| UniProt ID | RUN3B_HUMAN | |
|---|---|---|
| UniProt AC | Q96NL0 | |
| Protein Name | RUN domain-containing protein 3B | |
| Gene Name | RUNDC3B | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 473 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPSPGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MASRSLGGLS -----CCCCCCCCCC | 22.54 | - | |
| 10 | Phosphorylation | SRSLGGLSGIRGGGG CCCCCCCCCCCCCCC | 35.13 | 24719451 | |
| 13 | Methylation | LGGLSGIRGGGGGGG CCCCCCCCCCCCCCC | 41.03 | 30989279 | |
| 21 | Sumoylation | GGGGGGGKKSLSARN CCCCCCCHHCHHHHH | 42.33 | - | |
| 21 | Sumoylation | GGGGGGGKKSLSARN CCCCCCCHHCHHHHH | 42.33 | - | |
| 224 | Phosphorylation | DYTPYLKYIQSSDSI ECCCHHHHHCCCCCC | 11.12 | 29978859 | |
| 227 | Phosphorylation | PYLKYIQSSDSISSD CHHHHHCCCCCCCCC | 26.93 | 29978859 | |
| 228 | Phosphorylation | YLKYIQSSDSISSDE HHHHHCCCCCCCCCH | 20.99 | 29978859 | |
| 230 | Phosphorylation | KYIQSSDSISSDEEE HHHCCCCCCCCCHHH | 26.73 | 29978859 | |
| 232 | Phosphorylation | IQSSDSISSDEEELR HCCCCCCCCCHHHHH | 35.37 | 23663014 | |
| 233 | Phosphorylation | QSSDSISSDEEELRT CCCCCCCCCHHHHHH | 47.58 | 23663014 | |
| 300 | Phosphorylation | RENQLSESVSQNKIL HHHHCCHHHHHCHHH | 24.56 | - | |
| 327 | Phosphorylation | LEKEQLEYIIVELQD HHHHHHHHHEEEHHH | 12.44 | 18452278 | |
| 432 | Phosphorylation | EGKEDTPSLLGLCGS CCCCCCHHHHHHHHH | 38.02 | - | |
| 460 | Phosphorylation | KSNDYLASPTTEMTS CCCCCCCCCCCCCCC | 21.86 | 19413330 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RUN3B_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RUN3B_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RUN3B_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of RUN3B_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-460, AND MASSSPECTROMETRY. | |
