| UniProt ID | MTCH1_HUMAN | |
|---|---|---|
| UniProt AC | Q9NZJ7 | |
| Protein Name | Mitochondrial carrier homolog 1 | |
| Gene Name | MTCH1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 389 | |
| Subcellular Localization |
Mitochondrion inner membrane Multi-pass membrane protein . |
|
| Protein Description | Potential mitochondrial transporter. May play a role in apoptosis.. | |
| Protein Sequence | MGASDPEVAPWARGGAAGMAGAGAGAGARGGAAAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGGSGGLGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | Phosphorylation | ----MGASDPEVAPW ----CCCCCCCCHHH | 48.22 | 20860994 | |
| 29 | Methylation | AGAGAGARGGAAAGV CCCCCCCCCCHHCCC | 43.06 | 24129315 | |
| 61 | Phosphorylation | PRPAAQPSARRMDGG CCCCCCCCCCCCCCC | 23.48 | 24670416 | |
| 96 | Phosphorylation | GAGVTALSHPLLYVK CCCHHHCCCHHHHHH | 22.16 | - | |
| 125 (in isoform 2) | Ubiquitination | - | 34.49 | 21890473 | |
| 125 (in isoform 1) | Ubiquitination | - | 34.49 | 21890473 | |
| 125 | Ubiquitination | GTNVLGRKVLYLPSF CCCCCCCEEEECCCC | 34.49 | 21890473 | |
| 128 | Phosphorylation | VLGRKVLYLPSFFTY CCCCEEEECCCCHHC | 21.39 | - | |
| 153 | Phosphorylation | IGLFRGLSPRLMSNA CCCCCCCCHHHHHHH | 15.70 | 22210691 | |
| 157 | Sulfoxidation | RGLSPRLMSNALSTV CCCCHHHHHHHHHHC | 2.83 | 21406390 | |
| 158 | Phosphorylation | GLSPRLMSNALSTVT CCCHHHHHHHHHHCC | 24.44 | 20068231 | |
| 162 | Phosphorylation | RLMSNALSTVTRGSM HHHHHHHHHCCCCCC | 20.58 | 22210691 | |
| 163 | Phosphorylation | LMSNALSTVTRGSMK HHHHHHHHCCCCCCC | 27.09 | 20860994 | |
| 165 | Phosphorylation | SNALSTVTRGSMKKV HHHHHHCCCCCCCCC | 29.42 | 20068231 | |
| 168 | Phosphorylation | LSTVTRGSMKKVFPP HHHCCCCCCCCCCCH | 24.92 | 22210691 | |
| 170 | Acetylation | TVTRGSMKKVFPPDE HCCCCCCCCCCCHHH | 47.70 | 26051181 | |
| 171 | Ubiquitination | VTRGSMKKVFPPDEI CCCCCCCCCCCHHHH | 40.23 | - | |
| 182 | Phosphorylation | PDEIEQVSNKDDMKT HHHHHHHCCHHHHHH | 37.54 | 26074081 | |
| 184 | Ubiquitination | EIEQVSNKDDMKTSL HHHHHCCHHHHHHHH | 47.82 | - | |
| 184 | Acetylation | EIEQVSNKDDMKTSL HHHHHCCHHHHHHHH | 47.82 | 26051181 | |
| 188 | Ubiquitination | VSNKDDMKTSLKKVV HCCHHHHHHHHHHHH | 41.79 | - | |
| 189 | Phosphorylation | SNKDDMKTSLKKVVK CCHHHHHHHHHHHHH | 32.43 | 26074081 | |
| 190 | Phosphorylation | NKDDMKTSLKKVVKE CHHHHHHHHHHHHHH | 32.45 | 26074081 | |
| 198 | Phosphorylation | LKKVVKETSYEMMMQ HHHHHHHCHHHHHHH | 30.78 | 26074081 | |
| 199 | Phosphorylation | KKVVKETSYEMMMQC HHHHHHCHHHHHHHH | 21.86 | 26074081 | |
| 200 | Phosphorylation | KVVKETSYEMMMQCV HHHHHCHHHHHHHHH | 18.44 | 26074081 | |
| 232 | 2-Hydroxyisobutyrylation | QFVGREAKYSGVLSS HHHCCHHHHHHHHHH | 34.89 | - | |
| 364 (in isoform 2) | Phosphorylation | - | 14.87 | 24719451 | |
| 381 | Phosphorylation | SLLFRRVSSGSCFAL CEEEEECCCCCCEEC | 27.46 | 30266825 | |
| 382 | Phosphorylation | LLFRRVSSGSCFALE EEEEECCCCCCEECC | 31.69 | 30266825 | |
| 384 | Phosphorylation | FRRVSSGSCFALE-- EEECCCCCCEECC-- | 14.17 | 30266825 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MTCH1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MTCH1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MTCH1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| AT1A1_HUMAN | ATP1A1 | physical | 26344197 | |
| ATPD_HUMAN | ATP5D | physical | 26344197 | |
| VA0D1_HUMAN | ATP6V0D1 | physical | 26344197 | |
| NDUS1_HUMAN | NDUFS1 | physical | 26344197 | |
| NDUV1_HUMAN | NDUFV1 | physical | 26344197 | |
| PRS7_HUMAN | PSMC2 | physical | 26344197 | |
| PRS6A_HUMAN | PSMC3 | physical | 26344197 | |
| PSMD2_HUMAN | PSMD2 | physical | 26344197 | |
| RPN1_HUMAN | RPN1 | physical | 26344197 | |
| TOM22_HUMAN | TOMM22 | physical | 26344197 | |
| TPM3_HUMAN | TPM3 | physical | 26344197 | |
| VDAC1_HUMAN | VDAC1 | physical | 26344197 | |
| VDAC2_HUMAN | VDAC2 | physical | 26344197 | |
| VDAC3_HUMAN | VDAC3 | physical | 26344197 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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