	21890473
804	Ubiquitination	EKAERMGFTEVTPVT HHHHHCCCCEEECCC	3.73	24816145
805	Phosphorylation	KAERMGFTEVTPVTG HHHHCCCCEEECCCC	24.66	29255136
805 (in isoform 2)	Phosphorylation	-	24.66	20068231
806	Ubiquitination	AERMGFTEVTPVTGA HHHCCCCEEECCCCH	41.98	23000965
807	Ubiquitination	ERMGFTEVTPVTGAS HHCCCCEEECCCCHH	7.14	33845483
808	Phosphorylation	RMGFTEVTPVTGASL HCCCCEEECCCCHHH	13.05	29255136
808	Ubiquitination	RMGFTEVTPVTGASL HCCCCEEECCCCHHH	13.05	24816145
810 (in isoform 2)	Phosphorylation	-	5.87	20068231
811	O-linked_Glycosylation	FTEVTPVTGASLRRT CCEEECCCCHHHHHH	28.38	30059200
811	Phosphorylation	FTEVTPVTGASLRRT CCEEECCCCHHHHHH	28.38	29255136
812 (in isoform 2)	Phosphorylation	-	17.25	20068231
813 (in isoform 2)	Phosphorylation	-	8.95	20068231
814	Phosphorylation	VTPVTGASLRRTMLL EECCCCHHHHHHHHH	24.61	29255136
818	Phosphorylation	TGASLRRTMLLLSRS CCHHHHHHHHHHHCC	13.02	23927012
819	Sulfoxidation	GASLRRTMLLLSRSP CHHHHHHHHHHHCCC	2.05	21406390
820	Ubiquitination	ASLRRTMLLLSRSPE HHHHHHHHHHHCCCC	4.26	33845483
823	Phosphorylation	RRTMLLLSRSPEAQP HHHHHHHHCCCCCCC	30.59	23927012
825	Phosphorylation	TMLLLSRSPEAQPKT HHHHHHCCCCCCCCC	24.58	25159151
831	Ubiquitination	RSPEAQPKTLPLTGS CCCCCCCCCCCCCCC	51.09	23000965
832	Phosphorylation	SPEAQPKTLPLTGST CCCCCCCCCCCCCCC	40.05	28555341
834	Phosphorylation	EAQPKTLPLTGSTFH CCCCCCCCCCCCCHH	32.86	32142685
837	Ubiquitination	PKTLPLTGSTFHDQI CCCCCCCCCCHHHHH	32.16	23000965
841	Ubiquitination	PLTGSTFHDQIAMLS CCCCCCHHHHHHHHH	26.59	23000965
841 (in isoform 4)	Ubiquitination	-	26.59	-
850	Ubiquitination	QIAMLSHRCFNTLTN HHHHHHHHHHHHHCC	24.28	29967540
866	Ubiquitination	FQPSLLGRKILAAII CCHHHHHHHHHHHHH	23.86	24816145
866 (in isoform 4)	Phosphorylation	-	23.86	21406692
868 (in isoform 4)	Phosphorylation	-	2.81	21406692
869	Ubiquitination	SLLGRKILAAIIMKK HHHHHHHHHHHHCCC	2.71	29967540
874	Ubiquitination	KILAAIIMKKDSEDM HHHHHHHCCCCCCCC	3.45	23000965
875	Sumoylation	ILAAIIMKKDSEDMG HHHHHHCCCCCCCCC	42.91	28112733
878	Phosphorylation	AIIMKKDSEDMGVVV HHHCCCCCCCCCEEE	44.36	29978859
881	Sulfoxidation	MKKDSEDMGVVVSLG CCCCCCCCCEEEEEC	3.73	21406390
886	Phosphorylation	EDMGVVVSLGTGNRC CCCCEEEEECCCCCE	14.96	29978859
889	Phosphorylation	GVVVSLGTGNRCVKG CEEEEECCCCCEECC	36.25	29978859
891	Ubiquitination	VVSLGTGNRCVKGDS EEEECCCCCEECCCC	33.73	27667366
892	Ubiquitination	VSLGTGNRCVKGDSL EEECCCCCEECCCCC	28.13	24816145
895	Acetylation	GTGNRCVKGDSLSLK CCCCCEECCCCCCCC	61.70	26051181
895	Ubiquitination	GTGNRCVKGDSLSLK CCCCCEECCCCCCCC	61.70	29967540
898	Phosphorylation	NRCVKGDSLSLKGET CCEECCCCCCCCCCC	28.64	24719451
899	Ubiquitination	RCVKGDSLSLKGETV CEECCCCCCCCCCCH	9.16	32015554
900	Phosphorylation	CVKGDSLSLKGETVN EECCCCCCCCCCCHH	31.80	24719451
901	Ubiquitination	VKGDSLSLKGETVND ECCCCCCCCCCCHHH	11.37	29967540
902	Acetylation	KGDSLSLKGETVNDC CCCCCCCCCCCHHHH	51.85	23749302
902	Malonylation	KGDSLSLKGETVNDC CCCCCCCCCCCHHHH	51.85	26320211
903	Ubiquitination	GDSLSLKGETVNDCH CCCCCCCCCCHHHHH	40.89	29967540
910	Ubiquitination	GETVNDCHAEIISRR CCCHHHHHHHHHHHH	29.29	27667366
918	Ubiquitination	AEIISRRGFIRFLYS HHHHHHHHHHHHHHH	22.63	32015554
919	Ubiquitination	EIISRRGFIRFLYSE HHHHHHHHHHHHHHH	3.25	29967540
922	Ubiquitination	SRRGFIRFLYSELMK HHHHHHHHHHHHHHH	6.84	29967540
924	Phosphorylation	RGFIRFLYSELMKYN HHHHHHHHHHHHHHC	9.44	21406692
924	Ubiquitination	RGFIRFLYSELMKYN HHHHHHHHHHHHHHC	9.44	29967540
925	Phosphorylation	GFIRFLYSELMKYNS HHHHHHHHHHHHHCC	26.80	21406692
929	Acetylation	FLYSELMKYNSQTAK HHHHHHHHHCCCCCC	54.63	26051181
936	Ubiquitination	KYNSQTAKDSIFEPA HHCCCCCCCCCCCCC	56.23	27667366
942	Ubiquitination	AKDSIFEPAKGGEKL CCCCCCCCCCCCCEE	28.64	27667366
944	Acetylation	DSIFEPAKGGEKLQI CCCCCCCCCCCEEEE	77.49	26051181
944	Malonylation	DSIFEPAKGGEKLQI CCCCCCCCCCCEEEE	77.49	26320211
944	Ubiquitination	DSIFEPAKGGEKLQI CCCCCCCCCCCEEEE	77.49	32015554
946	Ubiquitination	IFEPAKGGEKLQIKK CCCCCCCCCEEEEEE	28.32	27667366
948	Ubiquitination	EPAKGGEKLQIKKTV CCCCCCCEEEEEEEE	49.30	29967540
951	Ubiquitination	KGGEKLQIKKTVSFH CCCCEEEEEEEEEEE	7.77	29967540
953	Ubiquitination	GEKLQIKKTVSFHLY CCEEEEEEEEEEEEE	56.65	33845483
958	Ubiquitination	IKKTVSFHLYISTAP EEEEEEEEEEEEECC	15.37	29967540
970	Ubiquitination	TAPCGDGALFDKSCS ECCCCCCCEECCCCC	15.14	29967540
975	Phosphorylation	DGALFDKSCSDRAME CCCEECCCCCHHHHH	22.24	50563583
977	Ubiquitination	ALFDKSCSDRAMEST CEECCCCCHHHHHCC	36.90	29967540
979	Ubiquitination	FDKSCSDRAMESTES ECCCCCHHHHHCCCC	21.38	27667366
986	Phosphorylation	RAMESTESRHYPVFE HHHHCCCCCCCCCCC	25.17	50563591
989	Phosphorylation	ESTESRHYPVFENPK HCCCCCCCCCCCCCC	10.44	28442448
996	Ubiquitination	YPVFENPKQGKLRTK CCCCCCCCCCCEEEE	81.11	29967540
1003	Sumoylation	KQGKLRTKVENGEGT CCCCEEEEEECCCCE	40.91	-
1003	Sumoylation	KQGKLRTKVENGEGT CCCCEEEEEECCCCE	40.91	-
1003	Ubiquitination	KQGKLRTKVENGEGT CCCCEEEEEECCCCE	40.91	29967540
1033	Phosphorylation	RLGERLRTMSCSDKI ECCHHHHHCCCCHHH	20.30	23836654
1035	Phosphorylation	GERLRTMSCSDKILR CHHHHHCCCCHHHHH	15.17	23836654
1037	Phosphorylation	RLRTMSCSDKILRWN HHHHCCCCHHHHHHH	34.33	23836654
1039	Acetylation	RTMSCSDKILRWNVL HHCCCCHHHHHHHHH	27.61	25953088
1066	Phosphorylation	PIYLKSVTLGYLFSQ HHHCHHCHHHHHHCC	22.89	28152594
1069	Phosphorylation	LKSVTLGYLFSQGHL CHHCHHHHHHCCCCC	14.00	28152594
1070	Ubiquitination	KSVTLGYLFSQGHLT HHCHHHHHHCCCCCC	2.94	33845483
1072	Phosphorylation	VTLGYLFSQGHLTRA CHHHHHHCCCCCCEE	32.43	28152594
1089	Phosphorylation	CRVTRDGSAFEDGLR EEECCCCCCCCCCCC	33.79	20873877
1089	Ubiquitination	CRVTRDGSAFEDGLR EEECCCCCCCCCCCC	33.79	33845483
1096	Methylation	SAFEDGLRHPFIVNH CCCCCCCCCCEECCC	40.75	-
1105	Acetylation	PFIVNHPKVGRVSIY CEECCCCCCCEEEEE	50.17	26051181
1110	Phosphorylation	HPKVGRVSIYDSKRQ CCCCCEEEEEECCCC	17.67	28450419
1112	Phosphorylation	KVGRVSIYDSKRQSG CCCEEEEEECCCCCC	13.47	29496907
1114	Phosphorylation	GRVSIYDSKRQSGKT CEEEEEECCCCCCCC	16.86	28450419
1115	2-Hydroxyisobutyrylation	RVSIYDSKRQSGKTK EEEEEECCCCCCCCC	52.11	-
1115	Acetylation	RVSIYDSKRQSGKTK EEEEEECCCCCCCCC	52.11	25953088
1115	Ubiquitination	RVSIYDSKRQSGKTK EEEEEECCCCCCCCC	52.11	33845483
1121	Ubiquitination	SKRQSGKTKETSVNW CCCCCCCCCCCEEEE	37.32	24816145
1124	Ubiquitination	QSGKTKETSVNWCLA CCCCCCCCEEEEEEC	39.26	33845483
1125	Ubiquitination	SGKTKETSVNWCLAD CCCCCCCEEEEEECC	17.97	24816145
1142	Ubiquitination	DLEILDGTRGTVDGP CEEEECCCCCCCCCC	26.12	24816145
1151	Ubiquitination	GTVDGPRNELSRVSK CCCCCCHHHHHHHHH	58.66	29967540
1158	Ubiquitination	NELSRVSKKNIFLLF HHHHHHHHHHHHHHH	47.16	24816145
1158 (in isoform 4)	Ubiquitination	-	47.16	-
1159	Acetylation	ELSRVSKKNIFLLFK HHHHHHHHHHHHHHH	48.01	23749302
1161	Ubiquitination	SRVSKKNIFLLFKKL HHHHHHHHHHHHHHH	3.36	24816145
1166	2-Hydroxyisobutyrylation	KNIFLLFKKLCSFRY HHHHHHHHHHHCHHH	44.82	-
1166	Acetylation	KNIFLLFKKLCSFRY HHHHHHHHHHHCHHH	44.82	25953088
1166	Ubiquitination	KNIFLLFKKLCSFRY HHHHHHHHHHHCHHH	44.82	-
1169	Ubiquitination	FLLFKKLCSFRYRRD HHHHHHHHCHHHHHH	5.05	29967540
1170	Phosphorylation	LLFKKLCSFRYRRDL HHHHHHHCHHHHHHH	24.16	24719451
1170	Ubiquitination	LLFKKLCSFRYRRDL HHHHHHHCHHHHHHH	24.16	29967540
1174	Ubiquitination	KLCSFRYRRDLLRLS HHHCHHHHHHHHHHH	22.75	29967540
1187	Ubiquitination	LSYGEAKKAARDYET HHHHHHHHHHHHHHH	55.09	24816145
1188	Ubiquitination	SYGEAKKAARDYETA HHHHHHHHHHHHHHH	13.66	29967540
1193	Ubiquitination	KKAARDYETAKNYFK HHHHHHHHHHHHHHH	46.72	24816145
1196	Acetylation	ARDYETAKNYFKKGL HHHHHHHHHHHHHCH	60.65	27452117
1196	Ubiquitination	ARDYETAKNYFKKGL HHHHHHHHHHHHHCH	60.65	29967540
1197	Ubiquitination	RDYETAKNYFKKGLK HHHHHHHHHHHHCHH	45.04	24816145
1214	Acetylation	GYGNWISKPQEEKNF CCCCCCCCCHHHCCC	41.40	26051181
1214	Ubiquitination	GYGNWISKPQEEKNF CCCCCCCCCHHHCCC	41.40	29967540
1219	Ubiquitination	ISKPQEEKNFYLCPV CCCCHHHCCCEECCC	52.16	29967540
1222	Phosphorylation	PQEEKNFYLCPV--- CHHHCCCEECCC---	19.45	28152594
1230	Ubiquitination	LCPV----------- ECCC-----------		24816145

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DSRAD_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DSRAD_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DSRAD_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
XPO1_HUMAN	XPO1	physical	11604520
HNRPM_HUMAN	HNRNPM	physical	22939629
RENT1_HUMAN	UPF1	physical	18362360
TGM2_HUMAN	TGM2	physical	21988832

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 127400: Dyschromatosis symmetrica hereditaria (DSH)
• 615010: Aicardi-Goutieres syndrome 6 (AGS6)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-601; SER-614; SER-823AND SER-825, AND MASS SPECTROMETRY.
PubMed: 18669648

"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle.";
Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.;
Mol. Cell 31:438-448(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-825, AND MASSSPECTROMETRY.
PubMed: 18691976

"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-808 AND SER-825, ANDMASS SPECTROMETRY.
PubMed: 17924679

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-601; THR-603 ANDTHR-808, AND MASS SPECTROMETRY.
PubMed: 19690332

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-601 AND THR-808, ANDMASS SPECTROMETRY.
PubMed: 19413330

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-808, AND MASSSPECTROMETRY.
PubMed: 18220336

"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-808, AND MASSSPECTROMETRY.
PubMed: 16964243

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-818, AND MASSSPECTROMETRY.
PubMed: 17081983

Sumoylation

"SUMO-1 modification alters ADAR1 editing activity.";
Desterro J.M.P., Keegan L.P., Jaffray E., Hay R.T., O'Connell M.A.,Carmo-Fonseca M.;
Mol. Biol. Cell 16:5115-5126(2005).
Cited for: SUMOYLATION AT LYS-418, AND MUTAGENESIS OF LYS-418.
PubMed: 16120648