ARMX5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARMX5_HUMAN
• UniProt AC: Q6P1M9
• Protein Name: Armadillo repeat-containing X-linked protein 5
• Gene Name: ARMCX5
• Organism: Homo sapiens (Human).
• Sequence Length: 558
• Protein Sequence: MVDSGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWSRARYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPEVRDKVIRLILKL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Ubiquitination	TEARARGKAEAGLQD HHHHHHCCHHHCCCC	37.18	21906983
23	Phosphorylation	AGLQDGISGPATARV HCCCCCCCCCCEEEE	44.23	23403867
45	Ubiquitination	AVAEAELKTESVTQA HHHHHHHCCCCCCCC	41.57	21906983
46	Phosphorylation	VAEAELKTESVTQAK HHHHHHCCCCCCCCC	46.23	-
50	Phosphorylation	ELKTESVTQAKAGDG HHCCCCCCCCCCCCC	31.89	-
53	Ubiquitination	TESVTQAKAGDGAMT CCCCCCCCCCCCCCC	42.98	21906983
60	Phosphorylation	KAGDGAMTRTHTVTY CCCCCCCCEEEECCH	31.70	29978859
62	Phosphorylation	GDGAMTRTHTVTYRE CCCCCCEEEECCHHH	16.84	29978859
64	Phosphorylation	GAMTRTHTVTYREAM CCCCEEEECCHHHHH	17.58	29978859
66	Phosphorylation	MTRTHTVTYREAMAV CCEEEECCHHHHHHH	20.30	29978859
67	Phosphorylation	TRTHTVTYREAMAVT CEEEECCHHHHHHHE	11.34	29978859
74	Phosphorylation	YREAMAVTREVIKVE HHHHHHHEEEEEECC	16.15	29978859
93	Ubiquitination	TRVMVETKTKPLAER EEEEEEECCCCHHHH	40.83	27667366
107	Ubiquitination	RSIVPQTKSKAMPMS HCCCCCCCCCCCCCC	44.72	27667366
108	Phosphorylation	SIVPQTKSKAMPMSR CCCCCCCCCCCCCCC	29.09	24505115
114	Phosphorylation	KSKAMPMSRVSTVTK CCCCCCCCCEEECCH	24.53	24505115
121	Ubiquitination	SRVSTVTKSEVKVVA CCEEECCHHHCEEEE	40.04	27667366
125	Ubiquitination	TVTKSEVKVVAVIEA ECCHHHCEEEEEEEH	27.26	23503661
143	Ubiquitination	SYAKSHDKANTGSRP HHHHHCCCCCCCCCC	37.81	29967540
148	Phosphorylation	HDKANTGSRPDRREE CCCCCCCCCCCHHHC	38.30	-
156	Phosphorylation	RPDRREETSIGMKSS CCCHHHCCCCCCCCC	22.38	29083192
157	Phosphorylation	PDRREETSIGMKSSD CCHHHCCCCCCCCCC	22.03	29083192
206	Ubiquitination	PLPKIQEKPKPTHKP CCCCCCCCCCCCCCC	41.80	29967540
208	Ubiquitination	PKIQEKPKPTHKPTL CCCCCCCCCCCCCCE	73.87	29967540
212	Ubiquitination	EKPKPTHKPTLTIKQ CCCCCCCCCCEEEHH	42.02	29967540
282	Ubiquitination	YQTLAEIKKQIRQRE HHHHHHHHHHHHHHH	30.08	21906983
283	Ubiquitination	QTLAEIKKQIRQREK HHHHHHHHHHHHHHH	57.53	22817900
290	Ubiquitination	KQIRQREKYGPNPKA HHHHHHHHHCCCCCC	58.66	27667366
296	Ubiquitination	EKYGPNPKACHCKSR HHHCCCCCCCCCCCC	71.00	29967540
310	Ubiquitination	RGFSLEPKEFDKLVA CCCCCCHHHHHHHHH	62.73	21906983
314	Ubiquitination	LEPKEFDKLVALLKL CCHHHHHHHHHHHHH	50.62	21906983
322	O-linked_Glycosylation	LVALLKLTKDPFIHE HHHHHHHCCCHHHHH	31.64	29351928
322	Phosphorylation	LVALLKLTKDPFIHE HHHHHHHCCCHHHHH	31.64	29457462
332	O-linked_Glycosylation	PFIHEIATMIMGISP HHHHHHHHHHHCCCC	16.94	29351928
374	Phosphorylation	KEHPGALSMVDDSSE CCCCCCEEECCCCCC	19.07	-
398	Ubiquitination	SYIHQVCKGIISCPL HHHHHHHCHHHHCCC	55.05	29967540
461	Ubiquitination	KVFSCLSKNHANTRE HHHHHHCCCCCCHHH	39.54	29967540
484	Ubiquitination	SLVAPFNKNESKANI HHCCCCCCCCHHHHH	63.57	21906983
488	Ubiquitination	PFNKNESKANILNII CCCCCCHHHHHHHHH	38.99	22817900
510	Ubiquitination	FQFKTKAKLFTKEKF CCCCCCCEECCCCCC	45.77	27667366
514	Ubiquitination	TKAKLFTKEKFTKSE CCCEECCCCCCCHHH	52.12	22817900
516	Ubiquitination	AKLFTKEKFTKSELI CEECCCCCCCHHHHH	60.95	22817900
518	O-linked_Glycosylation	LFTKEKFTKSELISI ECCCCCCCHHHHHHH	44.74	29351928
519	Ubiquitination	FTKEKFTKSELISIF CCCCCCCHHHHHHHH	45.10	21906983
520	O-linked_Glycosylation	TKEKFTKSELISIFQ CCCCCCHHHHHHHHH	34.28	29351928
530	Ubiquitination	ISIFQEAKQFGQKLQ HHHHHHHHHHHHHHH	45.46	21906983
535	Ubiquitination	EAKQFGQKLQDLAEH HHHHHHHHHHHHHHC	48.79	21906983

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARMX5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARMX5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARMX5_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ARMX5_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.