ILVBL_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ILVBL_HUMAN
• UniProt AC: A1L0T0
• Protein Name: Acetolactate synthase-like protein
• Gene Name: ILVBL
• Organism: Homo sapiens (Human).
• Sequence Length: 632
• Subcellular Localization: Membrane; Single-pass membrane protein.
• Protein Sequence: METPAAAAPAGSLFPSFLLLACGTLVAALLGAAHRLGLFYQLLHKVDKASVRHGGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLCKFCVSVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEILSRAKRPLMVLGSQALLTPTSADKLRAAVETLGVPCFLGGMARGLLGRNHPLHIRENRSAALKKADVIVLAGTVCDFRLSYGRVLSHSSKIIIVNRNREEMLLNSDIFWKPQEAVQGDVGSFVLKLVEGLQGQTWAPDWVEELREADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCRPDAEVWCLFGDGAFGYSLIEFDTFVRHKIPVMALVGNDAGWTQISREQVPSLGSNVACGLAYTDYHKAAMGLGARGLLLSRENEDQVVKVLHDAQQQCRDGHPVVVNILIGRTDFRDGSIAV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
227	Acetylation	QKEMVPAKPPKGLVG ECCCCCCCCCCCHHH	56.64	25953088
577 (in isoform 1)	Ubiquitination	-	31.45	21890473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ILVBL_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ILVBL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ILVBL_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
XRCC6_HUMAN	XRCC6	physical	16169070
RAB14_HUMAN	RAB14	physical	22939629
SRSF1_HUMAN	SRSF1	physical	22939629
TOM1_HUMAN	TOM1	physical	21988832
CEP76_HUMAN	CEP76	physical	25416956
AT1B1_HUMAN	ATP1B1	physical	26344197
CY1_HUMAN	CYC1	physical	26344197
DHB14_HUMAN	HSD17B14	physical	26344197
MTCH1_HUMAN	MTCH1	physical	26344197
NDUS3_HUMAN	NDUFS3	physical	26344197
RAB1A_HUMAN	RAB1A	physical	26344197
UCRI_HUMAN	UQCRFS1	physical	26344197
GBA2_HUMAN	GBA2	physical	28514442
OSBL6_HUMAN	OSBPL6	physical	28514442
OSBL3_HUMAN	OSBPL3	physical	28514442
THADA_HUMAN	THADA	physical	28514442
XPO6_HUMAN	XPO6	physical	28514442
INT12_HUMAN	INTS12	physical	28514442
INT1_HUMAN	INTS1	physical	28514442
XPO4_HUMAN	XPO4	physical	28514442
COG7_HUMAN	COG7	physical	28514442
PGTA_HUMAN	RABGGTA	physical	28514442
EI2BE_HUMAN	EIF2B5	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.