UniProt ID | ITSN2_HUMAN | |
---|---|---|
UniProt AC | Q9NZM3 | |
Protein Name | Intersectin-2 | |
Gene Name | ITSN2 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 1697 | |
Subcellular Localization | Cytoplasm. | |
Protein Description | Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes. [PubMed: 23999003] | |
Protein Sequence | MMAQFPTAMNGGPNMWAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPLISARFGMGSMPNLSIPQPLPPAAPITSLSSATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQPLPIPYSSSTLPHGSSYSLMMGGFGGASIQKAQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKCGNMDDSVLQCLLSLLSCLNNLFLLLKELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGRGWFPKSYVKIIPGSEVKREEPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVKMTTDSDPSQQWCADLQTLDTMQPIERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHGFLFNDFLLLTYMVKQFAVSSGSEKLFSSKSNAQFKMYKTPIFLNEVLVKLPTDPSSDEPVFHISHIDRVYTLRTDNINERTAWVQKIKAASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACKPNGKSNPYCEISMGSQSYTTRTIQDTLNPKWNFNCQFFIKDLYQDVLCLTLFDRDQFSPDDFLGRTEIPVAKIRTEQESKGPMTRRLLLHEVPTGEVWVRFDLQLFEQKTLL | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
7 | Phosphorylation | -MMAQFPTAMNGGPN -CCCCCCCCCCCCCC | 39.57 | 20068231 | |
19 | Phosphorylation | GPNMWAITSEERTKH CCCCEEECHHHHCCC | 23.49 | 20068231 | |
20 | Phosphorylation | PNMWAITSEERTKHD CCCEEECHHHHCCCH | 31.20 | 20068231 | |
24 | Phosphorylation | AITSEERTKHDRQFD EECHHHHCCCHHCCC | 35.69 | 20068231 | |
36 | Phosphorylation | QFDNLKPSGGYITGD CCCCCCCCCCCCCHH | 43.17 | 28152594 | |
39 | Phosphorylation | NLKPSGGYITGDQAR CCCCCCCCCCHHHHH | 9.99 | 20090780 | |
41 | Phosphorylation | KPSGGYITGDQARNF CCCCCCCCHHHHHHH | 26.65 | 28152594 | |
89 | Ubiquitination | AMKLIKLKLQGQQLP HHHHHHHHHCCCCCC | 33.49 | - | |
110 | Phosphorylation | MKQPPMFSPLISARF HCCCCCCHHHCHHCC | 16.73 | 30266825 | |
114 | Phosphorylation | PMFSPLISARFGMGS CCCHHHCHHCCCCCC | 22.52 | 23403867 | |
126 | O-linked_Glycosylation | MGSMPNLSIPQPLPP CCCCCCCCCCCCCCC | 38.57 | 30059200 | |
138 | O-linked_Glycosylation | LPPAAPITSLSSATS CCCCCCCCCCCCCCC | 23.66 | 30059200 | |
139 | O-linked_Glycosylation | PPAAPITSLSSATSG CCCCCCCCCCCCCCC | 27.29 | 30059200 | |
183 | O-linked_Glycosylation | QPLPIPYSSSTLPHG CCCCCCCCCCCCCCC | 16.68 | 30059200 | |
184 | O-linked_Glycosylation | PLPIPYSSSTLPHGS CCCCCCCCCCCCCCC | 22.84 | 30059200 | |
185 | O-linked_Glycosylation | LPIPYSSSTLPHGSS CCCCCCCCCCCCCCC | 28.20 | 30059200 | |
186 | O-linked_Glycosylation | PIPYSSSTLPHGSSY CCCCCCCCCCCCCCE | 46.38 | 30059200 | |
191 | O-linked_Glycosylation | SSTLPHGSSYSLMMG CCCCCCCCCEEECCC | 24.06 | 30059200 | |
192 | O-linked_Glycosylation | STLPHGSSYSLMMGG CCCCCCCCEEECCCC | 24.27 | 30059200 | |
193 | Phosphorylation | TLPHGSSYSLMMGGF CCCCCCCEEECCCCC | 13.92 | - | |
210 | Phosphorylation | ASIQKAQSLIDLGSS HHHHHHHHHHHCCCC | 31.95 | 23401153 | |
216 | O-linked_Glycosylation | QSLIDLGSSSSTSST HHHHHCCCCCCCCCC | 34.05 | 30059200 | |
216 | Phosphorylation | QSLIDLGSSSSTSST HHHHHCCCCCCCCCC | 34.05 | 29255136 | |
217 | Phosphorylation | SLIDLGSSSSTSSTA HHHHCCCCCCCCCCC | 26.89 | 29255136 | |
218 | Phosphorylation | LIDLGSSSSTSSTAS HHHCCCCCCCCCCCC | 39.06 | 29255136 | |
219 | Phosphorylation | IDLGSSSSTSSTASL HHCCCCCCCCCCCCC | 33.97 | 29255136 | |
220 | O-linked_Glycosylation | DLGSSSSTSSTASLS HCCCCCCCCCCCCCC | 28.75 | 30059200 | |
220 | Phosphorylation | DLGSSSSTSSTASLS HCCCCCCCCCCCCCC | 28.75 | 29255136 | |
221 | Phosphorylation | LGSSSSTSSTASLSG CCCCCCCCCCCCCCC | 27.86 | 23403867 | |
222 | O-linked_Glycosylation | GSSSSTSSTASLSGN CCCCCCCCCCCCCCC | 28.25 | 30059200 | |
222 | Phosphorylation | GSSSSTSSTASLSGN CCCCCCCCCCCCCCC | 28.25 | 23403867 | |
223 | Phosphorylation | SSSSTSSTASLSGNS CCCCCCCCCCCCCCC | 21.74 | 23403867 | |
225 | Phosphorylation | SSTSSTASLSGNSPK CCCCCCCCCCCCCCC | 24.13 | 23403867 | |
227 | Phosphorylation | TSSTASLSGNSPKTG CCCCCCCCCCCCCCC | 33.17 | 23403867 | |
230 | O-linked_Glycosylation | TASLSGNSPKTGTSE CCCCCCCCCCCCCCC | 31.16 | 30059200 | |
230 | Phosphorylation | TASLSGNSPKTGTSE CCCCCCCCCCCCCCC | 31.16 | 25159151 | |
233 | Phosphorylation | LSGNSPKTGTSEWAV CCCCCCCCCCCCCCC | 49.42 | - | |
244 | Phosphorylation | EWAVPQPTRLKYRQK CCCCCCCCCCHHHHH | 43.30 | - | |
248 | Phosphorylation | PQPTRLKYRQKFNTL CCCCCCHHHHHHHCC | 23.91 | - | |
254 | Phosphorylation | KYRQKFNTLDKSMSG HHHHHHHCCCHHHHH | 39.19 | 28060719 | |
258 | Phosphorylation | KFNTLDKSMSGYLSG HHHCCCHHHHHHHHH | 20.18 | 24275569 | |
260 | Phosphorylation | NTLDKSMSGYLSGFQ HCCCHHHHHHHHHHH | 31.23 | 19060867 | |
262 | Phosphorylation | LDKSMSGYLSGFQAR CCHHHHHHHHHHHHH | 7.15 | 20090780 | |
278 | Phosphorylation | ALLQSNLSQTQLATI HHHHCCCCHHHHHHE | 35.12 | 27251275 | |
280 | Phosphorylation | LQSNLSQTQLATIWT HHCCCCHHHHHHEEE | 23.36 | 27251275 | |
330 | Phosphorylation | PPELVPPSFRGGKQI CHHHCCCCCCCCCCC | 22.85 | 22210691 | |
335 | Acetylation | PPSFRGGKQIDSING CCCCCCCCCCCCCCC | 47.07 | 26051181 | |
339 | Phosphorylation | RGGKQIDSINGTLPS CCCCCCCCCCCCCCC | 21.41 | 22210691 | |
343 | Phosphorylation | QIDSINGTLPSYQKM CCCCCCCCCCCHHHH | 30.89 | - | |
346 | Phosphorylation | SINGTLPSYQKMQEE CCCCCCCCHHHHHCC | 43.22 | 30576142 | |
347 | Phosphorylation | INGTLPSYQKMQEEE CCCCCCCHHHHHCCC | 15.37 | 30576142 | |
358 | Ubiquitination | QEEEPQKKLPVTFED HCCCCCCCCCCCHHH | 53.42 | - | |
424 | Acetylation | KKQLELEKRLEKQRE HHHHHHHHHHHHHHH | 74.94 | 8260223 | |
428 | Acetylation | ELEKRLEKQRELERQ HHHHHHHHHHHHHHH | 60.28 | 8260235 | |
552 | Phosphorylation | QEYQNKLIYLVPEKQ HHHHHHHHHHCCHHH | 2.39 | 19605366 | |
553 | Phosphorylation | EYQNKLIYLVPEKQL HHHHHHHHHCCHHHH | 16.45 | 25159151 | |
565 (in isoform 4) | Ubiquitination | - | 2.85 | 21890473 | |
566 | Ubiquitination | QLLNERIKNMQFSNT HHHHHHHHCCCCCCC | 53.22 | 21890473 | |
571 | Phosphorylation | RIKNMQFSNTPDSGV HHHCCCCCCCCCCCC | 23.93 | 22199227 | |
573 | Phosphorylation | KNMQFSNTPDSGVSL HCCCCCCCCCCCCHH | 27.55 | 25159151 | |
576 | Phosphorylation | QFSNTPDSGVSLLHK CCCCCCCCCCHHHHH | 42.15 | 22199227 | |
579 | Phosphorylation | NTPDSGVSLLHKKSL CCCCCCCHHHHHHHC | 28.83 | 22199227 | |
582 (in isoform 4) | Ubiquitination | - | 40.57 | 21890473 | |
583 | Acetylation | SGVSLLHKKSLEKEE CCCHHHHHHHCCHHH | 43.99 | 26051181 | |
583 | Ubiquitination | SGVSLLHKKSLEKEE CCCHHHHHHHCCHHH | 43.99 | 21890473 | |
583 (in isoform 1) | Ubiquitination | - | 43.99 | 21890473 | |
583 (in isoform 2) | Ubiquitination | - | 43.99 | 21890473 | |
583 (in isoform 3) | Ubiquitination | - | 43.99 | 21890473 | |
584 | Ubiquitination | GVSLLHKKSLEKEEL CCHHHHHHHCCHHHH | 49.91 | - | |
588 | Acetylation | LHKKSLEKEELCQRL HHHHHCCHHHHHHHH | 62.88 | 26051181 | |
596 | Acetylation | EELCQRLKEQLDALE HHHHHHHHHHHHHHH | 45.67 | 26051181 | |
596 | Ubiquitination | EELCQRLKEQLDALE HHHHHHHHHHHHHHH | 45.67 | - | |
613 | Sulfoxidation | TASKLSEMDSFNNQL HHHHHHHHHHHCCCC | 4.74 | 21406390 | |
665 | Phosphorylation | QLALEQLYKIKRDKL HHHHHHHHHHCHHHH | 15.46 | 25147952 | |
700 | Ubiquitination | ARKAKQGKENLWKEN HHHHHHHHHHHHHHH | 40.72 | - | |
705 | Ubiquitination | QGKENLWKENLRKEE HHHHHHHHHHHHHHH | 39.63 | - | |
747 | Ubiquitination | RKDKDTLKAEEKKRE HHCHHHHHHHHHHHH | 56.71 | - | |
755 | Phosphorylation | AEEKKRETASVLVNY HHHHHHHHHHHHEEE | 28.41 | 22210691 | |
757 | Phosphorylation | EKKRETASVLVNYRA HHHHHHHHHHEEEEE | 24.33 | 22210691 | |
762 | Phosphorylation | TASVLVNYRALYPFE HHHHHEEEEECCCCC | 6.98 | 28509920 | |
766 | Phosphorylation | LVNYRALYPFEARNH HEEEEECCCCCCCCC | 12.61 | 24043423 | |
777 | Phosphorylation | ARNHDEMSFNSGDII CCCCCCCCCCCCCEE | 21.16 | 30108239 | |
780 | Phosphorylation | HDEMSFNSGDIIQVD CCCCCCCCCCEEEEC | 35.51 | 30108239 | |
818 | Phosphorylation | NYVEKMPSSENEKAV CCEEECCCCCCCCCC | 46.95 | 26657352 | |
826 | Phosphorylation | SENEKAVSPKKALLP CCCCCCCCCCCCCCC | 35.54 | 27422710 | |
859 | Phosphorylation | QPASVTDYQNVSFSN CCCCCCCCCCCEEEC | 7.82 | 15592455 | |
877 | Phosphorylation | NTSWQKKSAFTRTVS ECCCEECCCEEEEEC | 35.33 | 29514088 | |
880 | Phosphorylation | WQKKSAFTRTVSPGS CEECCCEEEEECCCC | 25.75 | 26074081 | |
882 | Phosphorylation | KKSAFTRTVSPGSVS ECCCEEEEECCCCCC | 23.44 | 29255136 | |
883 | Phosphorylation | KSAFTRTVSPGSVSP CCCEEEEECCCCCCC | 6.15 | 18669648 | |
884 | Phosphorylation | SAFTRTVSPGSVSPI CCEEEEECCCCCCCC | 23.95 | 29255136 | |
886 | Phosphorylation | FTRTVSPGSVSPIHG EEEEECCCCCCCCCC | 32.92 | 18669648 | |
887 | Phosphorylation | TRTVSPGSVSPIHGQ EEEECCCCCCCCCCC | 23.86 | 29255136 | |
888 | Phosphorylation | RTVSPGSVSPIHGQG EEECCCCCCCCCCCC | 11.06 | 18669648 | |
889 | Phosphorylation | TVSPGSVSPIHGQGQ EECCCCCCCCCCCCH | 21.60 | 29255136 | |
908 | Phosphorylation | LKAQALCSWTAKKDN HHHHHHHHHCCCCCC | 28.45 | 25159151 | |
913 | Ubiquitination | LCSWTAKKDNHLNFS HHHHCCCCCCCCCCC | 62.39 | - | |
949 | Phosphorylation | GRGWFPKSYVKIIPG CCCCCCHHHEEEECC | 35.08 | 29083192 | |
950 | Phosphorylation | RGWFPKSYVKIIPGS CCCCCHHHEEEECCC | 16.34 | 29083192 | |
952 | Ubiquitination | WFPKSYVKIIPGSEV CCCHHHEEEECCCHH | 27.04 | - | |
957 | Phosphorylation | YVKIIPGSEVKREEP HEEEECCCHHCCCCC | 33.58 | 28152594 | |
967 | Phosphorylation | KREEPEALYAAVNKK CCCCCHHHHHHHHCC | 2.59 | 19605366 | |
968 | Phosphorylation | REEPEALYAAVNKKP CCCCHHHHHHHHCCC | 10.28 | 25159151 | |
1041 | Phosphorylation | VKPKDQESFGSASKS CCCCCHHCCCCCCCC | 29.31 | 21815630 | |
1044 | Phosphorylation | KDQESFGSASKSGAS CCHHCCCCCCCCCCC | 27.62 | 21815630 | |
1046 | Phosphorylation | QESFGSASKSGASNK HHCCCCCCCCCCCCC | 29.11 | 21815630 | |
1051 | Phosphorylation | SASKSGASNKKPEIA CCCCCCCCCCCCCHH | 53.35 | 21712546 | |
1118 | Phosphorylation | HVKLLGPSSERATPA HHEEECCCCCCCCCC | 42.93 | 21722762 | |
1119 | Phosphorylation | VKLLGPSSERATPAF HEEECCCCCCCCCCC | 33.95 | 21722762 | |
1123 | Phosphorylation | GPSSERATPAFHPVC CCCCCCCCCCCCHHH | 22.75 | 25159151 | |
1147 | Phosphorylation | ANNEDELSFSKGQLI CCCCCCCCCCCCCEE | 25.98 | 24719451 | |
1241 (in isoform 3) | Phosphorylation | - | 41.89 | 20068231 | |
1242 | Phosphorylation | FQKRMAESGFLTEGE HHHHHHHCCCCCCCC | 25.88 | 20068231 | |
1242 (in isoform 3) | Phosphorylation | - | 25.88 | 20068231 | |
1246 | Phosphorylation | MAESGFLTEGEMALI HHHCCCCCCCCEEEE | 39.42 | 20068231 | |
1249 (in isoform 3) | Phosphorylation | - | 18.30 | 20068231 | |
1263 | Phosphorylation | NWKELIMSNTKLLKA CHHHHHHCCHHHHHH | 34.06 | 20068231 | |
1265 | Phosphorylation | KELIMSNTKLLKALR HHHHHCCHHHHHHHH | 18.76 | 20068231 | |
1277 | Phosphorylation | ALRVRKKTGGEKMPV HHHHHHHCCCCCCCH | 54.15 | - | |
1319 | Phosphorylation | AALLQQKTDEDTDFK HHHHCCCCCCCCCHH | 40.04 | 29759185 | |
1323 | Phosphorylation | QQKTDEDTDFKEFLK CCCCCCCCCHHHHHH | 41.09 | 29396449 | |
1376 | Phosphorylation | PESHADHSSLKLALE CCCCCCCHHHHHHHH | 37.60 | 22210691 | |
1377 | Phosphorylation | ESHADHSSLKLALER CCCCCCHHHHHHHHH | 26.55 | 22210691 | |
1479 | Phosphorylation | SGSEKLFSSKSNAQF CCCHHHHCCCCCCCC | 47.49 | 28152594 | |
1480 | Phosphorylation | GSEKLFSSKSNAQFK CCHHHHCCCCCCCCE | 32.54 | 28152594 | |
1482 | Phosphorylation | EKLFSSKSNAQFKMY HHHHCCCCCCCCEEE | 39.07 | 28152594 | |
1523 | Phosphorylation | SHIDRVYTLRTDNIN EEECEEEEEECCCCC | 13.60 | 24719451 | |
1590 | Phosphorylation | ACKPNGKSNPYCEIS ECCCCCCCCCCEEEE | 44.42 | 29209046 | |
1593 | Phosphorylation | PNGKSNPYCEISMGS CCCCCCCCEEEECCC | 13.63 | 29209046 | |
1597 | Phosphorylation | SNPYCEISMGSQSYT CCCCEEEECCCCCEE | 8.52 | 29209046 | |
1600 | Phosphorylation | YCEISMGSQSYTTRT CEEEECCCCCEEECC | 13.81 | 25954137 | |
1602 | Phosphorylation | EISMGSQSYTTRTIQ EEECCCCCEEECCHH | 26.58 | 25954137 | |
1603 | Phosphorylation | ISMGSQSYTTRTIQD EECCCCCEEECCHHH | 12.42 | 25954137 | |
1604 | Phosphorylation | SMGSQSYTTRTIQDT ECCCCCEEECCHHHH | 18.30 | 29209046 | |
1605 | Phosphorylation | MGSQSYTTRTIQDTL CCCCCEEECCHHHHC | 19.99 | 29209046 | |
1643 | Phosphorylation | LFDRDQFSPDDFLGR CCCCCCCCCCCCCCC | 23.06 | 24076635 | |
1660 | Phosphorylation | IPVAKIRTEQESKGP CCEEEECCCCCCCCC | 45.56 | 23403867 | |
1664 | Phosphorylation | KIRTEQESKGPMTRR EECCCCCCCCCCCHH | 42.48 | 23403867 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ITSN2_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ITSN2_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ITSN2_HUMAN !! |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
There are no disease associations of PTM sites. | ||||||
OMIM Disease | ||||||
There are no disease associations of PTM sites. | ||||||
Kegg Drug | ||||||
There are no disease associations of PTM sites. | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-210; TYR-553; THR-882;SER-884; SER-889 AND TYR-968, AND MASS SPECTROMETRY. | |
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-884 AND SER-889, ANDMASS SPECTROMETRY. | |
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-884 AND SER-889, ANDMASS SPECTROMETRY. | |
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-884 AND SER-889, ANDMASS SPECTROMETRY. | |
"An extensive survey of tyrosine phosphorylation revealing new sitesin human mammary epithelial cells."; Heibeck T.H., Ding S.-J., Opresko L.K., Zhao R., Schepmoes A.A.,Yang F., Tolmachev A.V., Monroe M.E., Camp D.G. II, Smith R.D.,Wiley H.S., Qian W.-J.; J. Proteome Res. 8:3852-3861(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-968, AND MASSSPECTROMETRY. | |
"Multiple reaction monitoring for robust quantitative proteomicanalysis of cellular signaling networks."; Wolf-Yadlin A., Hautaniemi S., Lauffenburger D.A., White F.M.; Proc. Natl. Acad. Sci. U.S.A. 104:5860-5865(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-968, AND MASSSPECTROMETRY. | |
"Global survey of phosphotyrosine signaling identifies oncogenickinases in lung cancer."; Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J.,Lee K., Reeves C., Li Y., Hu Y., Tan Z., Stokes M., Sullivan L.,Mitchell J., Wetzel R., Macneill J., Ren J.M., Yuan J.,Bakalarski C.E., Villen J., Kornhauser J.M., Smith B., Li D., Zhou X.,Gygi S.P., Gu T.-L., Polakiewicz R.D., Rush J., Comb M.J.; Cell 131:1190-1203(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-553, AND MASSSPECTROMETRY. | |
"Immunoaffinity profiling of tyrosine phosphorylation in cancercells."; Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H.,Zha X.-M., Polakiewicz R.D., Comb M.J.; Nat. Biotechnol. 23:94-101(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-859 AND TYR-968, ANDMASS SPECTROMETRY. | |
"Time-resolved mass spectrometry of tyrosine phosphorylation sites inthe epidermal growth factor receptor signaling network reveals dynamicmodules."; Zhang Y., Wolf-Yadlin A., Ross P.L., Pappin D.J., Rush J.,Lauffenburger D.A., White F.M.; Mol. Cell. Proteomics 4:1240-1250(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-553, AND MASSSPECTROMETRY. | |
"Robust phosphoproteomic profiling of tyrosine phosphorylation sitesfrom human T cells using immobilized metal affinity chromatography andtandem mass spectrometry."; Brill L.M., Salomon A.R., Ficarro S.B., Mukherji M., Stettler-Gill M.,Peters E.C.; Anal. Chem. 76:2763-2772(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-968, AND MASSSPECTROMETRY. |